Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1527 produtos para "Autofagia".
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Carboplatin
CAS:Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.Fórmula:C6H12N2O4PtPureza:98% - 99.72%Cor e Forma:White SolidPeso molecular:371.25Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Fórmula:C33H40N2O9Pureza:98.85% - 99.99%Cor e Forma:White SolidPeso molecular:608.68Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Cor e Forma:Pale-Yellow SolidPeso molecular:488.01Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Fórmula:C21H27ClN2S2Pureza:99.55% - 99.95%Cor e Forma:White SolidPeso molecular:407.04Matrine
CAS:Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.Fórmula:C15H24N2OPureza:99.77% - >99.99%Cor e Forma:White SolidPeso molecular:248.36Paclitaxel
CAS:Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.Fórmula:C47H51NO14Pureza:98% - 99.92%Cor e Forma:White SolidPeso molecular:853.91Raloxifene hydrochloride
CAS:Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Fórmula:C28H28ClNO4SPureza:98% - 99.97%Cor e Forma:SolidPeso molecular:510.044Naringin
CAS:Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.Fórmula:C27H32O14Pureza:99.23%Cor e Forma:White SolidPeso molecular:580.53Sodium salicylate
CAS:Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.Fórmula:C7H5NaO3Pureza:99.36% - 99.92%Cor e Forma:SolidPeso molecular:160.11Rhein
CAS:Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.Fórmula:C15H8O6Pureza:99.04% - 99.72%Cor e Forma:Yellow SolidPeso molecular:284.22Irinotecan hydrochloride trihydrate
CAS:Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Fórmula:C33H45ClN4O9Pureza:98.22% - 99.96%Cor e Forma:Yellow SolidPeso molecular:677.18Pemetrexed
CAS:Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).Fórmula:C20H21N5O6Pureza:98.1% - 99.92%Cor e Forma:SolidPeso molecular:427.41BIX 02565
CAS:BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).Fórmula:C26H30N6O2Pureza:97.44% - 99.7%Cor e Forma:SolidPeso molecular:458.56Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Fórmula:C22H29FO5Pureza:98% - 99.91%Cor e Forma:Crystals From Ether (Ntp 1992)Peso molecular:392.46Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Fórmula:C10H16ClN5Pureza:97.11% - 99.80%Cor e Forma:White SolidPeso molecular:241.72Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Fórmula:C23H34O5Pureza:99.12%Cor e Forma:SolidPeso molecular:390.51Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Fórmula:C9H13N3O5Pureza:99.83% - 99.93%Cor e Forma:White SolidPeso molecular:243.22Avermectin B1
CAS:Avermectin B1 is served as anthelmintic and insecticide.Fórmula:C48H72O14Pureza:mixture - mixtureCor e Forma:SolidPeso molecular:873.09Crustecdysone
CAS:Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.Fórmula:C27H44O7Pureza:99.06% - 99.67%Cor e Forma:White SolidPeso molecular:480.63Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Fórmula:C22H23N3O4Pureza:98.19% - 99.98%Cor e Forma:White SolidPeso molecular:393.44Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:SolidPeso molecular:433.45Sophocarpine monohydrate
CAS:Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Fórmula:C15H22N2OPureza:99.55%Cor e Forma:White SolidPeso molecular:246.35Thalidomide
CAS:Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.Fórmula:C13H10N2O4Pureza:98.88% - 99.88%Cor e Forma:SolidPeso molecular:258.23AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Fórmula:C27H30FN5O3Pureza:98.82%Cor e Forma:White SolidPeso molecular:491.56Ref: TM-T14381
1mg70,00€5mg152,00€1mL*10mM (DMSO)166,00€10mg236,00€25mg432,00€50mg647,00€100mg964,00€Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Cor e Forma:White SolidPeso molecular:925.46Sunitinib Malate
CAS:Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Fórmula:C26H33FN4O7Pureza:98% - 99.26%Cor e Forma:SolidPeso molecular:532.56TTNPB
CAS:TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),Fórmula:C24H28O2Pureza:99.55%Cor e Forma:White SolidPeso molecular:348.48Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!Fórmula:C66H76Cl3N9O24Pureza:97.20% - 99.91%Cor e Forma:White SolidPeso molecular:1485.71Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFórmula:C25H35N7O9S4Pureza:99.63%Cor e Forma:SolidPeso molecular:705.85Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Fórmula:C14H24Cl2N2O3Pureza:99.58%Cor e Forma:White SolidPeso molecular:339.258Doxazosin mesylate
CAS:Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.Fórmula:C24H29N5O8SPureza:99.92%Cor e Forma:White SolidPeso molecular:547.58Tepotinib
CAS:Tepotinib (EMD-1214063) is a selective, orally, and ATP-competitive c-MET tyrosine kinase inhibitor. Tepotinib has antitumor effect. Cost-effective and quality-assured.Fórmula:C29H28N6O2Pureza:98% - 99.91%Cor e Forma:SolidPeso molecular:492.57Succinylsulfathiazole
CAS:Succinylsulfathiazole (Succinylsulphathiazole) is a sulfonamide. An ultra long-acting drug.Fórmula:C13H13N3O5S2Pureza:98.77%Cor e Forma:SolidPeso molecular:355.39Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Fórmula:C27H29NO11·HClPureza:98% - 99.99%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Fórmula:C8H12BrNO3Pureza:98.59% - 99.88%Cor e Forma:Brown SolidPeso molecular:250.09Motixafortide TFA(664334-36-5,Free)
Motixafortide TFA is a CXCR4 antagonist with ~1 nM IC50, promoting AML apoptosis by modulating miR-15a/16-1 and downregulating ERK and BCL-2.Fórmula:C99H145F4N33O21S2Pureza:>99.99%Cor e Forma:White SolidPeso molecular:2273.54Amiodarone hydrochloride
CAS:Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.Fórmula:C25H29I2NO3·HClPureza:99.81% - 99.98%Cor e Forma:White SolidPeso molecular:681.78Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFórmula:C21H18O11Pureza:90.08% - 99.32%Cor e Forma:SolidPeso molecular:446.36Ref: TM-T2775
50mg34,00€100mg49,00€200mg49,00€1mL*10mM (DMSO)50,00€500mg55,00€1g80,00€2g102,00€5g152,00€Ketanserin
CAS:Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Fórmula:C22H22FN3O3Pureza:99.19% - 99.73%Cor e Forma:SolidPeso molecular:395.43Pyrazinamide
CAS:Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amideFórmula:C5H5N3OPureza:99.71% - 99.95%Cor e Forma:White SolidPeso molecular:123.11Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Fórmula:CH4N2O2Pureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:76.05Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Cor e Forma:White SolidPeso molecular:494Lomustine
CAS:Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Fórmula:C9H16ClN3O2Pureza:98.36% - 99.44%Cor e Forma:Solid SolidPeso molecular:233.7Colistin sulfate
CAS:Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Fórmula:C53H100N16O17SPureza:98% - 99.80%Cor e Forma:White SolidPeso molecular:1253.51MLi-2
CAS:MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.Fórmula:C21H25N5O2Pureza:98.96%Cor e Forma:SolidPeso molecular:379.46Ref: TM-T16115
1mg55,00€2mg84,00€5mg126,00€1mL*10mM (DMSO)135,00€10mg178,00€25mg409,00€50mg618,00€100mg880,00€Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Fórmula:C24H32O4SPureza:99.87%Cor e Forma:White PowderPeso molecular:416.57Nicardipine hydrochloride
CAS:Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.Fórmula:C26H30ClN3O6Pureza:99.58% - 99.89%Cor e Forma:White SolidPeso molecular:515.99NBDHEX
CAS:NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Fórmula:C12H15N3O4SPureza:97.38%Cor e Forma:Yellow SolidPeso molecular:297.33Chenodeoxycholic acid
CAS:Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!Fórmula:C24H40O4Pureza:99.70% - 99.93%Cor e Forma:White SolidPeso molecular:392.57Xylitol
CAS:Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group.Fórmula:C5H12O5Pureza:99.89% - 99.95%Cor e Forma:White SolidPeso molecular:152.15
