Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2638 produtos de "Nucleotídeos"
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N4-Benzoyl-5'-O-DMT-5-methylcytidine
CAS:N4-Benzoyl-5'-O-DMT-5-methylcytidine is a deoxyribonucleoside that has been modified to make it resistant to nucleases. N4-Benzoyl-5'-O-DMT-5-methylcytidine is an antiviral agent, which inhibits the synthesis of viral DNA by inhibiting the activity of viral DNA polymerase. It also acts as an activator for cellular DNA polymerases and phosphoramidites. The drug can be used in the treatment of HIV and other retroviruses, herpes viruses, and certain types of cancer.Fórmula:C38H37N3O8Pureza:Min. 95%Cor e Forma:White SolidPeso molecular:663.73 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine
CAS:N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine (BTS) is a novel phosphoramidate monophosphate nucleoside analog that has been modified to be resistant to the ribonuclease A enzyme. BTS is an activator of DNA synthesis and inactivator of RNA synthesis, which makes it useful for the treatment of cancer and antiviral infections. This drug is synthesized using high quality reagents and can be used for the production of phosphoramidites to produce high purity oligonucleotides.Fórmula:C23H31N5O5SiPureza:Min. 95%Cor e Forma:PowderPeso molecular:485.61 g/mol7-Deaza-2'-deoxy-7-iodoguanosine
CAS:7-Deaza-2'-deoxy-7-iodoguanosine is a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm. 7-Deaza-2'-deoxy-7-iodoguanosine can be synthesized using the following general equation:
Fórmula:C11H13IN4O4Pureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:392.16 g/molCytidine 5'-diphosphate disodium salt
CAS:Cytidine 5'-diphosphate disodium salt (CDP) is a monophosphate nucleotide that is an antiviral agent and an anticancer drug. CDP inhibits viral replication by inhibiting the synthesis of DNA, RNA, and proteins. It has been shown to be effective against herpes virus, vaccinia virus, Newcastle disease virus, and influenza A virus. CDP also has anti-cancer effects as it inhibits the growth of various tumor cells in vivo and in vitro. This drug is a phosphoramidite nucleoside that can be used for the modification of other nucleosides or as an activator for DNA synthesis.Fórmula:C9H13N3O11P2·Na2Pureza:Min. 90.0 Area-%Cor e Forma:White PowderPeso molecular:447.14 g/molN2-Isobutyryl-2'-O-methylguanosine
CAS:N2-Isobutyryl-2'-O-methylguanosine (IBOG) is a modified nucleoside that can be used as an activator for DNA synthesis. IBOG is a high purity, high quality chemical with CAS No. 63264-29-9 and has antiviral and anticancer properties.Fórmula:C15H21N5O6Pureza:Min. 95%Cor e Forma:White To Yellow SolidPeso molecular:367.36 g/mol2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt
CAS:2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt is a prodrug that is converted to fluorouracil in the body. Fluorouracil inhibits the activity of thymidylate synthase and other enzymes involved in DNA synthesis, which are associated with cancer. It is also an inhibitor binding to the enzyme RNA polymerase II, which may contribute to its anti-cancer effects. 2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt has been shown to inhibit the growth of human tumor cells in culture and in animal models. The matrix effect may be responsible for this activity. 2'-Deoxy-5-fluorouridine 5'-monophosphate sodium salt can be used as a model system for studying cancer tissues.Fórmula:C9H12FN2O8P·xNaPureza:Min. 85 Area-%Cor e Forma:White Off-White PowderPeso molecular:326.17 g/molThymidine
CAS:Thymidine, also known as deoxythymidine (dT), is a pyrimidine deoxynucleoside that pairs with deoxyadenosine (dA) in a double stranded DNA. It’s used as a biochemical modulator of antimetabolites such as 5-fluorouracil (5-FU), 1-beta-D-arabinofuranosylcytosine (Cytarabine) and methotrexate (MTX) in cancer therapy. It’s also the enantiomer of telbivudine, an antiviral drug used to treat hepatitis B virus (HBV) infection.
Fórmula:C10H14N2O5Pureza:Min. 99.0 Area-%Cor e Forma:White PowderPeso molecular:242.23 g/mol5'-O-DMT-2'-O-methylguanosine
CAS:5'-O-DMT-2'-O-methylguanosine is a novel nucleoside analog that has been modified to contain the 2' methyl group at the 5' position. This modification enhances its anticancer activity and cellular uptake by cells. The 5'-O-DMT-2'-O-methylguanosine monophosphate synthesized in this study is chemically stable, high purity, and high quality.Fórmula:C32H33N5O7Pureza:Min. 95%Peso molecular:599.65 g/molb-Nicotinamide adenine dinucleotide phosphate
CAS:Coenzyme and regenerating electron donor in catabolic processesFórmula:C21H28N7O17P3Pureza:Min. 80 Area-%Cor e Forma:Off-White PowderPeso molecular:743.41 g/molPolyinosinic acid-polycytidylic acid, homopolymer (1:1)
CAS:Polyinosinic acid-polycytidylic acid (Poly I:C), an agonist of TLR3 toll-like receptors, is a synthetic double-stranded RNA analog, consisting of polyinosinic acid (poly I) paired with polycytidylic acid (poly C), forming a stable duplex structure.PolyI:C stimulates the secretion of pro-inflammatory cytokines and type I interferon through its interaction with endosomal Toll-like receptor 3 (TLR-3) and the cytoplasmic receptors melanoma differentiation-associated gene 5 (MDA-5) and retinoic acid-inducible gene I (RIG-I). This immunostimulant activity makes Poly I:C a useful vaccine adjuvant and is used in vaccine formulations. Poly I:C and its stabilized analogs (e.g., poly-ICLC) are also being actively researched for their dual role in oncology: directly targeting tumors and acting as immune potentiators. For example Poly I:C can induce apoptosis in tumor cells and stimulate immunogenic cell death and is therefore being explored alongside chemotherapy, radiotherapy, and checkpoint inhibitors, helping to overcome resistance mechanisms and strengthen treatment outcomes.We can supply PolyI:C to all stages of your project - from R&D and preclinical phases right up to GMP commercial manufacture. Contact our team for custom Poly I:C products. For more on poly I:C read out blog 'Poly I:C: A Vaccine Adjuvant With Oncological Potential.'Fórmula:(C10H13N4O8P)x•(C9H14N3O8P)xCor e Forma:Powder2-Thiouridine-5'-monophosphate triethylammonium salt - aqueous solution
CAS:2-Thiouridine-5'-monophosphate triethylammonium salt is a synthetic nucleotide analog that inhibits the growth of cells by binding to the anticodon region, which blocks the entrance of amino acids into the ribosome. It also inhibits cell growth by preventing glycosidic bond formation and inhibiting purine metabolism. This drug has functional groups that allow it to be purified by chromatography and diffraction techniques. The drug is not active against bacteria that are resistant to glutamic acid, such as Mycobacterium tuberculosis or Mycobacterium avium complex. 2-Thiouridine-5'-monophosphate triethylammonium salt is a precursor for other drugs, such as cytidine 5'-triphosphate, which can be used in chemotherapy treatments.Fórmula:C21H43N4O8PSPureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:542.63 g/mol2'-C-Methylcytidine
CAS:Broad-spectrum anti-viral; inhibitor of HCV NS5B RNA polymeraseFórmula:C10H15N3O5Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:257.25 g/molPseudouridine
CAS:Pseudouridine is a nucleoside that is produced by the deamination of uridine. It has been shown to have biological properties in vitro, and may be involved in the pathogenesis of infectious diseases. Pseudouridine has been shown to act as an allosteric ligand for toll-like receptor 4. It also has a thermodynamic stability that is higher than that of uridine, which may allow it to serve as a more stable substrate for enzymes such as ribonucleotide reductase and dTMP synthetase.Fórmula:C9H12N2O6Pureza:Min. 99.0 Area-%Peso molecular:244.20 g/molRef: 3D-W-201269
-Unit-ggA consultar1gA consultar5gA consultar250mgA consultar500mgA consultar2500mgA consultar5'-(4-Fluorosulfonylbenzoyl)adenosine HCI
CAS:ATP analog; covalent inhibitor of anthrax edema factorFórmula:C17H17ClFN5O7SPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:489.86 g/mol5'-O-DMT-2'-O-methyl-5-methyluridine
CAS:5'-O-DMT-2'-O-methyl-5-methyluridine is a modified nucleoside that is used in the synthesis of DNA. It is an anticancer drug and antiviral agent. 5'-O-DMT-2'-O-methyl-5-methyluridine has been shown to inhibit the growth of leukemia cells, even when they are resistant to other drugs. It also inhibits certain viruses, such as herpes simplex virus type 1 (HSV1), by preventing viral replication and inhibiting protein synthesis. This nucleoside is synthesized from 5'-O-DMT and 2'-O-methylcytosine.Fórmula:C32H34N2O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:574.64 g/mol2'-Deoxyisocytidine
CAS:2'-deoxyisocytidine is a nucleoside that is used in biochemical research. It can be synthesized by two methods: solid-phase synthesis and depyrimidination. 2'-deoxyisocytidine has been shown to be more efficient than other fluorescent nucleosides when used with the excimer laser technique. The stability of this compound has also been shown to be greater than other fluorescein-based compounds, which makes it an appropriate substitute when using phosphoramidite chemistry.Fórmula:C9H13N3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:227.22 g/molAdenosine 5'-triphosphate disodium salt hydrate
CAS:Adenosine 5'-triphosphate disodium salt hydrate (ATP 2Na) is a nucleoside triphosphate acting as the essential part of energy storage and metabolism in vivo. It plays a crucial role in many biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function, often described as the "molecular unit of currency" for intracellular energy transfer.
Fórmula:C10H14N5Na2O13P3·xH2OPureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:551.14 g/mol5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside
CAS:5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside is a chemical compound that has been shown to be neurotoxic in vitro. It has significant cytotoxicity against human leukemia cells (HL60) and induces neuronal death. This drug also inhibits the production of neurotrophic factors, which are vital for the normal development of neurons. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside inhibits transcriptional regulation of genes that encode for receptors and enzymes. The compound is chemically stable and does not degrade easily by hydrolysis or oxidation. It can bind to polymerase chain reaction (PCR) primers and inhibit DNA synthesis. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside also affects cell nuclei by inhibiting DNA synthesis and enzyme activities.Fórmula:C12H12Cl2N2O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:319.15 g/mol5'-O-Methylthymidine
CAS:5'-O-methylthymidine is an antiviral, monophosphate nucleoside that is structurally similar to thymidine and cytidine. 5'-O-methylthymidine has been shown to inhibit the growth of cancer cells in vitro. The mechanism by which 5'-O-methylthymidine inhibits the growth of cancer cells is not known but may be due to its ability to act as a diphosphate activator or a deoxyribonucleoside phosphoramidite.Fórmula:C11H16N2O5Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:256.26 g/mol2'-Deoxy-5-methylcytidine
CAS:2'-Deoxy-5-methylcytidine is a nucleoside analogue that inhibits the synthesis of DNA. It prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine has been shown to inhibit colon cancer cells in vitro, and may be a potential biomarker for bowel disease. This drug is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules.
Fórmula:C10H15N3O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:241.25 g/mol
