Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.957 produtos)
- Antibiótico(920 produtos)
- Antifecção(23 produtos)
- DHFR(33 produtos)
- Síntese de DNA/RNA(708 produtos)
- HBV(176 produtos)
- HIV Protease(449 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5842 produtos de "Microbiologia/Virologia"
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VV261
CAS:<p>VV261 is an orally active inhibitor of the Influenza Virus. It exhibits activity against the Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and the Lymphocytic Choriomeningitis Virus (LCMV), with EC50 values of 0.89 and 0.15, respectively.</p>Fórmula:C28H34FN3O11Cor e Forma:SolidPeso molecular:607.58Anti-MRSA agent 27
CAS:<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Fórmula:C15H10F3N3OSCor e Forma:SolidPeso molecular:337.32NS2B/NS3-IN-3
CAS:<p>NS2B/NS3-IN-3 (Compd 66) is an inhibitor of Flavivirus NS2B-NS3 protease [1] .</p>Fórmula:C19H21N3O2Cor e Forma:SolidPeso molecular:323.39Tuberculosis inhibitor 5
<p>Compound 11i: potent, non-toxic anti-tuberculosis biphenyl analogue.</p>Fórmula:C25H18N2O2SCor e Forma:SolidPeso molecular:410.49UNC0638 hydrate
CAS:<p>UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.</p>Fórmula:C30H49N5O3Cor e Forma:SolidPeso molecular:527.74WR-27653
CAS:<p>WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.</p>Fórmula:C20H36BrN3O2Cor e Forma:SolidPeso molecular:430.423SARS-CoV-2-IN-102
CAS:<p>SARS-CoV-2-IN-102 (example 58) is an inhibitor of the SARS-CoV papain-like protease (SARS-CoVPLpro), demonstrating an IC50 of less than 100 nM.</p>Fórmula:C29H34F2N6O2Cor e Forma:SolidPeso molecular:536.62Artefenomel
CAS:<p>Artefenomel (OZ439) is an orally active anti-malarial ozone analog with antiviral activity for the study of SARS-CoV-2 infections and malaria infections.</p>Fórmula:C28H39NO5Cor e Forma:SolidPeso molecular:469.61Antitubercular agent-23
<p>Antitubercular agent-23 combats Candida albicans (MIC: 1.1 μg/ml) and M. tuberculosis (MIC: 1 μg/ml).</p>Fórmula:C20H22FN5O8SCor e Forma:SolidPeso molecular:511.48Antibiofilm agent-4
CAS:<p>Antibiofilm agent-4 is a LasR inhibitor, demonstrating optimal antibiofilm and anti-QS (quorum sensing) properties.</p>Fórmula:C15H15NO3Peso molecular:257.28MK-8876
CAS:<p>MK-8876 is an Inhibitor of HCV NS5B Site D.</p>Fórmula:C32H24F2N4O5SPureza:98%Cor e Forma:SolidPeso molecular:614.62GSK 932121
CAS:<p>GSK 932121: potent antimalarial, targets P. falciparum by inhibiting cytochrome bc1 in the electron transport chain.</p>Fórmula:C20H15ClF3NO4Pureza:98%Cor e Forma:SolidPeso molecular:425.79Antimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Fórmula:C15H16BrN3O2Cor e Forma:SolidPeso molecular:350.21Antifungal agent 113
CAS:<p>Antifungalagent 113 (compound 9a) serves as an effective antifungal and antibacterial agent. It exhibits strong inhibitory activity against both S. aureus and methicillin-resistant S. aureus.</p>Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.40HRSV/HMPV-IN-1
CAS:<p>HRSV/HMPV-IN-1 (compound 3) is an inhibitor targeting HRSV/HMPV, exhibiting EC50 values of < 0.2 μM against human RSV-A and < 0.5 μM for human MPV A2 TN/94-49. This compound is utilized in the study of bronchiolitis and pneumonia.</p>Fórmula:C34H31ClF2N4O5SCor e Forma:SolidPeso molecular:681.15NBD-10007
CAS:NBD-10007 is an inhibitor of HIV-1 entry.Fórmula:C20H25ClN4O3SPureza:98%Cor e Forma:SolidPeso molecular:436.96Antibacterial agent 63
CAS:<p>Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a</p>Fórmula:C35H43N9O14S2Cor e Forma:SolidPeso molecular:877.9Anthelvencin A
CAS:<p>Anthelvencin A is a pyrrolylamide metabolite with moderate antibacterial and anthelmintic activity.</p>Fórmula:C19H25N9O3Cor e Forma:SolidPeso molecular:427.46MED6-189
CAS:<p>MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.</p>Fórmula:C17H26N2OCor e Forma:SolidPeso molecular:274.40TREX1-IN-4
CAS:<p>TREX1-IN-4 (Compound 96) is an inhibitor of TREX1 and TREX2, exhibiting an IC50 of less than 0.1 μM for TREX1 and an IC50 of less than 1 μM for TREX2. It has an EC50 ranging from 0.1 to 10 μM in HCT116 cells. TREX1-IN-4 is applicable for research in the field of cancer.</p>Fórmula:C24H19ClN6O4Cor e Forma:SolidPeso molecular:490.898SPB07935
CAS:<p>SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.</p>Fórmula:C22H15N5O4S2Cor e Forma:SolidPeso molecular:477.516HPH-15
CAS:<p>HPH-15 is an anti-cell migration compound that inhibits cell movement by binding to hnRNP U or suppressing TGF-β. Additionally, it prevents epithelial-to-mesenchymal transition (EMT). HPH-15 holds potential for research in areas such as anti-tumor metastasis and anti-fibrosis.</p>Fórmula:C19H31N3S4Cor e Forma:SolidPeso molecular:429.73TREX1-IN-3
CAS:<p>TREX1-IN-3 (Compound 95) is an inhibitor of TREX1 and TREX2, with an IC50 of less than 0.1 μM for TREX1 and less than 1 μM for TREX2, as well as an EC50 of less than 1 μM for HCT116 cells. It is applicable for research in the field of cancer.</p>Fórmula:C24H19ClN6O4Cor e Forma:SolidPeso molecular:490.898Arohynapene B
CAS:<p>Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.</p>Fórmula:C18H22O3Cor e Forma:SolidPeso molecular:286.366Antifungal agent 39
CAS:<p>Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.</p>Fórmula:C23H22ClN3O5Cor e Forma:SolidPeso molecular:455.89L 702007
CAS:<p>L 702007 is an inhibitor of HIV-1 reverse transcriptase.</p>Fórmula:C18H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:315.41Antibacterial agent 266
CAS:<p>Antibacterialagent 266 (Compound C5) is an inhibitor of plant pathogenic bacteria that disrupts the integrity of bacterial cell membranes. It exhibits an EC50 of 24.1 μg/mL against Xanthomonasoryzaepvoryzae (Xoo) and 39.0 μg/mL against X. axonopodispvcitri (Xac). Antibacterialagent 266 is valuable for research in plant pathology and the development of agricultural antibacterial agents.</p>Fórmula:C13H11N3OCor e Forma:SolidPeso molecular:225.246Aurachin C
CAS:<p>Aurachin C is a quinoline alkaloid belonging to the isoprenoid class, known for its antimalarial, antifungal, and antibacterial properties. It acts as a selective terminal oxidase inhibitor.</p>Fórmula:C25H33NO2Cor e Forma:SolidPeso molecular:379.535GT-055
<p>GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.</p>Fórmula:C13H20F3N5O8SCor e Forma:SolidPeso molecular:463.39Polθ-IN-5
CAS:<p>Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.</p>Fórmula:C23H18ClF2N7O3SCor e Forma:SolidPeso molecular:545.95NDM-1 inhibitor-7
CAS:<p>NDM-1 inhibitor-7 (Compound A8) is an NDM-1 inhibitor with an IC50 of 10.284 μM. It restores the ability of meropenem (MEM) to penetrate the cell wall of Gram-negative bacteria and effectively reinstates MEM's antibacterial activity against NDM-1 positive Escherichia coli. Moreover, NDM-1 inhibitor-7 demonstrates significant efficacy in both Galleria mellonella and murine peritonitis infection models.</p>Fórmula:C9H10N2OS2Cor e Forma:SolidPeso molecular:226.319KWR095
CAS:<p>KWR095 is an orally active inhibitor of WRN, demonstrating an IC50 of 0.032 μM against WRN ATPase. It disrupts the double-stranded helicase activity of WRN and inhibits tumor cell proliferation, exhibiting antitumor properties.</p>Fórmula:C33H31ClF3N9O4Cor e Forma:SolidPeso molecular:710.105Eravacycline
CAS:<p>Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent.</p>Fórmula:C27H31FN4O8Pureza:97.46%Cor e Forma:SolidPeso molecular:558.56Ipronidazole
CAS:<p>Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.</p>Fórmula:C7H11N3O2Cor e Forma:SolidPeso molecular:169.18SLU-10906
CAS:<p>SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.</p>Fórmula:C22H21BFN5O2Cor e Forma:SolidPeso molecular:417.244NEU-1017
CAS:<p>NEU-1017 serves as a broad-spectrum antiparasitic compound, effectively inhibiting T. brucei, L. major, and P. falciparum with EC50 values of 210 nM, 240 nM, and 3 nM, respectively.</p>Fórmula:C33H31ClFN5O3SCor e Forma:SolidPeso molecular:632.147Arterolane
CAS:<p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>Fórmula:C22H36N2O4Cor e Forma:SolidPeso molecular:392.53Cap-dependent endonuclease-IN-7
CAS:<p>Cap-dependent endonuclease-IN-7, a potent CEN inhibitor, blocks viral mRNA synthesis and virus spread, with research use for influenza A, B, C.</p>Fórmula:C36H28FN3O7SCor e Forma:SolidPeso molecular:665.69(4-Aminobenzoyl)-D-glutamic acid
CAS:<p>(4-Aminobenzoyl)-D-glutamic acid (Compound 17) exhibits competitive inhibitory activity against the H2-pterin synthesis system, affecting folic acid synthesis and subsequently inhibiting bacterial growth.</p>Fórmula:C12H14N2O5Cor e Forma:SolidPeso molecular:266.25Antibacterial agent 62
<p>Novel anti-TB agent 62 is a redox compound with bactericidal activity against active and dormant bacteria.</p>Fórmula:C24H33BrN2O2Cor e Forma:SolidPeso molecular:461.44HBV-IN-20
<p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>Cor e Forma:SolidHSV-TK substrate
CAS:<p>HSV-TK substrate is a substrate for HSV-TK with antitumor activity. It induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells.</p>Fórmula:C11H15N5O4Pureza:98%Cor e Forma:SolidPeso molecular:281.27ABT-072
CAS:<p>ABT-072 is a nonnucleoside NS5B polymerase inhibitor and a candidate drug evaluated for treatment of hepatitis C virus.</p>Fórmula:C24H27N3O5SPureza:98%Cor e Forma:SolidPeso molecular:469.55NNRT-IN-5
CAS:<p>NNRT-IN-5 (compound 10d) is an orally available non-nucleoside reverse transcriptase (Reverse Transcriptase) inhibitor.</p>Fórmula:C27H22N8Cor e Forma:SolidPeso molecular:458.52Rubropunctatin
CAS:<p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>Fórmula:C21H23NO4Cor e Forma:SolidPeso molecular:353.41Antitubercular agent-11
<p>Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].</p>Fórmula:C16H15N3O4Cor e Forma:SolidPeso molecular:313.31QPX7728 methoxy acetoxy methy ester
CAS:<p>QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.</p>Fórmula:C14H14BFO7Pureza:98%Cor e Forma:SolidPeso molecular:324.07Pyriftalid
CAS:<p>Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.</p>Fórmula:C15H14N2O4SCor e Forma:SolidPeso molecular:318.35Ganaplacide hydrochloride
CAS:<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Fórmula:C22H24ClF2N5OPureza:93.97%Cor e Forma:SoildPeso molecular:447.91Squalamine lactate
CAS:<p>Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.</p>Fórmula:C37H71N3O8SPureza:98%Cor e Forma:SolidPeso molecular:718.04
