Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2636 produtos de "Nucleotídeos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
6-Methyluridine
CAS:Methyluridine is a derivative of uridine that is used in the synthesis of pyrimidine nucleotides. This drug is also an inhibitor of orotidine 5′-monophosphate decarboxylase, which converts orotic acid to uracil. The conformational properties of methyluridine have been studied and found to be similar to those of other purine derivatives, such as adenine and guanine. In addition, methyluridine has been shown to inhibit the growth of typhimurium and increase the production of uracil in human lymphocytes. Methyluridine is metabolized by hydroxylation in liver microsomes, yielding 6-carboxylic acid.Fórmula:C10H14N2O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:258.23 g/molXanthosine-5'-triphosphate triethylammonium salt - 100 mM aqueous solution
CAS:Inhibitor of adenylyl and guanylyl cyclaseFórmula:C10H15N4O15P3·xC6H15NPureza:Min. 95%Cor e Forma:Colorless PowderPeso molecular:524.17 g/molGuanosine 5'-diphosphate sodium
CAS:Pyruvate kinase substrate
Fórmula:C10H15N5O11P2•Na2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:466.19 g/molGuanosine5'-diphosphate
CAS:Pyruvate kinase substrateFórmula:C10H15N5O11P2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:443.2 g/molFludarabine phosphate
CAS:Fludarabine phosphate is an antileukemic drug that inhibits DNA polymerase α and β, as well as other enzymes in the nucleotide synthesis pathway. It is used to treat patients with chronic myelogenous leukemia (CML) who have developed resistance to other treatments. Fludarabine phosphate has been shown to induce a cytotoxic effect against tumor cells by binding to ATP-binding cassette transporter proteins on the cell membrane and inhibiting intracellular targets such as DNA, RNA, and protein synthesis. Fludarabine phosphate has also been shown to inhibit the growth of tumor cells through synergistic interactions with other anticancer drugs such as hydroxyurea or busulfan, which may be due to its ability to inhibit enzyme activities such as erythrocyte alkaline phosphatase.
Fórmula:C10H13FN5O7PPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:365.21 g/mol3'-Deoxyadenosine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:3'-Deoxyadenosine-5'-triphosphate sodium salt is a nucleotide that has been shown to be effective in chemotherapy. It is a substrate for the synthesis of DNA, RNA, and ATP. 3'-Deoxyadenosine-5'-triphosphate sodium salt is also a building block for DNA polymerase, which is an enzyme that synthesizes DNA from a template. It has been shown to have anticancer activity in drug-resistant cells and can be used as an alternative to purine analogs such as 6-mercaptopurine or cladribine. 3'-Deoxyadenosine-5'-triphosphate sodium salt has been shown to inhibit the production of nucleotides by blocking their conversion into triphosphates, which are necessary for DNA replication and repair. This inhibition leads to apoptosis in cells with high levels of nucleotide turnover such as cardiac and myeloid cells. The drug interactions may depend on theFórmula:C10H16N5O12P3Pureza:Min. 95%Cor e Forma:Colorless PowderPeso molecular:491.18 g/molALS-8176
CAS:ALS-8176 is a benzimidazole compound that has been shown to be effective against both wild-type and syncytial viruses. It is also active against the hepatitis B virus, which causes fulminant hepatitis in humans and death in 30% of cases. The antiviral activity of ALS-8176 was demonstrated by its ability to inhibit viral DNA synthesis and to prevent the release of new viral particles. ALS-8176 has also been shown to have a broad spectrum of activity against paramyxoviruses, including mumps, measles, and respiratory syncytial virus (RSV). This drug can be used for the treatment of influenza A and B when administered during the early stages of infection. ALS-8176 blocks the antibody response to influenza virus infection as well as monoclonal antibody binding sites on the hemagglutinin protein, preventing fusion between infected cells.Fórmula:C18H25ClFN3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:433.86 g/molThymidine-3',5'-diphosphate disodium salt
CAS:Thymidine-3',5'-diphosphate disodium salt is an antiviral and anticancer drug. It is a modified nucleoside which is synthesized from thymidine-3',5'-diphosphate and sodium bicarbonate (NaHCO3). This drug inhibits the synthesis of DNA and RNA, thereby inhibiting viral replication. Thymidine-3',5'-diphosphate disodium salt also has an antitumor effect by preventing the production of DNA in tumor cells.Fórmula:C10H14N2Na2O11P2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:446.15 g/mol3'-Phosphoadenosine-5'-phosphosulfate lithium salt hydrate
CAS:Universal sulfonate donor for in vivo sulfonation by sulfotransferasesFórmula:C10H15N5O13P2S·xLi·yH2OPureza:Min. 60 Area-%Cor e Forma:White PowderPeso molecular:507.27 g/mol2'-Deoxyadenosine
CAS:2'-Deoxyadenosine is a nucleoside that is found in DNA. It has been shown to have potent anticancer activity against carcinoma cell lines and to bind to the adenosine receptor A3. 2'-Deoxyadenosine has also been shown to inhibit the production of inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6, from nuclear extracts of mouse tumor cells. This nucleoside may be a potential drug target for the treatment of cancer and inflammation.Fórmula:C10H13N5O3Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:251.24 g/molThymidine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:Thymidine-5'-triphosphate sodium salt is a modified nucleoside with anticancer properties. It is a high-quality, high-purity ribonucleoside that can be used as an activator for the synthesis of deoxyribonucleosides and phosphoramidites. Thymidine-5'-triphosphate sodium salt has antiviral activity, which is due to its ability to inhibit viral DNA replication and transcription. This compound also has the potential to be used in the treatment of cancer cells by inhibiting DNA synthesis and cell division.Fórmula:C10H17N2O14P3·xNaPureza:Min. 95%Cor e Forma:PowderPeso molecular:482.17 g/mol2'-O-Propargyladenosine
CAS:2'-O-Propargyladenosine is a modified nucleoside that belongs to the group of deoxyribonucleosides. It is an activator of viral DNA polymerases, which causes the synthesis of viral DNA to stop. This compound has antiviral and anticancer activities. 2'-O-Propargyladenosine has been shown to be effective against various human cancer cell lines in vitro and in vivo. It is a synthetic nucleoside with high purity, showing no detectable impurities by HPLC analysis.
Fórmula:C13H15N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:305.29 g/mol2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine
CAS:2'-Deoxy-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)uridine is a novel and synthetic nucleoside analog with antiviral activity. It inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This compound has been shown to be an activator of PPARs in vitro.Fórmula:C21H38N2O6Si2Pureza:Min. 95%Peso molecular:470.72 g/mol2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine
CAS:2',3'-Dideoxy-2',3'-didehydro-2'-fluorocytidine (ddC) is a nucleoside with antiviral activity. The mechanism of action is not well understood, but ddC has been shown to inhibit the proliferation of human immunodeficiency virus (HIV). It is also active against isolates of herpes simplex virus and vesicular stomatitis virus. The elimination half-life of ddC in humans is about 8 hours. In humans, this drug is eliminated by methylation and glucuronidation reactions. The pharmacokinetics of ddC have been studied in animals, including rats and rabbits, with preliminary indications that the elimination half-life may be longer than in humans.Fórmula:C9H10FN3O3Pureza:Min. 95%Peso molecular:227.19 g/mol2'-Amino-2'-deoxycytidine
CAS:2'-Amino-2'-deoxycytidine is a modified nucleoside, based on cytidine. In this compound 2'-hydroxyl group has been replaced by an amino group, which can change hydrogen bonding patterns potentially affecting how it interacts with biomolecules.Fórmula:C9H14N4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:242.24 g/molN6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:N6-Benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an analog of adenosine triphosphate (ATP). It is used in the study of protein kinase C. ATP and its analogs are able to phosphorylate proteins and regulate their activity. This study has shown that N6-benzyladenosine 5'-triphosphate sodium salt - 10 mM aqueous solution is an atp analog that activates protein kinase C, leading to the phosphorylation of proteins. This analog also inhibits tyrosine kinases, which may be due to its ability to inhibit the reuptake of serotonin and other transmitters.Fórmula:C17H22N5O13P3·xNaPureza:Min. 95%Cor e Forma:Colorless PowderPeso molecular:597.3 g/molUridine-3',5'-cyclic monophosphate sodium salt
CAS:Uridine-3',5'-cyclic monophosphate sodium salt is a phosphotriester that is an intermediate in the biosynthesis of nucleosides. It is also a phosphodiesterase inhibitor, which means it inhibits the breakdown of cyclic nucleotides and allows them to accumulate. This drug has been shown to increase platelet production and has anti-inflammatory effects. Uridine-3',5'-cyclic monophosphate sodium salt is a human metabolite that can be synthesized from uridine, which is present in DNA, RNA, and food sources such as meat, eggs, and milk. The synthesis of uridine-3',5'-cyclic monophosphate sodium salt requires phosphoramidite as a precursor.
Fórmula:C9H10N2O8P·NaPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:328.2 g/molStearoyl coenzyme A free acid hydrate
CAS:Stearoyl coenzyme A free acid hydrate is a natural, non-synthetic lipid molecule that belongs to the group of fatty acids. It is found in the form of a white crystalline powder and has a melting point at approximately 56°C. Stearoyl CoA free acid hydrate is an essential component of cellular metabolism, carrying out reactions such as desaturase, dextran sulfate, and other enzyme activities. Stearoyl CoA free acid hydrate may have therapeutic applications for metabolic disorders and obesity. The enzyme complex that catalyzes the synthesis of stearoyl CoA free acid hydrate in adipocytes is ATP-binding cassette transporter (ABC) A1 and ABCG1, which are members of the superfamily of ATP-binding cassette (ABC) transporters. It also plays a role in regulating immune responses via Toll-like receptor 4 (TLR4).Fórmula:C39H70N7O17P3S•H2OPureza:Min. 92 Area-%Cor e Forma:White PowderPeso molecular:1,052.01 g/molAdenosine 2',3'-cyclic monophosphate
CAS:Adenosine 2',3'-cyclic monophosphate triethylammonium salt (AMP-TEA) is a structural analogue of adenosine. It is a potent inhibitor of protein synthesis by preventing the phosphodiesterase activity of cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase. AMP-TEA can be used as a tool to study translation in tissue culture, as well as to examine the effects on protein synthesis and other biochemical reactions that are regulated by cyclic nucleotides. It is also used for the preparation of tissue samples for enzymatic analysis or for radiolabeling experiments. AMP-TEA has an optimum pH of 4.5, but can be used at lower or higher pH values. The optimal temperature range for use is between 0°C and 50°C, with the maximum stability occurring at 37°C.Fórmula:C10H12N5O6PPureza:Min. 95%Cor e Forma:PowderPeso molecular:329.21 g/molAdenylyl-3'-5'-guanosine sodium salt
CAS:3'-Adenylyl-5'-guanosine ammonium salt is a dinucleoside that competes with guanosine for binding to the enzyme adenylate cyclase. This reaction leads to increased levels of cyclic AMP, which causes an increase in the rate of viral replication. 3'-Adenylyl-5'-guanosine ammonium salt has been shown to inhibit the growth of pyogenic bacteria such as Streptococcus pyogenes and has also been used to treat influenza infections. 3'-Adenylyl-5'-guanosine ammonium salt is an inorganic compound that is found in tobacco. It can be synthesized from uridine and p-nitrophenyl phosphate by the reaction: 3'--O--(CH2)4--COOH + H2N--PO4--> 3'--O--(CH2)4--CONH2 + H3PO4
Fórmula:C20H24N10O11P·NaPureza:Min. 95%Peso molecular:634.43 g/mol
