Glucoquinase
A glucocinase (GK) é uma enzima que catalisa a fosforilação da glicose em glicose-6-fosfato, um passo crítico na glicólise. A GK é predominantemente expressa no fígado e no pâncreas, onde desempenha um papel fundamental na regulação dos níveis de glicose no sangue. Inibidores de GK são de grande interesse no estudo de distúrbios metabólicos como o diabetes, pois podem modular o metabolismo da glicose e a secreção de insulina. Na CymitQuimica, oferecemos inibidores de glucocinase para apoiar sua pesquisa em diabetes, metabolismo e desenvolvimento terapêutico.
Foram encontrados 53 produtos de "Glucoquinase"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Dorzagliatin
CAS:<p>Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.</p>Fórmula:C22H27ClN4O5Pureza:98.67% - 99.45%Cor e Forma:SolidPeso molecular:462.93MitoPQ
CAS:<p>MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.</p>Fórmula:C39H46I3N2PPureza:99.91% - ≥98%Cor e Forma:SolidPeso molecular:954.48WAY-640509
CAS:<p>WAY-640509 is a glucocerebrosidase inhibitor.</p>Fórmula:C25H23N5O4SPureza:99.36%Cor e Forma:SolidPeso molecular:489.55MK-0941 free base
CAS:<p>MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.</p>Fórmula:C21H24N4O6SPureza:98.75%Cor e Forma:SolidPeso molecular:460.5Oxfendazole
CAS:<p>Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.</p>Fórmula:C15H13N3O3SPureza:98.99% - 99.17%Cor e Forma:White To Yellowish PowderPeso molecular:315.35KAN0438757
CAS:<p>KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.</p>Fórmula:C21H18FNO7SPureza:99.34%Cor e Forma:SolidPeso molecular:447.43ADP-specific glucokinase
CAS:<p>ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.</p>Cor e Forma:Solid(1S,2R)-Globalagliatin
CAS:<p>(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.</p>Fórmula:C28H37N3O3S3Pureza:99.09% - >99.99%Cor e Forma:SoildPeso molecular:559.81ML266
CAS:<p>ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.</p>Fórmula:C24H22BrN3O4Pureza:99.58%Cor e Forma:SolidPeso molecular:496.35ML251
CAS:<p>ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.</p>Fórmula:C17H13Cl2N3O4SPureza:99.87%Cor e Forma:SolidPeso molecular:426.27AP-III-a4 hydrochloride
CAS:<p>AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.</p>Fórmula:C31H44ClFN8O3Pureza:98%Cor e Forma:SolidPeso molecular:631.18Glucokinase Protein, Human, Recombinant
<p>Glucokinase belongs to the bacterial glucokinase family.</p>Cor e Forma:Lyophilized PowderPeso molecular:52.2 kDa (predicted); 52.2 kDa (reducing conditions)Cadisegliatin
CAS:<p>Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.</p>Fórmula:C21H33N3O4S2Cor e Forma:SolidPeso molecular:455.63Anti-Glucokinase Antibody (5Q209)
<p>Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.</p>Cor e Forma:Odour LiquidAnti-Glucokinase Antibody (3U461)
<p>Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.</p>Cor e Forma:Odour Liquid5MPN
CAS:<p>5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.</p>Fórmula:C15H19N3O4Pureza:98.92% - 99.69%Cor e Forma:SolidPeso molecular:305.33PF-04991532
CAS:<p>PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.</p>Fórmula:C18H19F3N4O3Pureza:99.99%Cor e Forma:SolidPeso molecular:396.36PFK-015
CAS:<p>PFK-015 (PFK15) is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).</p>Fórmula:C17H12N2OPureza:99.7% - 99.85%Cor e Forma:SolidPeso molecular:260.29Globalagliatin
CAS:<p>Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2.</p>Fórmula:C28H37N3O3S3Pureza:98% - 99.49%Cor e Forma:SolidPeso molecular:559.81(E)-3PO
CAS:<p>(E)-3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase) inhibitor.</p>Fórmula:C13H10N2OPureza:98.8% - 98.92%Cor e Forma:SolidPeso molecular:210.23
