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Factor Xa

Factor Xa

O fator Xa é uma enzima crucial na cascata de coagulação que converte a protrombina em trombina, levando à formação de coágulos sanguíneos. A inibição do fator Xa é uma estratégia terapêutica amplamente utilizada para prevenir e tratar distúrbios tromboembólicos, como trombose venosa profunda, embolia pulmonar e AVC. Na CymitQuimica, oferecemos inibidores do fator Xa para apoiar sua pesquisa em hematologia, saúde cardiovascular e terapia anticoagulante.

Foram encontrados 80 produtos de "Factor Xa"

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  • Rivaroxaban

    CAS:
    <p>Rivaroxaban (BAY 59-7939) is an oral, direct factor Xa inhibitor with anticoagulant properties, interfering with thrombin formation.</p>
    Fórmula:C19H18ClN3O5S
    Pureza:99.93% - >99.99%
    Cor e Forma:Solid
    Peso molecular:435.88
  • Gabexate mesylate

    CAS:
    <p>Gabexate mesylate (FOY) inhibits thrombin, plasmin, kallikrein; used for pancreatitis, DIC, hemodialysis anticoagulant.</p>
    Fórmula:C17H27N3O7S
    Pureza:99.2% - 99.64%
    Cor e Forma:White Crystal
    Peso molecular:417.48
  • Letaxaban

    CAS:
    <p>Letaxaban (TAK-442) is a small molecule Xa factor inhibitor that can be used to study polar coronary syndromes and thrombotic blockages.</p>
    Fórmula:C22H26ClN3O5S
    Pureza:99.13% - 99.87%
    Cor e Forma:Solid
    Peso molecular:479.98
  • 5-R-Rivaroxaban

    CAS:
    <p>5-R-Rivaroxaban is the (R)-enantiomer of Rivaroxaban, a potent FXa inhibitor with IC50 0.7 nM and Ki 0.4 nM.</p>
    Fórmula:C19H18ClN3O5S
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:435.88
  • Osocimab

    CAS:
    <p>Osocimab (BAY 1213790) is a strong FXIa inhibitor, Ki 2.4 nM, EC50 0.2 nM, and reduces thrombosis in research.</p>
    Pureza:> 95% - > 95%
    Cor e Forma:Liquid
    Peso molecular:144.46 kDa
  • 2-Methoxyphenothiazine

    CAS:
    <p>2-Methoxy Phenothiazine is light yellow or light gray solid.</p>
    Fórmula:C13H11NOS
    Pureza:99.28%
    Cor e Forma:Orange Yellow Crystal Powder
    Peso molecular:229.3
  • Ciraparantag acetate

    CAS:
    <p>Ciraparantag acetate reverses anticoagulation, binding heparins and DOACs noncovalently.</p>
    Fórmula:C24H52N12O4
    Pureza:99.65%
    Cor e Forma:Solid
    Peso molecular:572.75
  • Garadacimab

    CAS:
    <p>Garadacimab (CSL312) is a human IgG4 antibody against FXIIa, used to research hereditary angioedema.</p>
    Pureza:SDS-PAGE:95% SEC-HPLC:99.99%
    Cor e Forma:Liquid
    Peso molecular:146.5 kDa
  • Canine Factor Xa


    <p>CanineFactor Xa is derived from purified Canine Factor X through activation by Russell's Viper Venom, after which the venom is removed.</p>
    Cor e Forma:Odour Solid
  • D-Pro-Phe-Arg-Chloromethylketone

    CAS:
    <p>D-Pro-Phe-Arg-Chloromethylketone, an inhibitor of coagulation factor XII and plasma kallikrein, is significant in the regulation of thrombosis and inflammation</p>
    Fórmula:C21H31ClN6O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:450.96
  • FXIa-IN-15

    CAS:
    <p>FXIa-IN-15 (Compound (S)-10h) is an inhibitor of factor XIa (FXIa) and plasma kallikrein (PKa) with IC50 values of 0.38 nM and 59.2 nM, respectively. It exhibits anticoagulant properties by prolonging the 50% activated partial thromboplastin time (aPTT) with an EC1.5X of 0.55 μM.</p>
    Fórmula:C32H23ClF3N7O4
    Cor e Forma:Solid
    Peso molecular:662.02
  • CH3OCO-D-CHA-Gly-Arg-pNA acetate

    CAS:
    <p>CH3OCO-D-CHA-Gly-Arg-pNA acetate serves as a chromogenic substrate for Factor Xa, as documented in sources [1] [2].</p>
    Fórmula:C27H42N8O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:622.67
  • O-Desmethyl apixaban sulfate sodium


    <p>O-Desmethyl apixaban sulfate sodium inhibits factor X (FXa) with a Ki of 58 μM,and is a major circulating metabolite of Apixaban in humans.</p>
    Fórmula:C24H22N5NaO7S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:547.52
  • Edoxaban Isomer

    CAS:
    <p>Edoxaban Isomer is an impurity of Edoxaban, which is a novel inhibitor of factor Xa.</p>
    Fórmula:C24H30ClN7O4S
    Cor e Forma:Solid
    Peso molecular:548.06
  • FXIIa-IN-1 HCl

    CAS:
    <p>FXIIa-IN-1 HCl is a selective inhibitor of Factor XIIa,and can be used to study thrombosis and inflammation induced by artificial surfaces.</p>
    Fórmula:C21H17ClN2O6
    Pureza:99.61%
    Cor e Forma:Soild
    Peso molecular:428.82
  • Boc-Ile-Glu-Gly-Arg-AMC

    CAS:
    <p>Boc-IEGR-AMC: fluorogenic substrate for factor Xa and Halocynthia roretzi acrosin.</p>
    Fórmula:C34H50N8O10
    Pureza:98%
    Cor e Forma:White Powder
    Peso molecular:730.81
  • Edoxaban impurity 6

    CAS:
    <p>Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.</p>
    Fórmula:C16H22ClN5O3
    Cor e Forma:Solid
    Peso molecular:367.83
  • Lofacimig


    <p>Lofacimig is a bispecific antibody of VH-VH-G1(h-CH2-CH3) dimer type that targets FXI/PTA.</p>
    Cor e Forma:Odour Liquid
  • Rabbit Factor Xa


    <p>RabbitFactor Xa is produced from purified Rabbit Factor X through activation by Russells' Viper Venom, followed by the removal of the venom.</p>
    Cor e Forma:Odour Solid
  • Methoxycarbonyl-D-Nle-Gly-Arg-pNA

    CAS:
    <p>Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin substrate utilized for coagulation factors IXa (FIXa) and Xa (FXa), as evidenced by studies [1] [2] [3</p>
    Fórmula:C22H34N8O7
    Cor e Forma:Solid
    Peso molecular:522.55
  • cMCoFx1

    CAS:
    <p>cMCoFx1 is an effective and selective FXIIa cyclic peptide inhibitor. It exhibits high binding affinity for FXIIa (KD: 900 pM) and potent inhibitory activity (Ki: 370 pM). cMCoFx1 effectively suppresses the intrinsic coagulation pathway, demonstrates high stability in serum, and shows no cytotoxicity.</p>
    Fórmula:C146H232N52O44S6
    Cor e Forma:Solid
    Peso molecular:3612.12
  • Naroparcil

    CAS:
    <p>Naroparcil, an oral thioglycoside, has antithrombotic properties and alters thrombin complex formation.</p>
    Fórmula:C19H17NO4S2
    Pureza:98.71% - 99.88%
    Cor e Forma:Solid
    Peso molecular:387.47
  • FXIIa-IN-4


    <p>FXIIa-IN-4 (compound 22) is a potent and selective human FXIIa inhibitor, exhibiting IC50 values of 0.032 μM for FXIIa, 0.30 μM for thrombin, and &gt;50 μM for FXIa. It is utilized in anticoagulant research.</p>
    Fórmula:C11H9FN4O3
    Peso molecular:264.06587
  • Concizumab

    CAS:
    <p>Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the</p>
    Pureza:> 95%
    Cor e Forma:Liquid
    Peso molecular:145.76 kDa
  • Asundexian

    CAS:
    <p>Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,</p>
    Fórmula:C26H21ClF4N6O4
    Pureza:99.89% - 99.90%
    Cor e Forma:Solid
    Peso molecular:592.93
  • Rat Factor Xa


    <p>RatFactor Xa is derived from the activation of purified Rat Factor X using Russells' Viper Venom. Following activation, Russells' Viper Venom is removed.</p>
    Cor e Forma:Odour Solid
  • Porcine Factor Xa

    CAS:
    <p>PorcineFactor Xa is obtained by activating purified Porcine Factor X using Russells' Viper Venom, after which the venom is removed.</p>
    Cor e Forma:Solid
  • Apixaban 13C,d3

    CAS:
    <p>Apixaban 13C,d3 is a deuterium labeling of Apixaban for isotopic tracing. Apixaban 13C,d3 is a selective inhibitor of coagulation factor Xa</p>
    Fórmula:C25H25N5O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:463.51
  • Betrixaban-d6

    CAS:
    <p>Betrixaban D6 is a deuterium-labeled Betrixaban. Betrixaban is a selective and orally efficacious FXa inhibitor.</p>
    Fórmula:C23H22ClN5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:457.95
  • Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

    CAS:
    <p>Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl) compound inhibits coagulation factor Xa, useful for thrombotic conditions study.</p>
    Fórmula:C27H28N4O5
    Pureza:99.5%
    Cor e Forma:Solid
    Peso molecular:488.54
  • Enoxaparin sodium

    CAS:
    <p>Enoxaparin, a low-weight heparin approved by FDA for STEMI, enhances antithrombin and prevents clotting by inhibiting factors XIa, IXa, Xa, IIa.</p>
    Fórmula:C42H59N3Na4O35S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1322
  • Apixaban

    CAS:
    <p>Apixaban (BMS-562247-01) is an orally active inhibitor of coagulation factor Xa with anticoagulant activity.</p>
    Fórmula:C25H25N5O4
    Pureza:99.73% - 99.93%
    Cor e Forma:Solid
    Peso molecular:459.5
  • Edoxaban Tosylate Monohydrate

    CAS:
    <p>Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.</p>
    Fórmula:C31H40ClN7O8S2
    Pureza:99.86% - 99.91%
    Cor e Forma:Solid
    Peso molecular:738.27
  • BISMUTH SUBGALLATE

    CAS:
    <p>Bismuth subgallate (Dermatol Puder) is an astringent and antiseptic and is applied to skin diseases such as eczema.</p>
    Fórmula:C7H5BiO6
    Pureza:98.7%
    Cor e Forma:White To Yellow Crystals
    Peso molecular:394.09
  • Benzamidine hydrochloride

    CAS:
    <p>Benzamidine hydrochloride (Benzamidine HCl) is a reversible inhibitor of serine proteases, including trypsin, plasmin, and thrombin.</p>
    Fórmula:C7H9ClN2
    Pureza:99.25% - 99.97%
    Cor e Forma:White To Off-White Powder
    Peso molecular:156.61
  • 4-Chlorophenylurea

    CAS:
    <p>4-Chlorophenylurea (NSC-12971) is a novel orally bioavailable inhibitor of factor Xa.</p>
    Fórmula:C7H7ClN2O
    Pureza:98.87%
    Cor e Forma:White Granular / Prill
    Peso molecular:170.6
  • Darexaban

    CAS:
    <p>Darexaban (YM-150) selectively inhibits Factor Xa, reducing clotting and risk of heart/stroke events.</p>
    Fórmula:C27H30N4O4
    Pureza:98.33%
    Cor e Forma:Solid
    Peso molecular:474.55
  • Fondaparinux sodium

    CAS:
    <p>Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.</p>
    Fórmula:C31H43N3Na10O49S8
    Pureza:98% - >99.99%
    Cor e Forma:Solid
    Peso molecular:1728.08
  • Edoxaban hydrochloride

    CAS:
    <p>Edoxaban (DU-176b) HCl: Oral, selective Factor Xa inhibitor, Ki 0.561 nM; prevents thromboembolic disease.</p>
    Fórmula:C24H31Cl2N7O4S
    Cor e Forma:Solid
    Peso molecular:584.52
  • Betrixaban hydrochloride(330942-05-7(free base))


    <p>Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) is a potent, selective, and orally efficacious factor Xa (fXa) inhibitor (IC50: 1.5</p>
    Fórmula:C23H23Cl2N5O3
    Pureza:99.54%
    Cor e Forma:Solid
    Peso molecular:488.36
  • Heparin sodium salt

    CAS:
    <p>Heparin sodium, a sulfated glycosaminoglycan, acts as an anticoagulant and inhibits exosome-cell interactions.</p>
    Fórmula:C26H42N2NaO37S5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1157.89
  • Abelacimab

    CAS:
    <p>NI-0801 (Anti-CXCL10 / IP-1) is a CHO-expressed humanized monoclonal antibody targeting CXCL10/IP-10 for the study of vitiligo and biliary cirrhosis.</p>
    Pureza:94.9% (SDS-PAGE); 99.1% (SEC-HPLC) - 94.9% (SDS-PAGE); 99.1% (SEC-HPLC)
    Cor e Forma:Liquid
  • Edoxaban-d6

    CAS:
    <p>Edoxaban-d6 is a deuterated compound of Edoxaban. Edoxaban has a CAS number of 480449-70-5. Edoxaban(DU-176) is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention.</p>
    Fórmula:C24H24D6ClN7O4S
    Cor e Forma:Solid
    Peso molecular:554.09
  • Betrixaban maleate

    CAS:
    <p>"Betrixaban, a non-vitamin K anticoagulant by Portola, inhibits factor Xa with low hERG affinity, preventing VTE in at-risk adults."</p>
    Fórmula:C27H26ClN5O7
    Pureza:99.46% - 99.86%
    Cor e Forma:Solid
    Peso molecular:567.98
  • Rivaroxaban-d4

    CAS:
    <p>Rivaroxaban-d4 is a deuterated marker of Rivaroxaban for isotopic tracing.BAY 59-7939 is a potent and selective direct inhibitor of coagulation factor Xa (FXa.</p>
    Fórmula:C19H18ClN3O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:439.91
  • Betrixaban

    CAS:
    <p>Betrixaban is a non-VKORC1 anticoagulant targeting factor Xa, with low hERG affinity, used to prevent VTE in adults with mobility issues.</p>
    Fórmula:C23H22ClN5O3
    Pureza:99.33%
    Cor e Forma:Solid
    Peso molecular:451.91
  • Milvexian

    CAS:
    <p>Milvexian (BMS-986177) is an oral antithrombotic, reversibly inhibiting human/rabbit FXIa with K i of 0.11/0.38 nM.</p>
    Fórmula:C28H23Cl2F2N9O2
    Cor e Forma:Solid
    Peso molecular:626.45
  • YM-75466

    CAS:
    <p>YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.</p>
    Fórmula:C28H35N5O8S2
    Cor e Forma:Solid
    Peso molecular:633.74
  • Pegnivacogin

    CAS:
    <p>Pegnivacogin is a coagulation factor IXa RNA aptamer inhibitor.</p>
    Fórmula:C20H40N3O11P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:529.52
  • BMS 740808

    CAS:
    <p>BMS-740808 is a highly effective and selective factor X inhibitor.</p>
    Fórmula:C31H27F3N6O3
    Cor e Forma:Solid
    Peso molecular:588.58