Nucleotídeos
Subcategorias de "Nucleotídeos"
Foram encontrados 2636 produtos de "Nucleotídeos"
S-Adenosyl-L-methionine
CAS:S-Adenosyl-L-methionine (SAM-e) is a co-substrate involved in methyl group transfer to nucleic acids, proteins and lipids. SAM-e is produced in the liver from adenosine triphosphate (ATP) and methionine by action of the enzyme methionine adenosyltransferase. Therapeutic use of S-adenosyl-L-methionine includes osteoarthritis, liver disease and major depressive disorder. S-Adenosyl-L-methionine is available as a dietary supplement.Fórmula:C15H22N6O5SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:398.44 g/molStearoyl coenzyme A free acid hydrate
CAS:Stearoyl coenzyme A free acid hydrate is a natural, non-synthetic lipid molecule that belongs to the group of fatty acids. It is found in the form of a white crystalline powder and has a melting point at approximately 56°C. Stearoyl CoA free acid hydrate is an essential component of cellular metabolism, carrying out reactions such as desaturase, dextran sulfate, and other enzyme activities. Stearoyl CoA free acid hydrate may have therapeutic applications for metabolic disorders and obesity. The enzyme complex that catalyzes the synthesis of stearoyl CoA free acid hydrate in adipocytes is ATP-binding cassette transporter (ABC) A1 and ABCG1, which are members of the superfamily of ATP-binding cassette (ABC) transporters. It also plays a role in regulating immune responses via Toll-like receptor 4 (TLR4).Fórmula:C39H70N7O17P3S•H2OPureza:Min. 92 Area-%Cor e Forma:White PowderPeso molecular:1,052.01 g/mol2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine
CAS:2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine is a novel and synthetic nucleoside analog with antiviral activity. It inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This compound has been shown to be an activator of PPARs in vitro.Fórmula:C21H38N2O6Si2Pureza:Min. 95%Peso molecular:470.72 g/mol5-Bromo-2'-deoxycytidine
CAS:5-Bromo-2'-deoxycytidine is a synthetic nucleoside analogue that is used to treat diabetic neuropathy. It is structurally similar to cytidine, and inhibits the enzyme DNA polymerase by intramolecular catalysis. This causes deamination of the 5-bromo group, which prevents further synthesis of DNA. 5-Bromo-2'-deoxycytidine has been shown to be effective in vivo in a mouse model for inflammatory bowel diseases, including colitis and eosinophilic enteritis. The drug was also found to inhibit the production of Eosinophil peroxidase from HL-60 cells in vitro.Fórmula:C9H12BrN3O4Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:306.11 g/mol5′-O-DMT-LNA N-Bz 5-Me cytidine
CAS:5′-O-DMT-LNA N-Bz 5-Me cytidine is a protected LNA cytidine nucleoside.Fórmula:C39H37N3O8Pureza:Min. 95%Peso molecular:675.73 g/molThymidine-3',5'-diphosphate disodium salt
CAS:Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.Fórmula:C10H14N2Na2O11P2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:446.15 g/molAdenylyl-3'-5'-guanosine sodium salt
CAS:3'-Adenylyl-5'-guanosine ammonium salt is a dinucleoside that competes with guanosine for binding to the enzyme adenylate cyclase. This reaction leads to increased levels of cyclic AMP, which causes an increase in the rate of viral replication. 3'-Adenylyl-5'-guanosine ammonium salt has been shown to inhibit the growth of pyogenic bacteria such as Streptococcus pyogenes and has also been used to treat influenza infections. 3'-Adenylyl-5'-guanosine ammonium salt is an inorganic compound that is found in tobacco. It can be synthesized from uridine and p-nitrophenyl phosphate by the reaction: 3'--O--(CH2)4--COOH + H2N--PO4--> 3'--O--(CH2)4--CONH2 + H3PO4
Fórmula:C20H24N10O11P·NaPureza:Min. 95%Peso molecular:634.43 g/mol2'-Deoxy-N2-methylguanosine
CAS:2'-Deoxy-N2-methylguanosine is a nucleoside with anticancer properties. It is a phosphoramidite, which is an analog of the natural nucleotide guanosine, where the 2'-hydroxyl group has been replaced by a methylene group. This compound is used in DNA synthesis and RNA synthesis. It can be used as a monophosphate or diphosphate. It also has antiviral and anti-inflammatory activities, as well as N2-methylamino moiety that can be used for the treatment of cancer and inflammatory diseases such as arthritis.
Fórmula:C11H15N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:281.27 g/mol8-Aza-7-deaza-2'-deoxyguanosine
CAS:8-Aza-7-deaza-2'-deoxyguanosine is an alkynylated, cross-linked, single stranded nucleic acid. It has been shown to be effective at cross-linking and cross-linking nucleic acids. 8-Aza-7-deaza-2'-deoxyguanosine binds to the 7 deazapurine residues in DNA, forming a covalent bond between the two strands of the helix. This binding prevents the strand from unwinding and prevents the replication of DNA. The thermodynamic data for this compound shows that it is stable in both hot and cold water, which makes it a good candidate for use in research as well as in clinical settings.Fórmula:C10H13N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:267.24 g/molKinetin riboside-5'-monophosphate sodium salt
CAS:Kinetin riboside-5'-monophosphate sodium salt is a synthetic nucleotide that has been modified to include a phosphate group at the 5' position. Kinetin riboside-5'-monophosphate sodium salt is an activator of DNA synthesis and can be used for the treatment of viral infections. It also shows anticancer activity and is effective against cancer cells that are resistant to other cancer drugs.Fórmula:C15H16N5Na2O8P·H2OPureza:Min. 95%Cor e Forma:PowderPeso molecular:489.29 g/molUridine-3',5'-cyclic monophosphate sodium salt
CAS:Uridine-3',5'-cyclic monophosphate sodium salt is a phosphotriester that is an intermediate in the biosynthesis of nucleosides. It is also a phosphodiesterase inhibitor, which means it inhibits the breakdown of cyclic nucleotides and allows them to accumulate. This drug has been shown to increase platelet production and has anti-inflammatory effects. Uridine-3',5'-cyclic monophosphate sodium salt is a human metabolite that can be synthesized from uridine, which is present in DNA, RNA, and food sources such as meat, eggs, and milk. The synthesis of uridine-3',5'-cyclic monophosphate sodium salt requires phosphoramidite as a precursor.
Fórmula:C9H10N2O8P·NaPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:328.2 g/mol3-Acetylpyridine adenine dinucleotide disodium, reduced form
CAS:Reduced synthetic analog of NADH with an acetylpyridine modification. It is used as a reducing substrate to study the mechanisms of NAD(P)+-dependent reductases and to probe the active sites and catalytic processes of these important enzymes through its altered spectroscopic and binding properties. The disodium salt ensures good solubility for biochemical applications.Fórmula:C22H30N6O14P2•Na2Pureza:Min. 95%Cor e Forma:Slightly Yellow PowderPeso molecular:710.43 g/mol8-Nitroguanosine
CAS:8-Nitroguanosine is a nucleotide analogue that inhibits the activity of cyclic GMP in cells. It has been found to inhibit the growth of bacteria and cancer cells, as well as to stimulate the production of reactive oxygen species in brain cells. 8-Nitroguanosine has also been shown to inhibit the activity of cyclase enzymes in liver cells, which may be useful for treating liver disease. 8-Nitroguanosine is used as a chemical base for monoclonal antibodies that are used to study brain functions and pathogenic mechanisms.Fórmula:C10H12N6O7Pureza:Min. 95%Peso molecular:328.24 g/molLamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution
Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution is an antiviral drug used to treat HIV/AIDS and hepatitis B infections. It is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication, acting by blocking the viral enzyme reverse transcriptase. Lamivudine-5'-triphosphate tetratriethylammonium salt - ca.15 mM Aqueous solution also inhibits cellular viral DNA synthesis and has been shown to exhibit anticancer activity in vitro and in vivo. This product is synthesized from raw materials through a novel process that involves modification of the phosphoramidite monophosphate with tetratriethylammonium salts.Fórmula:C32H74N7O12P3SPureza:Min. 95%Peso molecular:873.96 g/mol7-Deaza-2'-C-ethynyladenosine
CAS:7-Deaza-2'-C-ethynyladenosine (7DAA) is a research inhibitor that is classified as a polymerase inhibitor. It binds to the active site of the viral NS5B polymerase and inhibits RNA synthesis, which leads to virus replication. 7DAA has shown activity against hepatitis B virus (HBV) and hepatitis C virus (HCV). It also shows multifunctional properties in its inhibition of HBV genotypes A1, A3, and D1. In addition, 7DAA interacts with the RNA binding site on HCV polymerase protein and prevents binding of the viral RNA genome to this site. 7DAA also inhibits HIV replication by preventing assembly of the reverse transcriptase enzyme complex at an early stage.Fórmula:C13H14N4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:290.27 g/mol2-O-Ethylthymidine
CAS:2-O-Ethylthymidine is a nucleoside that is used to study the structure and dynamics of DNA. It can be synthesized by reacting 1-β-D-arabinofuranosylbenzene with ethylmercury acetate. 2-O-Ethylthymidine can be used in kinetic studies as it is specific for dna. It has been shown to have a conformational change, which is stabilized by the presence of an aromatic ring such as phenanthrene. This compound was also found to inhibit neuroblastoma cell growth in vitro.
Fórmula:C12H18N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:270.28 g/mol7-Deaza-2',3'-dideoxy-7-iodoadenosine
CAS:7-Deaza-2',3'-dideoxy-7-iodoadenosine is a nucleoside analogue that is used as an antiviral, anticancer, and antifungal agent. It is a modified form of adenosine which inhibits viral replication by inhibiting the activity of reverse transcriptase. 7-Deaza-2',3'-dideoxy-7-iodoadenosine has also been shown to inhibit DNA synthesis in cells by blocking the incorporation of dCTP into DNA. This nucleoside analogue has shown potential for use as an activator in phosphoramidite chemistry and as a deoxyribonucleoside in oligonucleotide synthesis.Fórmula:C11H13IN4O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:360.15 g/molCiticoline sodium
CAS:Citicoline is a complex organic molecule, a form of B-vitamin choline that acts as an intermediate in many biosynthetic pathways, for example, in the biosynthesis of cell membrane phospholipids. As a dietary supplement, citicoline is a source of choline and cytidine, two components that are quickly absorbed in the intestine and across the blood-brain barrier. The neuroprotective properties of citicoline improves mental performance increasing the levels of other brain-related chemicals like dopamine and norepinephrine, helping with recovery in stroke patients, reducing memory loss due to aging and improving vision in patients with glaucoma.Fórmula:C14H26N4O11P2•NaPureza:Min. 98.0 Area-%Cor e Forma:White To Off-White SolidPeso molecular:511.31 g/mol3'-O-Methylinosine
CAS:3'-O-Methylinosine is a synthetic nucleoside that inhibits the synthesis of viral DNA and RNA by interacting with the enzyme ribonucleotide reductase. This antiviral agent has been shown to be effective against a wide range of viruses, including human cytomegalovirus, herpes simplex virus type 1, varicella-zoster virus, and influenza A virus. 3'-O-Methylinosine has also been shown to inhibit the growth of cancer cells in vitro and in vivo.
Fórmula:C11H14N4O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:282.25 g/mol3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin
CAS:3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin is a nucleoside analog that is used as an activator of phosphoramidite. It can be used as a building block in the synthesis of modified phosphoramidites and it has antiviral, anticancer, and antiinflammatory properties. 3-Methyl-8-(2-deoxy-b-D-ribofuranosyl)isoxanthopterin is a novel nucleoside analog that can be used to synthesize DNA or RNA. It is also an inhibitor of deoxyribonucleoside kinase, preventing the conversion of deoxyribonucleosides into diphosphate monophosphates.
Fórmula:C12H15N5O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:309.28 g/mol
