Glucoquinase
A glucocinase (GK) é uma enzima que catalisa a fosforilação da glicose em glicose-6-fosfato, um passo crítico na glicólise. A GK é predominantemente expressa no fígado e no pâncreas, onde desempenha um papel fundamental na regulação dos níveis de glicose no sangue. Inibidores de GK são de grande interesse no estudo de distúrbios metabólicos como o diabetes, pois podem modular o metabolismo da glicose e a secreção de insulina. Na CymitQuimica, oferecemos inibidores de glucocinase para apoiar sua pesquisa em diabetes, metabolismo e desenvolvimento terapêutico.
Foram encontrados 57 produtos de "Glucoquinase"
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MK-0941 free base
CAS:MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.Fórmula:C21H24N4O6SPureza:98.75%Cor e Forma:SolidPeso molecular:460.5Ref: TM-T12056
1mg87,00€5mg172,00€10mg258,00€25mg425,00€50mg598,00€100mg810,00€1mL*10mM (DMSO)208,00€Dorzagliatin
CAS:Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.Fórmula:C22H27ClN4O5Pureza:98.67% - 99.45%Cor e Forma:SolidPeso molecular:462.93Ref: TM-T15159
1mg38,00€2mg50,00€5mg82,00€10mg116,00€25mg227,00€50mg358,00€100mg537,00€1mL*10mM (DMSO)90,00€Oxfendazole
CAS:Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.Fórmula:C15H13N3O3SPureza:98.99% - 99.17%Cor e Forma:White To Yellowish PowderPeso molecular:315.35WAY-640509
CAS:WAY-640509 is a glucocerebrosidase inhibitor.Fórmula:C25H23N5O4SPureza:99.36%Cor e Forma:SolidPeso molecular:489.55Ref: TM-T60048
1mg115,00€2mg172,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.157,00€MitoPQ
CAS:MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.Fórmula:C39H46I3N2PPureza:99.87% - 99.91%Cor e Forma:SolidPeso molecular:954.48KAN0438757
CAS:KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
Fórmula:C21H18FNO7SPureza:99.34%Cor e Forma:SolidPeso molecular:447.43ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Fórmula:C17H13Cl2N3O4SPureza:99.87%Cor e Forma:SolidPeso molecular:426.27Ref: TM-T64320
1mg115,00€5mg274,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€200mg1.825,00€1mL*10mM (DMSO)301,00€WAY-615145
CAS:WAY-615145 is a compound that activates glucokinase.Fórmula:C16H18N2OSCor e Forma:SolidPeso molecular:286.39ML266
CAS:ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.Fórmula:C24H22BrN3O4Pureza:99.58%Cor e Forma:SolidPeso molecular:496.35Ref: TM-T8990
1mg50,00€2mg71,00€5mg105,00€10mg166,00€25mg325,00€50mg449,00€100mg652,00€500mg1.369,00€1mL*10mM (DMSO)114,00€AP-III-a4 hydrochloride
CAS:AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.Fórmula:C31H44ClFN8O3Pureza:98%Cor e Forma:SolidPeso molecular:631.18Ref: TM-T6759L
2mg97,00€5mg178,00€10mg286,00€25mg588,00€50mg830,00€100mgA consultar200mgA consultar1mL*10mM (DMSO)248,00€ADP-specific glucokinase
CAS:ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.Cor e Forma:SolidNeuron-specific enolase, Human
Neuron-specific enolase, Human (EC 4.2.1.11), is an enolase enzyme that serves as a biomarker for traumatic brain injury (TBI), stroke following cardiac arrest, hypoxic encephalopathy, and acute spinal cord injury (SCI).Cor e Forma:Odour Solid(1S,2R)-Globalagliatin
CAS:(1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.Fórmula:C28H37N3O3S3Pureza:99.09% - 99.17%Cor e Forma:SoildPeso molecular:559.81PF-04991532
CAS:PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.Fórmula:C18H19F3N4O3Pureza:99.99%Cor e Forma:SolidPeso molecular:396.36Cadisegliatin
CAS:Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.Fórmula:C21H33N3O4S2Cor e Forma:SolidPeso molecular:455.63Anti-Glucokinase Antibody (3U461)
Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.Cor e Forma:Odour Liquid5MPN
CAS:5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.Fórmula:C15H19N3O4Pureza:98.92% - 99.69%Cor e Forma:SolidPeso molecular:305.33Ref: TM-T40565
2mg92,00€5mg160,00€10mg260,00€25mg522,00€50mg835,00€100mg1.341,00€200mg1.773,00€1mL*10mM (DMSO)170,00€Anti-Glucokinase Antibody (5Q209)
Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.Cor e Forma:Odour LiquidHex
CAS:Hex is a potent inhibitor of enolase, exhibiting inhibitory activity with Ki values of 74.4 nM and 269.4 nM against ENO2 and ENO1, respectively.Fórmula:C5H10NO5PCor e Forma:SolidPeso molecular:195.11Glucokinase Protein, Human, Recombinant
Glucokinase belongs to the bacterial glucokinase family.Cor e Forma:Lyophilized PowderPeso molecular:52.2 kDa (predicted); 52.2 kDa (reducing conditions)
