Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1506 produtos de "Autofagia"
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Fluvastatin sodium
CAS:Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterolFórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:Light Yellow Solid PowderPeso molecular:433.45Glucosamine hydrochloride
CAS:Glucosamine hydrochloride (Chitosamine hydrochloride) is commonly used as a treatment for osteoarthritis, although its acceptance as a medical therapy varies.Fórmula:C6H13NO5·HClPureza:99.77%Cor e Forma:White Solid CrystallinePeso molecular:215.63BIX 02565
CAS:BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).Fórmula:C26H30N6O2Pureza:97.44% - 99.7%Cor e Forma:SolidPeso molecular:458.56Ref: TM-T5428
25mgA consultar50mgA consultar1mg52,00€2mg74,00€5mg112,00€1mL*10mM (DMSO)138,00€10mg167,00€Reserpine
CAS:Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.Fórmula:C33H40N2O9Pureza:98.85% - 99.99%Cor e Forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecular:608.68Dihydroartemisinin
CAS:Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!Fórmula:C15H24O5Pureza:98% - 99.41%Cor e Forma:White SolidPeso molecular:284.35Erlotinib hydrochloride
CAS:Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Fórmula:C22H23N3O4·HClPureza:99.78% - 99.85%Cor e Forma:White Or Off-White PowderPeso molecular:429.90Lapatinib ditosylate monohydrate
CAS:Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.
Fórmula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPureza:98% - 99.41%Cor e Forma:Colourless To Light-Yellow CrystalPeso molecular:943.47FAAH-IN-2
CAS:FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) is a potent inhibitor of FAAH(fatty acid amide hydrolase).Fórmula:C15H11ClFN3O2Pureza:99.18%Cor e Forma:Tan SolidPeso molecular:319.72Naproxen sodium
CAS:Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.Fórmula:C14H13NaO3Pureza:99.68% - 99.93%Cor e Forma:White PowderPeso molecular:252.249-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Fórmula:C22H13FN2O5Pureza:99.32%Cor e Forma:SolidPeso molecular:404.35Ref: TM-T14066
1mg50,00€2mg66,00€5mg94,00€1mL*10mM (DMSO)110,00€10mg155,00€25mg309,00€50mg447,00€100mg667,00€Raloxifene hydrochloride
CAS:Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.Fórmula:C28H28ClNO4SPureza:98% - 99.97%Cor e Forma:Light Yellow SolidPeso molecular:510.044Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Fórmula:C23H19F3N4O3Pureza:97.53%Cor e Forma:SolidPeso molecular:456.42Quetmolimab
CAS:Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis.Pureza:SDS-PAGE:95% SEC-HPLC:97.59%Cor e Forma:LiquidPeso molecular:150 kDaSinomenine hydrochloride
CAS:Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.Fórmula:C19H24ClNO4Pureza:99.43%Cor e Forma:SolidPeso molecular:365.85Daunorubicin hydrochloride
CAS:Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFórmula:C27H29NO10·HClPureza:96.21% - 99.53%Cor e Forma:Cancer DrugPeso molecular:563.99Ref: TM-T1511
5mg34,00€10mg52,00€1mL*10mM (DMSO)59,00€25mg87,00€50mg113,00€100mg177,00€200mg281,00€500mg442,00€Erlotinib
CAS:Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Fórmula:C22H23N3O4Pureza:98.19% - 99.98%Cor e Forma:White To Off-White PowderPeso molecular:393.44Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFórmula:C21H18O11Pureza:90.08% - 99.32%Cor e Forma:Yellow PowderPeso molecular:446.36Ref: TM-T2775
50mg34,00€100mg49,00€200mg49,00€1mL*10mM (DMSO)50,00€500mg55,00€1g80,00€2g102,00€5g152,00€Tranexamic acid
CAS:Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.Fórmula:C8H15NO2Pureza:99.64% - 99.79%Cor e Forma:White Crystalline PowderPeso molecular:157.21Acesulfame Potassium
CAS:Acesulfame potassium is a non-nutritive sweetener.Fórmula:C4H4KNO4SPureza:99.65%Cor e Forma:White Solid CrystallinePeso molecular:201.24Sophocarpine monohydrate
CAS:Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Fórmula:C15H22N2OPureza:99.55%Cor e Forma:SolidPeso molecular:246.35Dehydrocholic acid
CAS:Dehydrocholic acid (Dehystolin) is a synthetic bile acid, produced by the oxidation of cholic acid.Fórmula:C24H34O5Pureza:98.58%Cor e Forma:White To Off-White Amorphous PowderPeso molecular:402.52Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Fórmula:C18H14N4O5SPureza:98.00% - 99.28%Cor e Forma:Minute Brownish-Yellow CrystalsPeso molecular:398.39Vitamin B3-d4
CAS:Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is a deuterated substitute for Niacin and can be used to track Niacin metabolism in vivo.
Fórmula:C6HD4NO2Pureza:99.86%Cor e Forma:SolidPeso molecular:127.13Sulfacetamide sodium monohydrate
CAS:Sulfacetamide sodium monohydrate is a sulfonamide antibiotic. It has been investigated for the treatment of rosacea and pityriasis versicolor.Fórmula:C8H9N2NaO3S·H2OPureza:99.92%Cor e Forma:White Crystalline PowderPeso molecular:254.2Ponatinib Hydrochloride
CAS:Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib.Fórmula:C29H28ClF3N6OPureza:99.88%Cor e Forma:SolidPeso molecular:569.02Clioquinol
CAS:Clioquinol: oral, lipophilic copper-binder; halogenated quinoline with antifungal, antiparasitic, and possible antitumor uses.Fórmula:C9H5ClINOPureza:97.02%Cor e Forma:Brownish-Yellow Bulky Powder Decomposes At 178-179°C Used As A Topical Anti-InfectivePeso molecular:305.5Dexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Fórmula:C22H29FO5Pureza:98% - 99.91%Cor e Forma:Crystals From Ether (Ntp 1992)Peso molecular:392.46Dexamethasone acetate
CAS:Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Fórmula:C24H31FO6Pureza:99.22% - 99.65%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:434.50Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Fórmula:C10H16ClN5Pureza:97.11% - 99.80%Cor e Forma:Lactic AcidosisPeso molecular:241.72Pyrazinamide
CAS:Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amideFórmula:C5H5N3OPureza:99.71% - 99.95%Cor e Forma:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Peso molecular:123.11Mevastatin
CAS:Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.Fórmula:C23H34O5Pureza:99.12%Cor e Forma:White-Yellowish To Yellow Powder Solid PowderPeso molecular:390.51Avermectin B1
CAS:Avermectin B1 is served as anthelmintic and insecticide.Fórmula:C48H72O14Pureza:mixture - mixtureCor e Forma:White PowderPeso molecular:873.09Cytarabine
CAS:Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).Fórmula:C9H13N3O5Pureza:99.83% - 99.93%Cor e Forma:Fine Off-White Crystalline PowderPeso molecular:243.22Lomustine
CAS:Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Fórmula:C9H16ClN3O2Pureza:98.36% - 99.44%Cor e Forma:Solid SolidPeso molecular:233.7Nicardipine hydrochloride
CAS:Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.Fórmula:C26H30ClN3O6Pureza:99.58% - 99.89%Cor e Forma:Yellow SolidPeso molecular:515.99Crustecdysone
CAS:Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.
Fórmula:C27H44O7Pureza:99.06% - 99.67%Cor e Forma:Canary Yellow Fine PowderPeso molecular:480.63NBDHEX
CAS:NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).Fórmula:C12H15N3O4SPureza:97.38%Cor e Forma:SolidPeso molecular:297.33AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Fórmula:C27H30FN5O3Pureza:98.82%Cor e Forma:SolidPeso molecular:491.56Ref: TM-T14381
1mg70,00€5mg152,00€1mL*10mM (DMSO)166,00€10mg236,00€25mg432,00€50mg647,00€100mg964,00€Carboplatin
CAS:Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.
Fórmula:C6H12N2O4PtPureza:98% - 99.72%Cor e Forma:White Crystalline PowderPeso molecular:371.25Irinotecan Hydrochloride
CAS:Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Fórmula:C33H39ClN4O6Pureza:98% - 99.94%Cor e Forma:Yellow Crystalline PowderPeso molecular:623.14Ref: TM-T0486L
10mg34,00€25mg49,00€50mg65,00€1mL*10mM (DMSO)71,00€100mg89,00€200mg129,00€500mg254,00€Paclitaxel
CAS:Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.
Fórmula:C47H51NO14Pureza:98% - 99.92%Cor e Forma:White PowderPeso molecular:853.91Oxaliplatin
CAS:Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.Fórmula:C8H14N2O4PtPureza:97% - 99.93%Cor e Forma:SolidPeso molecular:397.29Sunitinib Malate
CAS:Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Fórmula:C26H33FN4O7Pureza:98% - 99.26%Cor e Forma:SolidPeso molecular:532.56Thalidomide
CAS:Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.Fórmula:C13H10N2O4Pureza:98.88% - 99.88%Cor e Forma:White SolidPeso molecular:258.23Rhein
CAS:Rhein (NSC 38629) is an anthraquinone compound extracted from Polygonaceae Rheum Officinale with anti-inflammation and antitumor activities.Fórmula:C15H8O6Pureza:99.04% - 99.72%Cor e Forma:Physical Description Yellow Needles (From Methanol) Or Yellow-Brown Powder (Ntp 1992)Peso molecular:284.22Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!Fórmula:C66H76Cl3N9O24Pureza:97.20% - 99.19%Cor e Forma:Off White PowderPeso molecular:1485.71Memantine hydrochloride
CAS:Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.Fórmula:C12H22ClNPureza:99.56% - 99.96%Cor e Forma:Crystalline SolidPeso molecular:215.76TTNPB
CAS:TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),Fórmula:C24H28O2Pureza:99.55%Cor e Forma:White SolidPeso molecular:348.48Irinotecan hydrochloride trihydrate
CAS:Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.Fórmula:C33H45ClN4O9Pureza:98.22% - >99.99%Cor e Forma:Pale Yellow To Yellow Crystalline PowderPeso molecular:677.18Simvastatin
CAS:Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Fórmula:C25H38O5Pureza:98.54% - 99.13%Cor e Forma:SolidPeso molecular:418.57Ref: TM-T0687
10mg40,00€1mL*10mM (DMSO)44,00€25mg55,00€50mg65,00€100mg101,00€200mg133,00€500mg256,00€
