PPAR
Os receptores ativados por proliferadores de peroxissomas (PPARs) são um grupo de proteínas receptoras nucleares que funcionam como fatores de transcrição, regulando a expressão de genes envolvidos no metabolismo, particularmente no armazenamento de ácidos graxos e no metabolismo da glicose. Inibidores de PPAR são ferramentas importantes para o estudo de distúrbios metabólicos como diabetes, obesidade e doenças cardiovasculares. Esses inibidores podem modular o metabolismo lipídico, a sensibilidade à insulina e a inflamação, tornando-os valiosos na pesquisa terapêutica. Na CymitQuimica, oferecemos uma gama de inibidores de PPAR para apoiar sua pesquisa em doenças metabólicas, endocrinologia e desenvolvimento de medicamentos.
Foram encontrados 164 produtos de "PPAR"
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Choline Fenofibrate
CAS:<p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>Fórmula:C22H28ClNO5Pureza:98.82%Cor e Forma:SolidPeso molecular:421.91Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Cor e Forma:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84SR 16832
CAS:<p>SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.</p>Fórmula:C17H12ClN3O4Pureza:99.6%Cor e Forma:SolidPeso molecular:357.75BMS-687453
CAS:<p>BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma</p>Fórmula:C22H21ClN2O6Pureza:99.4%Cor e Forma:SolidPeso molecular:444.86NSC-87877 disodium
CAS:<p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>Fórmula:C19H13N3O7S2·2NaPureza:97.89%Cor e Forma:SolidPeso molecular:503.42Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Fórmula:C16H30O2Pureza:99.76%Cor e Forma:SolidPeso molecular:254.41Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Fórmula:C20H18O11Pureza:97.02% - 99.94%Cor e Forma:White PowderPeso molecular:434.35GW6471
CAS:<p>GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.</p>Fórmula:C35H36F3N3O4Pureza:98.23% - 99.55%Cor e Forma:SolidPeso molecular:619.67Icariin
CAS:<p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>Fórmula:C33H40O15Pureza:97.82% - 98.3%Cor e Forma:SolidPeso molecular:676.66Glabrone
CAS:<p>Glabrone shows antiviral activity against influenza virus.</p>Fórmula:C20H16O5Pureza:99.08% - 99.55%Cor e Forma:SolidPeso molecular:336.34FH535
CAS:<p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>Fórmula:C13H10Cl2N2O4SPureza:98.25% - 99.5%Cor e Forma:SolidPeso molecular:361.2OPHIOPOGONIN D
CAS:<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Fórmula:C44H70O16Pureza:99.46% - ≥95%Cor e Forma:SolidPeso molecular:855.02SR1664
CAS:<p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>Fórmula:C33H29N3O5Pureza:98.02%Cor e Forma:SolidPeso molecular:547.6GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Fórmula:C13H9ClN2O3Pureza:98% - 99.95%Cor e Forma:Off-White SolidPeso molecular:276.68LJ570
CAS:<p>LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)</p>Fórmula:C27H22O3Pureza:99.64%Cor e Forma:SolidPeso molecular:394.46Angeloylgomisin H
CAS:<p>Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.</p>Fórmula:C28H36O8Pureza:99.84% - 99.95%Cor e Forma:SolidPeso molecular:500.58GW 501516
CAS:<p>GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.</p>Fórmula:C21H18F3NO3S2Pureza:98.91% - 99.64%Cor e Forma:White SolidPeso molecular:453.50NPC 15199
CAS:<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Fórmula:C21H23NO4Pureza:99.93% - 99.94%Cor e Forma:White Crystalline PowderPeso molecular:353.41Seladelpar
CAS:<p>Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.</p>Fórmula:C21H23F3O5SPureza:99.18% - 99.41%Cor e Forma:SolidPeso molecular:444.46Ciprofibrate
CAS:<p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>Fórmula:C13H14Cl2O3Pureza:99.63% - >99.99%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:289.15
