Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1424 produtos de "Autofagia"
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Metyrapone
CAS:<p>Metyrapone (NSC-25265) blocks steroid 11β-monooxygenase, used to diagnose Cushing's syndrome.</p>Fórmula:C14H14N2OPureza:99.03% - ≥95%Cor e Forma:Crystals From Ether & Pentane SolidPeso molecular:226.27Myricetin
CAS:<p>Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic and antioxidant activities. Cost-effective and quality-assured.</p>Fórmula:C15H10O8Pureza:97.92% - 99.85%Cor e Forma:Yellow Needles From Dilute Alcohol SolidPeso molecular:318.24Retinoic acid
CAS:<p>Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.</p>Fórmula:C20H28O2Pureza:97.21% - 99.6%Cor e Forma:Yellow-Orange PowderPeso molecular:300.44Telmisartan
CAS:<p>Telmisartan (BIBR 277) is an Angiotensin 2 Receptor Blocker. The mechanism of action of telmisartan is as an Angiotensin 2 Receptor Antagonist.</p>Fórmula:C33H30N4O2Pureza:99.88% - 99.97%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:514.62Pictilisib dimethanesulfonate
CAS:<p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>Fórmula:C25H35N7O9S4Pureza:99.63%Cor e Forma:SolidPeso molecular:705.85Berberine chloride
CAS:<p>Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae, and used orally for various fungal and parasitic infections.</p>Fórmula:C20H18ClNO4Pureza:99.47% - 99.93%Cor e Forma:Yellow Crystalline PowderPeso molecular:371.8Ciclopirox
CAS:<p>Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.</p>Fórmula:C12H17NO2Pureza:97.72% - 99.78%Cor e Forma:SolidPeso molecular:207.27Vancomycin hydrochloride
CAS:<p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>Fórmula:C66H76Cl3N9O24Pureza:97.20% - 99.19%Cor e Forma:Off White PowderPeso molecular:1485.71Ancitabine hydrochloride
CAS:<p>Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity.</p>Fórmula:C9H12ClN3O4Pureza:99.02% - 99.37%Cor e Forma:White SolidPeso molecular:261.66Irinotecan Hydrochloride
CAS:<p>Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.</p>Fórmula:C33H39ClN4O6Pureza:98% - 99.94%Cor e Forma:Yellow Crystalline PowderPeso molecular:623.14ZX-29
CAS:<p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>Fórmula:C23H28ClN7O3SPureza:98.32%Cor e Forma:SolidPeso molecular:518.03Trimetazidine dihydrochloride
CAS:<p>Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.</p>Fórmula:C14H24Cl2N2O3Pureza:99.58%Cor e Forma:Crystalline SolidPeso molecular:339.258LG-100064
CAS:<p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>Fórmula:C23H26O3Pureza:98.65%Cor e Forma:SolidPeso molecular:350.45Felodipine
CAS:<p>Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.</p>Fórmula:C18H19Cl2NO4Pureza:99.91%Cor e Forma:SolidPeso molecular:384.25Isoliquiritigenin
CAS:<p>Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.</p>Fórmula:C15H12O4Pureza:97.61% - 99.44%Cor e Forma:PowderPeso molecular:256.25Carvedilol phosphate hemihydrate
CAS:<p>Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent.</p>Fórmula:C24H26N2O4·5H2O·H3O4PPureza:99.24% - 99.98%Cor e Forma:SolidPeso molecular:513.49Doxorubicin hydrochloride
CAS:<p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>Fórmula:C27H29NO11·HClPureza:98% - 99.52%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99Erlotinib hydrochloride
CAS:<p>Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Fórmula:C22H23N3O4·HClPureza:99.78% - 99.85%Cor e Forma:White Or Off-White PowderPeso molecular:429.9Oxidopamine hydrobromide
CAS:<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Fórmula:C8H12BrNO3Pureza:98.22% - 99.88%Cor e Forma:Beige To Brown Fine Crystalline PowderPeso molecular:250.09Elexacaftor
CAS:<p>Elexacaftor (VX-445) is a cystic fibrosis transmembrane conductance regulator (CFTR) corrector.Cost-effective and quality-assured.</p>Fórmula:C26H34F3N7O4SPureza:98.87% - 99.87%Cor e Forma:SolidPeso molecular:597.659-ING-41
CAS:<p>9-ING-41 is a glycogen synthase kinase-3 inhibitor.</p>Fórmula:C22H13FN2O5Pureza:99.32%Cor e Forma:SolidPeso molecular:404.35Aceglutamide
CAS:<p>Aceglutamide (N2-Acetylglutamine) is an acetyl derivative of the amino acid L-glutamine, used to improve memory.</p>Fórmula:C7H12N2O4Pureza:99.56% - 99.86%Cor e Forma:SolidPeso molecular:188.18Pyrazinamide
CAS:<p>Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide</p>Fórmula:C5H5N3OPureza:99.71% - 99.9%Cor e Forma:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Peso molecular:123.11Mogamulizumab
CAS:<p>Mogamulizumab is a monoclonal antibody targeting CC chemokine receptor 4 with anticancer effects, used in ATLL and CTCL studies.</p>Pureza:SDS-PAGE:97.3%;SEC-HPLC:99.4%Cor e Forma:LiquidPeso molecular:146.43 kDaVitamin B3-d4
CAS:<p>Vitamin B3-d4 (Nicotinic acid-(ring-d4)) is a deuterated substitute for Niacin and can be used to track Niacin metabolism in vivo.</p>Fórmula:C6HD4NO2Pureza:99.86%Cor e Forma:SolidPeso molecular:127.13Amiodarone hydrochloride
CAS:<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Fórmula:C25H29I2NO3·HClPureza:99.82% - ≥95%Cor e Forma:White To Cream Crystalline PowderPeso molecular:681.78Itraconazole
CAS:<p>Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.</p>Fórmula:C35H38Cl2N8O4Pureza:98% - 99.90%Cor e Forma:Off-White Crystalline SolidPeso molecular:705.63Lomustine
CAS:<p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>Fórmula:C9H16ClN3O2Pureza:98.36% - 99.44%Cor e Forma:Solid SolidPeso molecular:233.7Eldelumab
CAS:<p>Eldelumab (BMS-936557) is an anti-IP-10 IgG 1 monoclonal antibody.Eldelumab has anti-inflammatory activity and is used to study rheumatoid arthritis.</p>Pureza:95%Cor e Forma:LiquidAcesulfame Potassium
CAS:<p>Acesulfame potassium is a non-nutritive sweetener.</p>Fórmula:C4H4KNO4SPureza:99.65%Cor e Forma:White Solid CrystallinePeso molecular:201.24Hydroxyurea
CAS:<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Fórmula:CH4N2O2Pureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:76.05Baicalin
CAS:<p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>Fórmula:C21H18O11Pureza:90.08% - 99.32%Cor e Forma:Yellow PowderPeso molecular:446.36Glibenclamide
CAS:<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Fórmula:C23H28ClN3O5SPureza:99.05% - 99.75%Cor e Forma:SolidPeso molecular:494.00Tranexamic acid
CAS:<p>Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.</p>Fórmula:C8H15NO2Pureza:99.64% - 99.79%Cor e Forma:White Crystalline PowderPeso molecular:157.21Sulfacetamide sodium monohydrate
CAS:<p>Sulfacetamide sodium monohydrate is a sulfonamide antibiotic. It has been investigated for the treatment of rosacea and pityriasis versicolor.</p>Fórmula:C8H9N2NaO3S·H2OPureza:99.92%Cor e Forma:White Crystalline PowderPeso molecular:254.2Colistin sulfate
CAS:<p>Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.</p>Fórmula:C53H100N16O17SPureza:98%Cor e Forma:PowderPeso molecular:1253.51Sulfanitran
CAS:<p>Sulfanitran is a sulfonamide antibiotic used in the poultry industry.</p>Fórmula:C14H13N3O5SPureza:98.3% - 99.60%Cor e Forma:SolidPeso molecular:335.34Adapalene
CAS:<p>Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.</p>Fórmula:C28H28O3Pureza:99.53% - 99.76%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:412.52MLi-2
CAS:<p>MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.</p>Fórmula:C21H25N5O2Pureza:98.96%Cor e Forma:SolidPeso molecular:379.46Loperamide hydrochloride
CAS:<p>Loperamide hydrochloride (ADL 2-1294) is a synthetic, piperidine derivative and opioid agonist with antidiarrheal activity.</p>Fórmula:C29H34Cl2N2O2Pureza:99.91% - >99.99%Cor e Forma:Crystals Practically Insoluble In WaterPeso molecular:513.50Spironolactone
CAS:<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Fórmula:C24H32O4SPureza:99.87%Cor e Forma:White PowderPeso molecular:416.57Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Fórmula:C15H24N2OPureza:97.16% - >99.99%Cor e Forma:SolidPeso molecular:248.36Crustecdysone
CAS:<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Fórmula:C27H44O7Pureza:99.06% - 99.67%Cor e Forma:Canary Yellow Fine PowderPeso molecular:480.63Paclitaxel
CAS:<p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>Fórmula:C47H51NO14Pureza:98% - 99.92%Cor e Forma:White PowderPeso molecular:853.91Chenodeoxycholic acid
CAS:<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Fórmula:C24H40O4Pureza:99.70% - 99.93%Cor e Forma:White - Almost White Solid PowderPeso molecular:392.57Pemetrexed disodium
CAS:<p>Pemetrexed disodium treats lung cancer/mesothelioma; may cause moderate serum enzyme elevation, rarely acute liver injury.</p>Fórmula:C20H19N5Na2O6Pureza:99.29% - 99.49%Cor e Forma:Crystalline SolidPeso molecular:471.37Naproxen sodium
CAS:<p>Naproxen sodium (Anaprox) is a COX inhibitor for COX-1 and COX-2 with analgesic and antipyretic properties.</p>Fórmula:C14H13NaO3Pureza:99.68% - 99.79%Cor e Forma:White PowderPeso molecular:252.24Vorinostat
CAS:<p>Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.</p>Fórmula:C14H20N2O3Pureza:99.47% - 99.65%Cor e Forma:White Crystalline SolidPeso molecular:264.32Sulfisoxazole
CAS:<p>Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.</p>Fórmula:C11H13N3O3SPureza:99.87% - 99.98%Cor e Forma:White To Cream PowderPeso molecular:267.30Niacin
CAS:<p>Niacin is a water-soluble B vitamin with antihyperlipidemic effects, found in food and converted to niacinamide for coenzyme activity.</p>Fórmula:C6H5NO2Pureza:99.05% - 99.72%Cor e Forma:White Solid PowderPeso molecular:123.11
