PDE
As fosfodiesterases (PDEs) são enzimas que hidrolisam nucleotídeos cíclicos, como AMPc e GMPc, em suas formas inativas, desempenhando um papel crucial na regulação das vias de sinalização intracelular. Inibidores de PDE são utilizados no tratamento de diversas condições, incluindo doenças cardiovasculares, disfunção erétil e distúrbios respiratórios, devido à sua capacidade de modular os níveis de nucleotídeos cíclicos. Na CymitQuimica, oferecemos uma variedade de inibidores de PDE para apoiar sua pesquisa em sinalização celular, farmacologia e desenvolvimento terapêutico.
Foram encontrados 180 produtos para "PDE".
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Nerandomilast
CAS:Nerandomilast (BI 1015550) is an orally active PDE4B inhibitor with IC50 of 7.2 nM.Cost-effective and quality-assured.Fórmula:C20H25ClN6O2SPureza:98.06% - 99.96%Cor e Forma:SoildPeso molecular:448.97Theodrenaline hydrochloride
CAS:Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.Fórmula:C17H22ClN5O5Pureza:97.05% - 98.18%Cor e Forma:SolidPeso molecular:411.84N-Ethyl tadalafil
CAS:N-Ethyl tadalafil (NEthyl tadalafil) is a PDE inhibitor used in the study of cardiovascular disease.Fórmula:C23H21N3O4Pureza:99.58%Cor e Forma:SolidPeso molecular:403.43Anti-ALDH7A1 Antibody (6G475)
Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.Cor e Forma:Odour LiquidAutotaxin modulator 1
CAS:Autotaxin modulator 1 is a new modulator of Autotaxin.Fórmula:C28H31F6NO3Pureza:99.46%Cor e Forma:White SolidPeso molecular:543.54Ref: TM-T10418
1mg49,00€2mg70,00€5mg101,00€1mL*10mM (DMSO)123,00€10mg167,00€25mg313,00€50mg470,00€100mg675,00€200mg945,00€ALDH7A1 Protein, Human, Recombinant (His)
ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family.Cor e Forma:Transparent LiquidPeso molecular:56 kDa (predicted); 56 kDa (reducing conditions)Bay 60-7550
CAS:Bay 60-7550 is a PDE2 inhibitor that exerts positive inotropic effects in the rat heart by increasing PKA-mediated phosphorylation.Fórmula:C27H32N4O4Pureza:98.14%Cor e Forma:SolidPeso molecular:476.57Anti-ALDH7A1 Antibody (5P692)
Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.Cor e Forma:Odour LiquidPF-05180999
CAS:α-2,3-sialyltransferase-IN-1 (Lith-O-Asp analog) is an α-2,3-sialyltransferase inhibitor with anticancer activity.Fórmula:C19H17F3N8Pureza:99.43% - 99.82%Cor e Forma:SolidPeso molecular:414.39ENPP1 Inhibitor C
CAS:ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.Fórmula:C15H18N6Pureza:99.28%Cor e Forma:Yellow ViscousPeso molecular:282.34Ref: TM-T37431
2mg105,00€1mL*10mM (DMSO)178,00€5mg222,00€10mg356,00€25mg715,00€50mg1.134,00€100mg1.521,00€200mg2.062,00€PF-05085727
CAS:PF-05085727 inhibits PDE2A >4,000-fold selectivity over PDE1 and PDE3-11.Fórmula:C20H18F3N7Pureza:98%Cor e Forma:SolidPeso molecular:413.4BAY 73-6691 racemate
CAS:BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.Fórmula:C15H12ClF3N4OCor e Forma:White SolidPeso molecular:356.73Anti-ALDH7A1 Antibody (3P955)
Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.Cor e Forma:Odour LiquidAnti-ALDH7A1 Antibody-FITC (5P692)
Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.Cor e Forma:Odour LiquidDNMDP
CAS:DNMDP is a potent and selective PDE3A inhibitor with anticancer activity. It binds to PDE3A, promoting its interaction with Schlafen 12 (SLFN12).Fórmula:C15H20N4O3Cor e Forma:Orange SolidPeso molecular:304.34Anti-ALDH7A1 Antibody (1G435)
Anti-ALDH7A1 Antibody (1G435) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (1G435) can be used in ELISA.Cor e Forma:Odour LiquidBI-2545
CAS:BI-2545 is a potent and selective autotaxin (ATX) inhibitor with IC50 values of 2.2 nM and 3.4 nM for human and rat ATX, reduces plasma LPA levels.Fórmula:C23H19F6N5O3Pureza:98.85%Cor e Forma:White SolidPeso molecular:527.42MBCQ
CAS:MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.Fórmula:C16H12ClN3O2Pureza:99.45%Cor e Forma:SolidPeso molecular:313.74Ref: TM-T21965
5mg44,00€1mL*10mM (DMSO)50,00€10mg75,00€25mg138,00€50mg220,00€100mg318,00€200mg442,00€Cilostamide
CAS:Cilostamide (OPC3689) is a selective phosphodiesterase (PDE)3A and PDE3B inhibitor(IC50 values of 27 and 50 nM, respectively)Fórmula:C20H26N2O3Pureza:98.87%Cor e Forma:White To Off-White SolidPeso molecular:342.43PF-8380
CAS:PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).Fórmula:C22H21Cl2N3O5Pureza:98.70% - 99.25%Cor e Forma:SolidPeso molecular:478.33
