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Células - tronco e Derivados

Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 693 produtos de "Células - tronco e Derivados"

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  • JAK-IN-18
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    JAK-IN-18

    CAS:
    <p>"JAK-IN-18: potent JAK inhibitor for eye, skin, respiratory disease research (WO2018204238A1, comp 1)."</p>
    Fórmula:C27H28F2N6O3
    Cor e Forma:Solid
    Peso molecular:522.55

    Ref: TM-T63658

  • JAK-IN-28
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    JAK-IN-28

    CAS:
    <p>JAK-IN-28 (Compound 111) is a Janus kinase (JAK) inhibitor potentially applicable in the research of cancer and inflammatory diseases [1].</p>
    Fórmula:C20H18ClN7O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:407.86

    Ref: TM-T79116

  • JAK-IN-30
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    JAK-IN-30

    CAS:
    <p>JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50</p>
    Fórmula:C19H26N8S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:398.53

    Ref: TM-T79235

  • PIMPC
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    PIMPC

    CAS:
    <p>PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibits</p>
    Fórmula:C21H19N5O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:357.41

    Ref: TM-T79693

  • Aβ42-IN-2
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    Aβ42-IN-2

    CAS:
    <p>Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].</p>
    Fórmula:C24H26N6O2
    Pureza:98.09% - 99.87%
    Cor e Forma:Solid
    Peso molecular:430.5

    Ref: TM-T9641

  • γ-secretase modulator 2
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    γ-secretase modulator 2

    CAS:
    <p>Gamma-secretase modulator 2 selectively targets Alzheimer's by reducing Aβ(1-42), aiding in prevention and treatment.</p>
    Fórmula:C25H22F4N6O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:514.47

    Ref: TM-T11359

  • tCFA15
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    tCFA15

    CAS:
    <p>tCFA15: A trimethylated long-chain fatty alcohol with a 15-carbon side chain; may regulate Notch signaling and neuron differentiation.</p>
    Fórmula:C24H44O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:364.61

    Ref: TM-T13917

  • Chromenone 1
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    Chromenone 1

    CAS:
    <p>Chromenone 1 is a potent potentiator of osteogenic bone morphogenetic protein (BMP).</p>
    Fórmula:C18H10F3N3O2
    Pureza:99.83% - 99.93%
    Cor e Forma:Solid
    Peso molecular:357.29

    Ref: TM-T61301

  • γ-Secretase modulator 4
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    γ-Secretase modulator 4

    CAS:
    <p>γ-Secretase modulator 4 is a potent γ-secretase modulator, reduces the Aβ42 level with IC50s of 0.017 μM and 0.014 μM in mouse and human, respectively.</p>
    Fórmula:C23H19FN4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:402.42

    Ref: TM-T11361

  • TK4g
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    TK4g

    CAS:
    <p>TK4g, a potent JAK inhibitor, has IC50s of 12.61 nM (JAK2) &amp; 15.80 nM (JAK3); promising for lymphoid diseases &amp; leukemia research.</p>
    Fórmula:C19H19N3O4S
    Cor e Forma:Solid
    Peso molecular:385.44

    Ref: TM-T61698

  • JAK1-IN-4
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    JAK1-IN-4

    CAS:
    <p>JAK1-IN-4 selectively blocks JAK1 (IC50 = 85 nM) over JAK2/JAK3 and halts STAT3 phosphorylation in NCI-H 1975 cells (IC50 = 227 nM).</p>
    Fórmula:C26H32FN9O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:521.59

    Ref: TM-T15606

  • TyK2-IN-2
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    TyK2-IN-2

    CAS:
    <p>TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).</p>
    Fórmula:C16H18N6O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:310.35

    Ref: TM-T13232

  • GSK3-IN-2
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    GSK3-IN-2

    CAS:
    <p>GSK3-IN-2 is a potent GSK3 inhibitor for the treatment of diabetes and neurodegenerative diseases.</p>
    Fórmula:C17H19N3OS
    Pureza:98.8%
    Cor e Forma:Solid
    Peso molecular:313.42

    Ref: TM-T73270

  • JAK3/BTK-IN-2
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    JAK3/BTK-IN-2

    CAS:
    <p>JAK3/ BTk-in-2 is a potent JAK3/BTK inhibitor.</p>
    Fórmula:C25H32N8O2
    Pureza:99.64% - 99.87%
    Cor e Forma:Solid
    Peso molecular:476.57

    Ref: TM-T9813

  • Aloisine B
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    Aloisine B

    CAS:
    <p>Aloisine B (AloisineB) inhibited cyclin-dependent kinase and glycogen synthase kinase with IC50 values of 0.85 µM and 0.75 µM, respectively.</p>
    Fórmula:C15H14ClN3
    Pureza:95.15%
    Cor e Forma:Solid
    Peso molecular:271.74

    Ref: TM-T69188

  • VT103
    Targetmol
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    VT103

    CAS:
    <p>VT103, an oral TEAD1 palmitoylation inhibitor, shows promise against various cancers by disrupting YAP/TAZ-TEAD interactions.</p>
    Fórmula:C18H17F3N4O2S
    Pureza:99.58%
    Cor e Forma:Solid
    Peso molecular:410.41

    Ref: TM-T62077

  • Lorpucitinib
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    Lorpucitinib

    CAS:
    <p>Lorpucitinib (JNJ-64251330) is a JAK kinase inhibitor used in the study of inflammatory and gastrointestinal diseases.</p>
    Fórmula:C22H28N6O2
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:408.5

    Ref: TM-T62053

  • (2R,5S)-Ritlecitinib
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    (2R,5S)-Ritlecitinib

    CAS:
    <p>(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective inhibitor of JAK3 with IC 50 of 144.8 nM[1].</p>
    Fórmula:C15H19N5O
    Cor e Forma:Solid
    Peso molecular:285.34

    Ref: TM-T60565

  • Povorcitinib
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    Povorcitinib

    CAS:
    <p>Povorcitinib is a highly potent and selective JAK1 inhibitor with significant potential for the investigation of cutaneous lupus erythematosus (CLE) and Lichen planus (LP).</p>
    Fórmula:C23H22F5N7O
    Cor e Forma:Solid
    Peso molecular:507.469

    Ref: TM-T39113

  • TYK2-IN-11
    Targetmol
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    TYK2-IN-11

    CAS:
    <p>TYK2-IN-11 (5B) selectively inhibits TYK2 (IC50: 0.016 nM) and JAK1 (IC50: 0.31 nM), aiding autoimmune and inflammatory disease research.</p>
    Fórmula:C18H17N5O3S
    Cor e Forma:Solid
    Peso molecular:383.42

    Ref: TM-T61658