gsk-3
Os inibidores da GSK-3 são compostos que alvo a Glicogênio Sintase Quinase 3 (GSK-3), uma enzima envolvida em numerosos processos celulares, incluindo o metabolismo do glicogênio, a transcrição genética e a proliferação celular. A GSK-3 está implicada em várias doenças, como diabetes, distúrbios neurodegenerativos e câncer. Os inibidores da GSK-3 são ferramentas importantes para explorar essas vias e desenvolver potenciais terapias. Na CymitQuimica, oferecemos inibidores da GSK-3 para apoiar sua pesquisa em doenças metabólicas, neurobiologia e oncologia.
Foram encontrados 112 produtos de "gsk-3"
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GSK-3 inhibitor 3
CAS:<p>GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectively</p>Fórmula:C23H15FN6OPureza:99.89%Cor e Forma:SoildPeso molecular:410.4Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Cor e Forma:Odour Solid2B-(SP)
CAS:<p>Selective phosphopeptide substrate for glycogen synthase kinase-3 (GSK-3)</p>Fórmula:C71H123N26O29PPureza:98%Cor e Forma:SolidPeso molecular:1835.87MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Fórmula:C17H12BrN3O2Pureza:99.64%Cor e Forma:SolidPeso molecular:370.2GSK-3β inhibitor 21
<p>GSK-3β Inhibitor21 (compound 44) is an ATP-competitive inhibitor of GSK-3β with an IC50 value of 6.06 µM, characterized by its ability to inhibit tau phosphorylation and prevent amyloid protein aggregation. This compound is utilized in the research of Alzheimer's disease.</p>Cor e Forma:Odour SolidFRATide
CAS:<p>FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.</p>Fórmula:C55H102N2O2Cor e Forma:SolidPeso molecular:823.433Phospho-Glycogen Synthase Peptide-2(substrate)
CAS:<p>Phospho-Glycogen Synthase Peptide-2 is a GSK-3 substrate, useful for serine kinase affinity purification.</p>Fórmula:C123H191N40O48PCor e Forma:SolidPeso molecular:3029.087CHIR-98023
CAS:<p>CHIR-98023 is a bio-active chemical.</p>Fórmula:C20H16Cl2N8O2Cor e Forma:SolidPeso molecular:471.30GSK3a-IN-38
CAS:<p>GSK3a-IN-38 is a novel small molecule compound that has inhibitory effects on GSK-3a.</p>Fórmula:C18H20N4OPureza:99.75%Cor e Forma:SoildPeso molecular:308.38GSK3β/mTOR modulator 1
<p>GSK3β/mTOR modulator 1 (derivative 2) is an agent that modulates the GSK3β/mTOR signaling pathway. It is applicable in research related to acute lung injury (ALI) and inflammation.</p>Fórmula:C19H28O5Cor e Forma:SolidPeso molecular:336.19367Ceftriaxone Sodium
CAS:<p>Ceftriaxone Sodium is a sporotaxin antibiotic that inhibits GSK3β and Aurora B. It is used in the study of sepsis and infective endocarditis.</p>Fórmula:C18H17N8NaO7S3Cor e Forma:SolidPeso molecular:576.562BIO-acetoxime
CAS:<p>BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.</p>Fórmula:C18H12BrN3O3Pureza:97.15%Cor e Forma:SolidPeso molecular:398.21Bikinin
CAS:<p>Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.</p>Fórmula:C9H9BrN2O3Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:273.08SB 415286
CAS:<p>SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.</p>Fórmula:C16H10ClN3O5Pureza:99.55%Cor e Forma:SolidPeso molecular:359.72VP3.15 dihydrobromide
CAS:<p>VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.</p>Fórmula:C20H24Br2N4OSPureza:99.67% - ≥95%Cor e Forma:SolidPeso molecular:528.3Indirubin-3′-oxime
CAS:<p>Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.</p>Fórmula:C16H11N3O2Pureza:98.34%Cor e Forma:SolidPeso molecular:277.28TDZD-8
CAS:<p>TDZD-8 (NP 01139) is an inhibitor of GSK-3β, with an IC50 of 2 μM; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.</p>Fórmula:C10H10N2O2SPureza:97.13% - 99.61%Cor e Forma:White SolidPeso molecular:222.26AZD1080
CAS:<p>AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.</p>Fórmula:C19H18N4O2Pureza:97.72% - 99.75%Cor e Forma:SolidPeso molecular:334.37GSK-3β inhibitor 10
CAS:<p>GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.</p>Fórmula:C12H12N2O3SPureza:98.06%Cor e Forma:SolidPeso molecular:264.3CP21R7
CAS:<p>CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.</p>Fórmula:C19H15N3O2Pureza:96.14% - 99.16%Cor e Forma:SolidPeso molecular:317.34
