Sistema complementar
O sistema complemento é uma parte crucial da resposta imunológica, consistindo em uma série de pequenas proteínas que melhoram a capacidade dos anticorpos e das células fagocíticas de eliminar patógenos de um organismo. Essas proteínas trabalham juntas para opsonizar patógenos, induzir respostas inflamatórias e lisar diretamente as membranas dos patógenos, desempenhando um papel vital na imunidade inata e na função imunológica geral. Na CymitQuimica, fornecemos proteínas de alta qualidade do sistema complemento para apoiar seus estudos imunológicos e pesquisas clínicas.
Foram encontrados 166 produtos de "Sistema complementar"
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Tesidolumab
CAS:Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.Pureza:99.72% (SEC-HPLC) - > 95%Cor e Forma:LiquidPeso molecular:142 kDa (average)PMX 205 acetate(514814-49-4 free base)
PMX 205 acetate is an antagonist of complement C5a receptor (C5aR; CD88).Fórmula:C47H66N10O8Pureza:99.4%Cor e Forma:SolidPeso molecular:899.09Ref: TM-T12506L1
1mg105,00€5mg266,00€10mg350,00€25mg745,00€50mg1.189,00€100mg1.735,00€1mL*10mM (DMSO)374,00€Cyclosporin A
CAS:Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.Fórmula:C62H111N11O12Pureza:99.00% - 99.92%Cor e Forma:White PowderPeso molecular:1202.61Ravulizumab
CAS:Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.80 kDaDexamethasone
CAS:Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.Fórmula:C22H29FO5Pureza:98% - 99.91%Cor e Forma:Crystals From Ether (Ntp 1992)Peso molecular:392.46SB290157 trifluoroacetate
CAS:SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).Fórmula:C24H29F3N4O6Pureza:98.93% - 99.89%Cor e Forma:SolidPeso molecular:526.513-O-(2'E,4'Z-Decadienoyl)ingenol
3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.Fórmula:C30H42O6Cor e Forma:SolidPeso molecular:498.66Compstatin TFA
Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).Fórmula:C68H100F3N23O19S2Cor e Forma:SolidPeso molecular:1664.79Pegcetacoplan acetate
Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.Cor e Forma:Odour SolidATWLPPR Peptide TFA
ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.Fórmula:C42H62F3N11O11Pureza:98%Cor e Forma:SolidPeso molecular:954JPE-1375
CAS:JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.Fórmula:C49H63FN10O9Cor e Forma:SolidPeso molecular:955.08PMX-53
CAS:PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.Fórmula:C47H65N11O7Pureza:98%Cor e Forma:SolidPeso molecular:896.09L-156,602
CAS:L-156,602 has a wide range of applications in life science related research.Fórmula:C38H64N8O13Cor e Forma:SolidPeso molecular:840.973Claseprubart
CAS:Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.Cor e Forma:LiquidVemircopan
CAS:Vemircopan is a complement factor D inhibitor.Fórmula:C29H28BrN7O3Cor e Forma:SolidPeso molecular:602.493TLQP-21
CAS:TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.Fórmula:C107H170N40O26Pureza:98%Cor e Forma:SolidPeso molecular:2432.75PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Fórmula:C71H123N19O21S2·xC2HF3O2Cor e Forma:SolidAMY-101
CAS:AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.Fórmula:C83H117N23O18S2Pureza:98%Cor e Forma:SolidPeso molecular:1789.11ARC186
ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.Cor e Forma:SolidPeso molecular:120702.76PMX 205
CAS:PMX 205 is an effective complement antagonist of the C5a receptor.Fórmula:C45H62N10O6Pureza:98%Cor e Forma:SolidPeso molecular:839.04
