Antibióticos Naturais e Semissintéticos
Os antibióticos naturais e semissintéticos são caracterizados por estruturas químicas com anéis heterocíclicos e grupos funcionais ativos que inibem o crescimento de microrganismos. Suas estruturas permitem-lhes interagir com os processos vitais das bactérias, tornando-os úteis para o tratamento de infecções bacterianas. Os antibióticos semissintéticos podem ser modificados para melhorar o espectro de atividade ou a resistência à degradação.
Na CymitQuimica, oferecemos antibióticos naturais e semissintéticos de alta qualidade para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 6348 produtos de "Antibióticos Naturais e Semissintéticos"
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Posaconazole Impurity 92
CAS:Fórmula:C14H15F2N3O2Cor e Forma:White To Off-White SolidPeso molecular:295.29Ivermectin B1a (>85%)
CAS:Produto Controlado<p>Applications Ivermectin B1a is a major component of Ivermectin (I940800), a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);; Caly, L., et al.: Antivir. Res., 178<br></p>Fórmula:C48H74O14Pureza:>85%Cor e Forma:NeatPeso molecular:875.093,3'-Trithiobis-D-valine
CAS:Produto ControladoFórmula:C10H20N2O4S3Cor e Forma:NeatPeso molecular:328.47Tylosin-d3 (100 Mug/mL in Methanol)
CAS:Fórmula:C46H74D3NO17Cor e Forma:ColourlessPeso molecular:916.10(6R-trans)-7-[[(2-Amino-4-thiazolyl)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
CAS:Produto ControladoFórmula:C14H14N4O4S2Cor e Forma:BeigePeso molecular:366.423-Ethyl-2,5-pyrazinediethanol
CAS:Produto Controlado<p>Impurity Clavulanate Potassium EP Impurity C<br>Applications 3-Ethyl-2,5-pyrazinediethanol (Clavulanate Potassium EP Impurity C) is an impurity of Clavulanic acid (C563750). High concentrations of Clavulanic acid but not of its degradation products decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus.<br>References Zupke, C., et al.: Biotechnol. Prog., 10, 489 (1994), Finlay, J., et al.: J .Antimicrob. Chemother., 52, 18 (2003), Alper, H., et al.: Science, 314, 1565 (2006), Brethauer, S., et al.: Biotechnol. Bioeng., 98, 356 (2007),<br></p>Fórmula:C10H16N2O2Cor e Forma:YellowPeso molecular:196.25Gatifloxacin-d4
CAS:Produto Controlado<p>Applications An antibacterial.<br>References Bauernfeind, A.: J. Antimicro. Chemother., 40, 639 (1997), Fukuda, H., et al.: Antimicrob. Ag. Chemother., 42, 1917 (1998),<br></p>Fórmula:C192H4H18FN3O4Cor e Forma:NeatPeso molecular:379.426-Hydroxy-6-defluoro Ciprofloxacin Hydrochloride (~90%)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 6-Hydroxy-6-defluoro Ciprofloxacin Hydrochloride (Ciprofloxacin EP Impurity F) is a the salt form of 6-Hydroxy-6-defluoro Ciprofloxacin (H825210), hydroxy analog of Ciprofloxacin (C482500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ge, L., et al.: Environ. Sci. Technol., 44, 2400 (2010),<br></p>Fórmula:C17H19N3O4•HClPureza:~90%Cor e Forma:Light Beige SolidPeso molecular:329.353646Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether
CAS:Produto ControladoFórmula:C25H42O4SiCor e Forma:NeatPeso molecular:434.684'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin
CAS:Produto Controlado<p>Applications 4'-O-2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl Selamectin is an impurity of Selamectin (S247990) which is a topical parasiticide. Selamectin (S247990) is also used as a veterinary antihelminithic agent on animals.<br>References Eshar, D., et al.: J. Am. Veterin. Med. Association., 241, 1056 (2012); Geis-Asteggiante, L., et al.: J. Chromatograph., 1258, 43 (2012);<br></p>Fórmula:C50H75NO14Cor e Forma:NeatPeso molecular:914.133’-N-Didesmethyl-3’-N-tosyl Azithromycin
CAS:Produto Controlado<p>Applications 3’-N-Didesmethyl-3’-N-tosyl Azithromycin is a derivative of Azithromycin (A927000, dihydrate) which is a semi-synthetic macrolide antibiotic.<br>References Langtry, H.D., et al.: Drugs, 56, 273 (1998)<br></p>Fórmula:C44H75N3O15SCor e Forma:Off-White To Light YellowPeso molecular:918.1425-Desacetyl Rifampicin-d3 (>85%)
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A labelled metabolite of Rifampicin.<br>References Blumenfeld,O.O., et al.: J. Biol. Chem., 236, 2472 (1961), Cowxan, R.A., et al.: Biochem. Biophys. Res. Commun, 23, 799 (1966)<br></p>Fórmula:C41H53D3N4O11Cor e Forma:NeatPeso molecular:783.92Temsirolimus (~90%)
CAS:Produto Controlado<p>Applications Ester analog of Rapamycin.<br>References Raymond, E., et al.: J. Clin. Oncol., 22, 2336 (2004), Galanis, E., et al.: J. Clin. Oncol., 23, 5294 (2005)<br></p>Fórmula:C56H87NO16Pureza:>80%Cor e Forma:NeatPeso molecular:1030.29(2S,3S)-3-Amino-2-[[(2Z)-2-(2-amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]butanoic Acid Trifluoroacetic Acid Salt
CAS:Produto Controlado<p>Applications (2S,3S)-3-Amino-2-[[(2Z)-2-(2-amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]butanoic Acid is an impurity of Aztreonam (A965200), the first totally synthetic monocyclic β-lactam antibiotic.<br>References Murugan, R., Narayanan, S.S.: Anal. Chem. Indian J., 8, 36 (2009); Sykes, R.B., et al.: Antimicrob. Agents Chemother., 21, 85 (1982); Florey, K., et al.: Anal. Profiles Drug Subs., 17, 1 (1988)<br></p>Fórmula:C13H19N5O6S•x(C2HF3O2)Cor e Forma:NeatPeso molecular:373.3811402Flomoxef Sodium
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Flomoxef Sodium is a sodium salt derivative of Flomoxef (F401850); an oxacephem derived beta-lactam antibiotic that is particularly effective against gram-positive bacteria.<br>References Miwa, H. et al.: Chemotherapy, 35, 121 (1987); Mikamo, H. et al.: Curr. Therap. Res., 56, 873 (1995);<br></p>Fórmula:C15H17F2N6NaO7S2Cor e Forma:NeatPeso molecular:518.45Amoxicillin-d4 (Major)
CAS:Produto Controlado<p>Applications Labelled semi-synthetic antibiotic related to Penicillin. Antibacterial.<br>References Brogden, R.N., et al.: Drugs, 18, 169 (1979), Bird, A.E., et al.: Anal. Profiles Drug Subs. Excip., 23, 1 (1994),<br></p>Fórmula:C16D4H15N3O5SCor e Forma:NeatPeso molecular:369.4288Enrofloxacin
CAS:<p>Impurity Enrofloxacin USP Related Compound Mixture<br>Applications Fluorinated quinolone antibacterial. Enrofloxacin USP Related Compound Mixture.<br>References Altreuther, P., et al.: Vet. Med. Rev., 2, 87 (1987),<br></p>Fórmula:C19H22FN3O3Cor e Forma:YellowPeso molecular:359.39Amphotericin B Methyl Ester 90%
CAS:Produto Controlado<p>Applications Amphotericin B Methyl Ester is the methyl ester derivative of the polyene antibiotic Amphotericin B (A634250). Amphotericin B Methyl Esterin is a cholesterol binding compound that showed inhibiton of human immunodeficiency virus type 1 (HIV-1).<br>References Waheed, A.A. et al.: J. Biol. Chem., 281, 28699 (2006); Waheed, A. et al.: J. Virol., 82, 9776 (2008); Waheed, A., et al.: J. Biol. Chem., 281, 28699 (2006)<br></p>Fórmula:C49H77NO16Pureza:>80%Cor e Forma:Dark Yellow To Dark OrangePeso molecular:936.133-(4-Hydroxyphenyl)-2(1H)-pyrazinone
CAS:Produto ControladoFórmula:C10H8N2O2Cor e Forma:NeatPeso molecular:188.18Pneumocandin B0
CAS:Produto Controlado<p>Applications Pneumocandin B0 is the major analogue of a family of lipopeptides isolated from several species of several different genera, such as Cryptosporiopsis, Glarea and Pezicula. Pneumocandin B0 is a potent antifungal and acts by inhibition of the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.<br>References Schwartz, R., et al.: J. Antibiot., 45, 1853 (1992); Petersen, L., et al.: Appl. Microbiol. Biotechnol., 62, 263 (2003), Petersen, L., et al.: Appl. Microbiol. Biotechnol., 62, 263 (2003),<br></p>Fórmula:C50H80N8O17Cor e Forma:NeatPeso molecular:1065.21Chloramphenicol Succinate Sodium
CAS:Produto Controlado<p>Applications Chloramphenicol Succinate Sodium is a derivative of Chloramphenicol (C325030) which are broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.<br>References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),<br></p>Fórmula:C15H15Cl2N2O8·NaPureza:>90%Cor e Forma:NeatPeso molecular:445.18L-Cycloserine
CAS:Produto Controlado<p>Applications L-Cycloserine is an irreversible inhibitor of 3-ketodihydrosphingosine synthetase.<br></p>Fórmula:C3H6N2O2Cor e Forma:NeatPeso molecular:102.09Azithromycin-d5
CAS:Produto Controlado<p>Applications Azithromycin-d5, is the labeled analogue Azithromycin (A927000), a semi-synthetic macrolide antibiotic; related to Erythromycin A. Antibacterial.<br>References Langtry, H.D., et al.: Drugs, 56, 273 (1998),<br></p>Fórmula:C38H67D5N2O12Cor e Forma:NeatPeso molecular:754.02Ledipasvir
CAS:<p>Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.</p>Fórmula:C49H54F2N8O6Pureza:99.96%Cor e Forma:SolidPeso molecular:88925-Desacetyl Rifampicin(>90%)
CAS:<p>Stability Light Sensitive<br>Applications A metabolite of Rifampicin.<br>References Blumenfeld,O.O., et al.: J. Biol. Chem., 236, 2472 (1961), Cowxan, R.A., et al.: Biochem. Biophys. Res. Commun, 23, 799 (1966)<br></p>Fórmula:C41H56N4O11Pureza:>90%Cor e Forma:NeatPeso molecular:780.90Tacrolimus (FK506)
CAS:<p>Applications An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Asano, K., et al.: In Vivo, 10, 537 (1996), McCall, E., et al.: Circ. Res., 79, 1110 (1996), Raufman, J.P., et al.: J. Biol. Chem., 271, 19877 (1996), Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318, 1104 (1999)<br></p>Fórmula:C44H69NO12Cor e Forma:NeatPeso molecular:804.02Clarithromycin N-Oxide
CAS:Produto Controlado<p>Impurity Clarithromycin EP Impurity Q<br>Applications Clarithromycin N-oxide (Clarithromycin EP Impurity Q) is an urinary metabolite of Clarithromycin (C559750), a macrolide antibiotic.<br>References Jones, P., et al.: J. Med. Chem., 15, 631 (1972), Watanabe, Y., et al.: J. Antibiot., 46, 647 (1983), Ohmori, S., et al.: Drug Metab. Dispos., 21, 358 (1993),<br></p>Fórmula:C38H69NO14Cor e Forma:Off-WhitePeso molecular:763.954-Nitrobenzaldehyde
CAS:<p>Applications 4-Nitrobenzaldehyde is a benzaldehyde with a nitro group in the para position. It is used as a reagent in decarboxylative aldol reactions that are catalyzed by lipases and proteases in organic co-solvent mixtures.<br>References Chaurasia, P.K., et al.: Synthetic Commun., 44, 2535 (2014); Ishikawa, F., et al.: Bioorg. Med. Chem., 21, 7011 (2013); Jiang, L., et al.: Biotechnol. Lett., 36, 99 (2014)<br></p>Fórmula:C7H5NO3Cor e Forma:NeatPeso molecular:151.12Oleandomycin
CAS:<p>Applications Antibiotic substance produced by Streptomyces antibioticus no. ATCC 11891. Antibacterial.<br>References Sous, H., et al.: Arzneim.-Forsch., 8, 386 (1958), Hahn, et al.: Antibiotics, 1, 378 (1967),<br></p>Fórmula:C35H61NO12Cor e Forma:NeatPeso molecular:687.86Aztreonam
CAS:Produto Controlado<p>Applications The first totally synthetic monocyclic β-lactam antibiotic.<br>References Sykes, R.B., et al.: Antimicrob. Agents Chemother., 21, 85 (1982), Florey, K., et al.: Anal. Profiles Drug Subs., 17, 1 (1988),<br></p>Fórmula:C13H17N5O8S2Cor e Forma:WhitePeso molecular:435.43Florfenicol-d3
CAS:Produto Controlado<p>Applications Labelled Florfenicol (F405750). Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.<br>References Kim, E and Aoki, T.: Microbiol. Immunol., 40, 665, (1996), Keyes, K.: Antimicrob. Agents Chemother., 44, 421 (2000)<br></p>Fórmula:C12D3H11Cl2FNO4SCor e Forma:Off White SolidPeso molecular:361.23Spiramycin
CAS:Produto Controlado<p>Applications Spiramycin is a macrolide antibiotics.<br>References Patil, S., et al.: World J. Pharm. Res., 5, 1529 (2016)<br></p>Fórmula:C43H74N2O14Cor e Forma:WhitePeso molecular:843.05N,N-bis(1-naphthylmethyl)aminomethane
CAS:Produto Controlado<p>Applications N-Methyl-N-(1-naphthalenylmethyl)-1-naphthalenemethanamine is a reagent used in the synthesis of Butenafine Hydrochloride (B690195) an anti-fungal.<br>References Maeda, T., et al.: Yakugaku Zasshi, 111, 126 (1991).<br></p>Fórmula:C23H21NCor e Forma:NeatPeso molecular:311.42Virginiamycin(>85%)
CAS:Produto ControladoFórmula:C43H49N7O10C28H35N3O7Pureza:>85%Cor e Forma:Light Yellow To Dark BrownPeso molecular:1349.5125-Desacetyl Rifapentin
CAS:Produto ControladoFórmula:C45H62N4O11Cor e Forma:NeatPeso molecular:834.99Nebramine Hydrochloride
CAS:<p>Stability Very Hygroscopic<br>Applications Nebramine is a degradation product of the antibiotic Tobramycin (T524000).<br>References Brandl, M. et al.: Drug Dev. Indust. Pharm., 18, 1423 (1992); Ghinami, C. et al.: J. Chrom. A, 1139, 52 (2007)<br></p>Fórmula:C12H26N4O5·(ClH)xPureza:>90%Cor e Forma:Off White To Light BrownPeso molecular:306.363646Rifabutin N-Oxide
CAS:Produto Controlado<p>Stability Hygroscopic, Light Sensitive<br>Applications Rifabutin N-Oxide is a metabolite of Rifabutin (R505000) and like its parent compound it exhibits antibacterial activity.<br>References Medeiros, M., et al.: PCT Int. Appl., 44, (2004); Anand, R., et al.: Antimicrob. AG. Chemother., 32 (684 (1988), Skinner, M.H., et al.: Antimicrob. Agent Chemother., 33, 1237 (1989),<br></p>Fórmula:C46H62N4O12Cor e Forma:Dark RedPeso molecular:863.00FK-506-13C,D2 (Major) (Tacrolimus) (>85%)
CAS:Produto ControladoFórmula:CC43D2H67NO12Pureza:>85%Cor e Forma:NeatPeso molecular:807.027-Dechloro Griseofulvin
CAS:Produto Controlado<p>Applications A major photoproduct (impurity) of Griseofulvin (G787500).<br>References Mantle, P., et al.: J. Gen. Microbiol., 130, 1293 (1984), Boonphong, S., et al.: J. Nat. Prod., 64, 965 (2001),<br></p>Fórmula:C17H18O6Cor e Forma:NeatPeso molecular:318.32Cefaclor Monohydrate
CAS:Produto Controlado<p>Applications Second-generation cephalosporin antibiotic. Antibacterial.<br>References Gray, B.M., et al.: Antimicrob. Agents Chemother., 13, 988 (1978), Lorenz, L.J., et al.: Anal. Profiles Drug Subs., 9, 107 (1980), Hori, R., et al.: J. Pharm. Pharmacol., 40, 646 (1988),<br></p>Fórmula:C15H14ClN3O4S·H2OCor e Forma:NeatPeso molecular:385.82Ivermectin-d2
CAS:Produto Controlado<p>Applications Isotope labelled Ivermectin, is the labeled analogue of Ivermectin (I940800), which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980), Campbell, W.C., et al.: Science, 221, 823 (1983), Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988), Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995), ; Caly, L., et al.: Antivir. Res., 178<br></p>Fórmula:C48H72D2O14Cor e Forma:NeatPeso molecular:877.117-Aminodesacetoxycephalosporanic Acid
CAS:<p>Impurity Cefadroxil EP Impurity B<br>Applications 7-Aminodesacetoxycephalosporanic Acid (Cefadroxil EP Impurity B) is a metabolite of Cephalexin (C256800).<br>References Dantzig, A., et al.: Biochim. Biophys. Acta, 1027, 211 (1990), Shen, H., et al.: J. Biol. Chem., 278, 4786 (2003), Watanabe, C., et al.: Drug Metab. Pharmacokinet., 20, 443 (2005)<br></p>Fórmula:C8H10N2O3SCor e Forma:BeigePeso molecular:214.2425-Deacetyl-21-acetyl Rifampicin
CAS:<p>Applications 25-Deacetyl-21-acetyl Rifampicin is a structural isomer, and impurity, of Rifampicin (R508000), a semisynthetic antibiotic. Antibacerial (tuberculostatic).<br>References Furesz, et al.: Antibiot. Chemother., 16, 316 (1970), Gallo, G.G., et al.: Anal. Profiles Drug Subs., 5, 467 (1976),<br></p>Fórmula:C43H58N4O12Cor e Forma:NeatPeso molecular:822.94Desfuroyl Ceftiofur (>85%)
CAS:Produto Controlado<p>Stability Hygroscopic, Temperature Sensitive<br>Applications A metabolite of Ceftiofur (C244700), which is microbiologic active.<br>References Washburn, K., et al.: J. Vet. Pharm. Ther., 28, 247 (2005),<br></p>Fórmula:C14H15N5O5S3Pureza:>85%Cor e Forma:BeigePeso molecular:429.49(Z)-Desbutyl Lumefantrine
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications (Z)-Desbutyl Lumefantrine is a metabolite of Lumefantrine (L474000).<br>References Lefevre, G., et al.: Br. J. Clin. Pharmacol., 54, 485 (2002); Schepers, U., et al.: J. Pharm. Biomed. Anal., 310 (2005)<br></p>Fórmula:C26H24Cl3NOCor e Forma:NeatPeso molecular:472.83rac Cycloserine-15N,d3
CAS:Produto Controlado<p>Applications Labelled Cycloserine. Antibacterial (tuberculostatic).<br>References Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972), Gentry-Weeks, C., et al.: J. Biol. Chem., 268, 7298 (1993), Alexander, F., et al.: Eur. J. Biochem., 219, 953 (1994), Auger, S., et al.: Biochimie, 87, 231 (2005),<br></p>Fórmula:C3H3D3N15NO2Cor e Forma:NeatPeso molecular:106.1Lumefantrine
CAS:Produto Controlado<p>Applications Inhibits hemozoin formation. Antimalarial.<br>References Kumar, N., et al.: Parasitol Res., 76, 214 (1990), Pradines, B., et al.: Antimicrob. Agents Chemother., 43, 418 (1999), Chotivanich, K., et al.: J. Infect. Dis., 182, 629 (2000), Mutabingwa, T., et al.: Lancet, 365, 1474 (2005),<br></p>Fórmula:C30H32Cl3NOCor e Forma:Light YellowPeso molecular:528.94β-Apo-oxytetracycline (>80%)
CAS:Produto Controlado<p>Stability Unstable in basic solution<br>Applications Oxytetracycline metabolite (absolute stereochemistry unknown)<br>References Mackie, R., et al.: Animal Biotechnol., 17, 157 (2006), Smyrniotakis, C., et al.: J. Pharm. Biomed. Anal., 43, 506 (2007), Li, D., et al.: Env. Toxicol. Chem., 27, 80 (2008),<br></p>Fórmula:C22H22N2O8Pureza:>80%Cor e Forma:NeatPeso molecular:442.42Aztreonam Ethyl Ester
CAS:Produto ControladoFórmula:C15H21N5O8S2Cor e Forma:NeatPeso molecular:463.486Ciprofloxacin
CAS:<p>Applications Fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Hoffken, G., et al.: Antimicrob. Ag. Chemother., 27, 375 (1985), Scully, B.E., et al.: Lancet, 1, 819 (1986)<br></p>Fórmula:C17H18FN3O3Cor e Forma:NeatPeso molecular:331.34Dihydro FK-506
CAS:Produto Controlado<p>Impurity Tacrolimus 8-Propyl Analog (USP)<br>Applications A novel analog of FK-506 (F370000) macrocycle.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kino, T., et al.: J. Antibiot., 40, 1249 (1987), Motamedi, H., et al.: J. Bacteriol., 178, 5243 (1996), Dai, Y., et al.: Drug Metab. Dispos., 34, 836 (2006),<br></p>Fórmula:C44H71NO12Cor e Forma:NeatPeso molecular:806.032-NP-AMOZ
CAS:<p>Applications A derivatized of AMOZ (A634600), a metabolite of Nitrofuran.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Vroomen, L., et al.: Toxicol. Appl. Pharmacol., 95, 53 (1988), Delatour, T., et al.: J. Agric. Food Chem., 51, 6371 (2003), Stadler, R., et al.: Analyst, 129, 276 (2004),<br></p>Fórmula:C15H18N4O5Cor e Forma:NeatPeso molecular:334.332H,5H-Pyrano[4,3-b]pyranyl Mupirocin Sodium Impurity
CAS:Produto Controlado<p>Impurity Mupirocin EP Impurity E<br>Stability Hygroscopic<br>Applications Mupirocin (M794000) impurity. The rearrangement isomer of Mupirocin is prepared using an enzyme-catalyzed, selective deesterification.<br>References Sime, J.T., et al.: Tetrahedron Lett., 28, 5169 (1987),<br></p>Fórmula:C26H43O9·NaCor e Forma:Off WhitePeso molecular:522.60Meropenem-d6 (>90%)
CAS:Produto Controlado<p>Stability Unstable in Solution<br>Applications Meropenem-d6 is the labeled analogue of Meropenem, a carbapenem antibiotic. Antibacterial.<br>References Adams, M.D., et al.: J. Bacteriol., 190, 8053 (2008); Pattanaik, P., et al.: J. Biol. Chem., 284, 945 (2009); Mendes, R., et al.: J. Antimicrob. Chemother., 63, 55 (2009)<br></p>Fórmula:C17H19D6N3O5SPureza:>90%Cor e Forma:White To Light YellowPeso molecular:389.5Ledipasvir
CAS:<p>Applications Ledipasvir is most commonly used in combination with sofosbuvir for treatment in chronic hepatitis C genotype 1 patients. It inhibits an important viral phosphoprotein, NS5A, which is involved in viral replication, assembly, and secretion.<br>References Lawitz, E., et al.: J. Hepatol., 57, 24 (2012); Afdhal, N., et al.: New England J. Med., 370, 1889 (2014)<br></p>Fórmula:C49H54F2N8O6Cor e Forma:White To Light BeigePeso molecular:889.003-Chloro-D-alanine Methyl Ester Hydrochloride
CAS:Produto Controlado<p>Applications 3-Chloro-D-alanine Methyl Ester Hydrochloride is an intermediate in the preparation of antibiotic D-Cycloserine (C988815) which inhibits cell wall biosynthesis in bacteria.<br>References Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972); Gentry-Weeks, C., et al.: J. Biol. Chem., 268, 7298 (1993); Alexander, F., et al.: Eur. J. Biochem., 219, 953 (1994); Auger, S., et al.: Biochimie, 87, 231 (2005); Chem and Eng. News p. 12, Dec. 7/14 (2015);<br></p>Fórmula:C4H8ClNO2·HClCor e Forma:NeatPeso molecular:137.56+(36.46)3,4-Dihydro Ivermectin (Mixture of Diastereomers) (>90%)
CAS:Produto Controlado<p>Impurity Ivermectin EP Impurity K<br>Applications 3,4-Dihydro Ivermectin is an impurity of Ivermectin (I940800), an antiparasitic drug that is active against a wide variety of nematode and arthropod parasites and is used to treat scabies and lice in humans. An invitro inhibitor of SARS-CoV-2/ Covid-19.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Campbell, W., et al.: Science, 221, 823 (1983); Glaziou, P., et al.: Trop. Med. Parasitol., 45, 253 (1994); Meinking, T., et al.: New Engl. J. Med., 333, 26 (1995); Caly, L., et al.: Antivir. Res., 178<br></p>Fórmula:C48H76O14Pureza:>90%Cor e Forma:NeatPeso molecular:877.11Hygromycin B Deuterated (d4 major)
CAS:Produto ControladoFórmula:C20H33D4N3O13Cor e Forma:NeatPeso molecular:531.54Tigecycline
CAS:<p>Stability Light Sensitive<br>Applications A glycylcycline antibiotic, used to treat infection by drug resistant bacteria such as Staphylococcus aureus (Staph aureus) and Acinetobacter baumannii.<br>References Lim, T., et al.: J. Antibiotics, 62, 675 (2009), Presterl, E., et al.: Antimicrob. Agents Chemother., 53, 3205 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),<br></p>Fórmula:C29H39N5O8Cor e Forma:OrangePeso molecular:585.65N-Formyl-3-mercaptovaline
CAS:<p>Stability Air Sensitive<br>Applications N-Formyl-3-mercaptovaline acts as a reagent in the preparation of derivatives of D-penicillamine as potential antiarthritic agents.<br>References Reich, M. F., et al.: Bioorg. Med. Chem. Lett., 4, 1167 (1994)<br></p>Fórmula:C6H11NO3SCor e Forma:White To Off-WhitePeso molecular:177.22Erythromycin Estolate (>85%)
CAS:Produto Controlado<p>Applications Used as an antibacterial agent. LD50 >5000 mg/kg for oral administration to rats.<br>References Goldenthal, E.I.: Toxicol. Appl. Pharmacol., 18, 185 (1971)<br></p>Fórmula:C40H71NO14·C12H26O4SPureza:>85%Cor e Forma:WhitePeso molecular:1056.39L-(+)-threo-Chloramphenicol
CAS:Produto Controlado<p>Applications The S,S-stereoisomer of Chloramphenicol (C325030). Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.<br>References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),<br></p>Fórmula:C11H12Cl2N2O5Cor e Forma:NeatPeso molecular:323.138-Fluoro-6-methoxy Moxifloxacin Dihydrochloride
CAS:Produto Controlado<p>Impurity Moxifloaxacin EP Impurity D<br>Stability Hygroscopic<br>Applications 8-Fluoro-6-methoxy Moxifloxacin Dihydrochloride (Moxifloaxacin EP Impurity D) is an impurity of Moxifloxacin (M745000).<br>References Martel, A., et al.: Drugs Fut., 22, 109 (1997), Tobin, C., et al.: J. Antimicrob. Chemother., 42, 278 (1998),<br></p>Fórmula:C21H26Cl2FN3O4Cor e Forma:NeatPeso molecular:474.35Anidulafungin
CAS:<p>Applications Anidulafungin, is a semisynthetic echinocandin that inhibits glucan synthase, an enzyme important in the formation of (1→3)-β-D-glucan, a major fungal cell wall component, and thus is used as antifungal drug.<br>References Denning, D. W., et al.: J. Antimicrob. Chemother, 40, 611 (1997); Vazquez, J. A., et al.: Clin. Ther., 27(6), 657 (2005);<br></p>Fórmula:C58H73N7O17Cor e Forma:White To Light BeigePeso molecular:1140.24Desmycosin
CAS:Produto Controlado<p>Applications Desmycosin is a 16-membered macrolide antibiotic and a metabolite of Tylosin (T947650). Desmycosin is also a precursor to Tilmicosin (T440500).<br>References Wal, J.M. et al.: J. Antibiot., 26, 687 (1973); Hu, D. et al.: Environ. Toxicol. Chem., 26, 884 (2007); Min, Y. et al.: Proc. Biochem., 42, 729 (2007);<br></p>Fórmula:C39H65NO14Cor e Forma:White To Light BeigePeso molecular:771.93δ2-Ceftazidime (>80%)
CAS:Produto Controlado<p>Impurity Ceftazidime EP Impurity A<br>Stability Hygroscopic, Light Sensitive<br>Applications ∆2-Ceftazidime, 90% (Ceftazidime EP Impurity A) is a Ceftazidime isomer, an impurity of Ceftazidime (C244100).<br>References Vilanova, B., et al.: Helv. Chim. Acta, 76, 2789 (1993), Zhou, M., et al.: J. Pharm. Sci., 84, 534 (1995), Baertschi, S., et al.: Chemother. 8, 353 (1997), Porra, R., et al.: J. Pharm. Biomed. Anal., 18, 241 (1998),<br></p>Fórmula:C22H22N6O7S2Pureza:>80%Cor e Forma:White To BrownPeso molecular:546.58Ciprofloxacin Piperazinyl-N4-sulfate
CAS:<p>Applications A metabolite of the fluorinated quinolone antibacterial Ciprofloxacin (C482500).<br>References Hoffken, G., et al.: Antimicrob. Ag. Chemother., 27, 375 (1985), Scully, B.E., et al.: Lancet, 1, 819 (1986)<br></p>Fórmula:C17H18FN3O6SCor e Forma:NeatPeso molecular:411.40Meropenem Dimer Impurity Sodium Salt (>90% purity)(Mixture of double bond isomers)
CAS:Produto ControladoFórmula:C34H50N6O10S2·xNaCor e Forma:NeatPeso molecular:766.92 + x(22.99)De(cladinosyl) Clarithromycin
CAS:Produto Controlado<p>Impurity Clarithromycin EP Impurity I<br>Applications De(cladinosyl) Clarithromycin (Clarithromycin EP Impurity I) is an impurity of Clarithromycin (C559750). De(cladinosyl) Clarithromycin showed significantly potent antibacterial activity against community acquired respiratory pathogens.<br>References Morimoto, S., et al.: J. Antibiot., 37, 187 (1984), Buxbaum, A., et al.: J. Antimicrob. Chemother., 52, 371 (2003), Westphal, J., et al.: Br. J. Clin. Pharmacol., 50, 285 (2000), Ma, Z., et al.: J. Med. Chem., 44, 4137 (2001),<br></p>Fórmula:C30H55NO10Cor e Forma:White To Off-WhitePeso molecular:589.76Lumefantrine-d18
CAS:Produto Controlado<p>Applications Inhibits hemozoin formation. Antimalarial.<br>References Kumar, N., et al.: Parasitol Res., 76, 214 (1990), Pradines, B., et al.: Antimicrob. Agents Chemother., 43, 418 (1999), Chotivanich, K., et al.: J. Infect. Dis., 182, 629 (2000), Mutabingwa, T., et al.: Lancet, 365, 1474 (2005),<br></p>Fórmula:C30H14D18Cl3NOCor e Forma:NeatPeso molecular:547.05Aztreonam-d6
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Isotope labelled Aztreonam (A965200), the first totally synthetic monocyclic β-lactam antibiotic.<br>References Sykes, R.B., et al.: Antimicrob. Agents Chemother., 21, 85 (1982), Florey, K., et al.: Anal. Profiles Drug Subs., 17, 1 (1988),<br></p>Fórmula:C13H11D6N5O8S2Cor e Forma:NeatPeso molecular:441.47Methyl 1-Thiolincosaminide
CAS:Produto Controlado<p>Applications Intermediate in the production of biosynthetic antibiotics<br>References Horton, D., et al.: Anal. Biochem., 59, 452 (1974), Kamenik, Z., et al.: Anal. Bioanal. Chem., 393, 1779 (2009),<br></p>Fórmula:C9H19NO5SCor e Forma:NeatPeso molecular:253.32Ceftazidime Hydrate (~5% Sodium Carbonate as stabilizer)
CAS:Produto ControladoFórmula:C22H22N6O7S2·x(H2O)Cor e Forma:NeatPeso molecular:546.58+x(18.02)Erythromycin Lactobionate
CAS:Produto Controlado<p>Applications Erythromycin Lactobionate is an antibiotic used to reduce the prevalence of drug resistant bacteria as well as keeping constant the efficacy of other antibacterial drugs.<br>References Kiso, S. et al.: Anticanc. Res., 20, 2827 (2000); Broad, J. et al.: Brit. J. Pharm., 168,1859 (2013); Itoh, Z., et al.: Antimicrob. Agents Chemother., 26, 863(1984)<br></p>Fórmula:C37H67NO13·C12H22O12Cor e Forma:NeatPeso molecular:1092.22Chloramphenicol-d5 (100Mug/mL in Acetonitrile)
CAS:Produto ControladoFórmula:C11H7D5Cl2N2O5Cor e Forma:ColourlessPeso molecular:328.16Tacrolimus Hydrate
CAS:<p>Applications Tacrolimus Hydrate is a disease-modifying antirheumatic drugs (DMARDs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ogasawara, M., et al.: Mod. Rheumatol., 22, 831-836 (2012)<br></p>Fórmula:C44H69NO12·H2OCor e Forma:NeatPeso molecular:822.037-Amino-3-vinyl-3-cephem-4-carboxylic Acid
CAS:Produto Controlado<p>Applications A key intermediate in the manufacturing of Cephalosporin compounds.<br>References Choi, K., et al.: J. Antibio., 50, 279 (1997),<br></p>Fórmula:C9H10N2O3SCor e Forma:NeatPeso molecular:226.254-Methoxybenzyl 3-Chloromethyl-7-(2-phenylacetamido)-3-cephem-4-carboxylate
CAS:Produto Controlado<p>Applications A key intermediate of cephem compounds.<br>References Chambers, H., et al.: Antimicrob. Agents Chemother., 39, 2620 (1995), Heinisch, L., et al.: J. Med. Chem., 45, 3032 (2002),<br></p>Fórmula:C24H23ClN2O5SCor e Forma:NeatPeso molecular:486.97Amoxicillin Dimer tri-Sodium Salt (penicilloic acid form)(Mixture of Diastereomers)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Amoxicillin dimer tri-Sodium Salt (penicilloic acid form) is an impurity of Amoxicillin (A634235), a β-lactam family antibiotic that is commonly used in conjunction with clavulanic acid (C56370) to the treat bacterial infections.<br>References Gurwith, M., et al.: Antimicrob. Agents Ch., 24, 716 (1983); Kumar, A., et al.: J. Mater. Chem., 20, 10152 (2010);<br></p>Fórmula:C32H37N6Na3O11S2Cor e Forma:NeatPeso molecular:814.77N-Nitroso Moxifloxacin
Produto ControladoFórmula:C21H23FN4O5Cor e Forma:Off-White To Light YellowPeso molecular:430.43Roxithromycin
CAS:<p>Applications Semisynthetic Erythromycin derivative. Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Jones, R.N., et al.: Antimicrob. Agents Chemother., 24, 209 (1983), Barry, A.L., et al.: Eur. J. Clin. Microbiol., 5, 536 (1986), Grassi, C., et al.: Chemioterapia, 6, 41 (1987),<br></p>Fórmula:C41H76N2O15Cor e Forma:White To Off-WhitePeso molecular:837.053’’-HABA Kanamycin A Sulfate
CAS:Produto Controlado<p>Applications Amikacin (A578500) impurity C (EP).<br>References Naito, T., et al.: J. Antibiot., 26, 297 (1973), Weber, A., et al.: Clin. Microbiol., 21, 419 (1985),<br></p>Fórmula:C22H43N5O13xH2SO4Cor e Forma:NeatPeso molecular:585.6Rifampicin N-4’-Oxide
CAS:Produto Controlado<p>Applications Rifampicin N-4’-Oxide is a metabolite of Rifampicin (R508000).<br>References Gryaznova, N.S. et al.: Curr. Chemother. Immunother., Proc. Int. Congr. Chemother., 12, 984 (1982); Subbotina, N.A. et al.: Antibiotiki, 24, 590 (1979);<br></p>Fórmula:C43H58N4O13Cor e Forma:NeatPeso molecular:838.947-Epiclindamycin 2-Phosphate (>90%)
CAS:<p>Impurity Clindamycin Phosphate EP Impurity L<br>Applications 7-Epiclindamycin 2-Phosphate (Clindamycin Phosphate EP Impurity L) is an impurity of Clindamycin (C580000), a semi-synthetic antibiotic prepared from Lincomycin. Antibacterial.<br>References Birkenmeyer, R.D., et al.: J. Med. Chem., 13, 616 (1970); Oesterling, et al.: J. Pharm. Sci., 59, 63 (1970); Gray, J.E., et al.: Toxicol. Appl. Pharmacol., 21, 516 (1972); Brown, L.W., et al.: Anal. Profiles Drug Subs., 10, 75 (1981)<br></p>Fórmula:C18H34ClN2O8PSPureza:>90%Cor e Forma:White To Off-WhitePeso molecular:504.96Erythromycin-d3
CAS:Produto Controlado<p>Applications Isotope labelled Erythromycin (E649950), an antibiotic useful for the treatment of a number of bacterial infection, usually prescribed to patients with allergy to penicillin.<br>References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),<br></p>Fórmula:C37H64D3NO13Cor e Forma:NeatPeso molecular:736.96Netilmicin Sulfate
CAS:<p>Stability Hygroscopic<br>Applications Semisynthetic aminoglycoside antibiotic, related to sisomicin. Antibacterial.<br>References Miller, G.H., et al.: Antimicrob. Agents Chemother., 10, 827 (1976), Raab, W., et al.: Adv. Clin. Pharmacol., 15, 91 (1978), Noone, P., et al.: Drugs, 27, 548 (1984),<br></p>Fórmula:C21H41N5O7·5H2O4SCor e Forma:Light YellowPeso molecular:1441.55Terbinafine-d7 Hydrochloride
CAS:Produto Controlado<p>Applications An orally active, antimycotic allylamine related to naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Petranyi, G., et al.: Science, 224, 1239 (1984), Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985), Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999),<br></p>Fórmula:C21H18D7N·HClCor e Forma:NeatPeso molecular:334.93Erythromycin Ethyl Succinate
CAS:Produto Controlado<p>Applications Erythromycin Ethyl Succinate is a derivative of Erythromycin (E649950), an antibiotic.<br>References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979); Serisier, D. et al.: J. Am. Med. Assoc., 309, 1206 (2013);<br></p>Fórmula:C43H75NO16Cor e Forma:Off-WhitePeso molecular:862.05δ4-Cephalexin Diketopiperazine (Technical Grade)
CAS:Produto ControladoFórmula:C16H17N3O4SCor e Forma:NeatPeso molecular:347.39Tobramycin Sulphate Salt
CAS:Fórmula:C18H37N5O9•x(H2O4S)Cor e Forma:NeatPeso molecular:467.51+x(98.08)Rapamycin-31,42-Diester Impurity
Produto ControladoFórmula:C61H95NO19Cor e Forma:NeatPeso molecular:1146.4Oxytetracycline-¹³CD₃ Hydrochloride (>85%)
CAS:Produto ControladoFórmula:CC21D3H21N2O9·HClPureza:>85%Cor e Forma:NeatPeso molecular:500.906Erythromycin
CAS:<p>Applications Erythromycin is an antibiotic.This compound is a contaminant of emerging concern (CECs).<br>References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979),<br></p>Fórmula:C37H67NO13Cor e Forma:WhitePeso molecular:733.93Formyl Ciprofloxacin
CAS:Produto Controlado<p>Applications A metabolite of the fluorinated quinolone antibacterial Ciprofloxacin.<br>References Tiefenbacher, E., et al.: J. Pharm. Sci., 83, 463 (1994), Parshikov, I., et al.: App. Microbiol. Biotechnol., 56, 474 (2001),<br></p>Fórmula:C18H18FN3O4Cor e Forma:NeatPeso molecular:359.35δ2-Cephalexin
CAS:<p>Impurity Cefalexin EP Impurity F<br>Applications Δ2-Cephalexin (Cefalexin EP Impurity F) is an isomeric impurity of the semi-synthetic antibiotic Cephalexin (C256800).<br>References Marincel, J. et al.: Acta Pharmacol Jugo., 38, 35 (1988); Hendrix, C. et al.: Arck. Pharm., 327, 215 (1994);<br></p>Fórmula:C16H17N3O4SCor e Forma:NeatPeso molecular:347.39Lovastatin Hydroxy Acid, Sodium Salt
CAS:Produto ControladoFórmula:C24H37O6·NaCor e Forma:NeatPeso molecular:444.54Cefetamet-d3
CAS:Produto Controlado<p>Applications Labelled Cefetamet is a third-generation cephalosporin antibiotic and the active agent of Cefeamet pivoxil (C242780) after hydrolysis.<br>References Bryson, H.M., et al.: Drugs., 45, 589 (1993); Sharma, R.K., et al.: Asian. J. Biochem. Pharmaceut. Res., 1, 443 (2011); Waters, N.J., et al.: Drug. Metabolism. Disposit., 38, 1159 (2010);<br></p>Fórmula:C14H12D3N5O5S2Cor e Forma:White To Off-WhitePeso molecular:400.459-Deoxo-9a-aza-9a-homo Erythromycin A (Desmethyl Azithromycin)
CAS:Produto Controlado<p>Impurity Azithromycin EP Impurity A<br>Applications 9-Deoxo-9a-aza-9a-homo Erythromycin A (Azithromycin EP Impurity A) is a novel intermediate of Azithromycin that acts as antibiotic.<br>References Krajacic, M.B., et al.: J. Antibiot., 58, 380 (2005),<br></p>Fórmula:C37H70N2O12Cor e Forma:NeatPeso molecular:734.9617-epi-Pimecrolimus (>80%)
CAS:Produto ControladoFórmula:C43H68ClNO11Pureza:>80%Cor e Forma:NeatPeso molecular:810.45Cefpirome Sulfate
CAS:Produto Controlado<p>Applications Fourth generation cephalosporin antibiotic.<br>References Kavi, J., et al.: J. Antimicrob. Chemother., 22, 911 (1988), Horstmann, G., et al.: Arzneim.-Forsch., 40, 1250 (1990),<br></p>Fórmula:C22H22N6O5S2·H2O4SCor e Forma:Yellowish CrystallinePeso molecular:612.66p-Hydroxy-(D)-phenylglycyl Amoxicillin (Technical Grade)
CAS:Produto Controlado<p>Impurity Amoxicillin EP Impurity G ; Amoxicillin USP Related Compound G<br>Applications p-Hydroxy-(D)-phenylglycyl Amoxicillin is a derivative of Amoxicillin (A634235) a semi-synthetic antibiotic related to Penicillin.<br>References Brogden, R.N., et al.: Drugs, 18, 169 (1979), Bird, A.E., et al.: Anal. Profiles Drug Subs. Excip., 23, 1 (1994),<br></p>Fórmula:C24H26N4O7SPureza:>85%Cor e Forma:WhitePeso molecular:514.55Deacetyl Linezolid
CAS:<p>Impurity Linezolid USP Related Compound C<br>Applications An impurity of Linezolid (L466500), as antimycobacterial agent. Linezolid USP Related Compound C.<br>References Sato, K., et al.: Eur. J. Pharmacol., 347, 231 (1998), Maignan, S., et al.: J. Med. Chem., 43, 3226 (2000), Tokuyama, R., et al.: Chem. Pharm. Bull., 49, 353 (2001),<br></p>Fórmula:C14H18FN3O3Cor e Forma:Off-White To Light YellowPeso molecular:295.31Amoxicilloic Acid Dimer (Mixture of Diastereomers)
CAS:<p>Stability Temperature Sensitive<br>Applications Amoxicilloic Acid Dimer is an impurity of Amoxicillin (A634528), a semi-synthetic antibiotic related to Penicillin.<br>References Brogden, R.N., et al.: Drugs, 18, 169 (1979);Bird, A.E., et al.: Anal. Profiles Drug Subs. Excip., 23, 1 (1994)<br></p>Fórmula:C31H40N6O9S2Cor e Forma:NeatPeso molecular:704.814-epi-Oxytetracycline
CAS:<p>Impurity Oxytetracycline Hydrochloride EP Impurity A<br>Stability Hygroscopic, Unstable in solution<br>Applications A metabolite of Oxytetracycline (OTC); also a Tetracycline analogue as inhibitor of amyloid fibrils.<br>References Eisner, H., et al.: J. Pharm. Exp. Ther., 142, 122 (1963), Nelis, H., et al.: Drug Metab. Dispos., 10, 142 (1982), Boecker, R., et al.: Drugs Exp. Clin. Res., 9, 813 (1983),<br></p>Fórmula:C22H24N2O9Cor e Forma:White To Off-WhitePeso molecular:460.43(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)-N-{[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]methyl}acetamide
CAS:Produto ControladoFórmula:C13H15N5O4S2Cor e Forma:NeatPeso molecular:369.42D-Serine
CAS:Produto Controlado<p>Applications A proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. Inhibitor of serine palmitoyltransferase. A neuromodulator.<br>References Junjaud, G. et al.: J. Neurochem., 98, 1159 (2006); Hanada, K. et al.: FEBS Lett., 474, 63 (2000); Pollegionni, L. et al.: Cell. Mol. Life Sci., 67, 2387 (2010);<br></p>Fórmula:C3H7NO3Cor e Forma:NeatPeso molecular:105.09Tilmicosin-d3
CAS:Produto Controlado<p>Applications Tilmicosin-d3 is the labeled analogue of Tilmicosin (T440500), a macrolide antibiotic structurally related to tylosin. Antibacterial.<br>References Debono, M., et al.: J. Antibiot., 42, 1253 (1989); Ose, E.E., et al.: Vet. Rec., 123, 367 (1988); Morck, D.W., et al.: J. Am. Vet. Med. Assoc., 202, 273 (1993)<br></p>Fórmula:C46H77D3N2O13Cor e Forma:White To Off-WhitePeso molecular:872.15Eprinomectin-13CD3
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Eprinomectin-13CD3 is an isotopic analog of Eprinomectin (E590050), a mixture of semi-synthetic Avermectins.<br>References Jones, T.K., et al.: J. Agric. Food Chem., 42, 1786 (1994), Arena, J.P., et al.: J. Parasitol., 81, 286 (1995),<br></p>Fórmula:CC49D3H72NO14Cor e Forma:White To Off-WhitePeso molecular:918.14Cefpodoxime Proxetil
CAS:<p>Applications An antibacterial. A broad spectrum, orally absorbed third generation cephalosporin, ester prodrug of the active free acid metabolite, Cefpodoxime.<br>References Fujimoto, K., et al.: J. Antibiot., 40, 370 (1987), Utsui, Y., et al.: Antimicrob. Agents Chemother., 31, 1085 (1987),<br></p>Fórmula:C21H27N5O9S2Cor e Forma:White To Light YellowPeso molecular:557.607-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid
CAS:Produto Controlado<p>Impurity Ciprofloxacin EP Impurity A; Enrofloxacin impurity A<br>Applications 7-Chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-quinoline-3-carboxylic Acid (Ciprofloxacin EP Impurity A) is a metabolite of Ciprofloxacin, a fluorinated quinolone antibacterial.<br>References Siefert, H.M., et al.: Arzneim.-Forsch., 36, 1496 (1986), Zhi, C., J. Med. Chem., 49, 1455 (2006), Trefi, S., et al.: J. Pharm. Biomed. Anal., 44, 743 (2007),<br></p>Fórmula:C13H9ClFNO3Cor e Forma:Off-White To Light YellowPeso molecular:281.67Moxidectin
CAS:<p>Applications Moxidectin is a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bisset, S.A. et al.: New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al.: Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al.: Int. J. Appl. Res. Vet. Med., 3, 49 (2005);<br></p>Fórmula:C37H53NO8Cor e Forma:White To Off-WhitePeso molecular:639.82D-Penicillamine Disulfide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications D-Penicillamine Disulfide is used in the treatment of neurodegenerative diseases such as Parkinson’s and Motor Neuron Disease. Inactivator of α1-antiproteinase, preventing deleterious effects of peroxynitrite.<br>References Peters, L. et al.: Xenobio., 25, 1013 (1994); Whiteman, M. et al.: Annals. Rheum. Dis., 55, 383 (1996);<br></p>Fórmula:C10H20N2O4S2Cor e Forma:NeatPeso molecular:296.41Deacetamide Linezolid Azide
CAS:Produto Controlado<p>Impurity Linezolid USP Related Compound A<br>Applications An impurity of Linezolid (L466500), as antimycobacterial agent. Linezolid USP Related Compound A.<br>References Sato, K., et al.: Eur. J. Pharmacol., 347, 231 (1998), Maignan, S., et al.: J. Med. Chem., 43, 3226 (2000), Tokuyama, R., et al.: Chem. Pharm. Bull., 49, 353 (2001),<br></p>Fórmula:C14H16FN5O3Cor e Forma:NeatPeso molecular:321.31Azithromycin N-Ethyl
CAS:Produto Controlado<p>Impurity Azithromycin Related Compound O<br>Applications Azithromycin N-Ethyl is an analogue of Azithromycin (A927000), an semi-synthetic macrolide antibiotic that is related to Erythromycin (E649950).<br>References Bright, G.M., et al.: J. Antibio., 41, 1029 (1988);<br></p>Fórmula:C39H74N2O12Cor e Forma:NeatPeso molecular:763.017-O-Demethyl Rapamycin (~80%)
CAS:<p>Applications Rapamycin metabolite.<br>References Dickman, D., et al.: Bioorg. Med. Chem. Lett., 10, 1405 (2000), Davis, D., et al.: Clin. Biochem., 33, 31 (2000), Cummins, C., et al.: J. Pharmacol. Exper. Ther., 308, 143 (2004), Scholer, A., et al.: Clin. Lab., 52, 325 (2006),<br></p>Fórmula:C50H77NO13Pureza:~80%Cor e Forma:NeatPeso molecular:900.152-(Dibutylamino)-1-(2,7-dichloro-9H-fluoren-4-yl)ethanol
CAS:<p>Applications 2-(Dibutylamino)-1-(2,7-dichloror-9H-fluoren-4-yl)ethanol is an impurity formed during the synthesis of Lumefantrine (L474000), a fluorene (F462000) derivative belonging to the aryl amino alcohol class of anti-malarial drugs.<br>References Verbeken, M., et al.: Malaria. J., 10, 51 (2011); Kim, K.H., et al.: J. Med. Chem., 22, 366 (1979);<br></p>Fórmula:C23H29Cl2NOCor e Forma:NeatPeso molecular:406.39Erythromycin A N-oxide
CAS:Produto Controlado<p>Stability Sample is unstable in solution<br>Applications Erythromycin A N-oxide is a facile metabolite of erythromycin A.<br></p>Fórmula:C37H67NO14Pureza:>80%Cor e Forma:NeatPeso molecular:749.93Rifampicin-D3
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Semisynthetic antibiotic. Antibacerial (tuberculostatic).<br>References Furesz, et al.: Antibiot. Chemother., 16, 316 (1970), Gallo, G.G., et al.: Anal. Profiles Drug Subs., 5, 467 (1976),<br></p>Fórmula:C43H55D3N4O12Cor e Forma:RedPeso molecular:825.96(19E/Z)-seco Rapamycin Sodium Salt (>80%)
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A decomposition product of Rapamycin (R124000).<br>References Yatscoff, R.W., et all.: Ther. Drug Monit., 17, 666 (1995), Wacher, V.J., et al.: J. Pharm. Sci., 87, 1322 (1998),<br></p>Fórmula:C51H78NNaO13Pureza:>80%Cor e Forma:NeatPeso molecular:936.154Erythromycin Stearate
CAS:<p>Applications Semi-synthetic macrolide antibiotic. Antibacterial.<br>References Malmborg, A.-S., et al.: J. Antimicrob. Chemother., 5, 591 (1979),<br></p>Fórmula:C37H67NO13·C18H36O2Cor e Forma:NeatPeso molecular:1018.40Bacitracin Zinc (>80%)
CAS:Produto Controlado<p>Applications Bacitracin is a peptide antibiotic effective against gram-postive bacteria. Bacitracin is an inhibitor of peptidoglycan synthesis. Bacitracin disrupts bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Bacitracin also strongly inhibits proline endopeptidase from human muscle.<br>References Ward, J.B. et al.: Biochem. J., 141, 227 (1974); Anastasi, A. et al.: Biochem. J., 290, 601 (1993); Daly, D.J. et al.: Biochem. Soc. Trans., 13, 1161 (1985); Weinberg, E.D. et al.: Antibiot. Ber., 90, (1967);<br></p>Fórmula:C65H99N17O16S·ZnPureza:>80%Cor e Forma:Light Yellow To Off-WhitePeso molecular:1472.06Monodecarboxy Piperacilloic Acid (Mixture of Diastereomers)
CAS:Produto Controlado<p>Impurity Piperacillin EP Impurity C<br>Stability Hygroscopic<br>Applications Monodecarboxy Piperacilloic Acid (Piperacillin EP Impurity C) is an impurity of Piperacillin (P479950), a β-lactam antibiotic.<br>References Saikawa, I. et al.: Yakug. Zas., 97, 995 (1977); Saikawa, I. et al.: Yakug. Zas., 97, 1071 (1977); Takano, S. et al.: Yakug. Zas., 97, 1064 (1977);<br></p>Fórmula:C22H29N5O6SCor e Forma:Off White SolidPeso molecular:491.561Lufenuron
CAS:<p>Applications Lufenuron is a benzoylurea pesticide which inhibits the production of chitin in larval fleas.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dryden, M.W.,et al.: Int. J. App. Res. Veterrin. Med., 10, 198 (2012); Malhat, F., et al.: Bull. Environ. Contamin. Toxicol., 89, 1037 (2012);<br></p>Fórmula:C17H8Cl2F8N2O3Cor e Forma:NeatPeso molecular:511.15Erythromycin A Enol Ether
CAS:<p>Impurity Erythromycin EP Impurity E<br>Applications Erythromycin A Enol Ether (Erythromycin EP Impurity E) is an impurity of Erythromycin.<br>References McGuire, J.M., et al.: Antibiot. Chemother., 6, 281 (1952), Steffansen, B., et al.: Int. J. Pharm., 56, 159 (1989), Goldman, R.C., et al.: Antimicrob. Agents Chemother., 34, 1973 (1990),<br></p>Fórmula:C37H65NO12Cor e Forma:Light YellowPeso molecular:715.91Epothilone D (synthetic)
CAS:Produto Controlado<p>Applications Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.<br>References Bollag, D.M., et al.: Cancer. Res., 55, 2325 (1995), Hardt, I.H., et al.: J. Nat. Prod., 64, 847 (2001), Gerth, K., et al.: J. Antibiot., 55, 41, 45 (2002)<br></p>Fórmula:C26H39NO5SCor e Forma:NeatPeso molecular:477.66T 2588G Sodium Bisulfite adduct
CAS:Produto Controlado<p>Applications T 2588G Sodium Bisulfite is a more stable form of T 2588G (Cefepime EP Impurity C) (T003100) which is a metabolite of Cefditorin (ME1207) (C242700), a new oral cephem.<br>References Sugioka, T., et al.: Chem. Pharmaceut. Bull., 38, 1998 (1990)<br></p>Fórmula:C8H11N4NaO6S2Cor e Forma:NeatPeso molecular:346.32Didechloro Vancomycin Hydrochloride (Technical Grade)(Vancomycin Impurity)
CAS:<p>Impurity Vancomycin Impurity<br>Applications An impurity in Vancomycin.A representative lot was 75% by HPLC with less than 0.1% vancomycin.<br>References Marshall, F.J., et al.: J. Med. Chem., 8, 18 (1965), Sheldrick, G.M., et al.: Nature, 271, 223 (1987), Dutca-Melan, S., et al.: J. Clin. Microbiol., 33, 24 (1995),<br></p>Fórmula:C66H77N9O24•x(HCl)Cor e Forma:Off White To Light YellowPeso molecular:1380.36 + x(36.46)Fumagillin
CAS:<p>Stability Light Sensitive<br>Applications Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-infective and antiangiogenic agent.<br>References Molina, J.M. et al.: N. Eng. J. Med., 346, 1963 (2002); Hou, L. et al.: Pathol. Int., 59, 448 (2009); Ingber, D. et al.: Nature, 348, 555 (1990);<br></p>Fórmula:C26H34O7Cor e Forma:NeatPeso molecular:458.54Clavulanic Acid
CAS:<p>Clavulanic Acid(RX-10100), a major beta-lactam antibiotic produced by the organism Streptomyces claveris, is a potent bacterial beta-lactamase inhibitor used in</p>Fórmula:C8H9NO5Pureza:98.25% - ≥98%Cor e Forma:SolidPeso molecular:199.16Amoxicillin Closed-loop Dimer
<p>Applications Amoxicillin Closed-loop Dimer is a dimer of Amoxicillin(A634528) which is an antibiotic used in the treatment of various bacterial infections.<br></p>Fórmula:C32H36N6O9S2Cor e Forma:NeatPeso molecular:712.793CP 1282 (>85%)
CAS:Produto Controlado<p>Applications CP 1282 is the tautomer of the antibiotic Cefotetan (C242970) with similar degradation rates.<br>References Koshiro, A. et al.: Chem. Pharm. Bull., 37, 1864 (1989); Naber, K. et al.: Zeitsch. Antmickrob. Antineoplast. Chemother., 2, 161 (1984);<br></p>Fórmula:C17H17N7O8S4Pureza:>85%Cor e Forma:NeatPeso molecular:575.62N-(3-Phthalimido-2-(R)-hydroxypropyl)-3-fluoro-4-(morpholinyl)aniline
CAS:Produto Controlado<p>Applications Linezolid (L466500) intermediate.<br></p>Fórmula:C21H22FN3O4Cor e Forma:Orange To Dark OrangePeso molecular:399.42Eprinomectin
CAS:<p>Applications A mixture of semi-synthetic Avermectins; containing 90% or more of component B1a and 10% or less of component B1b. Antiparasitic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jones, T.K., et al.: J. Agric. Food Chem., 42, 1786 (1994), Arena, J.P., et al.: J. Parasitol., 81, 286 (1995),<br></p>Fórmula:C50H75NO14·C49H73NO14Pureza:>85%Cor e Forma:White To Off-WhitePeso molecular:1814.23p-Hydroxypenicillin V (~90%)
CAS:<p>Stability Unstable in Solution<br>Applications p-Hydroxypenicillin V is a byproduct in the synthesis of Penicillin V (P223500), an antibacterial agent.<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Dunham, J.M., et al.: Anal. Profiles Drug Subs., 1, 249 (1972),<br></p>Fórmula:C16H18N2O6SPureza:~90%Cor e Forma:White To Off-WhitePeso molecular:366.396-Epi Doxycycline
CAS:<p>Impurity Doxycycline Related Compound A<br>Stability Hygroscopic, Light Sensitive, Temperature Sensitive<br>Applications 6-Epi Doxycycline is an antibiotic used in the treatment of bacterial and certain parasitic infections. Doxycycline Related Compound A<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jutglar, M., et al.: J. Pharm. Biomed. Anal., 159, 60 (2018); Metsemakers, W., et al.: J. Control. Release, 209, 47 (2015)<br></p>Fórmula:C22H24N2O8Pureza:>90%Cor e Forma:YellowPeso molecular:444.43Monensin Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Polyether antibiotic. Coccidiostat.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Day, et al.: Antimicrob. Agents Chemother., 4, 410 (1973), Buchko, S., et al.: J. Food Prot., 63, 1467 (2000), De Leener, E., et al.: Microb. Drug Resist., 10, 341 (2004), Sanderson, M., et al.: Vet. Microbiol., 110, 125 ( 2005),<br></p>Fórmula:C36H61O11·NaCor e Forma:BeigePeso molecular:692.85N-(1-Naphthylmethyl)methylamine Hydrochloride
CAS:Produto Controlado<p>Impurity Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications N-Methyl-1-naphthalenemethanamine hydrochloride (Terbinafine BP Impurity A; Terbinafine USP Related Compound A) is an intermediate used in the synthesis of various pharmaceuticals such as Terbinafine hydrochloride (T107500) and Butenafine hydrochloride (B690195).<br>References Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999); Kokjohn, K., et al.: Int. J. Dermatol., 42, 11 (2003); Sumikawa, M., et al.: J. Dermatol., 34, 456 (2007)<br></p>Fórmula:C12H13N·ClHCor e Forma:WhitePeso molecular:207.70Isochlortetracycline
CAS:Produto ControladoFórmula:C22H23ClN2O8Cor e Forma:Light Yellow To BeigePeso molecular:478.88α-Zearalenol
CAS:Produto ControladoFórmula:C18H24O5Cor e Forma:White To Light BeigePeso molecular:320.38Deacetamide Linezolid Phthalimide
CAS:Produto Controlado<p>Applications Linezolid (L466500) intermediate.<br></p>Fórmula:C22H20FN3O5Cor e Forma:White To Light Orange ColourPeso molecular:425.4111-Desmethyl Rifaximin
CAS:Produto Controlado<p>Applications 11-Desmethyl Rifaximin is a compound useful in organic synthesis.<br></p>Fórmula:C42H49N3O11Cor e Forma:NeatPeso molecular:771.85Mevastatin
CAS:Produto Controlado<p>Applications A fungal metabolite which is a potent inhibitor of HMG-CoA reductase.<br>References Endo, A., et al.: FEBS Letters, 72, 323 (1976), Endo, A.: J. Med. Chem., 28, 401 (1985)<br></p>Fórmula:C23H34O5Cor e Forma:White To Off-WhitePeso molecular:390.51Clarithromycin 9-Oxime (E/Z mixture)
CAS:<p>Stability Hygroscopic<br>Applications Clarithromycin 9-Oxime is an impurity of Clarithromycin (C559750), a macrolide antibiotic.<br>References Stephanic, V. et al.: J. Med. Chem., 54, 719 (2011); Chen, X. et al.: Zhong. Yao., 17, 32 (2008);<br></p>Fórmula:C38H70N2O13Cor e Forma:NeatPeso molecular:762.97N-Phenylacetylglycine
CAS:Produto Controlado<p>Applications A metabolite of carboxylic acid.<br>References Bardsley, W., et al.: Biochem. J., 122, 557 (1971), Kim, J., et al.: Biosci. Biotechnol. Biochem., 69, 1331 (2005), Kopka, J., et al.: J. Biotechnol., 124, 312 (2006),<br></p>Fórmula:C10H11NO3Cor e Forma:NeatPeso molecular:193.20
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