Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 693 produtos de "Células - tronco e Derivados"

Pureza (%)

100

produtos por página.

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KY19382
CAS:
- 2226664-93-1
KY19382, a dual CXXC5-DVL and GSK3β inhibitor (IC50s: 19/10 nM), boosts Wnt/β-catenin signaling and may help in metabolic disease research.
Fórmula:C₁₇H₁₁Cl₂N₃O₂
Pureza:98.06%
Cor e Forma:Solid
Peso molecular:360.19
Ref: TM-T9025
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MYF-01-37
CAS:
- 2416417-65-5
MYF-01-37 (1-[3-Methyl-3-[3-(trifluoromethyl)anilino]pyrrolidin-1-yl]prop-2-en-1-one) is a novel covalent TEAD inhibitor.
Fórmula:C₁₅H₁₇F₃N₂O
Pureza:99.46% - 99.5%
Cor e Forma:Solid
Peso molecular:298.3
Ref: TM-T22372
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AT9283
CAS:
- 896466-04-9
AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).
Fórmula:C₁₉H₂₃N₇O₂
Pureza:99.83% - 99.98%
Cor e Forma:Solid
Peso molecular:381.43
Ref: TM-T3068
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Curculigoside
CAS:
- 85643-19-2
1.
Fórmula:C₂₂H₂₆O₁₁
Pureza:99.85%
Cor e Forma:Solid
Peso molecular:466.44
Ref: TM-T6S1966
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CEP-33779
CAS:
- 1257704-57-6
CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.
Fórmula:C₂₄H₂₆N₆O₂S
Pureza:98.24% - ≥95%
Cor e Forma:Solid
Peso molecular:462.57
Ref: TM-T6122
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Baricitinib phosphate
CAS:
- 1187595-84-1
Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.
Fórmula:C₁₆H₂₀N₇O₆PS
Pureza:99.4% - 99.82%
Cor e Forma:Solid
Peso molecular:469.41
Ref: TM-T2360
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WHI-P97 HCl
WHI-P97 HCl is a potent and selective JAK-3 inhibitor.
Fórmula:C₁₆H₁₄Br₂ClN₃O₃
Pureza:99.49%
Cor e Forma:Solid
Peso molecular:491.56
Ref: TM-T4657L
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SJ000291942
CAS:
- 425613-09-8
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.
Fórmula:C₁₆H₁₅FN₂O₄
Pureza:99.66%
Cor e Forma:Solid
Peso molecular:318.3
Ref: TM-T4662
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ZINC00881524
CAS:
- 557782-81-7
ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.
Fórmula:C₂₁H₂₀N₂O₃S
Pureza:99.48%
Cor e Forma:Solid
Peso molecular:380.46
Ref: TM-T4095
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IWP-2
CAS:
- 686770-61-6
IWP-2 is a Wnt pathway inhibitor and an ATP-competitive CK1δ inhibitor. IWP-2 inhibits self-renewal of embryonic stem cells. Cost effective and quality assured.
Fórmula:C₂₂H₁₈N₄O₂S₃
Pureza:96.1% - 99.49%
Cor e Forma:Solid
Peso molecular:466.6
Ref: TM-T2702
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Indirubin-3′-oxime
CAS:
- 667463-82-3
Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.
Fórmula:C₁₆H₁₁N₃O₂
Pureza:98.34%
Cor e Forma:Solid
Peso molecular:277.28
Ref: TM-T9138
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3,5-Bis(4-nitrophenoxy)benzoic acid
CAS:
- 173550-33-9
3,5-Bis(4-nitrophenoxy)benzoic acid (Compound W) is an inhibitor of γ-secretase. It decreases the released levels of Aβ42 and notch-1 Aβ-like peptide 25.
Fórmula:C₁₉H₁₂N₂O₈
Pureza:99.14%
Cor e Forma:Solid
Peso molecular:396.31
Ref: TM-T22678
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Abrocitinib
CAS:
- 1622902-68-4
Abrocitinib (PF-04965842) (PF-04965842) is a potent, specific and orally-active JAK1 inhibitor (IC50s: 29/803 nM for JAK1/2).
Fórmula:C₁₄H₂₁N₅O₂S
Pureza:99.09% - 99.91%
Cor e Forma:Solid
Peso molecular:323.41
Ref: TM-TQ0037
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LF3
CAS:
- 664969-54-4
LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 < 2 μM)
Fórmula:C₂₀H₂₄N₄O₂S₂
Pureza:99.63%
Cor e Forma:Solid
Peso molecular:416.56
Ref: TM-T7399
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LSKL, Inhibitor of Thrombospondin TSP-1 2TFA
LSKL, Inhibitor of Thrombospondin TSP-1 acetate is activation of TGF-β .
Fórmula:C₂₅H₄₄F₆N₆O₉
Pureza:99.75%
Cor e Forma:Solid
Peso molecular:686.64
Ref: TM-T7676
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Fasudil hydrochloride
CAS:
- 105628-07-7
Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.
Fórmula:C₁₄H₁₈ClN₃O₂S
Pureza:99.54% - ≥95%
Cor e Forma:White Solid
Peso molecular:327.83
Ref: TM-T3060
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SC99
CAS:
- 882290-02-0
SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.
Fórmula:C₁₅H₈Cl₂FN₃O
Pureza:99.56%
Cor e Forma:Solid
Peso molecular:336.15
Ref: TM-T8719
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Kartogenin
CAS:
- 4727-31-5
Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
Fórmula:C₂₀H₁₅NO₃
Pureza:96.25% - 97.79%
Cor e Forma:Solid
Peso molecular:317.34
Ref: TM-T1748
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TBB
CAS:
- 17374-26-4
TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).
Fórmula:C₆HBr₄N₃
Pureza:98.51% - 99.45%
Cor e Forma:Off-White Solid
Peso molecular:434.71
Ref: TM-T2695
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ITD-1
CAS:
- 1099644-42-4
ITD-1 is a potent and highly selective TGFβ pathway inhibitor.
Fórmula:C₂₇H₂₉NO₃
Pureza:99.89% - >99.99%
Cor e Forma:Solid
Peso molecular:415.52
Ref: TM-T2273