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AMPK

AMPK

Os inibidores de AMPK são compostos que inibem a Quinase Ativada por AMP (AMPK), uma enzima que desempenha um papel crucial na homeostase energética celular. A AMPK é ativada em resposta a baixos níveis de energia nas células e ajuda a regular processos como a captação de glicose, a oxidação de ácidos graxos e a biogênese mitocondrial. Inibir a AMPK é importante para estudar seu papel em doenças metabólicas, câncer e envelhecimento. Na CymitQuimica, oferecemos uma gama de inibidores de AMPK para apoiar sua pesquisa em metabolismo, oncologia e doenças relacionadas ao envelhecimento.

Foram encontrados 168 produtos de "AMPK"

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  • Metformin hydrochloride

    CAS:
    Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.
    Fórmula:C4H12ClN5
    Pureza:97.53% - 99.97%
    Cor e Forma:White Or Almost White Crystals Solid Crystalline
    Peso molecular:165.63
  • Danthron

    CAS:
    Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.
    Fórmula:C14H8O4
    Pureza:99.51% - 99.97%
    Cor e Forma:Red Or Red-Yellow Needles Or Leaves (From Alcohol) Physical Description Orange Crystalline Powder Almost Odorless And Tasteless (Ntp 1992)
    Peso molecular:240.21
  • Urolithin B

    CAS:
    Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical
    Fórmula:C13H8O3
    Pureza:99.45%
    Cor e Forma:Solid
    Peso molecular:212.2
  • Chitosan oligosaccharide

    CAS:
    Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine.
    Fórmula:C12H24N2O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:340.327
  • MT 63-78

    CAS:
    <p>MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).</p>
    Fórmula:C21H14N2O2
    Pureza:97.11%
    Cor e Forma:Solid
    Peso molecular:326.35
  • AICAR

    CAS:
    AICAR (Acadesine) is an AMPK activator, metabolic regulation, muscle function regulation, anti-cancer effect, neuroprotection. High-Quality, Low-Cost!
    Fórmula:C9H14N4O5
    Pureza:98.00% - ≥95%
    Cor e Forma:Solid
    Peso molecular:258.23
  • Doxorubicin hydrochloride

    CAS:
    Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).
    Fórmula:C27H29NO11·HCl
    Pureza:98% - 99.52%
    Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
    Peso molecular:579.99
  • Miglitol

    CAS:
    Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.
    Fórmula:C8H17NO5
    Pureza:99.75% - 99.88%
    Cor e Forma:White To Pale-Yellow Powder Solid
    Peso molecular:207.22
  • Mefloquine

    CAS:
    <p>Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.</p>
    Fórmula:C17H16F6N2O
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:378.31
  • PT-1

    CAS:
    <p>PT-1 is an AMPKα1 activator that dose-dependently activates AMPK α1394, α1335, and α2398 and enhances AMPK phosphorylation.</p>
    Fórmula:C23H16ClN3O6S
    Pureza:99.62%
    Cor e Forma:Solid
    Peso molecular:497.91
  • Phenformin hydrochloride

    CAS:
    <p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>
    Fórmula:C10H16ClN5
    Pureza:97.11% - 99.80%
    Cor e Forma:Lactic Acidosis
    Peso molecular:241.72
  • MARK4 inhibitor 1

    CAS:
    MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis.
    Fórmula:C20H18N6O3
    Pureza:97.7%
    Cor e Forma:Solid
    Peso molecular:390.4
  • Flufenamic acid

    CAS:
    <p>Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.</p>
    Fórmula:C14H10F3NO2
    Pureza:98.68%
    Cor e Forma:White To Light Yellow Crystalline Powder
    Peso molecular:281.23
  • MK8722

    CAS:
    MK8722 is an effective and systemic activator of pan-AMPK.
    Fórmula:C24H20ClN3O4
    Pureza:98.08% - 99.8800%
    Cor e Forma:Solid
    Peso molecular:449.89
  • Mefloquine hydrochloride

    CAS:
    Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.
    Fórmula:C17H17ClF6N2O
    Pureza:99% - 99.99%
    Cor e Forma:Off-White To Yellow Solid
    Peso molecular:414.77
  • Tranexamic acid

    CAS:
    <p>Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.</p>
    Fórmula:C8H15NO2
    Pureza:99.64% - 99.79%
    Cor e Forma:White Crystalline Powder
    Peso molecular:157.21
  • Phenformin

    CAS:
    Phenformin: a biguanide with anti-cancer, anti-glycemic effects, inhibits skin tumors, enhances keratinocyte differentiation/apoptosis.
    Fórmula:C10H15N5
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:205.26
  • RMC-7977

    CAS:
    RMC-7977 is a inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with anticancer activity for the study of solid tumors with KRAS G12C mutations.
    Fórmula:C47H60N8O6S
    Pureza:97.11% - 99.86%
    Cor e Forma:Solid
    Peso molecular:865.09
  • NUAK1-IN-2


    <p>NUAK1-IN-2 (Compound 24) is an inhibitor of NUAK1 with an IC50 of 3.162 nM, as well as an inhibitor of CDK2/4/6. It is applicable in research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.</p>
    Fórmula:C24H30N6O
    Cor e Forma:Solid
    Peso molecular:418.535
  • Foenumoside B

    CAS:
    Foenumoside B, a triterpene saponin extracted from Lysimachia foenum-graecum, stimulates AMPK signaling, suppresses PPARγ-induced adipogenesis, and promotes
    Fórmula:C60H96O25
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1217.39