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Células - tronco e Derivados

Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 693 produtos de "Células - tronco e Derivados"

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  • CJJ300
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    CJJ300

    CAS:
    <p>CJJ300 is a TGF-β inhibitor disrupting TGF-β-TβR complex formation, with an IC50 of 5.3 μM, and halts cell migration.</p>
    Fórmula:C30H33N3
    Pureza:99.80%
    Cor e Forma:Solid
    Peso molecular:435.6

    Ref: TM-T62483

  • EP009
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    EP009

    CAS:
    <p>EP009, a novel, selective, and orally active inhibitor of JAK3, induces therapeutic response in T-cell malignancies.</p>
    Fórmula:C14H24O2
    Cor e Forma:Solid
    Peso molecular:224.34

    Ref: TM-T27274

  • OICR-0547
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    OICR-0547

    CAS:
    <p>OICR-0547 is an inactive derivative of OICR-9429 and is commonly used as a negative control for OICR-9429.</p>
    Fórmula:C28H29F3N4O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:542.55

    Ref: TM-T12290

  • CK2α-IN-1
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    CK2α-IN-1

    CAS:
    <p>CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and can</p>
    Fórmula:C16H11N3O4S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:341.34

    Ref: TM-T73269

  • CK2-IN-4
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    CK2-IN-4

    CAS:
    <p>CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 µM.</p>
    Fórmula:C18H11N3O4S
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:365.36

    Ref: TM-T73375

  • JAK3/BTK-IN-1
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    JAK3/BTK-IN-1

    CAS:
    <p>JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two important</p>
    Fórmula:C25H28N8O
    Pureza:97.89%
    Cor e Forma:Solid
    Peso molecular:456.54

    Ref: TM-T9814

  • inS3-54-A26
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    inS3-54-A26

    CAS:
    <p>inS3-54-A26 is an inhibitor of the DNA-binding domain of STAT3. inS3-54-A26 suppresses tumor growth, metastasis and the gene expression of STAT3.</p>
    Fórmula:C25H19ClN2O2
    Pureza:99.57%
    Cor e Forma:Solid
    Peso molecular:414.88

    Ref: TM-T27613

  • JAK-IN-14
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    JAK-IN-14

    CAS:
    <p>JAK-IN-14 (compound 16) is a specific JAK1 inhibitor. It prevents JAK1 phosphorylation by binding to the active site of JAK in immune, inflammation and cancer.</p>
    Fórmula:C19H15FN4O
    Pureza:98.27%
    Cor e Forma:Solid
    Peso molecular:334.35

    Ref: TM-T9764

  • Tyk2-IN-5
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    Tyk2-IN-5

    CAS:
    <p>Tyk2-IN-5 is a selective and orally active inhibitor of Tyk2 JH2 (Ki: 0.086 nM for Tyk2 JH2; IC50: 25 nM for IFNα).</p>
    Fórmula:C21H19FN8O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:434.43

    Ref: TM-T13234

  • H-1152
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    H-1152

    CAS:
    <p>H-1152 is a potent, specific, ATP-competitive, and cell permeable ROCK inhibitor (Ki = 1.6 nM).</p>
    Fórmula:C16H21N3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:319.42

    Ref: TM-T7552

  • TEAD-IN-2
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    TEAD-IN-2

    CAS:
    <p>TEAD-IN-2 is a potent and bifunctional TEAD inhibitor to induce TEAD protein degradation via the ubiquitination pathway, with anticancer potential.</p>
    Fórmula:C16H18BrF3N2O
    Cor e Forma:Solid
    Peso molecular:391.23

    Ref: TM-T61776

  • CAY10746
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    CAY10746

    CAS:
    <p>CAY10746 selectively inhibits ROCK I/II with IC50s: 0.014/0.003 μM, useful for diabetic retinopathy research.</p>
    Fórmula:C26H23N3O5
    Pureza:99.04%
    Cor e Forma:Solid
    Peso molecular:457.48

    Ref: TM-T36196

  • ELN318463
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    ELN318463

    CAS:
    <p>ELN 318463 selectively inhibits γ-secretase; EC50: 12 nM (PS1), 656 nM (PS2); 51x more selective for PS1; targets APP.</p>
    Fórmula:C19H20BrClN2O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:471.8

    Ref: TM-T11178

  • JAK3-IN-12
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    JAK3-IN-12

    CAS:
    <p>JAK3-IN-12 (compound 15k) is a potent inhibitor of JAK3 (IC50: 9.5 nM) and can be used in the study of rheumatoid arthritis.</p>
    Fórmula:C19H19N5O4S
    Cor e Forma:Solid
    Peso molecular:413.45

    Ref: TM-T62114

  • GSK-3β inhibitor 12
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    GSK-3β inhibitor 12

    CAS:
    <p>GSK-3β inhibitor 12 is a selective GSK-3β inhibitor.GSK-3β inhibitor 12 inhibits 49.11% of 25 μM GSK-3β activity and 37.11% of 50 μM GSK-3β activity.GSK-3β</p>
    Fórmula:C14H13N3OS
    Pureza:98.58%
    Cor e Forma:Solid
    Peso molecular:271.34

    Ref: TM-T60472

  • SR-1277
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    SR-1277

    CAS:
    <p>SR-1277 is a potent, highly selective and ATP-competitive CK1δ/ε inhibitor, regulating Wee1 activity at the G2/M cell-cycle interface, and antiproliferative.</p>
    Fórmula:C21H19N9O3S
    Cor e Forma:Solid
    Peso molecular:477.5

    Ref: TM-T38927

  • JAK-IN-11
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    JAK-IN-11

    CAS:
    <p>JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.</p>
    Fórmula:C23H22FN5O4S
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:483.52

    Ref: TM-T12549

  • LY-411575 isomer 1
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    LY-411575 isomer 1

    CAS:
    <p>LY-411575 isomer 1 is a potent γ-secretase inhibitor. LY-411575 isomer 1 is an isomer of LY411575.</p>
    Fórmula:C26H23F2N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:479.48

    Ref: TM-T11903

  • Logotipo do CymitQuimica
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    AF-2112

    <p>AF-2112, a TEAD inhibitor derived from Flufenamic acid, significantly diminishes the expression of CTGF, Cyr61, Axl, and NF2.</p>
    Fórmula:C21H18FNO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:351.37

    Ref: TM-T79428

  • TEAD-IN-6
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    TEAD-IN-6

    CAS:
    <p>TEAD-IN-6 (Example 11-1) is a TEAD modulator that inhibits the YAP1/TAZ-TEAD interaction, and has applications in cancer research [1].</p>
    Fórmula:C19H17F3N4O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:438.42

    Ref: TM-T79687