Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2637 produtos de "Nucleotídeos"
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Adenosine - Endotoxin level below 100 EU/g
CAS:Adenosine is a nucleoside that interacts with adenosine receptors in the central nervous system. It is found in most body tissues and fluids, including blood, cerebrospinal fluid, and synovial fluid. Adenosine has been shown to inhibit uptake of glucose and other substances in the brain. The uptake of adenosine by neurons is inhibited by solute transport inhibitors such as nevirapine, which prevents the accumulation of toxic levels of adenosine during excitotoxic injury. Adenosine also has thermodynamic properties that promote its removal from solution by binding to water molecules and forming crystals or precipitates. This property may be useful in the treatment of cerebral edema following traumatic brain injury.Fórmula:C10H13N5O4Pureza:Min. 99.0 Area-%Cor e Forma:White PowderPeso molecular:267.24 g/molAcetyl coenzyme A sodium salt
CAS:Acetyl-coenzyme A is an important intermediate in the metabolism of carbohydrates, fats, and proteins. It is a cytosolic molecule that is synthesized from Acetyl-CoA and ATP. The Michaelis–Menten kinetics describe the relationship between the concentration of acetyl-coenzyme A and the rate of its consumption. Acetyl co-enzyme A is found in many different tissues, including plants, animals, and humans. It has an important role in regulating cellular growth and differentiation by activating various enzymes involved in metabolic pathways. Acetyl CoA can be acetylated to form acetyl CoA carboxylic acid (ACC) which then turns into malonyl CoA through a series of reactions. Malonyl CoA then enters the Krebs cycle as a key intermediate for generating energy from fatty acids.Fórmula:C23H38N7O17P3S·xNaPureza:Min. 95%Cor e Forma:PowderPeso molecular:809.57 g/molN6-Benzoyl-2'-deoxy-2'-fluoroadenosine
CAS:N6-Benzoyl-2'-deoxy-2'-fluoroadenosine is an oligonucleotide that can be used to modulate the expression of survivin. It inhibits the expression of this protein by binding to its mRNA and preventing translation. N6-Benzoyl-2'-deoxy-2'-fluoroadenosine has shown potential for use in cancer treatment due to its ability to inhibit tumor growth and metastasis. It may also be used in the treatment of autoimmune diseases, such as rheumatoid arthritis, where it can inhibit the production of inflammatory cytokines.
Fórmula:C17H16FN5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:373.34 g/mol5-Acetoxymethyl-2'-deoxyuridine
CAS:5-Acetoxymethyl-2'-deoxyuridine (5-AOMUdR) is a nucleoside analog that inhibits the synthesis of DNA. It is phosphorylated to 5-acetoxymethyl uridine monophosphate, which inhibits DNA polymerase by competitive inhibition. This compound has been shown to induce apoptosis in vitro and inhibit HIV replication in cells. 5-AOMUdR has also been shown to be an effective anti-viral agent against influenza A virus.Fórmula:C12H16N2O7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:300.26 g/mol3'-O-Acetyl-2'-deoxyadenosine
CAS:Please enquire for more information about 3'-O-Acetyl-2'-deoxyadenosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:C12H15N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:293.29 g/molCytidine 2',3'-cyclic monophosphate monosodium
CAS:Cytidine 2',3'-cyclic monophosphate monosodium salt is a nucleotide that is used in the synthesis of DNA and RNA. It has antiviral and anticancer properties. Cytidine 2',3'-cyclic monophosphate monosodium salt is a high purity, high quality nucleotide with strong activator properties. It is also an excellent substrate for DNA polymerases, which may be due to its ability to bind to the phosphate groups on the enzyme's active site. This product can be used as a phosphoramidite during DNA synthesis or as an antiviral agent that inhibits viral replication by inhibiting the formation of viral DNA.Fórmula:C9H11N3O7P•NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:327.16 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine
CAS:N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine is a potent and selective inhibitor of the receptor tyrosine kinases Cck-A, which is overexpressed in certain tumour cells. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine blocks the activation of Cck-A by endothelin, thereby inhibiting the proliferation of tumour cells. This compound also has affinity for other protein kinases including receptor tyrosine kinase (RTK)s, which may be due to its tautomeric equilibrium.Fórmula:C32H33N3O7Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:571.62 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine is a versatile nucleoside building block.
Fórmula:C38H35N5O6Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:657.72 g/molAbacavir sulfate
CAS:Anti-viral; reverse transcriptase inhibitor
Fórmula:C14H18N6OH2SO4Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:670.75 g/molN4-Acetyl-5'-O-DMT-2'-O-methylcytidine
CAS:N4-Acetyl-5'-O-DMT-2'-O-methylcytidine is a cytidine analogue that has been synthesized to be used as an enzyme-linked probe. It is labelled with biotin and can be detected by binding to an antibody which has been labelled with a fluorescent tag. Cytidine analogues are synthesized on a solid phase and then cleaved from the support material. The spacer arm is added to the 5' end of the nucleotide and the 3'-OH group is modified with 2'-O-methyl groups. N4-Acetyl-5'-O-DMT-2'-O-methylcytidine has been shown to be sensitive in techniques such as solid phase synthesis, nucleic acid research, and immunoassays.Fórmula:C33H35N3O8Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:601.65 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose
CAS:Acadesine is a purine nucleoside analogue that inhibits the synthesis of ATP in cells. Acadesine blocks phosphorylation of adenosine monophosphate (AMP) to adenosine triphosphate (ATP) by inhibiting the activity of kinase-3, an enzyme involved in the production of ATP. Acadesine also inhibits the release of ATP from muscle cells into the blood stream and preferentially targets kidney cells, thereby reducing renal injury. Acadesine has been shown to be effective at reducing proteinuria and improving renal function in rats with acute kidney injury. Acadesine also has anti-inflammatory properties due to its ability to inhibit proteins that are involved in inflammation.Fórmula:C9H14N4O5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:258.23 g/mol2'-Deoxy-5-fluorouridine
CAS:2'-Deoxy-5-fluorouridine is a nucleoside analog that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It has been shown to inhibit the growth of cancer cells and induce apoptosis in vivo. 2'-Deoxy-5-fluorouridine has also been shown to inhibit tumor growth in animal models by inhibiting the production of reactive oxygen species and upregulating tumor suppressor genes, such as p53. This drug also has inhibitory effects on enzymes that are involved in cell proliferation, such as protein kinase C and tyrosine kinases. 2'-Deoxy-5-fluorouridine is metabolized by water vapor, so it must be administered with a humidifier or nebulizer. 2'-Deoxy-5-fluorouridine may cause side effects such as nausea, vomiting, and diarrhea.Fórmula:C9H11FN2O5Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:246.2 g/mol5-Methylcytidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:5-Methylcytidine-5'-triphosphate sodium salt is a nucleoside diphosphate that is used as an activator in the synthesis of DNA. It is also used as a building block in the synthesis of anticancer agents, such as 5-methylcytosine monophosphate and phosphoramidites. The chemical name for this product is 5-methylcytidine-5'-triphosphate sodium salt and its CAS number is 327174-86-7. This product is available for purchase at Sigma Aldrich with a purity of 99%.Fórmula:C10H18N3O14P3·xNaPureza:Min. 95%Cor e Forma:PowderPeso molecular:497.18 g/molAdenosine 5'-diphosphate monosodium salt
CAS:Used for energy storage and in nucleic acid metabolismFórmula:C10H14N5NaO10P2Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:449.18 g/molAbacavir
CAS:Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase (RT) inhibitor with anti-retroviral activity against HIV. Good oral bioavailability, high aqueous solubility and good cerebrospinal fluid penetrance. Synergistic with other nucleoside RT inhibitors such as AZT.Fórmula:C14H18N6OPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:286.33 g/mol2-Amino-2'-deoxyadenosine
CAS:2-Amino-2'-deoxyadenosine is a modified nucleoside, closely related to adenosine in which the 2'-hydroxyl group is replaced by an amino group. This compound has potential research applicationsFórmula:C10H14N6O3Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:266.26 g/molAdenylyl-3'-5'-cytidine
CAS:Adenylyl-3'-5'-cytidine (3'-5'-CYT) is a postulated naturally occurring dinucleoside that has been shown to be involved in many metabolic processes. It has been found to interact with serum albumin, which may be related to the molecule's ability to bind with the ligand and form a complex. 3'-5'CYT can be synthesized from cytidine using an enzyme called adenosine deaminase. This process is known as deamination. The product of this reaction can either be uracil or thymine, depending on the enzyme used. 3'-5'CYT is also a component of recombinant human polypeptides that have been shown to have anti-cancer properties.Fórmula:C19H25N8O11PPureza:Min. 95%Cor e Forma:PowderPeso molecular:572.42 g/molRibavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS:Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.Fórmula:C8H15N4O14P3·Na4Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:576.1 g/molp-Coumaryl-coenzyme A
CAS:Please enquire for more information about p-Coumaryl-coenzyme A including the price, delivery time and more detailed product information at the technical inquiry form on this page
Fórmula:C30H42N7O18P3SPureza:Min. 95%Cor e Forma:PowderPeso molecular:913.68 g/mol5'-Azido-5'-deoxyguanosine
CAS:5'-Azido-5'-deoxyguanosine is an analog of guanosine that can be synthesized in a solid-phase reaction. It can also be enzymatically generated from 5'-azido-5'-deoxyadenosine. This molecule is reactive and has been shown to be an effective inhibitor of DNA synthesis in vivo assays. The use of 5'-azido-5'-deoxyguanosine has been explored as a potential treatment for leishmaniasis, a disease caused by the protozoan parasite Leishmania donovani.Fórmula:C10H12N8O4Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:308.25 g/mol
