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Glucoquinase

Glucoquinase

A glucocinase (GK) é uma enzima que catalisa a fosforilação da glicose em glicose-6-fosfato, um passo crítico na glicólise. A GK é predominantemente expressa no fígado e no pâncreas, onde desempenha um papel fundamental na regulação dos níveis de glicose no sangue. Inibidores de GK são de grande interesse no estudo de distúrbios metabólicos como o diabetes, pois podem modular o metabolismo da glicose e a secreção de insulina. Na CymitQuimica, oferecemos inibidores de glucocinase para apoiar sua pesquisa em diabetes, metabolismo e desenvolvimento terapêutico.

Foram encontrados 55 produtos para "Glucoquinase".

produtos por página.
  • WAY-640509

    CAS:
    WAY-640509 is a glucocerebrosidase inhibitor.
    Fórmula:C25H23N5O4S
    Pureza:99.36%
    Cor e Forma:Solid
    Peso molecular:489.546
  • MitoPQ

    CAS:
    MitoPQ (MitoParaquat) inhibits insulin-stimulated glucose uptake and plasma membrane translocation in myotubes and can be used to study oxidative stress.
    Fórmula:C39H46I3N2P
    Pureza:99.87% - 99.91%
    Cor e Forma:Red Solid
    Peso molecular:954.48
  • Oxfendazole

    CAS:
    Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.
    Fórmula:C15H13N3O3S
    Pureza:98.99% - 99.17%
    Cor e Forma:Solid
    Peso molecular:315.35
  • Dorzagliatin

    CAS:
    Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.
    Fórmula:C22H27ClN4O5
    Pureza:98.67% - 99.45%
    Cor e Forma:Solid
    Peso molecular:462.927
  • MK-0941 free base

    CAS:
    MK-0941: an oral glucokinase activator for type 2 diabetes with potent glucose-lowering effects.
    Fórmula:C21H24N4O6S
    Pureza:98.75%
    Cor e Forma:Solid
    Peso molecular:460.503
  • ML251

    CAS:
    ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.
    Fórmula:C17H13Cl2N3O4S
    Pureza:99.87%
    Cor e Forma:Solid
    Peso molecular:426.274
  • ML266

    CAS:
    ML266: GCase chaperone, non-inhibiting, IC50=2.5 µM, aids mutant protein transport, may help in Gaucher disease study.
    Fórmula:C24H22BrN3O4
    Pureza:99.58%
    Cor e Forma:White Solid
    Peso molecular:496.353
  • PFKFB3-IN-2

    CAS:
    PFKFB3-IN-2 is a 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3) inhibitor.
    Fórmula:C14H11NO7S
    Pureza:99.15%
    Cor e Forma:Solid
    Peso molecular:337.305
  • RO-28-1675

    CAS:
    RO-28-1675 is a direct and selective glucokinase activator, the GK/GKRP complex,insulin secretion and type 2 diabetes.
    Fórmula:C18H22N2O3S2
    Pureza:98.13%
    Cor e Forma:Solid
    Peso molecular:378.509
  • Glucokinase

    CAS:
    Glucokinase is a biochemical reagent used as a biomaterial or organic compound for research in the life sciences.
  • ADP-specific glucokinase

    CAS:
    ADP-specific glucokinase, expressed in thermophilic archaea, is an ADP-specific enzyme that catalyzes the conversion of glucose to glucose-6-phosphate, thereby facilitating glycolysis. This enzyme can activate T cells and enhance the phagocytic activity of macrophages. It is used in research related to metabolic disorders, neurological diseases, and tumors.
    Cor e Forma:Solid
  • AP-III-a4 hydrochloride

    CAS:
    AP-III-a4 hydrochloride (ENOblock hydrochloride) is a direct enolase (enolase) inhibitor that inhibit metastasis and affect glucose homeostasis.
    Fórmula:C31H44ClFN8O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:631.184
  • (1S,2R)-Globalagliatin

    CAS:
    (1S,2R)-Globalagliatin is a highly potent glucokinase (GK) activator for the study of type 2 diabetes.
    Fórmula:C28H37N3O3S3
    Pureza:99.05% - 99.17%
    Cor e Forma:Solid
    Peso molecular:559.81
  • 5MPN

    CAS:
    5MPN is a PFKFB4 inhibitor that inhibits the F6P binding site and suppresses the proliferation of myeloma cells.
    Fórmula:C15H19N3O4
    Pureza:98.92% - 99.69%
    Cor e Forma:Solid
    Peso molecular:305.3291
  • PF-04991532

    CAS:
    PF-04991532 is a hepatoselective glucokinase activator that reduces plasma glucose and AMP concentrations in the Goto-Kakizaki rat model.
    Fórmula:C18H19F3N4O3
    Pureza:99.99%
    Cor e Forma:White Solid
    Peso molecular:396.3637
  • Anti-Glucokinase Antibody (3U461)


    Anti-Glucokinase Antibody (3U461) is a Rabbit antibody targeting Glucokinase. Anti-Glucokinase Antibody (3U461) can be used in ELISA.
    Cor e Forma:Odour Liquid
  • Anti-Glucokinase Antibody (5Q209)


    Anti-Glucokinase Antibody (5Q209) is a Mouse antibody targeting Glucokinase. Anti-Glucokinase Antibody (5Q209) can be used in ELISA.
    Cor e Forma:Odour Liquid
  • Hex

    CAS:
    Hex is an enolase inhibitor and antimalarial agent with antitumor effects on intracranial tumors.
    Fórmula:C5H10NO5P
    Cor e Forma:Brown Solid
    Peso molecular:195.11
  • Cadisegliatin

    CAS:
    Cadisegliatin (TTP-399) may activate liver GK to lower blood sugar in type 2 diabetes studies.
    Fórmula:C21H33N3O4S2
    Cor e Forma:Solid
    Peso molecular:455.634
  • Glucokinase Protein, Human, Recombinant


    Glucokinase belongs to the bacterial glucokinase family.
    Cor e Forma:Lyophilized Powder
    Peso molecular:52.2 kDa (predicted); 52.2 kDa (reducing conditions)