Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3573 produtos de "Nucleosídeos"
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N3-Methylthymidine
CAS:N3-Methylthymidine is a metalloprotease inhibitor that has been shown to inhibit the activity of epidermal growth factor (EGF). N3-Methylthymidine is also an effective inhibitor of HIV infection. The inhibitory effect on HIV infection is due to the competitive inhibition of viral protease and subsequent degradation of viral proteins. N3-Methylthymidine inhibits the synthesis and release of infectious herpes simplex virus particles. This drug also inhibits the growth of human tumor cells in culture by inhibiting cell proliferation, most likely due to its ability to inhibit EGF. An analytical method for determining the concentration of this drug in plasma using chemical ligation has been developed.Fórmula:C11H16N2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:256.26 g/molCytidine 5'-triphosphate disodium dihydrate
CAS:Cytidine 5'-triphosphate (CTP) disodium dihydrate prevents the action of aspartate carbamoyltransferase, an enzyme involved in pyrimidine biosynthesis. CTP serves as a molecule of high energy and acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.Fórmula:C9H16N3O14P3•(H2O)2•Na2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:565.17 g/molCytarabine
CAS:Fórmula:C9H13N3O5Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:243.22dNTP bundle, 4 x 100mM aqueous solution
CAS:Each dNTP supplied in a separate vialPureza:Min. 99 Area-%Cor e Forma:Clear Liquid2,4-Diamino-6-hydroxypyridine sulphate
CAS:2,4-Diamino-6-hydroxypyridine sulphate is a nucleoside for use in research applicationsFórmula:C4H6N4O•(H2SO4)xPureza:Min. 95%Cor e Forma:PowderPeso molecular:224.2 g/mol2'-Deoxy-2'-fluorocytidine-5'-triphosphate tetralithium
CAS:2'-Deoxy-2'-fluorocytidine-5'-triphosphate tetralithium is a modified nucleoside analog where the base is cytosine, the sugar is deoxyribose with a fluoro modification at the 2' position, and the molecule is phosphorylated at the 5' position with a triphosphate group.Fórmula:C9H11FLi4N3O13P3Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:508.88 g/molN2-Acetyl-5'-O-DMT-2'-O-methyl guanosine
CAS:2'-O-Me protected nucleosideFórmula:C34H35N5O8Peso molecular:641.67 g/mol4-(b-D-Ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one
CAS:Ribonucleosides, Deoxyribonucleosides and Activator are a group of synthetic compounds that are used in the synthesis of DNA. Ribonucleosides and Deoxyribonucleosides are nucleotides that contain ribose or deoxyribose as the sugar moiety. Activator is an activator for DNA polymerase, which catalyses the formation of a phosphodiester bond between two adjacent 3'-5' phosphate groups on a single strand of DNA. Ribonuclesides, Deoxyribonucleosides and Activator are used in recombinant DNA technology to synthesize DNA molecules containing modified bases. The CAS number for Ribonuclesides, Deoxyribonucleosides and Activator is 59892-40-9.
Fórmula:C10H12N4O5Pureza:Min. 95%Peso molecular:268.23 g/molQueuosine
CAS:Queuosine is a modified nucleoside found in the tRNA of both eukaryotic and prokaryotic organisms. It is primarily sourced from the gut microbiota and obtained through dietary intake, as humans lack the biosynthetic machinery to produce it endogenously. Queuosine plays a crucial role in cellular processes by contributing to the accuracy of protein synthesis, impacting cellular growth and maintenance. Its importance extends to understanding the molecular mechanisms underpinning various physiological processes and the potential for dysregulation in diseases. Ongoing research is exploring queuosine's implications in cellular metabolism, including its role in cancer biology and neurobiology. Understanding the pathways and effects of queuosine incorporation into tRNA may provide insights into novel therapeutic avenues for targeting metabolic disorders and diseases associated with translational fidelity.Fórmula:C17H23N5O7Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:409.39 g/mol5-Fluorouridine-5'-triphosphate sodium salt
CAS:5-Fluorouridine-5'-triphosphate sodium salt is an analog of uridine that has been used in the treatment of metastatic colorectal cancer. It is a prodrug that is metabolized to 5-fluorouracil, its active form. 5-Fluorouridine-5'-triphosphate sodium salt inhibits the synthesis of thymidylate, one of the precursors to DNA, and blocks the production of nucleotides. This results in cell lysis and death by apoptosis. The drug also inhibits epidermal growth factor receptor (EGFR), which may contribute to its antitumor effects.Fórmula:C9H14N2O15P3FPureza:Min. 95%Peso molecular:502.13 g/moldNTP pre-mixes, 10 mM aqueous solution
CAS:dATP, dTTP, dCTP and dGTP pre-mixed in a single vialFórmula:C10H16N5O12P3Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:491.18 g/mol9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)guanine
CAS:9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine is a nucleoside phosphorylase inhibitor that is used to treat inflammatory bowel disease. It has been shown to be effective in treating women with inflammatory bowel disease, and has no significant side effects. 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine inhibits the bacterial enzyme nucleoside phosphorylase, which is responsible for the conversion of guanosine triphosphate (GTP) to guanosine diphosphate (GDP). This inhibition prevents the synthesis of DNA and RNA by blocking the conversion of GTP and GDP into AMP and GMP. The drug binds to the active site of nucleoside phosphorylase, which is located in the bacterial cytoplasmic membrane. 9-(2'-Deoxy-2'-fluoroFórmula:C10H12FN5O4Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:285.24 g/mol2',3'-Di-O-benzoyluridine
CAS:2',3'-Di-O-benzoyluridine is a nucleoside for use in research applications
Fórmula:C23H20N2O8Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:452.41 g/mol2'-Deoxyadenosine 5'-O-thiophosphate sodium salt
CAS:2'-Deoxyadenosine 5'-O-thiophosphate sodium salt is a synthetic nucleotide that has antiviral, anticancer and antitumor properties. It is a modified deoxyribonucleoside and it activates the synthesis of DNA by acting as an activator. This drug is not found in nature and it has shown to inhibit the growth of human breast cancer cells in cell culture.Fórmula:C10H14N5O5PSPureza:Min. 95%Peso molecular:347.29 g/molCytidine 5'-diphosphocholine
CAS:Cytidine 5'-diphosphocholine is a nucleotide that is a precursor of uridine 5'-triphosphate and cytidine 5'-monophosphate, which are important for DNA synthesis. Cytidine 5'-diphosphocholine is used in the preparation of samples for experiments. This compound has been shown to induce neuronal death in an experimental model. It has also been shown to inhibit polymerase chain reactions and affect the activity of enzymes such as alpha-7 nicotinic acetylcholine receptors and glutamate decarboxylase. Cytidine 5'-diphosphocholine has been found to have no effect on basic fibroblast cells, but it does have physiological effects on human erythrocytes.Fórmula:C14H26N4O11P2Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:488.32 g/molGuanosine 5'-monophosphate disodium salt
CAS:Guanosine 5'-monophosphate disodium salt (GMPDS) is an antiviral agent that inhibits the synthesis of viral nucleic acids by competitive inhibition of the enzyme ribonucleotide reductase. GMPDS has been shown to inhibit the replication of a number of RNA viruses, including influenza A and B, herpes simplex virus type 1, and human immunodeficiency virus type 1. This drug also has been shown to decrease cyclic adenosine monophosphate (cAMP) levels in cells by inhibiting phosphodiesterase activity. GMPDS is used for treatment of infectious diseases such as influenza A, herpes, and HIV-1.Fórmula:C10H12N5Na2O8PPureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:407.18 g/mol9-(b-D-Arabinofuranosyl)hypoxanthine
CAS:9-(b-D-Arabinofuranosyl)hypoxanthine is a glycosylated analogue of the incretin hormone glucagon-like peptide-1 (GLP-1). It has been shown to inhibit Streptococcus pyogenes and other bacteria. 9-(b-D-Arabinofuranosyl)hypoxanthine has also been shown to have inhibitory properties against zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant. This drug has not been studied in clinical trials for antiviral prophylaxis or arabinoside. The only known side effects are drug interactions with cyclin D2 and nitrate reductase.
Fórmula:C10H12N4O5Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:268.23 g/mol1-(β-D-Arabinofuranosyl)thymine
CAS:1-(β-D-Arabinofuranosyl)thymine is a nucleoside analog. It has a similar structure to thymidine. It has possible applications in research into the specificity and kinetics of thymidine kinases and has demonstrated antiviral activity against some viruses.Fórmula:C10H14N2O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:258.23 g/mol2'-Deoxy-2'-fluoroguanosine-5'-triphosphate tetralithium
CAS:2'-Deoxy-2'-fluoroguanosine-5'-triphosphate tetralithium salt is a chemically modified nucleotide used in molecular biology and pharmaceutical research. It is a guanosine analog featuring both a 2'-fluoro substitution on the sugar and a 5'-triphosphate group, with tetralithium as the counterion to improve solubility and stability.Fórmula:C10H15FN5O13P3·xLiPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:525.17 g/mol3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
CAS:3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It has shown to be effective against a variety of viruses including HIV-1, herpes simplex virus type 1, influenza A virus, vaccinia virus, and vesicular stomatitis virus. 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt also inhibits the growth of cancer cells in vitro. This drug is a modified nucleoside with a phosphoramidite backbone and a 3'-azido group at one end. The other end contains a beta D glucuronic acid moiety. The modifications allow for the inhibition of DNA synthesis by blocking the incorporation of deoxyribonucleotides into DNA chains.
Fórmula:C16H20N5NaO10Pureza:Min. 95%Cor e Forma:PowderPeso molecular:465.35 g/mol
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