Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1483 produtos de "Autofagia"
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PD146176
CAS:<p>PD146176 (NSC-168807) is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM.</p>Fórmula:C15H11NSPureza:98.00%Cor e Forma:SolidPeso molecular:237.32PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Fórmula:C19H16N4O3Pureza:97.79% - 99.3%Cor e Forma:SolidPeso molecular:348.36Fasudil hydrochloride hydrate
CAS:Fasudil HCl hydrate is a ROCK inhibitor that hinders mature CCM development and lowers portal pressure in cirrhotic rats.Fórmula:C28H38Cl2N6O5S2Cor e Forma:SolidPeso molecular:673.67Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Fórmula:C23H28O7Pureza:99.14% - 99.95%Cor e Forma:SolidPeso molecular:416.46Brefeldin A
CAS:Brefeldin A (Cyanein) belongs to the class of macrolide antibiotics and is an ATPase inhibitor (IC50=0.2 μM).Fórmula:C16H24O4Pureza:96.45% - 99.89%Cor e Forma:White SolidPeso molecular:280.36Bicyclol
CAS:<p>Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.</p>Fórmula:C19H18O9Pureza:99.64% - 99.85%Cor e Forma:SolidPeso molecular:390.34Torin 1
CAS:<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Fórmula:C35H28F3N5O2Pureza:98.3% - 99.33%Cor e Forma:SolidPeso molecular:607.62Sanguinarine
CAS:Sanguinarine (Pseudochelerythrine) is a specific inhibitor of Rac1b with anti-microbial, anti-oxidant and anti-inflammatory properties.Fórmula:C20H14NO4Pureza:99.04% - 99.76%Cor e Forma:SolidPeso molecular:332.33L-779450
CAS:L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.Fórmula:C20H14ClN3OPureza:≥95%Cor e Forma:SolidPeso molecular:347.8Salbutamol hemisulfate
CAS:Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.Fórmula:C13H21NO3H2O4SPureza:99.35%Cor e Forma:White Or Almost White Odourless PowderPeso molecular:576.70LRRK2-IN-1
CAS:LRRK2-IN-1 is an effective and selective LRRK2 inhibitor.Fórmula:C31H38N8O3Pureza:98% - 98.82%Cor e Forma:SolidPeso molecular:570.69FIPI HCl
CAS:FIPI: Selective phospholipase D inhibitor, blocks mercury-induced lipid signals, protects aortic cells.Fórmula:C23H25ClFN5O2Cor e Forma:SolidPeso molecular:457.93Lapatinib tosylate
CAS:Lapatinib tosylate (GW572016) is an oral ErbB-2/EGFR inhibitor with IC50s of 10.2 nM (EGFR) & 9.8 nM (ErbB-2).Fórmula:C36H34ClFN4O7S2Cor e Forma:SolidPeso molecular:753.26ABT-737
CAS:ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.Fórmula:C42H45ClN6O5S2Pureza:98.15% - >99.99%Cor e Forma:SolidPeso molecular:813.43Idarubicin
CAS:Idarubicin, a potent oral anthracycline, halts DNA/RNA replication and synthesis, damages DNA, and inhibits microbial growth.Fórmula:C26H27NO9Cor e Forma:SolidPeso molecular:497.49FERULIC ACID METHYL ESTER
CAS:FERULIC ACID METHYL ESTER (Methyl ferulate) is a hydroxycinnamic acid that is abundant in plants. FERULIC ACID METHYL ESTER has antioxidant activities.Fórmula:C11H12O4Pureza:99.66% - 99.95%Cor e Forma:SolidPeso molecular:208.21Calcimycin
CAS:<p>Calcimycin (A-23187) is a polyether antibiotic that transports Ca²⁺, uncouples phosphorylation, and inhibits ATPase in mitochondria.</p>Fórmula:C29H37N3O6Pureza:98%Cor e Forma:SolidPeso molecular:523.62MRT68921 HCl
CAS:<p>MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM, respectively).</p>Fórmula:C25H34N6O·HClPureza:99.86% - 99.98%Cor e Forma:SolidPeso molecular:471.04Dinoprost tromethamine salt
CAS:Dinoprost tromethamine salt (PGF2α THAM) is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.Fórmula:C24H45NO8Pureza:99.73%Cor e Forma:Natural Form Crystals SolidPeso molecular:475.62Oprozomib
CAS:Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.Fórmula:C25H32N4O7SPureza:98% - 99.87%Cor e Forma:SolidPeso molecular:532.61
