PPAR
Os receptores ativados por proliferadores de peroxissomas (PPARs) são um grupo de proteínas receptoras nucleares que funcionam como fatores de transcrição, regulando a expressão de genes envolvidos no metabolismo, particularmente no armazenamento de ácidos graxos e no metabolismo da glicose. Inibidores de PPAR são ferramentas importantes para o estudo de distúrbios metabólicos como diabetes, obesidade e doenças cardiovasculares. Esses inibidores podem modular o metabolismo lipídico, a sensibilidade à insulina e a inflamação, tornando-os valiosos na pesquisa terapêutica. Na CymitQuimica, oferecemos uma gama de inibidores de PPAR para apoiar sua pesquisa em doenças metabólicas, endocrinologia e desenvolvimento de medicamentos.
Foram encontrados 170 produtos de "PPAR"
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Licarin B
CAS:1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.Fórmula:C20H20O4Pureza:99.82% - ≥95%Cor e Forma:SolidPeso molecular:324.37Norathyriol
CAS:Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.Fórmula:C13H8O6Pureza:99.35% - 99.55%Cor e Forma:SolidPeso molecular:260.2Ref: TM-TN1990
1mg149,00€5mg354,00€10mg528,00€25mg852,00€50mg1.159,00€100mg1.568,00€200mg2.110,00€1mL*10mM (DMSO)472,00€Eupatilin
CAS:Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.Fórmula:C18H16O7Pureza:98.53% - 99%Cor e Forma:SolidPeso molecular:344.32Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Fórmula:C24H27NO5SPureza:98% - 99.8%Cor e Forma:Yellow SolidPeso molecular:441.54Ref: TM-T3170
2mg42,00€5mg62,00€10mg88,00€25mg172,00€50mg305,00€100mg558,00€500mg1.169,00€1mL*10mM (DMSO)85,00€DG172 dihydrochloride
CAS:DG172 dihydrochloride (DG-172 dihydrochloride) is an antagonist of PPARβ/δ(IC50 : 27 nM).
Fórmula:C20H22BrCl2N3Pureza:99.87%Cor e Forma:SolidPeso molecular:455.2Tetradecylthioacetic acid
CAS:Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.
Fórmula:C16H32O2SPureza:99.93%Cor e Forma:SolidPeso molecular:288.49T0070907
CAS:T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
Fórmula:C12H8ClN3O3Pureza:98.25% - 99.98%Cor e Forma:SolidPeso molecular:277.66Seladelpar
CAS:Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.Fórmula:C21H23F3O5SPureza:99.18% - 99.41%Cor e Forma:SolidPeso molecular:444.46Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:357.43GW9662
CAS:GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!Fórmula:C13H9ClN2O3Pureza:98% - 99.98%Cor e Forma:Off-White SolidPeso molecular:276.68SR1664
CAS:SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.Fórmula:C33H29N3O5Pureza:98.02%Cor e Forma:SolidPeso molecular:547.6Ref: TM-T23389
1mg52,00€2mg74,00€5mg111,00€10mg144,00€25mg284,00€50mg411,00€100mg590,00€200mg833,00€1mL*10mM (DMSO)123,00€FH535
CAS:FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.Fórmula:C13H10Cl2N2O4SPureza:98.25% - 99.5%Cor e Forma:SolidPeso molecular:361.2Ref: TM-T2413
5mg38,00€10mg57,00€25mg94,00€50mg164,00€100mg274,00€200mg404,00€500mg653,00€1mL*10mM (DMSO)64,00€Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Fórmula:C33H40O15Pureza:97.82% - 98.3%Cor e Forma:SolidPeso molecular:676.66GW6471
CAS:GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.Fórmula:C35H36F3N3O4Pureza:98.23% - 99.55%Cor e Forma:SolidPeso molecular:619.67Ref: TM-T8486
2mg35,00€5mg52,00€10mg88,00€25mg177,00€50mg311,00€100mg533,00€200mg802,00€1mL*10mM (DMSO)87,00€Palmitelaidic Acid
CAS:Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Fórmula:C16H30O2Pureza:99.76%Cor e Forma:SolidPeso molecular:254.41NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Fórmula:C19H13N3O7S2·2NaPureza:97.89%Cor e Forma:SolidPeso molecular:503.42Glabrone
CAS:Glabrone shows antiviral activity against influenza virus.Fórmula:C20H16O5Pureza:99.08% - 99.55%Cor e Forma:SolidPeso molecular:336.34Tesaglitazar
CAS:Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARαFórmula:C20H24O7SPureza:99.95%Cor e Forma:SolidPeso molecular:408.47Ref: TM-T17044
1mg46,00€5mg87,00€10mg137,00€25mg255,00€50mg427,00€100mg667,00€200mg924,00€1mL*10mM (DMSO)97,00€THR-0921
CAS:THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.Fórmula:C28H25NO7SPureza:100% - 99.83%Cor e Forma:SolidPeso molecular:519.5713-Oxo-9E,11E-octadecadienoic acid
CAS:13-Oxo-9E,11E-octadecadienoic acid from tomato juice, an isomer of 9-oxo-ODA, activates PPARα and lowers triglycerides in diabetic mice.Fórmula:C18H30O3Pureza:98%Cor e Forma:SolidPeso molecular:294.43
