PPAR
Os receptores ativados por proliferadores de peroxissomas (PPARs) são um grupo de proteínas receptoras nucleares que funcionam como fatores de transcrição, regulando a expressão de genes envolvidos no metabolismo, particularmente no armazenamento de ácidos graxos e no metabolismo da glicose. Inibidores de PPAR são ferramentas importantes para o estudo de distúrbios metabólicos como diabetes, obesidade e doenças cardiovasculares. Esses inibidores podem modular o metabolismo lipídico, a sensibilidade à insulina e a inflamação, tornando-os valiosos na pesquisa terapêutica. Na CymitQuimica, oferecemos uma gama de inibidores de PPAR para apoiar sua pesquisa em doenças metabólicas, endocrinologia e desenvolvimento de medicamentos.
Foram encontrados 170 produtos de "PPAR"
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LJ570
CAS:LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)Fórmula:C27H22O3Pureza:99.64%Cor e Forma:SolidPeso molecular:394.46Ref: TM-T8374
1mg138,00€2mg202,00€5mg311,00€10mg445,00€25mg680,00€50mg888,00€100mg1.234,00€500mg2.475,00€1mL*10mM (DMSO)334,00€Ciprofibrate
CAS:Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Fórmula:C13H14Cl2O3Pureza:99.63% - >99.99%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:289.15L-165041
CAS:L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)Fórmula:C22H26O7Pureza:97.97%Cor e Forma:SolidPeso molecular:402.44GSK0660
CAS:GSK0660 is an antagonist and inverse agonist of PPARβ/δ.Fórmula:C19H18N2O5S2Pureza:99.26% - ≥95%Cor e Forma:SolidPeso molecular:418.49Ref: TM-T2674
2mg44,00€5mg65,00€10mg99,00€25mg175,00€50mg349,00€100mg520,00€500mg1.134,00€1mL*10mM (DMSO)65,00€OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Fórmula:C44H70O16Pureza:99.46% - ≥95%Cor e Forma:SolidPeso molecular:855.02XMD8-87
CAS:XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Fórmula:C24H27N7O2Pureza:98.05% - 99.89%Cor e Forma:SolidPeso molecular:445.52Ref: TM-T3709
2mg44,00€5mg70,00€10mg98,00€25mg178,00€50mg290,00€100mg480,00€500mg1.161,00€1mL*10mM (DMSO)84,00€GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Fórmula:C21H18F3NO3S2Pureza:98.91% - 99.64%Cor e Forma:White SolidPeso molecular:453.50XMD16-5
CAS:XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.Fórmula:C23H24N6O2Pureza:98.89% - 99.98%Cor e Forma:SolidPeso molecular:416.48Ref: TM-T3710
1mg44,00€2mg56,00€5mg90,00€10mg144,00€25mg225,00€50mg415,00€100mg615,00€500mg1.311,00€1mL*10mM (DMSO)90,00€Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.
Fórmula:C40H52O4Pureza:95.1% - 99.79%Cor e Forma:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Fórmula:C37H46O12Pureza:99.06% - ≥95%Cor e Forma:SolidPeso molecular:682.75(E/Z)-Elafibranor
CAS:GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.
Fórmula:C22H24O4SPureza:98.36%Cor e Forma:SolidPeso molecular:384.49Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Fórmula:C20H18O11Pureza:97.02% - 99.94%Cor e Forma:White PowderPeso molecular:434.35Ref: TM-T6S0117
1mg58,00€5mg97,00€10mg160,00€25mg283,00€50mg418,00€100mg615,00€200mg878,00€1mL*10mM (DMSO)111,00€Bilobetin
CAS:Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.Fórmula:C31H20O10Pureza:97% - 99.69%Cor e Forma:SolidPeso molecular:552.48Ref: TM-T4S2128
1mg44,00€2mg66,00€5mg137,00€10mg236,00€25mg403,00€50mg582,00€100mg800,00€1mL*10mM (DMSO)177,00€Choline Fenofibrate
CAS:Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic
Fórmula:C22H28ClNO5Pureza:98.82%Cor e Forma:SolidPeso molecular:421.91Pirinixic Acid
CAS:Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.Fórmula:C14H14ClN3O2SPureza:98.27% - 99.92%Cor e Forma:SolidPeso molecular:323.8Ref: TM-T2269
1g350,00€10mg48,00€25mg64,00€50mg79,00€100mg105,00€200mg148,00€500mg236,00€1mL*10mM (DMSO)47,00€Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Cor e Forma:SolidPeso molecular:274.36Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Cor e Forma:SolidPeso molecular:393.89GW1929
CAS:GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).
Fórmula:C30H29N3O4Pureza:98.1% - 98.21%Cor e Forma:SolidPeso molecular:495.57GSK3787
CAS:GSK3787 is a specific and irreversible PPARδ inhibitor（pIC50= 6.6）.Fórmula:C15H12ClF3N2O3SPureza:98% - 99.56%Cor e Forma:SolidPeso molecular:392.78Ref: TM-T1941
5mg55,00€10mg87,00€25mg173,00€50mg309,00€100mg520,00€500mg1.111,00€1mL*10mM (DMSO)55,00€Bocidelpar
CAS:Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.Fórmula:C25H27F3N2O3Pureza:97.77%Cor e Forma:SolidPeso molecular:460.49Ref: TM-T39516
1mg114,00€5mg260,00€10mg389,00€25mg703,00€50mg1.054,00€100mg1.468,00€1mL*10mM (DMSO)264,00€
