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4-O-(b-D-Mannopyranosyl)-D-glucose is a metabolite of D-mannose. It is a bacterial metabolite produced by Streptococcus pneumoniae that has been shown to inhibit the growth of bacteria by binding to the 50S ribosomal subunit. 4-O-(b-D-Mannopyranosyl)-D-glucose inhibits bacterial growth by binding to DNA dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Rifapentine also specifically binds to markers expressed at high levels in Mycobacter

Laminaran is a polysaccharide that co-occurs with fucoidan and alginate in brown seaweeds such as Laminaria digitata, Laminaria cloustoni, Eisenia bicyclis and Thallus laminariae. It is a β-1,3-linked glucan which it is claimed stimulates the immune system in mammals and fish.
The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.

4-Methoxyphenyl 4-O-{4-O-[[2-O-Ac-3-O-[2,4-di-O-(3,4,6-tri-O-Ac-2-PhthNbDGlc)-3,6--Di--O--Bn--aDMan]-4,6--O--Benzylidene--bDMan]]} -3, 6--Di--Obn2PhthNbDGlc} -2 PhthNbDGlc is a sugar that has been modified by methylation. It also contains saccharide and polysaccharides. This product is CAS No. 899891–14–8 and can be purchased through custom synthesis. The purity of this product is high and the modification is fluorination.

O-(D-glucopyranosylidene)amino N-phenylcarbamate is a synthetic monosaccharide that is used in our laboratory as an intermediate for the synthesis of complex carbohydrates. It is also used in the modification of polysaccharides and glycosylations. This compound has been shown to be stable to hydrolysis, methylation, and oxidation. O-(D-glucopyranosylidene)amino N-phenylcarbamate has been shown to be a high purity product with a CAS number of 104012-84-2.

Man-6 Glycan, 2-AB labelled is a custom synthesis of mannose-6-phosphate, a monosaccharide. The molecule contains six carbons and one phosphate group. It can be modified with fluorination, methylation, or click modification. This glycan is synthesized by the addition of an oligosaccharide to a polysaccharide. Mannose-6-phosphate is an Oligosaccharide that carries out glycosylation reactions in the body. It is used as a precursor for other glycans such as N-Acetylglucosamine and N-Acetylgalactosamine.

Dextran 2000 is a high molecular weight biocompatible polymer with transport properties. It is used in a variety of medical applications, such as red blood cell transfusions and the prevention of post-surgical adhesions. Dextran 2000 has been shown to be a safe and effective means of preventing hemolysis during red blood cell transfusion. This agent binds to amine groups on the surface of erythrocytes, which prevents complement activation and subsequent lysis. Additionally, dextran 2000 has been shown to exhibit low cytotoxicity against neuronal cells in vitro.

Allyl 6-O-benzyl 2-deoxy-3-O-(R)-1'-ethoxycarbonylethyl)-2-(2,2,2-trichloroethoxycarbonylamino)-a-D-glucopyranoside is a synthetic carbohydrate that can be custom synthesized. It is a saccharide, an oligosaccharide, and a sugar. This product has been fluorinated and methylated. The CAS number for Allyl 6-O-benzyl 2-deoxy-3-O-(R)-1'-ethoxycarbonylethyl)-2-(2,2,2-trichloroethoxycarbonylamino)-a-D-glucopyranoside is 589791.

Chromogenic substrate targeting beta-glucuronidase

Intermediate for synthesis of N-acetyllactosaminic glycans

4-Aminophenyl b-D-glucuronide sodium is a glycosylation reagent used in the synthesis of complex carbohydrates, polysaccharides and oligosaccharides.

2-Azido-2-deoxy-3,5-O-benzylidene-D-xylono-1,4-lactone is a synthetic sugar that is used in the synthesis of glycosylation, methylation and click modification reactions. It has been shown to be a potential precursor for polysaccharides and fluorinated saccharides. This product can be custom synthesized and is available at high purity.

Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. It also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods and may be used as an ingredient in culture media.

Laminaran is a polysaccharide that co-occurs with fucoidan and alginate in brown seaweeds such as Laminaria digitata, Laminaria cloustoni, Eisenia bicyclis and Thallus laminariae. It is a β-1,3-linked glucan which it is claimed stimulates the immune system in mammals and fish.
The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.

1-O-Methyl-beta-D-xylopyranoside is a matrix component that is used as an artificial sweetener. This product has been shown to have the ability to protect cells against radiation and toxic chemicals. 1-O-Methyl-beta-D-xylopyranoside also inhibits the growth of coliform bacteria by inhibiting their energy metabolism and may be used for wastewater treatment. It has been shown to be effective in analytical methods to identify the presence of human feces in water samples.

Fleetamine is a piperidine compound that has been shown to be an inhibitor of the enzyme glycosylation. Inhibitors of glycosylation are useful for treating diseases such as diabetes and Alzheimer's disease. It is thought that Fleetamine may inhibit human glycosylating enzymes, such as glucosyl transferase, which catalyzes the addition of a glucose molecule to a protein. This inhibition prevents the formation of oligosaccharides and glycoconjugates, which are necessary for proper functioning of cells.

2'-Azidoethyl a-mannopyranoside is a synthetic monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. This product has been custom synthesized for your specific needs. It is an off-white powder with purity greater than 99%. The methylation of this compound can be achieved by reacting it with sodium methoxide in methanol, followed by hydrolysis with sodium hydroxide. The azido group can also be converted to an acetyl group by reaction with acetic anhydride in pyridine.

Isosorbide dinitrate is a drug that belongs to the class of nitrates. It is used in the treatment of angina pectoris, as well as congestive heart failure and chronic heart failure. Isosorbide dinitrate has been shown to cause caspase-independent cell death in human leukemia cells and breast cancer cells. This may be due to its ability to inhibit mitochondrial membrane potential and interfere with intracellular calcium mobilization. The optimum concentration for isosorbide dinitrate is 10 µM, which inhibits the growth of bacteria, including Mycobacterium tuberculosis and Salmonella enterica serovar Typhimurium. The drug also inhibits the production of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α by inhibiting c-jun phosphorylation. Isosorbide dinitrate also has anti-inflammatory properties, which may be due to its ability to inhibit 4-hyd

Lactose is the principal sugar in human and most other mammalian milks, ( 4-O-(β-d-galactopyranosyl)-d-glucopyranose) (Collins, 2006). Lactose undergoes mutarotation; it is a reducing sugar and is significantly less soluble in water than sucrose. Lactose is much less sweet than sucrose (at ~1% about 0.15 (sucrose=1). The enzyme lactase (β-galactosidase), which is present in the small intestine, catalyzes hydrolysis of lactose to form glucose and galactose. Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. Lactose also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods (Linko, 1982).

11-Dehydroxygrevilloside B is a natural glycoside compound, which is primarily isolated from the plant genus Grevillea. This genus is known for its rich diversity of secondary metabolites with various biological activities. The mode of action of 11-Dehydroxygrevilloside B involves interactions with specific molecular targets, potentially influencing biochemical pathways associated with inflammation, oxidative stress, or other cellular processes. Its exact mechanism is still under research, aiming to unravel its potential therapeutic or protective effects. Applications of 11-Dehydroxygrevilloside B are mainly within the realm of biochemical and pharmacological research, where it serves as a subject for in vitro or in vivo experiments to explore its efficacy and safety profile. Its study contributes to understanding how plant-derived compounds can be harnessed for medicinal purposes and augments the exploration of novel drug candidates from natural sources.

1-deoxy-D-psicose is a deoxy sugar that can be used as a reagent for the conversion of 1-deoxy-d-fructose to d-psicose. It is useful in the synthesis of rhamnose, which is a precursor to pharmaceuticals and agrochemicals. 1-Deoxy-D-psicose can be used in the synthesis of l-rhamnose from d-psicose or vice versa. This process of converting one epimer to another isomerization is very efficient, with an 88% yield.