CCR
Os receptores de quimiocinas C-C (CCRs) são um grupo de GPCRs que respondem às quimiocinas, moléculas de sinalização que orientam a migração de células imunológicas para locais de inflamação ou infecção. Os CCRs desempenham papéis cruciais nas respostas imunológicas, inflamação e no desenvolvimento de várias doenças, incluindo distúrbios autoimunes e câncer. A modulação da atividade dos CCRs está sendo explorada como uma estratégia terapêutica para condições como artrite reumatoide, esclerose múltipla e infecção pelo HIV. Na CymitQuimica, oferecemos uma gama de moduladores de CCR de alta qualidade para apoiar sua pesquisa em imunologia, inflamação e desenvolvimento terapêutico.
Foram encontrados 147 produtos para "CCR".
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7,4'-Dihydroxyflavone
CAS:7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.Fórmula:C15H10O4Pureza:99.39% - 99.6%Cor e Forma:White SolidPeso molecular:254.24Vercirnon sodium
CAS:Vercirnon (GSK1605786A) sodium: oral CCR9 antagonist, inhibits Ca2+ mobilization/chemotaxis, IC50 = 2.6-5.4 nM, selective for CCR9 vs. CCR1-12/CX3CR1-7.Fórmula:C22H21ClN2NaO4SCor e Forma:SolidPeso molecular:467.92Cenicriviroc
CAS:Cenicriviroc (TAK-652), oral CCR2/CCR5 blocker, inhibits HIV-1/HIV-2, with strong anti-infective/anti-inflammatory effects.Fórmula:C41H52N4O4SPureza:97.87%Cor e Forma:Yellow SolidPeso molecular:696.94Ref: TM-TQ0297
1mg63,00€2mg90,00€5mg133,00€1mL*10mM (DMSO)200,00€10mg212,00€25mg423,00€50mg550,00€100mg715,00€200mg964,00€AZD2098
CAS:AZD2098 is a potent CC-chemokine receptor 4 (CCR4) inhibitor used for asthma research.Fórmula:C11H9Cl2N3O3SPureza:99.80% - 99.94%Cor e Forma:SolidPeso molecular:334.18Ref: TM-T4300
1mg34,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg105,00€25mg217,00€50mg334,00€100mg502,00€500mg1.063,00€DAPTA
CAS:DAPTA (Adaptavir) is an inhibitor of CCR5, shows potent anti-HIV activities.Fórmula:C35H56N10O15Pureza:>99.99%Cor e Forma:White SolidPeso molecular:856.88BMS-813160
CAS:BMS-813160 is the first dual CCR2/CCR5 antagonist to enter Clinical development for cardiovascular.Fórmula:C25H40N8O2Pureza:99.66% - 99.79%Cor e Forma:SolidPeso molecular:484.64Ref: TM-T4584
1mg59,00€5mg130,00€1mL*10mM (DMSO)138,00€10mg177,00€25mg324,00€50mg537,00€100mg767,00€500mg1.558,00€Vicriviroc
CAS:Vicriviroc, also known as MK4176 is a CCR5 antagonist.Fórmula:C28H38F3N5O2Cor e Forma:SolidPeso molecular:533.63Bindarit
CAS:Bindarit is a selective inhibitor of monocyte chemoattractant proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.Cost-effective and quality-assured.Fórmula:C19H20N2O3Pureza:98.35% - 98.55%Cor e Forma:SolidPeso molecular:324.37Ref: TM-T6413
1mg35,00€2mg50,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg110,00€25mg178,00€50mg314,00€100mg492,00€200mg710,00€SB297006
CAS:SB297006 is an antagonist of C-C chemokine receptor 3, which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1δ.Fórmula:C18H18N2O5Pureza:99.59%Cor e Forma:White SolidPeso molecular:342.35BX471
CAS:BX471 (BX 471) is a potent, selective non-peptide CCR1 antagonist.Fórmula:C21H24ClFN4O3Pureza:98% - 99.98%Cor e Forma:SolidPeso molecular:434.89Ref: TM-T2375
1mg35,00€5mg86,00€1mL*10mM (DMSO)95,00€10mg117,00€25mg200,00€50mg313,00€100mg489,00€200mg740,00€R243
CAS:R243 is CCR8 signaling and chemotaxis inhibitor.Fórmula:C21H27NO4Pureza:99.03% - 99.16%Cor e Forma:Yellow SolidPeso molecular:357.44Ref: TM-T24700
1mg40,00€2mg52,00€5mg80,00€1mL*10mM (DMSO)90,00€10mg117,00€25mg207,00€50mg333,00€100mg495,00€TAK-779
CAS:TAK-779 (Takeda 779) is an antagonist of chemokine receptor 5 (CCR5), CCR2b, and CXC chemokine receptor 3 (CXCR3).Fórmula:C33H39ClN2O2Pureza:99.21%Cor e Forma:SolidPeso molecular:531.13INCB 3284
CAS:INCB 3284, a potent human CCR2 antagonist with an IC50 of 3.7 nM, is researchable for acute liver failure and inhibits MCP-1/hCCR2 binding.Fórmula:C26H31F3N4O4Pureza:97.81% - 99.46%Cor e Forma:SolidPeso molecular:520.54Carlumab
CAS:Carlumab is a high-affinity human monoclonal antibody that targets CCL2, suppressing the recruitment of monocytes/macrophages in the tumour microenvironment.Pureza:95%Cor e Forma:Transparent LiquidPeso molecular:144.87 kDaAnti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5)
Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) is a monoclonal antibody targeting mouse/human/rat CCL2/MCP-1, capable of blocking the CCL2 signalling pathway.Pureza:99% - 99%Cor e Forma:Transparent LiquidPeso molecular:150 kDaTivumecirnon
CAS:Tivumecirnon (FLX475) is a selective and oral CCR4 antagonist inhibits the infiltration and migration of Treg into the tumour microenvironment, antitumourFórmula:C24H27Cl2F3N6OPureza:99.88%Cor e Forma:SolidPeso molecular:543.41Ref: TM-T69834
1mg158,00€5mg385,00€1mL*10mM (DMSO)462,00€10mg625,00€25mg1.251,00€50mg2.008,00€100mg2.790,00€JNJ-27141491
CAS:JNJ-27141491 is a potent, noncompetitive antagonist of human CCR2.Fórmula:C17H15F2N3O3SPureza:98%Cor e Forma:SolidPeso molecular:379.38PNU-177864 hydrochloride
CAS:PNU-177864 hydrochloride is a potent, selective and orally active antagonist of dopamine D3 receptor.Fórmula:C18H22ClF3N2O3SPureza:99.95%Cor e Forma:SolidPeso molecular:438.89CCR1 antagonist 7
CAS:CCR1 antagonist 7 (compound 16r) is an antagonist of chemokine receptor 1 (CCR1) with an IC 50 of 4 nM [1].Fórmula:C21H24ClN5O3SPureza:98%Cor e Forma:SolidPeso molecular:461.96BMS-457
CAS:BMS-457 is a potent, CCR1-selective antagonist.Fórmula:C24H35ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:451
