PDE
As fosfodiesterases (PDEs) são enzimas que hidrolisam nucleotídeos cíclicos, como AMPc e GMPc, em suas formas inativas, desempenhando um papel crucial na regulação das vias de sinalização intracelular. Inibidores de PDE são utilizados no tratamento de diversas condições, incluindo doenças cardiovasculares, disfunção erétil e distúrbios respiratórios, devido à sua capacidade de modular os níveis de nucleotídeos cíclicos. Na CymitQuimica, oferecemos uma variedade de inibidores de PDE para apoiar sua pesquisa em sinalização celular, farmacologia e desenvolvimento terapêutico.
Foram encontrados 166 produtos de "PDE"
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Anti-ALDH7A1 Antibody (3P955)
<p>Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.</p>Cor e Forma:Odour LiquidAnti-ALDH7A1 Antibody (5P692)
<p>Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.</p>Cor e Forma:Odour LiquidBay 60-7550
CAS:<p>Bay 60-7550 is a PDE2 inhibitor that exerts positive inotropic effects in the rat heart by increasing PKA-mediated phosphorylation.</p>Fórmula:C27H32N4O4Pureza:98.14%Cor e Forma:SolidPeso molecular:476.57ENPP1 Inhibitor C
CAS:<p>ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.</p>Fórmula:C15H18N6Pureza:99.28%Cor e Forma:SolidPeso molecular:282.34PF-05180999
CAS:<p>α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.</p>Fórmula:C19H17F3N8Pureza:99.43% - 99.82%Cor e Forma:SolidPeso molecular:414.39Anti-ALDH7A1 Antibody (6G475)
<p>Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.</p>Cor e Forma:Odour LiquidDNMDP
CAS:DNMDP is a potent and selective PDE3A inhibitor with anticancer activity. It binds to PDE3A, promoting its interaction with Schlafen 12 (SLFN12).Fórmula:C15H20N4O3Cor e Forma:SolidPeso molecular:304.34BAY 73-6691 racemate
CAS:<p>BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.</p>Fórmula:C15H12ClF3N4OCor e Forma:SolidPeso molecular:356.73PF-05085727
CAS:<p>PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.</p>Fórmula:C20H18F3N7Pureza:98%Cor e Forma:SolidPeso molecular:413.4Crisaborole
CAS:<p>Crisaborole (AN-2728) is a Phosphodiesterase 4 Inhibitor.</p>Fórmula:C14H10BNO3Pureza:99.70%Cor e Forma:SolidPeso molecular:251.05Ensifentrine
CAS:<p>Ensifentrine (Ensifentrinum) is a PDE3/4 inhibitor, although its affinity for PDE3(IC50: 0.4 nM) is 3,440 times higher than that for PDE4(IC50: 1479 nM), that</p>Fórmula:C26H31N5O4Pureza:99.76% - 99.94%Cor e Forma:SolidPeso molecular:477.56Ibudilast
CAS:<p>Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.</p>Fórmula:C14H18N2OPureza:99.83% - >99.99%Cor e Forma:White SolidPeso molecular:230.31PQ-10
CAS:<p>PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.</p>Fórmula:C22H21N5O3Pureza:99.86%Cor e Forma:SolidPeso molecular:403.43Z-HA155
CAS:<p>Z-HA155 (CS-963) selectively and potently inhibits autotaxin with an IC50 of 5.7 nM.</p>Fórmula:C24H19BFNO5SPureza:99.18%Cor e Forma:SolidPeso molecular:463.29HA 155
CAS:<p>HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.</p>Fórmula:C24H19BFNO5SPureza:99.88%Cor e Forma:SolidPeso molecular:463.29PF-8380
CAS:<p>PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).</p>Fórmula:C22H21Cl2N3O5Pureza:98.70% - 99.25%Cor e Forma:SolidPeso molecular:478.33RS-25344 hydrochloride
CAS:<p>RS 25344 hydrochloride is a phosphodiesterase (PDE) 4 inhibitor</p>Fórmula:C19H14ClN5O4Pureza:99.25%Cor e Forma:SolidPeso molecular:411.8SEP-0372814
CAS:<p>SEP-0372814 is a potent inhibitor of PDE10.</p>Fórmula:C21H19N7Pureza:99.29%Cor e Forma:SolidPeso molecular:369.42IBMX
CAS:<p>IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 μM</p>Fórmula:C10H14N4O2Pureza:98% - >99.99%Cor e Forma:Off-WhitePeso molecular:222.24ML-030
CAS:<p>ML-030 is a potent PDE4 inhibitor, selective for subtypes (A1, B1, B2, C1, D2) with IC50 ranging from 6.7 to 452 nM.</p>Fórmula:C20H20N4O4SPureza:97.93%Cor e Forma:SolidPeso molecular:412.46
