p38 MAPK
As p38 MAPKs são um subgrupo de MAPKs que respondem a sinais de estresse e estão envolvidas na regulação da inflamação, diferenciação celular, apoptose e autofagia. A sinalização de p38 MAPK é crucial nas respostas imunes e está implicada em várias doenças, incluindo condições inflamatórias crônicas, câncer e distúrbios neurodegenerativos. Na CymitQuimica, oferecemos uma gama abrangente de inibidores e moduladores de p38 MAPK para apoiar sua pesquisa em inflamação, resposta ao estresse e desenvolvimento terapêutico.
Foram encontrados 115 produtos para "p38 MAPK".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Rotundic acid
CAS:Rotundic acid fights various cancers: HepG2, A375, NCI-H446, MCF-7, and HT-29.Fórmula:C30H48O5Pureza:96.91% - 99.97%Cor e Forma:White SolidPeso molecular:488.70Ref: TM-T5S0506
2mg34,00€5mg49,00€1mL*10mM (DMSO)49,00€10mg75,00€25mg137,00€50mg215,00€100mg319,00€200mg474,00€Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Fórmula:C24H30O14Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:542.49Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Fórmula:C20H15Cl3N2OSPureza:99.48%Cor e Forma:White SolidPeso molecular:437.77Ref: TM-T50005
5mg55,00€10mg78,00€1mL*10mM (DMSO)79,00€25mg119,00€50mg172,00€100mg259,00€200mg388,00€Andrograpanin
CAS:Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.Fórmula:C20H30O3Pureza:99.03% - 99.45%Cor e Forma:SolidPeso molecular:318.45FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Fórmula:C11H12O4Pureza:99.66% - 99.95%Cor e Forma:SolidPeso molecular:208.21BMS-582949 hydrochloride
CAS:The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).Fórmula:C22H27ClN6O2Pureza:97.57% - 98.75%Cor e Forma:White SolidPeso molecular:442.95Ref: TM-T3462
1mg34,00€5mg67,00€1mL*10mM (DMSO)73,00€10mg96,00€25mg161,00€50mg250,00€100mg371,00€200mg523,00€R1487
CAS:R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.Fórmula:C19H18F2N4O3Pureza:99.77%Cor e Forma:SolidPeso molecular:388.37SR-318
CAS:SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).Fórmula:C27H33N5O2Pureza:99.74%Cor e Forma:SolidPeso molecular:459.58Ref: TM-T12997
2mg35,00€5mg55,00€1mL*10mM (DMSO)55,00€10mg92,00€25mg166,00€50mg259,00€100mg371,00€200mg533,00€Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Cor e Forma:White SolidPeso molecular:718.08TA-02
CAS:TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.Fórmula:C20H13F2N3Pureza:99.66% - 99.79%Cor e Forma:SolidPeso molecular:333.33Ref: TM-T4646
500mgA consultar5mg37,00€1mL*10mM (DMSO)40,00€10mg55,00€25mg99,00€50mg152,00€100mg230,00€TA-01
CAS:TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.Fórmula:C20H12F3N3Pureza:99.55% - 99.94%Cor e Forma:SolidPeso molecular:351.32Ref: TM-T4645
2mg34,00€5mg50,00€1mL*10mM (DMSO)67,00€10mg80,00€25mg147,00€50mg224,00€100mg313,00€200mg439,00€Ralimetinib dimesylate
CAS:Ralimetinib dimesylate (LY2228820 dimesylate) is a orally available, p38 MAPK inhibitor with potential anti-inflammatory and antineoplastic activities.Fórmula:C24H29FN6·2CH4O3SPureza:98% - 99.38%Cor e Forma:White SolidPeso molecular:612.74Skepinone-L
CAS:Skepinone-L (CBS3830) is a selective p38 mitogen-activated protein kinase inhibitor.Fórmula:C24H21F2NO4Pureza:99.56% - >99.99%Cor e Forma:SolidPeso molecular:425.42Ref: TM-T6130
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg197,00€50mg296,00€100mg440,00€SKF-86002
CAS:SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Fórmula:C16H12FN3SPureza:98% - 99.85%Cor e Forma:SolidPeso molecular:297.35SB 242235
CAS:SB 242235 is a potent and selective p38 MAP kinase inhibitor that may be an effective therapy for cytokine-mediated diseases.Fórmula:C19H20FN5OPureza:99.14% - 99.68%Cor e Forma:Yellow SolidPeso molecular:353.39Rhoifolin
CAS:Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.Fórmula:C27H30O14Pureza:98.11% - 98.58%Cor e Forma:SolidPeso molecular:578.52TAK-715
CAS:TAK-715 is a p38 MAPK inhibitor for p38α.Fórmula:C24H21N3OSPureza:99.83%Cor e Forma:White SolidPeso molecular:399.51Ref: TM-T6150
1mg38,00€2mg50,00€5mg82,00€1mL*10mM (DMSO)92,00€10mg94,00€25mg166,00€50mg306,00€100mg480,00€PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Fórmula:C20H13FN4O2Pureza:98.65%Cor e Forma:Yellow SolidPeso molecular:360.34AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Fórmula:C29H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:535.56Acumapimod
CAS:Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Fórmula:C22H19N5O2Pureza:≥95%Cor e Forma:SolidPeso molecular:385.42
