Canal de cloreto
Os canais de cloreto são proteínas de membrana que controlam o movimento dos íons cloreto através das membranas celulares, desempenhando um papel vital na manutenção do volume celular, excitabilidade elétrica e equilíbrio ácido-base. A desregulação dos canais de cloreto está associada a doenças como fibrose cística, epilepsia e distúrbios renais. Na CymitQuimica, oferecemos uma variedade de moduladores de canais de cloreto para apoiar sua pesquisa em transporte de íons, homeostase celular e mecanismos de doenças.
Foram encontrados 55 produtos para "Canal de cloreto".
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Meticrane
CAS:Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.Fórmula:C10H13NO4S2Pureza:99.16%Cor e Forma:SolidPeso molecular:275.345Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Fórmula:C14H10F3NO2Pureza:98.68%Cor e Forma:White SolidPeso molecular:281.2299Halothane
CAS:Halothane (Anestan) 可以减弱内皮依赖性舒张作用。Fórmula:C2HBrClF3Pureza:99.80% - >99.99%Cor e Forma:SolidPeso molecular:197.382T16Ainh-A01
CAS:T16Ainh-A01 is a potent TMEM16A chloride channel inhibitor with a 1 μM IC50, targeting CaCC.Fórmula:C19H20N4O3S2Pureza:97.18% - 98.15%Cor e Forma:SolidPeso molecular:416.52NS1652
CAS:NS1652 is an anion conductance inhibitor. NS1652 blocks chloride channel has an IC50 of 1.6 μM in human and mouse red blood cells.Fórmula:C15H11F3N2O3Pureza:99.62%Cor e Forma:SolidPeso molecular:324.2546Eact
CAS:Eact is a potent TMEM16A activator that also triggers TRPV1, causing itch, pain, and heat sensitivity.Fórmula:C22H24N2O5SPureza:98.14%Cor e Forma:SolidPeso molecular:428.5Endovion
CAS:Endovion (NS3728) is a pharmacological anion channel and an Anoctamin-1 (ANO 1) channel inhibitor. Endovion is also the specific VRAC/VSOAC blocker.Fórmula:C16H9BrF6N6OPureza:98.51%Cor e Forma:SolidPeso molecular:495.177Niflumic acid
CAS:Niflumic acid (Nifluril) is a Ca2+-activated Cl- channel blocker and an analgesic and anti-inflammatory agent used in the therapy of rheumatoid arthritis.Fórmula:C13H9F3N2O2Pureza:99.47%Cor e Forma:SolidPeso molecular:282.218Afoxolaner
CAS:Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.Fórmula:C26H17ClF9N3O3Pureza:99.1% - 99.38%Cor e Forma:SolidPeso molecular:625.87DCPIB
CAS:DCPIB, a known specific and potent inhibitor of volume-regulated anion channels (VRAC),DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μMFórmula:C22H28Cl2O4Pureza:99.77% - 99.79%Cor e Forma:SolidPeso molecular:427.36Chlorotoxin TFA
Chlorotoxin TFA, a scorpion venom peptide, blocks chloride channels and has anti-cancer properties.Fórmula:C160H250F3N53O49S11Cor e Forma:SolidPeso molecular:4109.74GaTx2
CAS:High-affinity ClC-2 blocker (KD ~50 pM), selective over other ClCs/CFTR/GABAC/CaCC/KV1.2; slows activation, no effect on open channels.Fórmula:C125H199N39O47S6Pureza:98%Cor e Forma:SolidPeso molecular:3192.54Ion Channel Targeted Library
A unique collection of xnum compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;Cor e Forma:Odour SolidLamotrigine-13CD3
CAS:Lamotrigine-13CD3 is the 13C and deuterium labeled Lamotrigine. Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer. The physiologic effect of lamotrigine is by means of Decreased Central Nervous System Disorganized Electrical Activity.Fórmula:C9H7Cl2N5Peso molecular:260.10Umifoxolaner
CAS:Umifoxolaner is an anti-parasitic agent (veterinary).Fórmula:C26H16ClF10N3O3Cor e Forma:SolidPeso molecular:643.87Chlorotoxin(linear)
Chlorotoxin(linear): 36-amino-acid peptide from Egyptian scorpion venom, used in research as chloride channel blocker.Fórmula:C158H256N52O48S11Pureza:98%Cor e Forma:SolidPeso molecular:4004.76Chlorotoxin
CAS:Chlorotoxin: 36-amino acid peptide from deathstalker scorpion venom; blocks small chloride channels.Fórmula:C158H249N53O47S11Pureza:98%Cor e Forma:SolidPeso molecular:3995.71D-myo-Inositol-1,4,5,6-tetraphosphate tetrasodium
D-myo-Inositol-1,4,5,6-tetraphosphate tetrasodium (Inositol 1,4,5,6-tetraphosphate tetrasodium) is one of the isomers of inositol oligophosphates. At concentrations of 8-10 μM, it almost completely inhibits calcium-activated chloride channels (chloride channels).Lubiprostone hemiketal
CAS:Lubiprostone (hemiketal) (RU-0211 (hemiketal)), a selective activator of the chloride channel 2 (CLCN2), facilitates the treatment of chronic idiopathic constipation and opioid-induced constipation. It functions by enhancing CLCN2 channel activity, which boosts chloride ion secretion in the intestines, subsequently increasing fluid secretion and improving intestinal peristalsis. Additionally, Lubiprostone (hemiketal) may be utilized in research related to chronic constipation and cancer.Fórmula:C20H32F2O5Cor e Forma:SolidPeso molecular:390.4619Afoxolaner (Standard)
CAS:Afoxolaner (Standard) is the standard substance of Afoxolaner, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.Fórmula:C26H17ClF9N3O3Cor e Forma:SolidPeso molecular:625.87
