Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2637 produtos de "Nucleotídeos"
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2'-Deoxy-5-methylcytidine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:2'-Deoxy-5-methylcytidine-5'-triphosphate sodium salt - 10 mM aqueous solution is an inhibitor of the methyl transferase domain that is found in all DNA methyltransferases. It has been shown to inhibit transcriptional regulation and cellular transformation, as well as to induce DNA damage. The optimum pH for this compound is 7.4 and it hydrolyzes at pH levels lower than 5.0.Fórmula:C10H18N3O13P3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:481.18 g/mol2'-C-Methylguanosine 5'-monophosphate triethyl ammonium salt - Aqueous solution
2'-C-Methylguanosine 5'-monophosphate triethyl ammonium salt - Aqueous solution is a synthetic nucleotide analog for use in researchFórmula:C11H16N5O8P·C12H32N2Pureza:Min. 95%Cor e Forma:Clear liquid.Peso molecular:581.64 g/mol4-Amino-5-chloro-2,6-dimethylpyrimidine
CAS:4-Amino-5-chloro-2,6-dimethylpyrimidine is a supramolecular complex that is characterized by the coordination geometry of its metal ion and the donor atoms. It has been proposed as a potential drug for the treatment of bacterial infections, such as tuberculosis. The 4-Amino-5-chloro-2,6,dimethylpyrimidine is structurally similar to nucleobases and may be able to form hydrogen bonds with water molecules. This molecule also has a high melting point and is not soluble in water. It can be protonated at different pH values and forms complexes with hydroxyl groups found in nucleic acids.Fórmula:C6H8ClN3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:157.6 g/mol2,4-Diamino-6,7-dimethylpteridine
CAS:2,4-Diamino-6,7-dimethylpteridine is a ligand that can bind to an orphan cytosine opposite an abasic site in RNA duplexes
Fórmula:C8H10N6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:190.21 g/mol6-Chloro-9-(b-D-ribofuranosyl)purine
CAS:6-Chloro-9-(b-D-ribofuranosyl)purine is a purine analog that inhibits the synthesis of DNA, RNA, and protein. It has been shown to have physiological effects in cells, and it has been used as a positive control for enzyme activity studies. 6-Chloro-9-(b-D-ribofuranosyl)purine binds to an enzyme called hydroxymethylbilane synthase (HMBS), which inhibits the production of a molecule called tetrahydrobiopterin (THB). THB is essential for the synthesis of nitric oxide (NO), an important neurotransmitter that regulates neuronal death. 6-Chloro-9-(b-D-ribofuranosyl)purine also has significant cytotoxicity against melanoma cells in vitro.Fórmula:C10H11ClN4O4Pureza:Min. 96 Area-%Cor e Forma:PowderPeso molecular:286.68 g/molThymidine-5'-diphosphate-4-keto-6-deoxy-D-glucose disodium salt
CAS:Thymidine-5'-diphosphate-4-keto-6-deoxy-D-glucose disodium salt is a precursor in the synthesis of nucleoside sugars in pathways such as rhamnose biosynthesis.Fórmula:C16H22N2O15P2Na2Pureza:Min. 85 Area-%Cor e Forma:White PowderPeso molecular:590.28 g/molN6-Cyclopentyl-2'-C-methyl-adenosine
CAS:N6-Cyclopentyl-2'-C-methyl-adenosine is an antiviral agent that inhibits the synthesis of DNA by preventing the formation of RNA from DNA. It has been shown to be effective against HIV and other retroviruses. N6-Cyclopentyl-2'-C-methyl-adenosine is a synthetic nucleoside that is activated by phosphorylation in cells, which leads to the synthesis of monophosphate (5'-AMP). This compound is used for the treatment of cancer and HIV infection.Fórmula:C16H23N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:349.39 g/mol2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine
CAS:2,6-Diamino-9-[3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-β-D-ribofuranosyl]purine is a protected nucleoside derivative that can potentially be used as an intermediate in the chemical synthesis of nucleoside analogs, especially for RNA or DNA oligonucleotides. This compounds has a 2,6-Diaminopurine – a purine analog structurally similar to adenine but with an additional amino group at the 2-position and a β-D-ribofuranosyl. The 3′ and 5′ hydroxyl groups of the ribose are protected with a bulky 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS) group. This is a silyl protecting group often used to block reactivity during nucleoside synthesis.Fórmula:C22H40N6O5Si2Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:524.77 g/mol2'-Deoxy-2'-fluoroguanosine
CAS:2'-Deoxy-2'-fluoroguanosine is a modified nucleoside analog where the base is guanine, the sugar is deoxyribose, and a fluoro group is attached to the 2' position of the sugar ring. This modification potnetially enhances the stability and nuclease resistance of the nucleoside, making it a useful tool in molecular biology and drug development.
Fórmula:C10H12FN5O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:285.23 g/molDeoxyribonucleic acid low molecular weight from salmon sperm
CAS:This low molecular DNA (deoxyribonucleic acid) from salmon sperm is a fragment that is an effective indicator of the presence of guanine in urine samples, and can be used to detect lipoperoxidation in animal hemocytes. It has also been shown to be a sublethal oxidative stress agent for human urine, which induces irreversible oxidation in the enzyme activities of signal detection. According to some recent research studies, this product is being investigated as an environmental pollutant indicator and could be used as an effective wastewater treatment method.Cor e Forma:Powder3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)adenosine
CAS:Used as a protected adenosine nucleoside in RNA synthesis. The 1,1,3,3-tetraisopropyl-1,3-disiloxanediyl (TIPDS or TBDPSi2) group is a bulky, acid-labile protecting group specifically designed to protect the 3' and 5' hydroxyl groups of ribonucleosides during RNA oligonucleotide synthesis.Fórmula:C22H39N5O5Si2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:509.76 g/mol2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution
CAS:2'-C-Methylcytidine 5'-triphosphate triethylammonium salt - aqueous solution, is a synthetic nucleotide analog. It has potential application in antiviral research, particularly for studying RNA-dependent RNA polymerase (RdRP) activity in RNA viruses. It mimics the natural cytidine triphosphate (CTP) but includes a 2'-C-methyl modification on the ribose sugar.Fórmula:C10H18N3O14P3·4C6H15NPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:901.94 g/mol2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine
CAS:2'-Deoxy-5'-O-DMT-N6-isobutyryladenosine is a modified ribonucleoside that has antiviral and anticancer activity. It is synthesized by modifying the 5' hydroxyl group of the natural nucleoside, 2'-deoxyadenosine, with a 6-aminohexanoic acid to give 2'-deoxy-5'-O-(2,4,6-trimethoxybenzoyl)adenosine. This modification increases the affinity for viral DNA polymerases, leading to higher antiviral activity. The drug also has antitumor effects against human leukemia cells in culture.Fórmula:C35H37N5O6Pureza:Min. 95%Cor e Forma:Off-White To Light (Or Pale) Yellow SolidPeso molecular:623.72 g/mol5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine
CAS:5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, synthetic nucleoside with antiviral and antitumor activity. It is an analogue of 5'-O-DMT-2'-O-(2-methoxyethyl)uridine, which has been shown to be active against herpes simplex virus type 1 (HSV1) in vitro. The phosphoramidites of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine are modified at the 2' position with a methyl group and at the 5' position with a methoxyethyl group. These modifications make it more resistant to degradation by intracellular enzymes. The anticancer activity of 5'-O-DMT-2'-O-(2-methoxyethyl)-5-methyluridine was demonstrated in preclinical studies using human tumor cell lines.Fórmula:C34H38N2O9Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:618.67 g/mol9-(2',3',5'-Tri-O-benzyl-β-D-arabinofuranosyl)adenine
CAS:9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is a nucleoside that has shown anticancer and antiviral properties. It inhibits replication of DNA and RNA in cells, which may be due to its ability to inhibit the synthesis of deoxyribonucleotides and ribonucleotides. This compound is synthetically produced from 2',3',5'-tri-O-benzyl b-D-arabinofuranosyl chloride and adenine monophosphate (AMP). 9-(2',3',5'-Tri-O-benzyl-b-D-arabinofuranosyl)adenine is also known as arabinoside A.Fórmula:C31H31N5O4Pureza:Min. 95%Peso molecular:537.61 g/mol5'-Deoxythymidine
CAS:5'-Deoxythymidine is a nucleoside analog with low-energy electrons. This drug inhibits the synthesis of DNA by binding to the ribonucleotide reductase enzyme and preventing the conversion of ribonucleotides to deoxyribonucleotides. 5'-Deoxythymidine has been shown to inhibit cell growth in tumor cell lines, which may be due to its ability to interfere with mirna-mediated gene expression. This drug also has a kinetic effect on regulatory proteins, such as cyclin-dependent kinases, that are involved in the regulation of cell cycle progression.
Fórmula:C10H14N2O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:226.23 g/molβ-Nicotinamide adenine dinucleotide
CAS:Nicotinamide adenine dinucleotide (NAD), is a very important and essential coenzyme formed by the union of two nucleotides covalently bond to each other by their phosphates group. NAD is present in cells either in its oxidative form or in its reduced form, NAD+ and NADH respectively. They take part in many redox reactions, carrying electrons from one molecule to another.Fórmula:C21H27N7O14P2Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:663.43 g/molUridine 5'-triphosphate dihydrate trisodium salt
CAS:Uridine 5'-triphosphate dihydrate trisodium salt is a nucleotide that is involved in the synthesis of RNA. This product has been used as a supplement to promote healthy eyes and skin, as well as to treat Alzheimer's disease. It has been shown to be an efficient method for the detection of active substances by hydrophilic interaction chromatography (HILIC). The HILIC method involves separating molecules based on their hydrophobic or hydrophilic properties, which are determined by the ionic strength of the solution. Uridine 5'-triphosphate dihydrate trisodium salt binds with chloride ions, which prevents it from binding with other organic compounds. The chloride ions then serve as an end point that can be detected using ultraviolet light.Fórmula:C9H12N2O15P3·3Na·2H2OPureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:586.12 g/molN6,3'-O-Dibenzoyl-2'-deoxyadenosine
CAS:N6,3'-O-Dibenzoyl-2'-deoxyadenosine is a nucleoside that is used as a biochemical reagent in molecular biology. N6,3'-O-Dibenzoyl-2'-deoxyadenosine has been shown to be an inhibitor of the enzyme phosphodiesterase and also binds to DNA. This compound has been shown to have antibacterial activity against Gram-positive bacteria, such as Staphylococcus aureus and Clostridium perfringens. The lipophilicity of this compound allows it to cross the cell membrane and cleave DNA at the site of replication. N6,3'-O-Dibenzoyl-2'-deoxyadenosine is an analog of 6,4’-dihydroxybenzophenone (DBP) and can be synthesized from DBP by reacting with dibenzoyl chloride in chloroform
Fórmula:C24H21N5O5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:459.47 g/molN4-Benzoyl-2'-deoxycytidine
CAS:N4-Benzoyl-2'-deoxycytidine is a fluorescent nucleoside that has been used to study the molecular interactions between sugar residues and the phosphate groups of nucleic acids. It is used as a reagent for glycosidation, which involves the formation of a glycosidic linkage between an alcohol group in a saccharide or oligosaccharide and the hydroxyl group in an aromatic acid. N4-Benzoyl-2'-deoxycytidine has also been synthesized by solid-phase techniques. This synthetic method is based on phosphoramidite chemistry and uses an automated DNA synthesizer to produce oligonucleotides with specific sequences. The synthesis of this nucleoside relies on the use of fluorescent dyes such as fluorescein, rhodamine, and coumarin to monitor progress during synthesis.Fórmula:C16H17N3O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:331.33 g/mol
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