RAAS

Os inibidores do sistema renina-angiotensina-aldosterona (RAAS) são compostos que têm como alvo a via RAAS, conhecida principalmente por seu papel na regulação da pressão arterial e do equilíbrio de fluidos, mas que também influencia a angiogênese. A via RAAS pode contribuir para o desenvolvimento de novos vasos sanguíneos em tumores, apoiando assim seu crescimento. Inibir componentes do RAAS pode, portanto, ter efeitos antiangiogênicos, tornando esses inibidores valiosos no tratamento de certos tipos de câncer e distúrbios vasculares. Na CymitQuimica, oferecemos uma gama de inibidores de alta qualidade do RAAS para apoiar sua pesquisa em biologia cardiovascular, oncologia e angiogênese.

Foram encontrados 98 produtos para "RAAS".

Filtrar por

Percentagem de pureza

100

produtos por página.

+ Info
Azilsartan-D5
CAS:
- 1346599-45-8
Azilsartan (TAK-536) D5 is the deuterium-labeled Azilsartan. Azilsartan is a specific antagonist of the angiotensin II type 1 receptor.
Fórmula:C₂₅H₂₀N₄O₅
Pureza:98%
Cor e Forma:Solid
Peso molecular:461.4809
Ref: TM-T10440
+ Info
Spirapril hydrochloride
CAS:
- 94841-17-5
Spirapril hydrochloride (SCH 33844 hydrochloride) is a potent angiotensin converting enzyme inhibitor with antihypertensive activity that competitively blocks the conversion of angiotensin I to angiotensin II, functions as an orally active proagent of spiraprilat, and is extensively utilized in cardiovascular research focused on hypertension and congestive heart failure pathophysiology and therapeutic intervention.
Fórmula:C₂₂H₃₁ClN₂O₅S₂
Pureza:99.78%
Cor e Forma:White Solid
Peso molecular:503.07
Ref: TM-T63425
+ Info
Anti-Human ACE2 Antibody (1Y227)
Anti-ACE2 Antibody (1Y227) is a Mouse IgG1 monoclonal antibody targeting Human ACE2.
Ref: TM-T9901A-677
+ Info
Losartan (D4 Carboxylic Acid)
CAS:
- 1246820-62-1
Losartan D4 Carboxylic Acid is the deuterium labeled Losartan, which is an angiotensin II receptor antagonist.
Fórmula:C₂₂H₂₁ClN₆O₂
Pureza:98%
Cor e Forma:Solid
Peso molecular:440.919
Ref: TM-T11869
+ Info
Valsartan-D9
CAS:
- 1089736-73-1
Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.
Fórmula:C₂₄H₂₉N₅O₃
Pureza:98%
Cor e Forma:Solid
Peso molecular:444.5742
Ref: TM-T13282
+ Info
Angiotensin II (3-8), human
CAS:
- 12676-15-2
Angiotensin II (3-8), human is a less effective agonist at the angiotensin AT1 receptor.
Cor e Forma:Transparent Solid
Ref: TM-T5824
+ Info
PD 123319 ditrifluoroacetate
CAS:
- 136676-91-0
PD 123319 ditrifluoroacetate is a selective non-peptide AT2 receptor antagonist with IC50 of 34 nM.
Fórmula:C₃₅H₃₄F₆N₄O₇
Pureza:99%
Cor e Forma:White Solid
Peso molecular:736.6575
Ref: TM-T12381
+ Info
Novokinin acetate
Novokinin acetate binds AT2 receptor (Ki=7 nM); antihypertensive effect blocked by PD123319.
Fórmula:C₄₁H₆₅N₁₁O₉
Pureza:99.87%
Cor e Forma:Solid
Peso molecular:856.02
Ref: TM-T23077L
+ Info
Aviptadil Acetate
CAS:
- 1444827-29-5
Aviptadil Acetate (Vasoactive Intestinal Peptide acetate salt) induces pulmonary vasodilation and inhibits the proliferation of vascular SMCs.
Fórmula:C₁₄₉H₂₄₂N₄₄O₄₄S
Pureza:>99.99%
Cor e Forma:Solid
Peso molecular:3385.849
Ref: TM-TP1016L
+ Info
Angiotensin III, human, mouse
CAS:
- 13602-53-4
Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA))(3TFA) is an endogenous angiotensin II receptor (AT2R) agonist(IC50s of 0.648 nM).
Fórmula:C₄₆H₆₆N₁₂O₉
Pureza:98.44%
Cor e Forma:Solid
Peso molecular:931.09
Ref: TM-T7577
+ Info
ANGIOTENSIN IV TFA
ANGIOTENSIN IV TFA is a less effective agonist at the angiotensin AT1 receptor.
Fórmula:C₄₂H₅₅F₃N₈O₁₀
Pureza:99.12%
Cor e Forma:Solid
Peso molecular:888.92
Ref: TM-T7743
+ Info
Acein acetate
ACE ligand with Kd 2.79 nM, inactive on ACE up to 500 nM. Boosts NMDA/D-serine-induced dopamine release in striatum.
Fórmula:C₄₅H₇₂N₁₀O₁₅
Pureza:99.43%
Cor e Forma:White Solid
Peso molecular:993.11
Ref: TM-TP1920L1
+ Info
(Sar¹)-Angiotensin II acetate
(Sar¹)-Angiotensin II acetate, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor.
Fórmula:C₅₁H₇₅N₁₃O₁₂
Pureza:99.89%
Cor e Forma:White Solid
Peso molecular:1062.22
Ref: TM-T35834L
+ Info
A 779 TFA
A 779 TFA is a potent antagonist of angiotensin-(1-7) receptor.
Fórmula:C₄₁H₆₁F₃N₁₂O₁₃
Pureza:99.55%
Cor e Forma:Solid
Peso molecular:987.01
Ref: TM-T7616L
+ Info
Azilsartan Medoxomil
CAS:
- 863031-21-4
Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults
Fórmula:C₃₀H₂₄N₄O₈
Pureza:99.83%
Cor e Forma:Solid
Peso molecular:568.53
Ref: TM-T6219
+ Info
Alamandine TFA
Alamandine TFA, a RAS peptide, binds MrgD receptors, has anti-hypertensive effects, and protects heart and kidneys.
Fórmula:C₄₂H₆₃F₃N₁₂O₁₁
Pureza:99.99%
Cor e Forma:Soild
Peso molecular:969.02
Ref: TM-T37496L
+ Info
VTP-27999 TFA
CAS:
- 1013937-63-7
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
Fórmula:C₂₈H₄₂ClF₃N₄O₇
Pureza:98.84%
Cor e Forma:Solid
Peso molecular:639.1
Ref: TM-T7668
+ Info
Eprosartan Mesylate
CAS:
- 144143-96-4
Eprosartan Mesylate (SKF-108566J) is a competitive and reversible Angiotensin II Receptor Blocker.
Fórmula:C₂₄H₂₈N₂O₇S₂
Pureza:99.72% - 99.93%
Cor e Forma:A White To Off- White Powder
Peso molecular:520.62
Ref: TM-T2531
+ Info
Trans-Tranilast
CAS:
- 70806-55-2
Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It has been used for the treatment of allergic disorders such as atopic dermatitis.
Fórmula:C₁₈H₁₇NO₅
Pureza:99.41% - ≥95%
Cor e Forma:Solid
Peso molecular:327.33
Ref: TM-T2270
+ Info
Saralasin acetate
CAS:
- 39698-78-7
Saralasin acetate is a Non-selective angiotensin II antagonist.
Fórmula:C₄₄H₇₁N₁₃O₁₃
Pureza:99.74%
Cor e Forma:White Solid
Peso molecular:990.1138
Ref: TM-TP1929L1