Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65580 produtos de "Derivados de Quinazolina e Quinolina"
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1,2,4-Triazol-4-amine
CAS:Produto Controlado<p>Applications 1,2,4-Triazol-4-amine is an intermediate used to prepare potent, selective, and orally active cyclooxygenase-2 inhibitors. It is also used to synthesize hydroxyphenacyl azoles and related azolium derivatives as antifungal agents.<br>References Song, Y., et al.: J. Med. Chem., 42, 1151 (1999); Emami, S., et al.: Bioorg. Med. Chem. Lett., 18. 141 (2008)<br></p>Fórmula:C2H4N4Cor e Forma:NeatPeso molecular:84.082-Azahypoxanthine Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 2-Azahypoxanthine is a major degradation product of Dacarbazine (D101400). 2-Azahypoxanthine is possibly linked with some adverse effects of Dacarbazine (D101400). AHX is a natural product that is produced by fungi that spurs the growth of grass.<br>References Baird, G., et al.: Lancet, 2, 681 (1978), Horton, J., et al.: J. Pharm. Pharmacol., 33, 808 (1981), Shetty, B., et al.: J. Pharm. Biomed. Anal., 10, 675 (1992); Chem. and Eng. News p.7 Oct.1, (2018)<br></p>Fórmula:C4H2N5NaOCor e Forma:NeatPeso molecular:159.08Ipragliflozin
CAS:Produto Controlado<p>Applications Ipragliflozin is a potent and selective inhibitor of sodium-glucose cotransporter-2 (SGLT2) and can serve as a potential agent for the treatment of type 1 and type 2 diabetes.<br>References Kadokura, T., et al.: Clin. Pharmacokinet., 53, 975 (2014); Kashiwagi, A., et al.: J. Diabetes Investig., 5, 382 (2014); Tahara, A., et al.: J. Pharm. Pharmacol., 66, 975 (2014); Zhang, W., et al.: Clin. Drug Invest., 33, 489 (2013)<br></p>Fórmula:C21H21FO5SCor e Forma:WhitePeso molecular:404.45Marbofloxacin-d8
CAS:Produto Controlado<p>Applications Labelled fluorinated quinolone antibacterial.<br>References Gruet, P., et al.: Vet. Rec., 140, 199 (1977), Lefebvre, H.P., et al.: J. Vet. Pharmacol. Ther., 21, 453 (1998),<br></p>Fórmula:C172H8H11FN4O4Cor e Forma:NeatPeso molecular:370.40Domperidone N-Oxide
CAS:Produto Controlado<p>Impurity Domperidone EP Impurity C<br>Stability Hygroscopic<br>Applications Domperidone N-Oxide (Domperidone EP Impurity C) is an oxygenated metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).<br>References Van Vaeck, L. et al.: Biomed. Env. Mass Spec., 16, 121 (1988);<br></p>Fórmula:C22H24ClN5O3Cor e Forma:White To Off-WhitePeso molecular:441.91[1,1'-Biphenyl]-4-yl(phenyl)methanol
CAS:Produto Controlado<p>Impurity Bifonazole EP Impurity A<br>Applications [1,1'-Biphenyl]-4-yl(phenyl)methanol (Bifonazole EP Impurity A) is a Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Fórmula:C19H16OCor e Forma:NeatPeso molecular:260.33(R)-3-Chloro-1-phenyl-1-(2-methylphenoxy)propane
CAS:Produto ControladoFórmula:C16H17ClOCor e Forma:NeatPeso molecular:260.761-(4-Chlorophenyl)-5-[6-[[4-[(4-chlorophenyl)amino]-6-[(1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl]-1,3,5-triazin-2-yl]amino]hexyl]biguanide D-Gluconic Acid
CAS:Produto ControladoFórmula:C28H38Cl2N10O5•C6H12O7Cor e Forma:NeatPeso molecular:665.57196162-pyrrolidin-1-yl-7-(2-thienyl)[1,3]thiazolo[4,5-d]pyridazin-4(5H)-one
CAS:Pureza:95.0%Peso molecular:304.3900146484375m-Ranolazine
CAS:Produto Controlado<p>Applications m-Ranolazine is an impurity of Ranolazine Ethyl Dimer is an impurity of Ranolazine (R122500), an anti-ischemic agent which modulates myocardial metabolism. Antianginal.<br>References Chaitman, B.R., et al.: J. Am. Coll. Cardial., 43, 1375 (2004), McCormack, J.G., et al.: Gen. Pharmacol., 30, 639 (1998), Schofield, J.A.H., et al.: Expert Opin. Invest. Drugs, 11, 117 (2002),<br></p>Fórmula:C24H33N3O4Cor e Forma:NeatPeso molecular:427.536N-(3-Morpholinopropyl) Gefitinib
CAS:Produto Controlado<p>Applications N-(3-Morpholinopropyl) Gefitinib is a Gefitinib (G304000) impurity. It can also be synthesized from O-Desmorpholinopropyl Gefitinib (D296830).<br>References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001); Hirata, A., et al.: Cancer Res., 62, 2554 (2002); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003); Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005); Ranson, M., et al.: J. Clin. Oncology, 20, 2240 (2002); Mendelsohn, J., et al.: J. Clin. Oncology, 21, 2787 (2003); McKillop, D., et al.: Xenobiotica, 10, 917 (2004);<br></p>Fórmula:C29H37ClFN5O4Cor e Forma:NeatPeso molecular:574.087Levosimendan
CAS:<p>Applications Bioactive enantiomer of racemate, Simendan. Positive inotropic agent with vasodilating activity. Cardiotonic.<br>References Sandell, E.-P., et al.: J. Cardiovasc. Pharmacol., 26, S57 (1995), Pagel, P.S., et al.: Cardiovasc. Drug Rev., 14, 286 (1996),<br></p>Fórmula:C14H12N6OCor e Forma:Yellow To Dark YellowPeso molecular:280.286'-Methoxy-2'-acetonaphthone (Naproxen Impurity L)
CAS:Produto Controlado<p>Impurity Naproxen USP Related Compound L<br>Applications Naproxen impurity L. Naproxen USP Related Compound L<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Li, J., et al.: J. Med. Chem., 39, 1846 (1996), Monser, L., et al.: J. Pharm. Biomed. Anal., 27, 851 (2002),<br></p>Fórmula:C13H12O2Cor e Forma:BeigePeso molecular:200.233(Z)-Thiothixene
CAS:Produto Controlado<p>Applications Thiothixene is a modulator of human P-glycoprotein and is frequently used a an anti-psychotic.<br>References Janowsky, D. et al.: J. Chlin. Psych., 67, 1272 (2006); Siegel, S. et al.: Eur. J. Pharm. Bioharm., 64, 287 (2006);<br></p>Fórmula:C23H29N3O2S2Cor e Forma:NeatPeso molecular:443.633-Hydroxybenzaldehyde
CAS:<p>Impurity Roxatidine Impurity 3<br>Applications 3-Hydroxybenzaldehyde (cas# 100-83-4) is a compound useful in organic synthesis.<br></p>Fórmula:C7H6O2Cor e Forma:Off-WhitePeso molecular:122.12β-(Cyanoimino)-1-piperidinepropanamide
CAS:Produto Controlado<p>Impurity Minoxidil EP Impurity C<br>Applications β-(Cyanoimino)-1-piperidinepropanamide (Minoxidil EP Impurity C) is an impurity in the synthesis of Minoxidil (M345000), used as an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Franz, T.J., et al.: Arch. Dermatol., 121, 203 (1985), Gadwood, R.C., et al.: Annu. Rep. Med. Chem., 24, 187 (1989), Hautala, T., et al.: Biochem. J., 283, 51 (1992),<br></p>Fórmula:C9H14N4OCor e Forma:NeatPeso molecular:194.233-Hydroxy-4-morpholino-1,2,5-thiazole
CAS:<p>Impurity Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D<br>Applications 3-Hydroxy-4-morpholino-1,2,5-thiazole (Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D) is an intermediate for the preparation of Timolol.<br>References Bodor, N., et al.: J. Med. Chem., 31, 100 (1988),<br></p>Fórmula:C6H9N3O2SCor e Forma:White To Off-WhitePeso molecular:187.22Tulobuterol-d9 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled Tulobuterol (T897250). A sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. A β-adrenergic receptor agonist, related structurally to Terbutaline (T109750).<br>References Kubo, S., et al.: Arzneim.-Forsch., 25, 1028 (1975), Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 44, 361 (1993), Qureshi, S., et al.: J. Exp. Med., 189, 615 (1999),<br></p>Fórmula:C122H9H9ClNO·ClHCor e Forma:White To Off WhitePeso molecular:273.25Hemiacetorphan
CAS:Produto Controlado<p>Applications Hemiacetorphan is an impurity of Racecadotril (R070600), which is antidiarrheal, enkephalinase inhibitor, and also capable of reducing the amount of water and electrolytes into the intestine.<br>References Cezard, J., et al.: Gastroenterol., 120, 799 (2001), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Lakshmana, P., et al.: J. Pharm. Res., 8, 39 (2009),<br></p>Fórmula:C14H17NO4SCor e Forma:NeatPeso molecular:295.355-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:329.4200134277344(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
CAS:Produto ControladoFórmula:C19H18IN3OCor e Forma:White To Light YellowPeso molecular:431.27Telmisartan
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Telmisartan is an angiotensin II receptor antagonist.<br>References Wienen, W., et al.: Brit. J. Pharmacol., 110, 245 (1993), Neutel, J.M., and Smith, D.H.G.: Adv. Ther., 15, 206 (1998)<br></p>Fórmula:C33H30N4O2Cor e Forma:NeatPeso molecular:514.62Pericyazine
CAS:Produto Controlado<p>Applications Psychotherapeutic phenothiazine. Antipsychotic.<br>References Schafer, et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Kaye, J., et al.: Br. J. Clin. Pharmacol., 56, 569 (2003), Tschoner, A., et al.: Pharmacopsychiatry, 42, 29 (2009),<br></p>Fórmula:C21H23N3OSCor e Forma:Light Yellow To YellowPeso molecular:365.49Tert-Butyl 2-(pyridin-4-yl)acetate
CAS:Pureza:95.0%Cor e Forma:LiquidPeso molecular:193.24600219726562Ref: 10-F335907
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarAR-C133913XX
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications AR-C133913XX is an metabolte of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)<br></p>Fórmula:C14H22N6O4SCor e Forma:NeatPeso molecular:370.43Nortilidine-d3 Hydrochloride
CAS:Produto ControladoFórmula:C162H3H18NO2·ClHCor e Forma:NeatPeso molecular:298.823-Aminopiperidine-2,6-dione Hydrochloride
CAS:Produto Controlado<p>Applications 3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.<br>References Kronke, J., et al.: Nature 523, 183 (2015); Liu C., et al.: Faming Zhuanli Shenqing CN 105348257 A 20160224 (2016); Rao, R., et al. : PCT Int. Appl. WO 2016024286 A2 20160218 (2016)<br></p>Fórmula:C5H8N2O2·ClHCor e Forma:Off-WhitePeso molecular:164.5904-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride
CAS:Produto Controlado<p>Impurity Paroxetine EP Impurity G<br>Applications 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride (Paroxetine EP Impurity G) is the active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (M325910), N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gerlach, M., et al.: Eur. J. Pharmacol., 208, 273 (1991), Tipton, K., et al.: J. Neurochem., 61, 1191 (1993), Wimalasena, D., et al.: J. Biol. Chem., 279, 15298 (2004),<br></p>Fórmula:C12H14FN·ClHCor e Forma:Light YellowPeso molecular:227.711-(6,7-Dimethoxyphthalazin-1-yl)piperidin-4-yl ethylcarbamate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:360.41400146484375Omeprazole-d3 Sulfide
CAS:Produto ControladoFórmula:C172H3H16N3O2SCor e Forma:NeatPeso molecular:332.44Ref: 10-F200680
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarent-Levobunolol Hydrochloride (R-Bunolol Hydrochloride)
CAS:Produto Controlado<p>Applications A non-selective ß-adrenoceptor antagonist used as an anticonvulsant. The enantiomer of Levobunolol (L335000).<br>References Kaplan, H.R., et al.: Eur. J. Pharm., 16, 237 (1971), DiCarlo,F.J., et al.: Clin. Pharm. Ther., 22, 858 (1977)<br></p>Fórmula:C17H25NO3·ClHCor e Forma:NeatPeso molecular:327.85NAP 226-90
CAS:<p>Impurity Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C<br>Applications NAP 226-90 (Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C) is a S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Br. Med. J., 318, 633 (1999), Jann, M., et al.: Clin. Pharmacokinet., 41, 719 (2002), Frankfort, S., et al.: Int. J. Clin. Pract., 60, 646 (2006),<br></p>Fórmula:C10H15NOCor e Forma:WhitePeso molecular:165.234-(Trifluoromethyl)aniline
CAS:Produto Controlado<p>Impurity Leflunomide EP Impurity A; Leflunomide USP Related Compound A<br>Applications 4-(Trifluoromethyl)aniline (Leflunomide EP Impurity A; Leflunomide USP Related Compound A) is a 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Weber, W., et al.: Pharmacol. Rev., 37, 25 (1985), Hein, D., et al.: Carcinogenesis, 14, 1633 (1993), Payton, M., et al.: Microbiology, 147, 1137 (2001), Mushtaq, A., et al.: J. Biol. Chem., 277, 12175 (2002),<br></p>Fórmula:C7H6F3NCor e Forma:NeatPeso molecular:161.12Ambrisentan Methyl Ester
CAS:Produto Controlado<p>Applications (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)-oxy)-3-methoxy-3,3-diphenylpropanoate is a useful intermediate in the preparation of Ambrisentan. Ambrisentan is an Antihypertensive. Ambrisentan Impurity (A575860).<br>References Peng, X., et al.: J. Org. Chem., 77, 701 (2012), Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003)<br></p>Fórmula:C23H24N2O4Cor e Forma:Off-WhitePeso molecular:392.45Intedanib
CAS:Produto Controlado<p>Applications It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Fórmula:C31H33N5O4Cor e Forma:NeatPeso molecular:539.624-(3,5-dimethyl-1H-pyrazol-1-yl)benzenesulfonyl chloride
CAS:Cor e Forma:SolidPeso molecular:270.73001098632813-Methyl-1-{4-[4-(propan-2-yl)benzenesulfonyl]phenyl}-1H-pyrazol-5-amine
CAS:Pureza:97%Peso molecular:355.4599914550781Methylchloroisothiazolinone/Methylisothiazolinone Mixture
CAS:<p>Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.</p>Fórmula:C8H9ClN2O2S2Cor e Forma:SolidPeso molecular:264.75Bunitrolol
CAS:<p>Applications Bunitrolol is a beta adrenoceptor antagonist that is used as an antihypertensive and antianginal agent.<br>References Narimatsu, S., et al.: Chirality, 11, 1 (1999); Tsuchihashi, H., et al.: Jpn. J. Pharmacol., 45, 349 (1987)<br></p>Fórmula:C14H20N2O2Cor e Forma:Colourless To Light YellowPeso molecular:248.32a-Phenyl-a-ethylacetamide
CAS:Produto Controlado<p>Impurity Primidone USP Related Compound C<br>Applications α-Phenyl-α-ethylacetamide acts as a hypolipaemic agent used in the treatment of high levels of cholesterol.<br>References Marrero-Ponce, Y. et al.: Bioorg. Med. Chem., 13, 2881 (2005); Gohil, V. et al: Nat. Biotech., 28, 249 (2010);<br></p>Fórmula:C10H13NOCor e Forma:NeatPeso molecular:163.22Difenoconazole
CAS:<p>Applications Pestanal is an fungicide that exhibits a broad spectrum of activities against a wide variety of fungi including members of the Aschomycetes, Basidomycetes and Deuteromycetes families.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pinto, A., et al.: Sci. Tot. Environ., 435, 402 (2012); Bakirci, G.T., et al.: Food. Chem., 135, 1901 (2012); Sharma, A.K., et al.: Pestology., 36, 47 (2012);<br></p>Fórmula:C19H17Cl2N3O3Cor e Forma:ColourlessPeso molecular:406.26N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide
CAS:Produto Controlado<p>Impurity Bicalutamide Oxirane Impurity / Bicalutamide Epoxide Impurity<br>Applications N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.<br>References Nandu Baban, B., et al.: Synthetic Communications, 39, 1516 (2009);<br></p>Fórmula:C12H9F3N2O2Cor e Forma:NeatPeso molecular:270.211H-Benzimidazole-4-methyl-2-propyl-6-carboxylic Acid
CAS:Produto ControladoFórmula:C12H14N2O2Cor e Forma:NeatPeso molecular:218.254-Chloro Bupropion Fumarate
CAS:Produto Controlado<p>Applications A 4-chloro substituted analogue of Bupropion (B689625) used in the preparation of compounds for indirect dopamine agonist pharmacotherapy for treating cocaine, methamphetamine, nicotine, and other drugs of abuse addiction.<br>References Carroll, F.I. et al.: J. Med. Chem., 52, 6768 (2009);<br></p>Fórmula:C13H17Cl2NO·C4H4O4Cor e Forma:NeatPeso molecular:390.265-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine
CAS:Produto Controlado<p>Applications 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, is a Anaplastic lymphoma kinase (ALK) inhibitor.<br>References Marsilje, T. H., et al.: J. Med. Chem., 56, 5675 (2013);<br></p>Fórmula:C28H36ClN5O3SCor e Forma:NeatPeso molecular:558.14Defluoro-6-chloro Norfloxacin Hydrochloride
CAS:Fórmula:C16H18ClN3O3·HClCor e Forma:Off-WhitePeso molecular:372.254-AMINO-3-CHLOROPICOLINIC ACID METHYL ESTER
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:186.600006103515623-Amino-5-(4-phenoxyphenyl)thiophene-2-carboxylic acid methyl ester
CAS:Cor e Forma:SolidPeso molecular:325.38000488281252-[5-amino-3-(2-thienyl)-1H-pyrazol-1-yl]-6-methylpyrimidin-4(3H)-one
CAS:Pureza:95.0%Peso molecular:273.309997558593754-[[4-Fluoro-3-(1-piperazinylcarbonyl)phenyl]methyl]-1(2H)-phthalazinone
CAS:Produto ControladoFórmula:C20H19FN4O2Cor e Forma:Off-WhitePeso molecular:366.39Ref: 10-F625925
1gA consultar5gA consultar10gA consultar100mgA consultar250mgA consultar500mgA consultarClioquinol
CAS:Produto Controlado<p>Applications Clioquinol is used as an antiparasitic compound, known to induce apoptosis in leukemia and myeloma cells.<br>References Cao, B. et al.: J. Biol. Chem., 288, 34181 (2013); Chen, Z. et al.: Eur J. Med. Chem., 68, 454 (2013);<br></p>Fórmula:C9H5ClINOCor e Forma:NeatPeso molecular:305.504-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is used in the preparation of (pyridinyl)-N-[(triazolyl)phenyl]pyrimidinamine derivatives and (pyridinyl)-N-[oxadiazolyl)phenyl]pyrimidinamine derivatives, and can be used in the detection of their activity as antileukemia agents (neoplastic stem cell leukemia). 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is also a Nilotinib (N465300) intermediate, which might be useful in treatment of chronic myelogenous leukemia.<br>References Li, Y., et al.: Bioorg. Med. Chem. Lett., 26, 1419-1427 (2016)<br></p>Fórmula:C17H14N4O2Cor e Forma:NeatPeso molecular:306.32(R)-Pramipexole Dihydrochloride
CAS:Produto Controlado<p>Impurity Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D<br>Applications (R)-Pramipexole Dihydrochloride (Pramipexole EP Impurity D; Pramipexole BP Impurity D; Pramipexole USP Related Compound D) is the opposite enantiomer of Pramipexole (P700755), a dopamine-D2-receptor agonist. Dexpramipexole is a low-molecular-weight, water-soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics.<br>References Mierau, J., et al.: J. Med. Chem., 30, 494 (1987), Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)<br></p>Fórmula:C10H17N3S·2ClHCor e Forma:NeatPeso molecular:284.25Desmethylene Tadalafil
CAS:<p>Stability Hygroscopic<br>Applications Tadalafil. A phosphodiesterase 5 inhibitor.<br></p>Fórmula:C21H19N3O4Cor e Forma:Off White PowderPeso molecular:377.395-Methylisoxazole-4-carboxylic Acid
CAS:Produto ControladoFórmula:C5H5NO3Cor e Forma:NeatPeso molecular:127.10N-[1-(1H-1,2,3-Benzotriazol-1-yl)-3-phenylpropyl]pyridine-4-carboxamide
Peso molecular:357.4169921875S-Mirtazapine
CAS:Produto Controlado<p>Applications S-Mirtazapine is an enantiomer of Mirtazapine (M365000); an antidepressant. R-Mirtazapine showed antinociceptive effects in acute thermal nociception, whereas S-Mirtazapine showed pronociceptive effects.<br>References Muth-Selbach, Uta., et al.: Brain Res. Bull., 79(1), 63-68 (2009); Smith, Donald F., et al.: Psychopharmacology, 200(2), 273-279 (2008); Freynhagen, Rainer., et al.: Brain Res. Bull., 69(2), 168-173 (2006)<br></p>Fórmula:C17H19N3Cor e Forma:NeatPeso molecular:265.35Lenalidomide Lactosamine Adduct
Produto Controlado<p>Stability Hygroscopic<br>Applications Lenalidomide Lactosamine Adduct is a derivative of Lenalidomide (L328000), an oral immunomodulatory agent for the management of myelodysplastic syndromes.<br>References Bartlett, J.B., et al.: Nature Rev., 4, 314 (2004); Mitsiades, C.S., et al.: Curr. Opin. Invest. Drugs, 5, 635 (2004); List, A., et al.: N. Engl. J. Med., 352, 549 (2005)<br></p>Fórmula:C25H33N3O13Cor e Forma:NeatPeso molecular:583.542-(9-(Pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)acetonitrile
CAS:Pureza:97%Cor e Forma:SolidPeso molecular:256.34899902343752-Ethyl-2-phenylmalonamide-d5
CAS:Produto Controlado<p>Applications A labelled metabolite of Primidone.<br>References Holler, M., et al.: Biochem. Pharmacol., 33, 1753 (1984), Lafont, O., et al.: Eur. J. Med. Chem., 25, 61 (1990), Fisher, J., et al.: Pharmacol. Res., 26, 207 (1992), Florence, A., et al.: Pharmacol. Res., 14, 259 (1997), El-Masri, H., et al.: Drug Metab. Dispos., 26, 585 (1998),<br></p>Fórmula:C11H9D5N2O2Cor e Forma:NeatPeso molecular:211.274-((5,6-Diphenylpyrazin-2-yl)(isopropyl)amino)butan-1-ol
CAS:Pureza:98%Peso molecular:361.489013671875Levofloxacin-d3
CAS:Produto Controlado<p>Applications Levofloxacin-d3, is the labeled analogue of Levofloxacin (L360000), an antibiotic used against gram-negative organisms.<br>References Kato, M., et al.: Arzneim.-Forsch., 42, 365 (1992), North, D.S., et al.: Pharmacotherapy, 18, 915 (1998), Hwang, D.G., et al.: Br. J. Ophthalmol., 87, 1004 (2003),<br></p>Fórmula:C18H17D3FN3O4Cor e Forma:NeatPeso molecular:364.39Ketoconazole
CAS:Produto Controlado<p>Applications Inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor. Inhibitor of exosome secretion.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986); Scientific Reports 8: 8161 (2018)<br></p>Fórmula:C26H28Cl2N4O4Cor e Forma:NeatPeso molecular:531.43Etoricoxib-d6
CAS:Produto Controlado<p>Applications Etoricoxib-d6 is the labelled analog of Etoricoxib (E934100), a specific inhibitor of COX-2 .<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002), Chenevard, R., et al.: Circulation, 107, 405 (2003)<br></p>Fórmula:C18H9D6ClN2O2SCor e Forma:NeatPeso molecular:364.88Irbesartan-d7 2,2,2-Trifluoroacetate Salt
CAS:Produto ControladoFórmula:C25D7H21N6O·C2HF3O2Cor e Forma:NeatPeso molecular:549.60Omeprazole Sulfide
CAS:Produto ControladoFórmula:C17H19N3O2SCor e Forma:White To Light BrownPeso molecular:329.428-ethyl-4-(thiophene-2-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:324.39999389648443-(1,3-benzodioxol-5-yl)-1-methyl-1{H}-pyrazole-5-carboxylic acid
CAS:Pureza:95.0%Peso molecular:246.22200012207032-(2,5-dimethyl-1H-indol-3-yl)-N-(thiophen-2-ylmethyl)ethan-1-amine hydrochloride
CAS:Pureza:95.0%Peso molecular:320.8800048828125Benzidine
CAS:Produto Controlado<p>Applications Potentially mutagenic compound. Dyes and metabolites, Environmental Testing.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dairou, J., et al.: Toxicol. App. Pharmacol., 236, 366 (2009), Toropov, A., et al.: Chem. Biol. Drug Design, 73, 482 (2009),<br></p>Fórmula:C12H12N2Pureza:95%Cor e Forma:Tan Or Dark Grey To BlackPeso molecular:184.247-Nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine
CAS:<p>7-Nitroso-3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine is a useful research chemical compound.<br></p>Fórmula:C6H6F3N5OCor e Forma:White To Off-WhitePeso molecular:221.14Fingolimod-d4 Hydrochloride
CAS:Produto Controlado<p>Applications A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).<br>References Brinkmann, V., et al.: Transplantation, 72, 764 (2001), Brinkmann, et al.: J. Biol. Chem., 277, 24, 21453 (2002), Mtaloubian, M., et al.: Nature, 427, 355 (2004),<br></p>Fórmula:C19H30D4ClNO2Cor e Forma:NeatPeso molecular:347.96
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