Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.957 produtos)
- Antibiótico(920 produtos)
- Antifecção(23 produtos)
- DHFR(33 produtos)
- Síntese de DNA/RNA(708 produtos)
- HBV(176 produtos)
- HIV Protease(449 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5842 produtos de "Microbiologia/Virologia"
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Antimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Fórmula:C15H16BrN3O2Cor e Forma:SolidPeso molecular:350.21BM635 mesylate
<p>BM635 mesylate inhibits MmpL3; kills Divergent bacterium with 0.6 µM MIC50; boosts bioavailability.</p>Fórmula:C26H33FN2O4SCor e Forma:SolidPeso molecular:488.61Enantiomer of Sofosbuvir
<p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45Cap-dependent endonuclease-IN-6
CAS:<p>Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.</p>Fórmula:C23H21N3O3SCor e Forma:SolidPeso molecular:419.5Faldaprevir
CAS:<p>Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.</p>Fórmula:C40H49BrN6O9SPureza:99.04% - 99.19%Cor e Forma:SolidPeso molecular:869.82Aurantiogliocladin
CAS:<p>Aurantiogliocladin is a mild antibiotic effective against Staphylococcus epidermidis, but it shows no efficacy against Staphylococcus aureus. It is also capable of inhibiting biofilm formation.</p>Fórmula:C10H12O4Cor e Forma:SolidPeso molecular:196.2EBOV-IN-10
CAS:<p>EBOV-IN-10 is an orally active inhibitor of the Ebola virus (EBOV) with an EC50 value of 0.19 μM.</p>Fórmula:C22H22N2O2SCor e Forma:SolidPeso molecular:378.49HIV-1 inhibitor-18
<p>HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).</p>Fórmula:C27H31N3O6SCor e Forma:SolidPeso molecular:525.62LN-439A
CAS:<p>LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.</p>Fórmula:C24H26FN3O4Cor e Forma:SolidPeso molecular:439.482-Acetyl-2-decarboxamidotetracycline
CAS:<p>2-Acetyl-2-decarboxamidotetracycline is a tetracycline-class antibiotic. It exhibits a UV absorption spectrum similar to that of tetracycline or 5-oxytetracycline at concentrations above 300 mμ, characteristic of the BCD ring system.</p>Fórmula:C23H25NO8Cor e Forma:SolidPeso molecular:443.45QPX7728 bis-acetoxy methyl ester
CAS:<p>QPX7728 bis-acetoxy methyl ester is an inhibitor of boronic acid β-lactamase.</p>Fórmula:C15H14BFO8Pureza:98%Cor e Forma:SolidPeso molecular:352.085-Fluorouridine 5'-phosphate
CAS:<p>5-Fluorouridine 5'-phosphate acts as an ODCase (uridine 5'-monophosphate decarboxylase) inhibitor, exhibiting a Ki value of 98 µM for human ODCase and 645 µM for Methanococcus jannaschii ODCase. This compound also shows inhibitory activity on leukemia and lymphoma cell lines, making it useful for cancer research studies.</p>Fórmula:C9H12FN2O9PCor e Forma:SolidPeso molecular:342.172(E)-Antiviral agent 67
CAS:<p>(E)-Antiviral agent 67 (compound PC6) is a pyrazolone-based antiviral compound that exhibits inhibitory activity against RNA-dependent RNA polymerase.</p>Fórmula:C19H19N3OCor e Forma:SolidPeso molecular:305.374Gln-AMS TFA
<p>Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.</p>Fórmula:C17H23F3N8O10SCor e Forma:SolidPeso molecular:588.47Polθ-IN-7
CAS:<p>Polθ-IN-7 (example 12) is an inhibitor of DNA polymerase θ (Polθ) with a Ki of 1.27 nM.</p>Fórmula:C28H35F3N6O2Cor e Forma:SolidPeso molecular:544.612Etofamide
CAS:<p>Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.</p>Fórmula:C19H20Cl2N2O5Cor e Forma:SolidPeso molecular:427.28Antibiotic U 44590
CAS:<p>5,6-Dihydro-5-azathymidine exhibits activity against both Gram-positive and Gram-negative bacteria, as well as DNA viruses.</p>Fórmula:C9H15N3O5Cor e Forma:SolidPeso molecular:245.23Triazophos
CAS:<p>Triazophos is a non-systemic pesticide that acts as an acetylcholinesterase (AChE) inhibitor, forming a covalent and irreversible bond with the acetylcholine binding site. This action blocks the hydrolysis of acetylcholine, leading to increased excitability. It is effective against a wide range of soil insects and mites, including aphids, thrips, midges, beetles, lepidopteran larvae, mole crickets, and red spiders. Triazophos is suitable for use on various crops such as ornamental plants, cotton, rice, corn, soybeans, oil palm, olives, and coffee.</p>Fórmula:C12H16N3O3PSCor e Forma:SolidPeso molecular:313.31Pyriftalid
CAS:<p>Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.</p>Fórmula:C15H14N2O4SCor e Forma:SolidPeso molecular:318.35PqsR-IN-1
<p>PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.</p>Fórmula:C17H18ClN3OSCor e Forma:SolidPeso molecular:347.86PF 03709270
CAS:<p>PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.</p>Fórmula:C19H27NO7S3Pureza:98%Cor e Forma:SolidPeso molecular:477.61FtsZ-IN-4
<p>FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 >20μg/mL).</p>Fórmula:C21H16ClF2NO2Cor e Forma:SolidPeso molecular:387.81KPC-2-IN-2
<p>KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.</p>Fórmula:C12H10BN3O2SCor e Forma:SolidPeso molecular:271.1ONO-5334
CAS:<p>ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).</p>Fórmula:C21H34N4O4SPureza:98.22% - 99.60%Cor e Forma:SolidPeso molecular:438.58Arterolane maleate
CAS:<p>Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.</p>Fórmula:C26H40N2O8Pureza:98%Cor e Forma:SolidPeso molecular:508.612Chitin synthase inhibitor 7
<p>Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.</p>Fórmula:C24H25N3O5Cor e Forma:SolidPeso molecular:435.477-Hydroxytropolone
CAS:<p>7-Hydroxytropolone (3-Hydroxytropolone) is an antibiotic that exhibits activity against Gram-positive and Gram-negative bacteria, as well as yeasts and fungi. It also functions as an inhibitor of 2''-O-adenylate transferase.</p>Fórmula:C7H6O3Cor e Forma:SolidPeso molecular:138.12MCB-3681
CAS:<p>MCB-3681, active against gram-positive bacterium, is the antibacterial Oxaquin's active substance.</p>Fórmula:C31H32F2N4O8Cor e Forma:SolidPeso molecular:626.6NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Fórmula:C20H25ClN4O3SPureza:98%Cor e Forma:SolidPeso molecular:436.96Cap-dependent endonuclease-IN-25
CAS:<p>Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)</p>Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48DXR-IN-3
CAS:<p>DXR-IN-3 is an anti-Toxoplasma DXR inhibitor. It exhibits in vitro activity against the TgDXR enzyme, with an IC50 value of 0.62 μM and a Ki value of 0.19 μM. Furthermore, DXR-IN-3 can inhibit the proliferation of Toxoplasma, displaying an IC50 value of 5.46 μM.</p>Fórmula:C10H12Cl2NO5PSCor e Forma:SolidPeso molecular:360.15Secutrelvir
CAS:<p>Secutrelvir inhibits the 3CL protease (3CL protease), thereby exhibiting antiviral activity by preventing the replication of SARS-CoV-2.</p>Fórmula:C23H16Cl2F3N5O2Cor e Forma:SolidPeso molecular:522.307Urease-IN-1
<p>Urease -IN-1 is a urease inhibitor (IC50: 2.21±0.45 μM).</p>Fórmula:C17H12BrFN4O2SCor e Forma:SolidPeso molecular:435.27Streptothricin F
CAS:<p>Streptothricin F is a biochemical.</p>Fórmula:C19H34N8O8Cor e Forma:SolidPeso molecular:502.52E6-272
CAS:<p>E6-272, an inhibitor of HPV 16, induced early and late apoptosis in HPV16-positive cervical cancer cells and inhibited the proliferation of SiHa and CaSki.</p>Fórmula:C26H28N2OPureza:99.82%Cor e Forma:SolidPeso molecular:384.51Saptomycin E
CAS:<p>Saptomycin E is an antitumor antibiotic.</p>Fórmula:C33H35NO9Cor e Forma:SolidPeso molecular:589.63Purine phosphoribosyltransferase-IN-2
<p>Purine PRTase-IN-2 inhibits Pf, Pv, Tbr PRT; Ki: 30, 20, 2 nM.</p>Fórmula:C11H15N5Na4O10P2Cor e Forma:SolidPeso molecular:531.17Cap-dependent endonuclease-IN-2
<p>Cap-dependent endonuclease-IN-2 strongly blocks influenza A virus RNA polymerase; it's a CEN inhibitor.</p>Fórmula:C30H24FN3O7SCor e Forma:SolidPeso molecular:589.59SARS-CoV-2 3CLpro-IN-28
CAS:<p>SARS-CoV-2 3CLpro-IN-28 (Compound 19) is an inhibitor of SARS-CoV-2 3CLpro, exhibiting an IC50 value of 0.018 μM.</p>Fórmula:C27H18Cl2N4O4Cor e Forma:SolidPeso molecular:533.362Carumonam Sodium
CAS:<p>Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials.</p>Fórmula:C12H12N6Na2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:510.37Bilanafos
CAS:<p>Bilanafos is an agent of Anti-Bacterial.</p>Fórmula:C11H22N3O6PPureza:98%Cor e Forma:SolidPeso molecular:323.28Anti-MRSA agent 2
CAS:<p>Anti-MRSA agent 2 inhibits MRSA at 0.098 μg/ml, with low toxicity and disrupts bacterial membranes and DNA.</p>Fórmula:C18H10Br2N2OCor e Forma:SolidPeso molecular:430.09RAD51-IN-5
CAS:<p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>Fórmula:C26H38N4O5S2Cor e Forma:SolidPeso molecular:550.73UMPK ligand 1
CAS:<p>UMPK ligand 1 (ZINC07785412) serves as a ligand for uridine monophosphate kinase (UMPK).</p>Fórmula:C15H22N4O5SCor e Forma:SolidPeso molecular:370.424Kikumycin A
CAS:<p>Kikumycin A, an antibiotic produced by Streptomyces, exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria. Additionally, it demonstrates antitrichomonal activity with a minimum inhibitory concentration (MIC) of 25 μg/mL against Trichomonas foetus.</p>Fórmula:C13H17N7O2Cor e Forma:SolidPeso molecular:303.32FWM-1
<p>FWM-1 blocks SARS-CoV-2 NSP13, hinders ATP binding, with -328.6 kcal/mol binding energy.</p>Fórmula:C15H11ClN4O4S2Cor e Forma:SolidPeso molecular:410.86HBV-IN-24
<p>HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.</p>Fórmula:C23H27NO6Cor e Forma:SolidPeso molecular:413.46(S)-Batylalcohol
CAS:<p>(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.</p>Fórmula:C21H44O3Cor e Forma:SolidPeso molecular:344.572GTSE1-IN-1
CAS:<p>GTSE1-IN-1 (compound Y18), an orally active GTSE1 inhibitor, exhibits notable anticancer properties. It effectively represses the proliferation of cancer cells by downregulating GTSE1 transcription and expression, which leads to DNA damage and promotes persistent cell cycle arrest and cellular senescence. Moreover, GTSE1-IN-1 substantially reduces the adhesion, migration, and invasion of colorectal cancer HCT116 cells and non-small cell lung cancer A549 cells in vitro.</p>Fórmula:C21H24FN7Cor e Forma:SolidPeso molecular:393.46DNA ligase-IN-2
CAS:<p>DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is >64 μg/mL.</p>Fórmula:C13H8FN3O3Cor e Forma:SolidPeso molecular:273.219
