RAAS
Os inibidores do sistema renina-angiotensina-aldosterona (RAAS) são compostos que têm como alvo a via RAAS, conhecida principalmente por seu papel na regulação da pressão arterial e do equilíbrio de fluidos, mas que também influencia a angiogênese. A via RAAS pode contribuir para o desenvolvimento de novos vasos sanguíneos em tumores, apoiando assim seu crescimento. Inibir componentes do RAAS pode, portanto, ter efeitos antiangiogênicos, tornando esses inibidores valiosos no tratamento de certos tipos de câncer e distúrbios vasculares. Na CymitQuimica, oferecemos uma gama de inibidores de alta qualidade do RAAS para apoiar sua pesquisa em biologia cardiovascular, oncologia e angiogênese.
Foram encontrados 92 produtos para "RAAS".
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Olmesartan-D4
CAS:Olmesartan D4 is the deuterium labeled Olmesartan. Olmesartan is an antagonist of angiotensin II receptor (AT1R) used to treat high blood pressure.Fórmula:C24H26N6O3Pureza:98%Cor e Forma:SolidPeso molecular:450.526Angiogenin (108-122)
CAS:Angiogenin (108-122) peptide treats cancer, infectious, fibrotic, inflammatory, neurodegenerative, autoimmune, and heart diseases.Fórmula:C78H125N25O23Cor e Forma:SolidPeso molecular:1780.98PD 123319 ditrifluoroacetate
CAS:PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.Fórmula:C35H34F6N4O7Pureza:98%Cor e Forma:White SolidPeso molecular:736.66Azilsartan-D5
CAS:Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.Fórmula:C25H20N4O5Pureza:98%Cor e Forma:SolidPeso molecular:461.48Olmesartan
CAS:Olmesartan (RNH 6270) is an Angiotensin II Type I receptor antagonist.Fórmula:C24H26N6O3Pureza:91.89% - 99.81%Cor e Forma:White To Beige Solid SolidPeso molecular:446.50Aviptadil Acetate
CAS:Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs.Fórmula:C147H238N44O42S·C2H4O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:3385.9Angiotensin III, human, mouse
CAS:Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).Fórmula:C46H66N12O9Pureza:98.44%Cor e Forma:SolidPeso molecular:931.09ANGIOTENSIN IV TFA(12676-15-2(free base))
ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.Fórmula:C42H55F3N8O10Pureza:99.12%Cor e Forma:SolidPeso molecular:888.92Ref: TM-T7743
2mg40,00€5mg52,00€10mg92,00€1mL*10mM (DMSO)100,00€25mg159,00€50mg230,00€100mg341,00€200mg485,00€Acein acetate
ACE ligand with Kd 2.79 nM, inactive on ACE up to 500 nM. Boosts NMDA/D-serine-induced dopamine release in striatum.Fórmula:C45H72N10O15Pureza:99.43%Cor e Forma:SolidPeso molecular:993.11(Sar¹)-Angiotensin II acetate
(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor.Fórmula:C51H75N13O12Pureza:99.89%Cor e Forma:White SolidPeso molecular:1062.22Ref: TM-T35834L
1mg55,00€5mg110,00€10mg167,00€1mL*10mM (DMSO)193,00€25mg258,00€50mg366,00€100mg492,00€Novokinin acetate
Novokinin acetate binds AT2 receptor (Ki=7 nM); antihypertensive effect blocked by PD123319.Fórmula:C41H65N11O9Pureza:99.87%Cor e Forma:SolidPeso molecular:856.02Ref: TM-T23077L
1mg132,00€2mg177,00€5mg289,00€10mg414,00€1mL*10mM (DMSO)462,00€25mg642,00€50mg853,00€100mg1.161,00€200mg1.558,00€A 779 TFA(159432-28-7 free base)
A 779 TFA is a potent antagonist of angiotensin-(1-7) receptor.Fórmula:C41H61F3N12O13Pureza:99.55%Cor e Forma:SolidPeso molecular:987.01Azilsartan Medoxomil
CAS:Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adultsFórmula:C30H24N4O8Pureza:99.83%Cor e Forma:SolidPeso molecular:568.53Ref: TM-T6219
1mg38,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg113,00€25mg200,00€50mg334,00€100mg467,00€200mg643,00€Alamandine TFA
Alamandine TFA, a RAS peptide, binds MrgD receptors, has anti-hypertensive effects, and protects heart and kidneys.Fórmula:C42H63F3N12O11Pureza:99.99%Cor e Forma:SoildPeso molecular:969.02VTP-27999 TFA
CAS:VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).Fórmula:C28H42ClF3N4O7Pureza:98.84%Cor e Forma:SolidPeso molecular:639.1Eprosartan Mesylate
CAS:Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.Fórmula:C23H24N2O4S·CH4O3SPureza:99.72% - 99.93%Cor e Forma:A White To Off- White PowderPeso molecular:520.62Ref: TM-T2531
1mL*10mM (DMSO)39,00€10mg46,00€25mg65,00€50mg80,00€100mg104,00€200mg161,00€500mg263,00€Trans-Tranilast
CAS:Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It has been used for the treatment of allergic disorders such as atopic dermatitis.Fórmula:C18H17NO5Pureza:99.41% - ≥95%Cor e Forma:SolidPeso molecular:327.33Saralasin acetate(34273-10-4 free base)
CAS:Saralasin acetate is a Non-selective angiotensin II antagonist.Fórmula:C44H71N13O13Pureza:99.74%Cor e Forma:White SolidPeso molecular:990.11PD 123319
CAS:PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.Fórmula:C31H32N4O3Pureza:98.73% - 99.65%Cor e Forma:Yellow ViscousPeso molecular:508.61Ref: TM-T6067
2mg43,00€5mg77,00€1mL*10mM (DMSO)88,00€10mg105,00€25mg207,00€50mg270,00€100mg351,00€200mg500,00€Angiotensin 1/2 (5-7) acetate
Angiotensin 1/2 (5-7) acetate: a dipsogenic hormone peptide, sequence H2N-Ile-His-Pro-OH, from liver-produced angiotensinogen.Fórmula:C19H31N5O6Pureza:99.13%Cor e Forma:SolidPeso molecular:425.49
