Receptor Endotelina
Os receptores de endotelina são GPCRs que mediam os efeitos das endotelinas, potentes peptídeos vasoconstritores que desempenham um papel significativo na regulação do tônus vascular, controle da pressão arterial e proliferação celular. Antagonistas dos receptores de endotelina são usados no tratamento de condições como hipertensão arterial pulmonar e insuficiência cardíaca. Esses receptores também são alvos importantes na pesquisa sobre doenças cardiovasculares e câncer. Na CymitQuimica, oferecemos uma seleção de moduladores de receptores de endotelina de alta qualidade para apoiar sua pesquisa em biologia cardiovascular, oncologia e fisiologia vascular.
Foram encontrados 76 produtos de "Receptor Endotelina"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Enrasentan
CAS:<p>Enrasentan (sb-217242) is a mixed antagonist of ET(A) and ET(B) receptors that reduces blood pressure and protects myocardial function.</p>Fórmula:C29H30O8Pureza:97.9% - 98.39%Cor e Forma:SolidPeso molecular:506.54Sulfisoxazole
CAS:<p>Sulfisoxazole: a short-acting antibacterial targeting gram-positive/negative bacteria and inhibits breast cancer exosome by affecting endothelin receptor A.</p>Fórmula:C11H13N3O3SPureza:99.87% - 99.98%Cor e Forma:White To Cream PowderPeso molecular:267.30Endothelin 1 (swine, human), Alexa Fluor 488-labeled
<p>Synthetic human/swine Endothelin 1 peptide, tagged with Alexa Fluor 488, acts as a strong vasoconstrictor via ET A/B receptors.</p>Cor e Forma:SolidPeso molecular:2848.4[Lys4] Sarafotoxin S6c
CAS:<p>[Lys4] Sarafotoxin S6c: potent partial endothelin receptor agonist; causes pig coronary contraction, EC50=1.5 nM.</p>Fórmula:C105H153N27O36S5Cor e Forma:SolidPeso molecular:2529.82IRL-1620
CAS:<p>IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).</p>Fórmula:C86H117N17O27Pureza:98%Cor e Forma:SolidPeso molecular:1820.974[Ala2] Endothelin-3, human
CAS:<p>[Ala2] Endothelin-3, a linear ET-3 analog with Ala replacing Cys, stimulates endothelial cell migration.</p>Fórmula:C120H166N26O32S4Cor e Forma:SolidPeso molecular:2613.02Sarafotoxin S6b
CAS:<p>non-selective endothelin receptor agonist</p>Fórmula:C110H163N27O34S5Pureza:98%Cor e Forma:SolidPeso molecular:2567.96Nebentan
CAS:<p>Nebentan (YM598) is an oral, selective ETA antagonist; Ki: 0.697 nM (ETA), 569 nM (ETB); may slow cor pulmonale, myocardial infarction.</p>Fórmula:C24H21N5O5SCor e Forma:SolidPeso molecular:491.52Sarafotoxin S6a
CAS:<p>Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.</p>Fórmula:C105H156N28O34S5Pureza:98%Cor e Forma:SolidPeso molecular:2514.85Atrial Natriuretic Peptide (ANP) (1-28), rat
CAS:<p>Atrial Natriuretic Peptide (1-28), rat is the major circulating form of ANP in rats.</p>Fórmula:C128H205N45O39S2Pureza:98%Cor e Forma:SolidPeso molecular:3062.41ACT-373898
CAS:<p>ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ETA) and ETBdual antagonist macitentan .1</p>Fórmula:C15H17BrN4O5SCor e Forma:SolidPeso molecular:445.29Sarafotoxin S6c
CAS:<p>Highly selective ETB endothelin receptor agonist (Ki values are 0.29 and 28000 nM at ETB and ETA receptors respectively).</p>Fórmula:C103H147N27O37S5Pureza:98%Cor e Forma:SolidPeso molecular:2516IRL-1038
CAS:<p>ETB endothelin receptor antagonist</p>Fórmula:C68H92N14O15S2Pureza:98%Cor e Forma:SolidPeso molecular:1409.67PD 142893
CAS:<p>PD 142893 is a functional endothelin-stimulated vasoconstriction antagonist.</p>Fórmula:C50H65N7O10Pureza:98%Cor e Forma:SolidPeso molecular:924.09[Ala1,3,11,15]-Endothelin
CAS:<p>Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).</p>Fórmula:C109H163N25O32SPureza:98%Cor e Forma:SolidPeso molecular:2368BQ-123 TFA
<p>BQ-123 TFA: Potent ETA antagonist, IC50 = 7.3 nM, Ki = 25 nM, inhibits ET-1 cell proliferation, lowers rat BP.</p>Fórmula:C33H43F3N6O9Cor e Forma:SolidPeso molecular:724.72IRL-3630
CAS:<p>IRL 3460 is an enantiomer.</p>Fórmula:C31H40N4O6SPureza:98%Cor e Forma:SolidPeso molecular:596.74SB234551
CAS:<p>SB234551 is a selective antagonist of endothelin ETA receptor.</p>Fórmula:C34H34N2O9Cor e Forma:SolidPeso molecular:614.64Atrial natriuretic factor (1-28) (rat) TFA
<p>ANP (1-28), rat (TFA) inhibits Ang II-induced endothelin-1 secretion; main circulating ANP form in rats.</p>Fórmula:C130H206N45F3O41S2Pureza:98%Cor e Forma:SolidPeso molecular:3176.43Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate
CAS:<p>Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate is an NPR-A agonist and ANP hormone. Carperitide increases cGMP levels and reduces the heart's workload.</p>Fórmula:C129H207N45O41S3Pureza:99.78%Cor e Forma:SoildPeso molecular:3140.5
![[Lys4] Sarafotoxin S6c](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76302.webp&w=3840&q=75)
![[Ala2] Endothelin-3, human](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76305.webp&w=3840&q=75)
![[Ala1,3,11,15]-Endothelin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP2099.webp&w=3840&q=75)
