PDE
As fosfodiesterases (PDEs) são enzimas que hidrolisam nucleotídeos cíclicos, como AMPc e GMPc, em suas formas inativas, desempenhando um papel crucial na regulação das vias de sinalização intracelular. Inibidores de PDE são utilizados no tratamento de diversas condições, incluindo doenças cardiovasculares, disfunção erétil e distúrbios respiratórios, devido à sua capacidade de modular os níveis de nucleotídeos cíclicos. Na CymitQuimica, oferecemos uma variedade de inibidores de PDE para apoiar sua pesquisa em sinalização celular, farmacologia e desenvolvimento terapêutico.
Foram encontrados 166 produtos de "PDE"
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GSK256066
CAS:<p>GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold</p>Fórmula:C27H26N4O5SPureza:99.60% - 99.66%Cor e Forma:SolidPeso molecular:518.58Nortadalafil
CAS:<p>Nortadalafil, a demethylated form of Tadalafil, is a PDE5 inhibitor used to treat ED and pulmonary arterial hypertension as Adcirca.</p>Fórmula:C21H17N3O4Pureza:99.42%Cor e Forma:SolidPeso molecular:375.38Homo Sildenafil
CAS:<p>Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.</p>Fórmula:C23H32N6O4SPureza:99.88%Cor e Forma:White SolidPeso molecular:488.6GEBR-7b
CAS:<p>GEBR-7b (3-(Cyclopentyloxy)-4-methoxybenzaldehyde) is a phosphodiesterase-4 (PDE4) inhibitor.</p>Fórmula:C13H16O3Pureza:99.533%Cor e Forma:SolidPeso molecular:220.26Enoximone
CAS:<p>Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.</p>Fórmula:C12H12N2O2SPureza:98.53%Cor e Forma:SolidPeso molecular:248.3MY-5445
CAS:<p>MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5).</p>Fórmula:C20H14ClN3Pureza:99.77%Cor e Forma:SolidPeso molecular:331.8Amino Tadalafil
CAS:<p>Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.</p>Fórmula:C21H18N4O4Pureza:99.85%Cor e Forma:White PowderPeso molecular:390.39Sildenafil Mesylate
CAS:<p>Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.</p>Fórmula:C22H30N6O4S·xCH4O3SPureza:99.84%Cor e Forma:SolidPeso molecular:570.68Lodenafil
CAS:<p>Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)</p>Fórmula:C23H32N6O5SPureza:99.92%Cor e Forma:SolidPeso molecular:504.6[11C]MP 10
CAS:<p>[11C]MP 10 (PF-2545920), a specific and effective PDE10A inhibitor (IC50=0.37 nM), is with more than1000-fold specificity activity over the PDE.</p>Fórmula:C25H20N4OPureza:99.5%Cor e Forma:SolidPeso molecular:391.45Osoresnontrine
CAS:<p>Osoresnontrine is a potent and selective inhibitor of PDE9A (IC50 of 52 nM),and can be used in the research of memory.</p>Fórmula:C16H17N5O2Pureza:99.93%Cor e Forma:SolidPeso molecular:311.34CP671305
CAS:<p>CP671305 is an orally active, potent and selective inhibitor of phosphodiesterase-4-D.</p>Fórmula:C23H19FN2O7Pureza:99.39%Cor e Forma:SolidPeso molecular:454.4Ziritaxestat
CAS:<p>Ziritaxestat (GLPG1690), an autotaxin inhibitor, currently being evaluated in an exploratory phase 2 study in idiopathic pulmonary fibrosis patients.</p>Fórmula:C30H33FN8O2SPureza:97% - 99.85%Cor e Forma:SolidPeso molecular:588.7PDE10-IN-1
CAS:<p>PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.</p>Fórmula:C21H19N7Pureza:99.65%Cor e Forma:SolidPeso molecular:369.42RS-25344
CAS:<p>RS-25344: a strong PDE4 blocker, curbs eosinophil movement, boosts sperm motility in vitro.</p>Fórmula:C19H13N5O4Pureza:98.98%Cor e Forma:SolidPeso molecular:375.34Lotamilast
CAS:<p>Lotamilast (RVT-501) is a phosphodiesterase 4 (PDE-4) inhibitor (IC50: 2.8 nM) potentially for the treatment of atopic dermatitis.</p>Fórmula:C26H24N4O5Pureza:97.03% - 99.29%Cor e Forma:SolidPeso molecular:472.49Enpp-1-IN-1
CAS:<p>Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)</p>Fórmula:C17H17N3O3SPureza:97.52%Cor e Forma:SolidPeso molecular:343.4GSK256066 Trifluoroacetate
CAS:<p>GSK 256066 Trifluoroacetate: selective PDE4 inhibitor, IC50: 3.2 pM for PDE4B, treats COPD.</p>Fórmula:C29H27F3N4O7SCor e Forma:SolidPeso molecular:632.61Crisaborole-d4
<p>Crisaborole-d4 (AN-2728-d4) is the deuterated form of Crisaborole. Crisaborole is a PDE4 inhibitor and also a cytokine release inhibitor.</p>Fórmula:C14H6D4BNO3Cor e Forma:SolidPeso molecular:255.07ent-Tadalafil
CAS:<p>ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).</p>Fórmula:C22H19N3O4Pureza:98%Cor e Forma:SolidPeso molecular:389.4
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