AMPK
Os inibidores de AMPK são compostos que inibem a Quinase Ativada por AMP (AMPK), uma enzima que desempenha um papel crucial na homeostase energética celular. A AMPK é ativada em resposta a baixos níveis de energia nas células e ajuda a regular processos como a captação de glicose, a oxidação de ácidos graxos e a biogênese mitocondrial. Inibir a AMPK é importante para estudar seu papel em doenças metabólicas, câncer e envelhecimento. Na CymitQuimica, oferecemos uma gama de inibidores de AMPK para apoiar sua pesquisa em metabolismo, oncologia e doenças relacionadas ao envelhecimento.
Foram encontrados 163 produtos para "AMPK".
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MT 63-78
CAS:MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).Fórmula:C21H14N2O2Pureza:97.11% - 98.95%Cor e Forma:SolidPeso molecular:326.35Ref: TM-T16156
1mg84,00€5mg160,00€1mL*10mM (DMSO)167,00€10mg260,00€25mg440,00€50mg628,00€100mg872,00€Danthron
CAS:Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.Fórmula:C14H8O4Pureza:99.51% - 99.97%Cor e Forma:Red Or Red-Yellow Needles Or Leaves (From Alcohol) Physical Description Orange Crystalline Powder Almost Odorless And Tasteless (Ntp 1992)Peso molecular:240.21PT-1
CAS:PT-1 is an AMPKα1 activator that dose-dependently activates AMPK α1394, α1335, and α2398 and enhances AMPK phosphorylation.Fórmula:C23H16ClN3O6SPureza:99.62%Cor e Forma:SolidPeso molecular:497.91Metformin hydrochloride
CAS:Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.Fórmula:C4H12ClN5Pureza:97.53% - 99.97%Cor e Forma:White Or Almost White Crystals Solid CrystallinePeso molecular:165.63Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Fórmula:C14H10F3NO2Pureza:98.68%Cor e Forma:White To Light Yellow Crystalline PowderPeso molecular:281.23AICAR
CAS:AICAR (Acadesine) is an AMPK activator, metabolic regulation, muscle function regulation, anti-cancer effect, neuroprotection. High-Quality, Low-Cost!Fórmula:C9H14N4O5Pureza:98.00% - ≥95%Cor e Forma:SolidPeso molecular:258.23RMC-7977
CAS:RMC-7977 is a inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with anticancer activity for the study of solid tumors with KRAS G12C mutations.Fórmula:C47H60N8O6SPureza:97.11% - 99.86%Cor e Forma:SolidPeso molecular:865.09Ref: TM-T81263
1mg231,00€5mg580,00€10mg798,00€1mL*10mM (DMSO)888,00€25mg1.198,00€50mg1.611,00€100mg2.187,00€Mefloquine
CAS:Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor.Fórmula:C17H16F6N2OPureza:99.89%Cor e Forma:SolidPeso molecular:378.31Ref: TM-T0860L
1mg66,00€5mg145,00€1mL*10mM (DMSO)152,00€10mg213,00€25mg356,00€50mg510,00€100mg715,00€200mg964,00€Phenformin
CAS:Phenformin: a biguanide with anti-cancer, anti-glycemic effects, inhibits skin tumors, enhances keratinocyte differentiation/apoptosis.Fórmula:C10H15N5Pureza:99.72%Cor e Forma:SolidPeso molecular:205.26Chitosan oligosaccharide
CAS:Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine.Fórmula:C12H24N2O9Pureza:98%Cor e Forma:SolidPeso molecular:340.327MARK4 inhibitor 1
CAS:MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis.Fórmula:C20H18N6O3Pureza:97.7%Cor e Forma:SolidPeso molecular:390.4Phenformin hydrochloride
CAS:Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.Fórmula:C10H16ClN5Pureza:97.11% - 99.80%Cor e Forma:Lactic AcidosisPeso molecular:241.72MK8722
CAS:MK8722 is an effective and systemic activator of pan-AMPK.Fórmula:C24H20ClN3O4Pureza:98.08% - 99.8800%Cor e Forma:White SolidPeso molecular:449.89Ref: TM-T16099
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg215,00€50mg396,00€100mg585,00€Mefloquine hydrochloride
CAS:Mefloquine hydrochloride (Mefloquin hydrochloride) is a quinoline derivative used for the prevention and therapy of P. falciparum malaria.Fórmula:C17H17ClF6N2OPureza:99% - 99.99%Cor e Forma:Off-White To Yellow SolidPeso molecular:414.77Tranexamic acid
CAS:Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.Fórmula:C8H15NO2Pureza:99.64% - 99.79%Cor e Forma:White Crystalline PowderPeso molecular:157.21Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Fórmula:C27H29NO11·HClPureza:98% - 99.99%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99Miglitol
CAS:Miglitol (BAY1099) is an alpha-Glucosidase Inhibitor with antihyperglycemic activity.Fórmula:C8H17NO5Pureza:99.75% - 99.88%Cor e Forma:White To Pale-Yellow Powder SolidPeso molecular:207.22Urolithin B
CAS:Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropicalFórmula:C13H8O3Pureza:99.45%Cor e Forma:SolidPeso molecular:212.2STO-609 acetate
CAS:STO-609 acetate is selective, cell-permeable inhibitor of Ca2+-calmodulin-dependent protein kinase kinase (Ki: 80/15 ng/ml, for CaM-KKα/KKβ); competes for theFórmula:C19H10N2O3·C2H4O2Pureza:99.75%Cor e Forma:SolidPeso molecular:374.35Antidiabetic agent 7
Antidiabetic agent 7 (Compound 5m) functions as a potent hyperglycemia inhibitor. It effectively stimulates GLUT4 translocation in skeletal muscle cells by activating the AMPK-dependent pathway. Additionally, this compound is capable of reducing blood glucose levels and exhibits favorable pharmacokinetic properties. Antidiabetic agent 7 is suitable for research related to antihyperglycemic treatments.Fórmula:C27H21Cl2N5O3Cor e Forma:SolidPeso molecular:534.39
