Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1523 produtos de "Autofagia"
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Retinoic acid
CAS:Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Fórmula:C20H28O2Pureza:97.21% - 99.60%Cor e Forma:Yellow-Orange PowderPeso molecular:300.44Erythromycin ethylsuccinate
CAS:Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.Fórmula:C43H75NO16Pureza:77% - 98%Cor e Forma:White Or Slightly Yellow Crystalline Powder White To Yellowish Crystalline SolidPeso molecular:862.05Metyrapone
CAS:Metyrapone (NSC-25265) blocks steroid 11β-monooxygenase, used to diagnose Cushing's syndrome.Fórmula:C14H14N2OPureza:99.03% - ≥95%Cor e Forma:Crystals From Ether & Pentane SolidPeso molecular:226.27Telmisartan
CAS:Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.Fórmula:C33H30N4O2Pureza:99.88% - 99.97%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:514.62Pictilisib dimethanesulfonate
CAS:Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) andFórmula:C25H35N7O9S4Pureza:99.63%Cor e Forma:SolidPeso molecular:705.85Nicardipine hydrochloride
CAS:Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.Fórmula:C26H30ClN3O6Pureza:99.58% - 99.89%Cor e Forma:Yellow SolidPeso molecular:515.99Vancomycin hydrochloride
CAS:Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!Fórmula:C66H76Cl3N9O24Pureza:97.20% - 99.19%Cor e Forma:Off White PowderPeso molecular:1485.71Stavudine
CAS:Stavudine (BMY-27857), a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.Fórmula:C10H12N2O4Pureza:99.01% - 99.88%Cor e Forma:White PowderPeso molecular:224.21Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Fórmula:C14H24Cl2N2O3Pureza:99.58%Cor e Forma:Crystalline SolidPeso molecular:339.258ZX-29
CAS:ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.Fórmula:C23H28ClN7O3SPureza:98.32%Cor e Forma:SolidPeso molecular:518.03Ref: TM-T13416
1mg96,00€5mg219,00€1mL*10mM (DMSO)250,00€10mg344,00€25mg587,00€50mg803,00€100mg1.063,00€200mg1.431,00€Sulfadoxine
CAS:Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarialFórmula:C12H14N4O4SPureza:99.67%Cor e Forma:White Or White Crystalline PowderPeso molecular:310.33LG-100064
CAS:LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Fórmula:C23H26O3Pureza:98.65%Cor e Forma:SolidPeso molecular:350.45Ref: TM-T11844
2mg44,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg92,00€25mg164,00€50mg235,00€100mg350,00€200mg515,00€Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Fórmula:C20H17FO3SPureza:99.09% - 99.15%Cor e Forma:Yellow SolidPeso molecular:356.41Felodipine
CAS:Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.Fórmula:C18H19Cl2NO4Pureza:99.91%Cor e Forma:SolidPeso molecular:384.25Ref: TM-T0145
2mg34,00€5mg50,00€1mL*10mM (DMSO)54,00€10mg67,00€25mg96,00€50mg123,00€100mg168,00€500mg409,00€Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Fórmula:C27H29NO11·HClPureza:98% - 99.52%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99SP-8356
CAS:SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.Fórmula:C18H20O4Pureza:98.24%Cor e Forma:SolidPeso molecular:300.35Ref: TM-T12981
1mg66,00€5mg147,00€1mL*10mM (DMSO)166,00€10mg225,00€25mg425,00€50mg577,00€100mg772,00€200mg1.044,00€Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Fórmula:C8H12BrNO3Pureza:98.22% - 99.88%Cor e Forma:Beige To Brown Fine Crystalline PowderPeso molecular:250.09Erlotinib hydrochloride
CAS:Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Fórmula:C22H23N3O4·HClPureza:99.78% - 99.85%Cor e Forma:White Or Off-White PowderPeso molecular:429.90Ursolic acid
CAS:Ursolic acid (Prunol) is a natural pentacyclic triterpene carboxylic acid. Ursolic acid has anti-tumor and anti-inflammatory effects. Cost-effective and quality-assured.Fórmula:C30H48O3Pureza:99.7% - 99.81%Cor e Forma:Platelets From Alcohol SolidPeso molecular:456.70Honokiol
CAS:Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.Fórmula:C18H18O2Pureza:99.65% - 99.94%Cor e Forma:Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter TastePeso molecular:266.33Elexacaftor
CAS:Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.Fórmula:C26H34F3N7O4SPureza:98.87% - 99.87%Cor e Forma:SolidPeso molecular:597.65Ref: TM-T14935
1mg93,00€2mg130,00€5mg230,00€1mL*10mM (DMSO)304,00€10mg371,00€25mg730,00€50mg1.018,00€100mg1.369,00€Pyrazinamide
CAS:Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amideFórmula:C5H5N3OPureza:99.71% - 99.95%Cor e Forma:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Peso molecular:123.119-ING-41
CAS:9-ING-41 is a glycogen synthase kinase-3 inhibitor.Fórmula:C22H13FN2O5Pureza:99.32%Cor e Forma:SolidPeso molecular:404.35Ref: TM-T14066
1mg50,00€2mg66,00€5mg94,00€1mL*10mM (DMSO)110,00€10mg155,00€25mg309,00€50mg447,00€100mg667,00€Bicalutamide
CAS:Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting theFórmula:C18H14F4N2O4SPureza:98% - 99.87%Cor e Forma:Off-White Crystalline SolidPeso molecular:430.37Amiodarone hydrochloride
CAS:Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.Fórmula:C25H29I2NO3·HClPureza:99.82% - ≥95%Cor e Forma:White To Cream Crystalline PowderPeso molecular:681.78Itraconazole
CAS:Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Fórmula:C35H38Cl2N8O4Pureza:98% - 99.90%Cor e Forma:Off-White Crystalline SolidPeso molecular:705.63Lomustine
CAS:Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Fórmula:C9H16ClN3O2Pureza:98.36% - 99.44%Cor e Forma:Solid SolidPeso molecular:233.7Theophylline
CAS:Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and centralFórmula:C7H8N4O2Pureza:99.65% - 99.98%Cor e Forma:White Solid PowderPeso molecular:180.16Hydroxyurea
CAS:Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.Fórmula:CH4N2O2Pureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:76.05Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFórmula:C21H18O11Pureza:90.08% - 99.32%Cor e Forma:Yellow PowderPeso molecular:446.36Ref: TM-T2775
50mg34,00€100mg49,00€200mg49,00€1mL*10mM (DMSO)50,00€500mg55,00€1g80,00€2g102,00€5g152,00€Glibenclamide
CAS:Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Cor e Forma:SolidPeso molecular:494.00Rimantadine hydrochloride
CAS:Rimantadine hydrochloride (Meradane) is an RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.Fórmula:C12H21N·HClPureza:99.47% - 99.85%Cor e Forma:White Crystalline SolidPeso molecular:215.76Tioconazole
CAS:Tioconazole (Vagistat) is a synthetic imidazole derivative, inhibits cell wall synthesis by inhibiting the biosynthesis of ergosterol or other sterols.Fórmula:C16H13Cl3N2OSPureza:99.57%Cor e Forma:SolidPeso molecular:387.71Tranexamic acid
CAS:Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.Fórmula:C8H15NO2Pureza:99.64% - 99.79%Cor e Forma:White Crystalline PowderPeso molecular:157.21Colistin sulfate
CAS:Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.Fórmula:C53H100N16O17SPureza:98%Cor e Forma:PowderPeso molecular:1253.51AKOS037652256
CAS:AKOS037652256 modulates TRPML, treating TRPML-linked diseases like lysosomal disorders, muscular dystrophy, neurodegeneration, and oxidative stress.Fórmula:C24H26ClFN4O4S2Pureza:99.22%Cor e Forma:SolidPeso molecular:553.07MLi-2
CAS:MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.Fórmula:C21H25N5O2Pureza:98.96%Cor e Forma:SolidPeso molecular:379.46Ref: TM-T16115
1mg55,00€2mg84,00€5mg126,00€1mL*10mM (DMSO)135,00€10mg178,00€25mg409,00€50mg618,00€100mg880,00€Adapalene
CAS:Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.Fórmula:C28H28O3Pureza:99.53% - 99.76%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:412.52Loperamide hydrochloride
CAS:Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.Fórmula:C29H34Cl2N2O2Pureza:99.91% - >99.99%Cor e Forma:Crystals Practically Insoluble In WaterPeso molecular:513.50Simvastatin
CAS:Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity.Fórmula:C25H38O5Pureza:98.54% - 99.13%Cor e Forma:SolidPeso molecular:418.57Ref: TM-T0687
10mg40,00€1mL*10mM (DMSO)44,00€25mg55,00€50mg65,00€100mg101,00€200mg133,00€500mg256,00€Spironolactone
CAS:Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.Fórmula:C24H32O4SPureza:99.87%Cor e Forma:White PowderPeso molecular:416.57Crustecdysone
CAS:Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.
Fórmula:C27H44O7Pureza:99.06% - 99.67%Cor e Forma:Canary Yellow Fine PowderPeso molecular:480.63Paclitaxel
CAS:Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.
Fórmula:C47H51NO14Pureza:98% - 99.92%Cor e Forma:White PowderPeso molecular:853.91Ponatinib Hydrochloride
CAS:Ponatinib Hydrochloride (AP-24534 Hydrochloride) is a hydrochloride of ponatinib.Fórmula:C29H28ClF3N6OPureza:99.88%Cor e Forma:SolidPeso molecular:569.02Chenodeoxycholic acid
CAS:Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!
Fórmula:C24H40O4Pureza:99.70% - 99.93%Cor e Forma:White - Almost White Solid PowderPeso molecular:392.57Sulfanilamide
CAS:Sulfanilamide (UK-124) can competitively inhibit bacterial enzyme dihydropteroate synthetase with IC50 of 320 μM.Fórmula:C6H8N2O2SPureza:97.4% - 99.76%Cor e Forma:White To Yellowish Crystalline PowderPeso molecular:172.20Naproxen sodium
CAS:Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.Fórmula:C14H13NaO3Pureza:99.68% - 99.93%Cor e Forma:White PowderPeso molecular:252.24Vorinostat
CAS:Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.Fórmula:C14H20N2O3Pureza:99.47% - 99.65%Cor e Forma:White Crystalline SolidPeso molecular:264.32Lapatinib Ditosylate
CAS:Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Cor e Forma:Yellow SolidPeso molecular:925.46Oxybenzone
CAS:Oxybenzone (Eusolex 4360) is an organic compound used in sunscreens. It is a derivative of benzophenone.Fórmula:C14H12O3Pureza:99.70%Cor e Forma:Colorless Crystals Physical Description White To Off-White Or Light Yellow Powder (Ntp 1992)Peso molecular:228.24
