Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.957 produtos)
- Antibiótico(920 produtos)
- Antifecção(23 produtos)
- DHFR(33 produtos)
- Síntese de DNA/RNA(708 produtos)
- HBV(176 produtos)
- HIV Protease(449 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5842 produtos de "Microbiologia/Virologia"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Anti-MRSA agent 27
CAS:<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Fórmula:C15H10F3N3OSCor e Forma:SolidPeso molecular:337.32EBOV-GP-IN-1
<p>EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).</p>Fórmula:C25H40ClN3O2Cor e Forma:SolidPeso molecular:450.06cis-RdRP-IN-5
<p>Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.</p>Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43Cap-dependent endonuclease-IN-5
CAS:<p>Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.</p>Fórmula:C27H21F2N3O4S2Cor e Forma:SolidPeso molecular:553.60Amicoumacin A
CAS:<p>Amicoumacin A has antibacterial activity. It also strongly suppresses inflammatory and ulcer activity.</p>Fórmula:C20H29N3O7Pureza:98%Cor e Forma:SolidPeso molecular:423.46Antimicrobial agent-38
CAS:<p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>Fórmula:C14H11N3O4SCor e Forma:SolidPeso molecular:317.32BMS-818251
CAS:<p>BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.</p>Fórmula:C29H26N6O5SCor e Forma:SolidPeso molecular:570.619MPro N3
CAS:<p>Mpro inhibitor blocks MHV-A29, HCoV-229E, FOPV (IC50: 2.7–8.8 μM), and SARS-CoV-2 (IC50: 16.8 μM) in plaque assays.</p>Fórmula:C35H48N6O8Cor e Forma:SolidPeso molecular:680.79CRS-3123
CAS:<p>CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.</p>Fórmula:C19H19Br2N3O2SPureza:98%Cor e Forma:SolidPeso molecular:513.258-Deazafolic acid
CAS:<p>8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.</p>Fórmula:C20H20N6O6Pureza:98%Cor e Forma:SolidPeso molecular:440.41GSK3739936
CAS:<p>GSK3739936 inhibits HIV-1 integrase (IC50: 11.1 nM, EC50: 1.7 nM), weak on CYP (IC50 >24.3 μM), rapid absorption, moderate clearance, high oral availability.</p>Fórmula:C34H43FN2O4Cor e Forma:SolidPeso molecular:562.71Bersiporocin
CAS:<p>Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.</p>Fórmula:C15H19Cl2N3OPureza:98.88% - 99.79%Cor e Forma:SolidPeso molecular:328.24LolCDE-IN-2
CAS:<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Fórmula:C22H17N5OPureza:98%Cor e Forma:SolidPeso molecular:367.40Antibacterial agent 76
<p>Antibacterial agent 76 (compound 9) is a potent antibacterial agent.</p>Fórmula:C23H27N3O2SCor e Forma:SolidPeso molecular:409.54Xanthosine-5'-Triphosphate trisodium
CAS:<p>Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).</p>Fórmula:C10H12N4Na3O15P3Cor e Forma:SolidPeso molecular:590.111ACHN-975
CAS:<p>ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.</p>Fórmula:C20H23N3O4Pureza:98%Cor e Forma:SolidPeso molecular:369.41MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Fórmula:C9H12BN7O5S2Peso molecular:373.18BI-2540
CAS:<p>BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .</p>Fórmula:C24H15ClF5NO5Cor e Forma:SolidPeso molecular:527.83Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Fórmula:C21H27N3SCor e Forma:SolidPeso molecular:353.52MIV-150
CAS:<p>MIV-150 is a nonnucleoside inhibitor of reverse transcriptase (NNRT). MIV-150 also blocking HIV-1 and HIV-2 infections (EC50<1 nM against HIV-1/HIV-2MN).</p>Fórmula:C19H17FN4O3Pureza:98%Cor e Forma:SolidPeso molecular:368.36LpxC-IN-10
CAS:<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Fórmula:C30H31N5O3Cor e Forma:SolidPeso molecular:509.6Saphenamycin
CAS:<p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>Fórmula:C23H18N2O5Pureza:98%Cor e Forma:SolidPeso molecular:402.40Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Fórmula:C19H21N5O2SCor e Forma:SolidPeso molecular:383.47MraY-IN-3
<p>MraY-IN-3 (12a) is a potent inhibitor of the bacterial translocase MraY (IC50: 140 μM). 46 μg/ml).</p>Fórmula:C35H45N3O5Cor e Forma:SolidPeso molecular:587.75BDM91288
CAS:<p>BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].</p>Fórmula:C17H22ClN5Cor e Forma:SolidPeso molecular:331.84Jun13296
CAS:<p>Jun13296 is an orally active quinoline SARS-CoV-2 papain-like protease inhibitor (IC50 = 0.13 µM, Ki = 8.8 nM). It demonstrates potent inhibitory effects against SARS-CoV-2 variants and Nirmatrelvir-resistant mutants. Jun13296 reduces lung viral titers and prevents lung tissue damage in SARS-CoV-2 infection models.</p>Fórmula:C30H34N6OCor e Forma:SolidPeso molecular:494.631KKL-40
CAS:<p>KKL-40 is a small-molecule inhibitor that targets the trans-translation process, effectively suppressing methicillin-sensitive and resistant Staphylococcus aureus (S. aureus) and other Gram-positive pathogens, including vancomycin-resistant Enterococcus faecium, Bacillus subtilis, and Streptococcus pyogenes. It works in synergy with the human antimicrobial peptide LL-37 to inhibit S. aureus, but does not show synergistic effects with other antibiotics such as daptomycin, kanamycin, or erythromycin. KKL-40 inhibits trans-translation, an extreme form of recoding, while being non-toxic to HeLa cells.</p>Fórmula:C16H9F4N3O2Cor e Forma:SolidPeso molecular:351.255VPC-80051
CAS:<p>VPC-80051 is an hnRNP A1 splicing activity inhibitor that directly interacts with the hnRNP A1 RBD and reduces AR-V7 messenger levels in the 22Rv1 CRPC cell line. VPC-80051 is applicable in prostate cancer research.</p>Fórmula:C16H13F2N3OCor e Forma:SolidPeso molecular:301.291Atramycin A
CAS:<p>Atramycin A is an anthraquinone antibiotic with antitumor properties.</p>Fórmula:C25H24O9Cor e Forma:SolidPeso molecular:468.453SARS-CoV-2-IN-24
<p>SARS-CoV-2-IN-24 blocks PLpro, altering its shape and stopping virus replication—useful for SARS-CoV-2 research.</p>Fórmula:C27H30N4O5Cor e Forma:SolidPeso molecular:490.55MA220607
CAS:<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Fórmula:C34H38INCor e Forma:SolidPeso molecular:587.58MTH1 activator-1
CAS:<p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>Fórmula:C29H23F3N4O2Cor e Forma:SolidPeso molecular:516.514PqsR-IN-1
<p>PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.</p>Fórmula:C17H18ClN3OSCor e Forma:SolidPeso molecular:347.86Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Fórmula:C18H16Br2O2Cor e Forma:SolidPeso molecular:424.13Rubropunctatin
CAS:<p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>Fórmula:C21H23NO4Cor e Forma:SolidPeso molecular:353.41MRL-494
<p>MRL-494, a small-molecule BamA inhibitor, resists efflux and outer membrane permeability, with antibacterial properties.</p>Fórmula:C26H35FN16O2Pureza:98%Cor e Forma:SolidPeso molecular:622.66Asukamycin
CAS:<p>Asukamycin, from S. nodosus asukaensis, is a polyketide antibiotic inhibiting tumor cells by activating caspases 8 and 3.</p>Fórmula:C31H34N2O7Cor e Forma:SolidPeso molecular:546.61Ceftolozane TFA
CAS:<p>Ceftolozane TFA is a cephalosporin class antibiotic (antibiotic) designed to inhibit Gram-negative bacterial infections. Additionally, it can be utilized in the synthesis of novel antibiotics (antibiotic) that are more efficacious and safer.</p>Fórmula:C25H31F3N12O10S2Cor e Forma:SolidPeso molecular:780.71DRF-8417
CAS:<p>DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.</p>Fórmula:C15H17N3O5SCor e Forma:SolidPeso molecular:351.38NSC 641396
CAS:<p>NSC 641396 is a ribonucleotide reductase (RNR) inhibitor with an IC50 value of 1.2 μM. Additionally, it acts as an inhibitor of protein arginine N-methyltransferase 9 (PRMT9) and exhibits antitumor properties.</p>Fórmula:C18H13NO3Cor e Forma:SolidPeso molecular:291.301SARS 3CLpro-IN-1
CAS:<p>SARS 3CLpro-IN-1: stereospecific SARS 3CL protease inhibitor, octahydroisochromene class, IC50 = 95 μM.</p>Fórmula:C22H38N4O2Cor e Forma:SolidPeso molecular:390.56trans-Clopenthixol
CAS:<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Fórmula:C22H25ClN2OSCor e Forma:SolidPeso molecular:400.965DNA crosslinker 6
CAS:<p>DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.</p>Fórmula:C19H21N7OCor e Forma:SolidPeso molecular:363.42Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Fórmula:C22H20Cl2N4SeCor e Forma:SolidPeso molecular:490.29Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Fórmula:C25H18N2O2SCor e Forma:SolidPeso molecular:410.49TCMDC-136230
<p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>Fórmula:C24H34N4O2SCor e Forma:SolidPeso molecular:442.62Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Fórmula:C16H11F2N3Cor e Forma:SolidPeso molecular:283.28Pol I-IN-1
<p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>Fórmula:C23H22N4O2Cor e Forma:SolidPeso molecular:386.45VNI
CAS:<p>VNI is an effective inhibitor of CYP51. It suppresses sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.</p>Fórmula:C26H19Cl2N5O2Cor e Forma:SolidPeso molecular:504.37Uridine 3',5'-diphosphate
CAS:<p>Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].</p>Fórmula:C9H14N2O12P2Cor e Forma:SolidPeso molecular:404.16SMCypI C31
<p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>Fórmula:C27H30N4O2SCor e Forma:SolidPeso molecular:474.62Anthelvencin A
CAS:<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Fórmula:C19H25N9O3Cor e Forma:SolidPeso molecular:427.46Carbonic anhydrase inhibitor 28
<p>Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.</p>Fórmula:C24H24FN5O7SCor e Forma:SolidPeso molecular:545.54TREX1-IN-4
CAS:<p>TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.</p>Fórmula:C24H19ClN6O4Cor e Forma:SolidPeso molecular:490.898HIV-1 inhibitor-8
<p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>Fórmula:C25H21N5OSCor e Forma:SolidPeso molecular:439.53SPB07935
CAS:<p>SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.</p>Fórmula:C22H15N5O4S2Cor e Forma:SolidPeso molecular:477.516CB 30900
CAS:<p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>Fórmula:C31H32FN5O9Cor e Forma:SolidPeso molecular:637.61HPH-15
CAS:<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>Fórmula:C19H31N3S4Cor e Forma:SolidPeso molecular:429.73PolQi1
CAS:<p>PolQi1 is a highly efficient and selective Polϴ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.</p>Fórmula:C18H14ClF5N4O2Pureza:98.97%Cor e Forma:SolidPeso molecular:448.77TREX1-IN-3
CAS:<p>TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.</p>Fórmula:C24H19ClN6O4Cor e Forma:SolidPeso molecular:490.898Chitin synthase inhibitor 11
<p>Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.</p>Fórmula:C24H24N4O8Cor e Forma:SolidPeso molecular:496.47Antibacterial agent 266
CAS:<p>Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.</p>Fórmula:C13H11N3OCor e Forma:SolidPeso molecular:225.246Pneumolysin-IN-1
CAS:<p>Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].</p>Fórmula:C23H16Cl2N2O4Cor e Forma:SolidPeso molecular:455.29NDM-1 inhibitor-7
CAS:<p>NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.</p>Fórmula:C9H10N2OS2Cor e Forma:SolidPeso molecular:226.319TAN-1057C
CAS:<p>TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).</p>Fórmula:C13H25N9O3Cor e Forma:SolidPeso molecular:355.4KWR095
CAS:<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Fórmula:C33H31ClF3N9O4Cor e Forma:SolidPeso molecular:710.105Fosmanogepix
CAS:<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Fórmula:C22H21N4O6PPureza:98%Cor e Forma:SolidPeso molecular:468.40Arterolane
CAS:<p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>Fórmula:C22H36N2O4Cor e Forma:SolidPeso molecular:392.53Antibacterial synergist 1
<p>Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.</p>Fórmula:C19H24N2O4Cor e Forma:SolidPeso molecular:344.4HSV-TK substrate
CAS:<p>HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.</p>Fórmula:C11H15N5O4Pureza:98%Cor e Forma:SolidPeso molecular:281.27PRRSV-IN-1
CAS:<p>PRRSV-IN-1 (Compound 4s) acts as an inhibitor of the nsp4 protease of PRRSV. It has an EC50 value of 0.45 μM against PRRSV, binds to the nsp4 protease with a Kd of 29.24 pM, and exhibits an IC50 value of 80.36 pM for nsp4 protease inhibition. PRRSV-IN-1 is applicable in antiviral infection research.</p>Fórmula:C19H18BrNO3Cor e Forma:SolidPeso molecular:388.255SARS-CoV-2-IN-8
<p>SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).</p>Fórmula:C35H38N6O3Cor e Forma:SolidPeso molecular:590.71MK-3402
CAS:<p>MK-3402 is a metallo-beta-lactamase inhibitor. MK-3402can be used in the research of bacteria .</p>Fórmula:C15H19N9O5S2Cor e Forma:SolidPeso molecular:469.50N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
<p>N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].</p>Fórmula:C11H9FN4OCor e Forma:SolidPeso molecular:232.21PfCLK3-IN-1
<p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>Fórmula:C28H27ClN4O4Cor e Forma:SolidPeso molecular:518.99MTI013
<p>MTI013 is a selective inhibitor of SARS-CoV-2 nsp14 Mtase (IC50: 2.98 µM) and an antiviral agent (IC50: 10.33 µM in HCoV-229E infected Huh7 cells). Additionally, MTI013 demonstrates synergistic antiviral effects when used in conjunction with the RdRp inhibitor SHEN26.</p>Fórmula:C24H26N6O4SCor e Forma:SolidPeso molecular:494.57Antibacterial agent 204
CAS:<p>Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].</p>Fórmula:C14H18N2Cor e Forma:SolidPeso molecular:214.31HIV-1 inhibitor-52
CAS:<p>HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.</p>Fórmula:C46H72FNO5SCor e Forma:SolidPeso molecular:770.13HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Fórmula:C21H32ClN7O3Cor e Forma:SolidPeso molecular:465.98Flutimide
CAS:<p>Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.</p>Fórmula:C12H18N2O3Cor e Forma:SolidPeso molecular:238.28HBV-IN-18
<p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>Fórmula:C17H15F6N5O2Cor e Forma:SolidPeso molecular:435.322'-(2-Nitrobenzyl)-ATP
CAS:<p>2'-(2-Nitrobenzyl)-ATP is an analog of rATP. It acts as a transcription terminator by inhibiting the elongation of RNA chains by T7 RNA polymerase.</p>Fórmula:C17H21N6O15P3Cor e Forma:SolidPeso molecular:642.30CDA-IN-4
CAS:<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Fórmula:C10H9BrN4O2SCor e Forma:SolidPeso molecular:329.17(R)-CSN5i-3
CAS:<p>(R)-CSN5i-3 is CSN5i-3 of the R configuration.</p>Fórmula:C28H29F2N5O2Pureza:99.76% - 99.97%Cor e Forma:SolidPeso molecular:505.56OUN58101
CAS:<p>OUN58101, also MDK-8101/BI-D, is an RSV L-protein inhibitor with no formal name, first reported in patent WO 2005042530.</p>Fórmula:C32H36N6O6Cor e Forma:SolidPeso molecular:600.66Ladirubicin
CAS:<p>Ladirubicin, as an anthracyclines analog is the leading compound of alkylcyclines.</p>Fórmula:C29H31NO11SCor e Forma:SolidPeso molecular:601.62Antibacterial agent 90
<p>Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.</p>Fórmula:C30H42N2O6Cor e Forma:SolidPeso molecular:526.66Dioxidine
CAS:<p>Dioxidine is an antimicrobial agent that can inhibit bacterial growth. It is utilized in research on pyogenic infections.</p>Fórmula:C10H10N2O4Cor e Forma:SolidPeso molecular:222.197Plm IV inhibitor-2
CAS:<p>"Plm IV inhibitor-2: Potent for Plm IV (IC50=24nM), affects Plm II/Plm I; malaria research compound."</p>Fórmula:C39H54N4O4Cor e Forma:SolidPeso molecular:642.87D-G23
CAS:<p>D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.</p>Fórmula:C19H22N4O3Cor e Forma:SolidPeso molecular:354.403XR8-69
<p>XR8-69 is a SARS-CoV-2 PLpro inhibitor. XR8-69 has a low micromolar antiviral effect in SARS-CoV-2 infected human cells.</p>Fórmula:C26H30N4O2SCor e Forma:SolidPeso molecular:462.61HCV-IN-7
CAS:<p>HCV-IN-7: potent oral HCV NS5A inhibitor, pan-genotypic, IC50s 3-47 pM, good pharmacokinetics, favorable liver uptake.</p>Fórmula:C40H48N8O6SPureza:98%Cor e Forma:SolidPeso molecular:768.92PptT-IN-1
<p>PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.</p>Fórmula:C18H29N5O2Cor e Forma:SolidPeso molecular:347.46Mycobacterium Tuberculosis-IN-6
CAS:<p>Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 μM. It is useful in antibacterial research.</p>Fórmula:C19H20FNOCor e Forma:SolidPeso molecular:297.367PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Fórmula:C24H24N2O2Cor e Forma:SolidPeso molecular:372.46DIDS
CAS:<p>DIDS inhibits anion exchangers reversibly then irreversibly and blocks RAD51.</p>Fórmula:C16H10N2O6S4Pureza:98%Cor e Forma:SolidPeso molecular:454.52Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Fórmula:C19H18F4O2Cor e Forma:SolidPeso molecular:354.34Xeruborbactam
CAS:<p>QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.</p>Fórmula:C10H8BFO4Pureza:98%Cor e Forma:SolidPeso molecular:221.98AN-12-H5
CAS:<p>AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.</p>Fórmula:C24H23N3O4S3Cor e Forma:SolidPeso molecular:513.65JPL
CAS:JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Fórmula:C19H20Cl2O2Cor e Forma:SolidPeso molecular:351.27
