Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2637 produtos de "Nucleotídeos"
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2-Amino-9-(β-D-ribofuranosyl)purine
CAS:2-Amino-9-(β-D-ribofuranosyl)purine is a purine nucleoside consisting of the base 2-aminopurine linked via an N9-glycosidic bond to β-D-ribofuranose. As an analog of adenosine, it retains structural compatibility with nucleic acids but exhibits distinct biochemical properties, most notably intrinsic fluorescence. This makes it a valuable probe in molecular biology for studying nucleic acid structure, base pairing, and conformational changes, as its fluorescence is sensitive to local stacking interactions and environmental conditions.Fórmula:C10H13N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:267.24 g/mol5'-O-DMT-N2-DMF-guanosine
CAS:5'-O-DMT-N2-DMF-guanosine is a novel nucleoside that has been modified with an acetyl group on the 5'-hydroxyl group. This nucleoside has antiviral, anticancer and deoxyribonucleoside properties. It also activates diphosphate synthesis and inhibits protein synthesis. The drug is synthesized in high purity and quality, making it an excellent activator for phosphoramidites.Fórmula:C34H36N6O7Pureza:(%) Min. 85%Peso molecular:640.69 g/mol3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine
CAS:3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. This antiviral drug is a novel synthetic nucleoside analogue that is phosphorylated to form monophosphate, which inhibits the synthesis of RNA. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine has been shown to be effective against cancer cells by inhibiting ribonucleotide reductase and DNA synthesis. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine also inhibits DNA synthesis by blocking the enzymes DNA polymerase and deoxyribonucleoside kinase.Fórmula:C17H16N8O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:380.36 g/mol2-Amino-6-chloro-9-(b-D-ribofuranosyl)purine
CAS:Intermediate in the synthesis of nelarabineFórmula:C10H12ClN5O4Pureza:Min. 97 Area-%Cor e Forma:Off-White PowderPeso molecular:301.69 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine is a synthetic nucleoside that is used in the synthesis of RNA. It has been shown to be resistant to heat and both acidic and basic conditions. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine can be used for modifications of oligonucleotides and as a convenient sealant for the synthesis of DNA, RNA, or other nucleic acids. This product is neutralized with hydrochloric acid prior to use.Fórmula:C36H44N2O8SiPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:660.83 g/mol3-(3-Acetamido-3-carboxypropyl)uridine
CAS:acetylated derivative from 3-(3-amino-3-carboxypropyl)uridine
Fórmula:C15H21N3O9Pureza:Min. 95%Cor e Forma:SolidPeso molecular:387.34 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine
CAS:N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine is a novel nucleoside analog with antiviral, anticancer and immunomodulatory activities. It has been shown to inhibit the replication of HIV-1 and to induce apoptosis in tumor cells. N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine is a phosphoramidite that can be used for the synthesis of DNA, RNA, and deoxyribonucleotides. This product is synthesized by using an automated high purity process.Fórmula:C38H35N5O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:657.73 g/mol3'-O-Methylguanosine 5'-triphosphate lithium
CAS:3'-O-Methylguanosine 5'-triphosphate lithium is a nucleotide that has been synthesized and characterized. It is a biochemical regulatory molecule that is involved in the synthesis of DNA, RNA, and proteins. 3'-O-Methylguanosine 5'-triphosphate lithium binds to the guanine nucleotide binding protein G, which acts as an allosteric activator of the enzyme ribonucleotide reductase. The reconstituted enzyme system containing 3'-O-methylguanosine 5'-triphosphate lithium has demonstrated a high level of fidelity in the replication of dna templates.
Fórmula:C11H18N5O14P3•Li4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:564.97 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.Fórmula:C38H37N3O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:663.72 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine
CAS:4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine (4FA) is a potent inhibitor of the growth of HIV. It has been shown to inhibit the production of inflammatory cytokines and chemokines, which are associated with inflammatory diseases such as arthritis and asthma. 4FA has also been shown to inhibit glycogen synthase kinase 3 (GSK3), which is involved in the regulation of cellular signaling pathways that control cell growth and proliferation. Furthermore, 4FA inhibits an enzyme that is needed for viral replication and can be used as a therapeutic agent against viruses such as hepatitis C virus.Fórmula:C9H11FN6O4Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:286.22 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that can be used in the synthesis of oligomers. It is a synthetic nucleoside with an absorption maximum at 410 nm and emission maximum at 522 nm. This compound has been shown to be efficient in the synthesis of phosphoramidites and ligands, as well as in rna synthesis and modifications. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine may inhibit bacterial growth by binding to the ribosome, preventing protein synthesis.
Fórmula:C44H49N5O7SiPureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:787.97 g/mol8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt
CAS:Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.Fórmula:C10H10BrN5O6P·NaPureza:Min. 95%Cor e Forma:White PowderPeso molecular:430.08 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine
N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine is a nucleoside analog that inhibits the activity of HIV reverse transcriptase. It is an antiviral agent that prevents the synthesis of viral DNA by competitively inhibiting the incorporation of deoxynucleotide triphosphates into viral DNA. This drug also has been shown to be effective against cytomegalovirus (CMV), herpes simplex virus, and varicella zoster virus (VZV). N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine has been synthesized with phosphoramidites and purified to high quality standards. The chemical structure includes a modified sugar moiety, an altered base moiety, and a unique phosphate group.Fórmula:C41H41N5O8Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:731.79 g/mol1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol
CAS:1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol is a synthetic nucleoside analog for use in researchFórmula:C24H22N2O7Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:450.45 g/molS-Adenosyl-L-methionine disulfate tosylate
CAS:S-Adenosyl-L-methionine disulfate tosylate (SAMe) is a dietary supplement that is used to treat depression and liver disease. It is also a metabolite of the amino acid methionine, which is formed by the enzyme S-adenosylmethionine synthase. SAMe has been shown to inhibit the activation of caspase 3, which causes apoptosis in cells, and may be useful for treating cancer and other diseases. The chromatographic method used to separate SAMe from other compounds relies on its evaporative properties, due to its high water solubility.Fórmula:C22H34N6O16S4Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:766.8 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS:N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used in the synthesis of oligonucleotides. It is an activator of DNA and RNA synthesis, which has antiviral and antitumor properties. The CAS number for this compound is 81256-88-4.Fórmula:C44H49N5O7SiPureza:Min. 95%Cor e Forma:PowderPeso molecular:787.97 g/mol6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS:6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.Fórmula:C10H12N4O3SPureza:Min. 95%Cor e Forma:PowderPeso molecular:268.29 g/molN6-Benzoyl-2',3'-isopropylideneadenosine
CAS:N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.
Fórmula:C20H21N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:411.41 g/mol6-Benzylamino-9-(b-D-arabinofuranosyl)purine
CAS:6-Benzylamino-9-(b-D-arabinofuranosyl)purine is a nucleoside that is used as an activator and as an antiviral agent. It has been used in anticancer research, but it has not been found to have any significant effect against cancer cells. 6-Benzylamino-9-(b-D-arabinofuranosyl)purine is a modified ribonucleoside with a boronic acid group attached to the 9 position of the purine ring. This modification leads to increased stability of the nucleotide in alkaline conditions and improved cellular uptake. 6-Benzylamino-9-(b-D-arabinofuranosyl)purine can be phosphorylated on the 2',3' and 5' positions, forming 2',3'-diphosphate, 3'-diphosphate and 5'-triphosphate derivatives.Fórmula:C17H19N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:357.37 g/mol8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium
CAS:8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium salt (8-BrAMP) is an activated analog of adenosine that binds to the cyclase enzyme and inhibits its activity. It has been shown to inhibit the production of epidermal growth factor in a model system. 8-BrAMP also blocks the synthesis of cyclic nucleotides by inhibiting cyclic nucleotide phosphodiesterase, which results in increased levels of cAMP. 8-BrAMP has been shown to inhibit HIV infection by acting as a transcription-polymerase chain inhibitor and blocking HIV mRNA synthesis. The drug also inhibits cell lysis by binding to calmodulin and β-catenin.Fórmula:C10H11BrN5O5PS•NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:447.16 g/mol
