PDE
As fosfodiesterases (PDEs) são enzimas que hidrolisam nucleotídeos cíclicos, como AMPc e GMPc, em suas formas inativas, desempenhando um papel crucial na regulação das vias de sinalização intracelular. Inibidores de PDE são utilizados no tratamento de diversas condições, incluindo doenças cardiovasculares, disfunção erétil e distúrbios respiratórios, devido à sua capacidade de modular os níveis de nucleotídeos cíclicos. Na CymitQuimica, oferecemos uma variedade de inibidores de PDE para apoiar sua pesquisa em sinalização celular, farmacologia e desenvolvimento terapêutico.
Foram encontrados 169 produtos de "PDE"
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Imazodan hydrochloride
CAS:Imazodan hydrochloride (CI-914 HCl) is a potent and selective type III phosphodiesterase inhibitor used in the treatment of chronic congestive heart failure.Fórmula:C13H13ClN4OPureza:98.97%Cor e Forma:SolidPeso molecular:276.72PAT-048
CAS:PAT-048 is an effective and selective autotaxin inhibitor.Fórmula:C22H18ClF2N3O2SPureza:98%Cor e Forma:SolidPeso molecular:461.91BAY 73-6691
CAS:BAY 73-6691 is an inhibitor of brain penetrant PDE9A.Fórmula:C15H12ClF3N4OCor e Forma:SolidPeso molecular:356.73Verofylline
CAS:Verofylline (Verofyllinum) is an orally available, long-acting, multiacting, methylxanthine-substituted bronchodilator with inhibitory effects on PDE4 for theFórmula:C12H18N4O2Pureza:98.4% - 99.8%Cor e Forma:SolidPeso molecular:250.3Nanterinone
CAS:Nanterinone: oral phosphodiesterase inhibitor, improves acute heart failure hemodynamics.Fórmula:C15H15N3OPureza:99.96%Cor e Forma:SolidPeso molecular:253.3PF-04447943
CAS:PF-04447943, a selective PDE9A inhibitor (IC50=12nM), may aid sickle cell anemia research with its anti-inflammatory properties.Fórmula:C20H25N7O2Pureza:97.01% - 99.36%Cor e Forma:SolidPeso molecular:395.46Isomazole
CAS:Isomazole is a novel orally available phosphodiesterase (PDE) inhibitor with calcium-sensitizing properties that inhibits PDE3 and PDE4.
Fórmula:C14H13N3O2SPureza:98.66%Cor e Forma:SolidPeso molecular:287.34Dovramilast
CAS:Dovramilast (CC-11050) is a PDE4 inhibitor that reduces the production of pro-inflammatory mediators in lupus erythematosus.Fórmula:C24H28N2O6SPureza:98.75% - 99.62%Cor e Forma:SolidPeso molecular:472.55MK-0873
CAS:MK-0873 is a novel and potent selective phosphodiesterase 4 (PDE4) inhibitor.Fórmula:C25H18N4O3Pureza:99.14%Cor e Forma:SolidPeso molecular:422.44Dasantafil
CAS:Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.Fórmula:C22H28BrN5O5Pureza:99.4% - 99.50%Cor e Forma:SolidPeso molecular:522.39PDE IV-IN-1
CAS:PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary diseaseFórmula:C20H23ClN4O2Pureza:99.79%Cor e Forma:SolidPeso molecular:386.88Ref: TM-T10201
1mg225,00€5mg480,00€1mL*10mM (DMSO)540,00€10mg642,00€25mg964,00€50mg1.288,00€100mg1.738,00€200mg2.332,00€Carbazeran
CAS:Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases.Fórmula:C18H24N4O4Pureza:99.3%Cor e Forma:SolidPeso molecular:360.41Ref: TM-T21457
1mL*10mM (DMSO)A consultar2mg42,00€5mg62,00€10mg96,00€25mg170,00€50mg256,00€100mg385,00€Autotaxin-IN-3
CAS:Autotaxin-IN-3 is an inhibitor of Autotaxin (IC50 = 2.4 nM) which is responsible for the increase in lysophosphatidic acid in ascites and plasma.Fórmula:C22H21N9O2Pureza:99.54% - 99.79%Cor e Forma:SolidPeso molecular:443.46Ref: TM-T10415
2mg43,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg96,00€25mg173,00€50mg269,00€100mg432,00€200mg592,00€Filaminast
CAS:Filaminast (UNII-CDD69JC61J) is an analog of a phosphodiesterase 4 inhibitor (PDE4 inhibitor) and roliplam, which is used as an anti-asthma drug.Fórmula:C15H20N2O4Pureza:98.93% - 99.99%Cor e Forma:SolidPeso molecular:292.33Ref: TM-T31792
1mg156,00€1mL*10mM (DMSO)333,00€5mg366,00€10mg487,00€25mg737,00€50mg982,00€100mg1.324,00€200mg1.791,00€uk-50001
CAS:UK-50001 is a PDE4 inhibitor for treating inflammation, allergies, respiratory issues, and wounds.Fórmula:C26H24F3N3O4Pureza:99.90%Cor e Forma:SolidPeso molecular:499.48Ref: TM-T67815
1mg150,00€5mg360,00€1mL*10mM (DMSO)445,00€10mg540,00€25mg863,00€50mg1.153,00€100mg1.575,00€500mg3.142,00€Mopidamol
CAS:Mopidamol (RA 233) is a phosphodiesterase inhibitor, a dipyridamole derivative, with anticancer activity that prevents retinal vascular defects in experimentalFórmula:C19H31N7O4Pureza:99.31% - 99.78%Cor e Forma:SolidPeso molecular:421.49PDE4B-IN-2
CAS:PDE4B-IN-2 (A 33), an oral PDE4B inhibitor, IC50: 15 nM; less potent on PDE4D (IC50: 1.7 µM), has anti-inflammatory properties.Fórmula:C19H18ClN3O2SPureza:99.32%Cor e Forma:SolidPeso molecular:387.88Ref: TM-T36832
1mg37,00€5mg79,00€1mL*10mM (DMSO)87,00€10mg111,00€25mg216,00€50mg354,00€100mg567,00€500mg1.198,00€AWD 12-281
CAS:AWD 12-281 is a PDE4 inhibitor with anti-inflammatory activity and bronchodilator activity for the study of chronic obstructive pulmonary disease (COPD).Fórmula:C22H14Cl2FN3O3Pureza:99.25% - 99.85%Cor e Forma:SolidPeso molecular:458.27Tofimilast
CAS:Tofimilast (CP-325366), a PDE4 inhibitor, is used potentially for the treatment of asthma and chronic obstructive pulmonary disease.Fórmula:C18H21N5SPureza:99.55%Cor e Forma:SolidPeso molecular:339.46Adibendan
CAS:Adibendan (Adibendanum) is a selective inhibitor of PDE3 with an IC50 of 2.0 μM.Fórmula:C16H14N4OPureza:99.52% - >99.99%Cor e Forma:SolidPeso molecular:278.31
