APIs para pesquisa e impurezas
Os Ingredientes Farmacêuticos Ativos (APIs) são as substâncias nos medicamentos responsáveis por seus efeitos terapêuticos. Nesta seção, você encontrará uma ampla variedade de APIs destinados a uso em pesquisa. Esses compostos são essenciais para o desenvolvimento, teste e validação de novas formulações farmacêuticas. Na CymitQuimica, oferecemos APIs de alta qualidade para apoiar a pesquisa em descoberta e desenvolvimento de medicamentos.
Subcategorias de "APIs para pesquisa e impurezas"
- Aminoácidos e Derivados(12.441 produtos)
- Antraquinonas e Derivados(407 produtos)
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- Derivados das Benzodiazepinas(335 produtos)
- Carboidratos e Glicoconjugados(5.388 produtos)
- Ésteres e Derivados(42.307 produtos)
- Ácidos Graxos e Derivados Lipídicos(32.488 produtos)
- Flavonoides e Polifenóis(17.101 produtos)
- Radicais Livres e Agentes Oxidantes/Redutores(214 produtos)
- Cetonas e Derivados(2.692 produtos)
- Antibióticos Naturais e Semissintéticos(6.411 produtos)
- Nitrilas e Derivados Ciano(3.070 produtos)
- Nitrosaminas e Derivados(55 produtos)
- Nucleosídeos e Nucleotídeos(3.492 produtos)
- Fosfatos e Fosfonatos Orgânicos(1.205 produtos)
- Sulfonatos e Sulfatos Orgânicos(10.452 produtos)
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- Outros(6.340 produtos)
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- Polímeros e Derivados(100 produtos)
- Derivados de Purinas e Pirimidinas(8.975 produtos)
- Derivados de Quinazolina e Quinolina(66.221 produtos)
- Quinonas e Derivados(24.379 produtos)
- Sais e Derivados de API(92.967 produtos)
- Esteroides e Derivados(4.987 produtos)
- Sulfonamidas e Derivados(2.607 produtos)
- Terpenoides e Derivados(3.871 produtos)
- Tiazolidinedionas e Tiopiranos(2.755 produtos)
- Compostos β-Adrenérgicos(232 produtos)
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3-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid
CAS:3-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid is a chemical compound that is an impurity standard for HPLC. It is also used as a pharmacopoeia, drug development, and analytical reference standard. The CAS number for this compound is 66364-71-4. This compound has been shown to be metabolized by microsomal oxidation, glucuronidation, or sulfation pathways in humans. 3-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid can also be found in natural sources such as plants and animals.Fórmula:C18H14N4O5SPureza:Min. 95%Cor e Forma:PowderPeso molecular:398.39 g/molBis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide
CAS:Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide is a disulfide derivative of famotidine. It has been used as an analytical reagent for the determination of impurities in famotidine and other related compounds. Bis-[[2-[(diaminomethylene)amino]thiazol-4-yl]methyl]disulfide is soluble in methanol, ethanol and water, but not in acetone. The compound can be prepared by reacting 4-(dimethylamino)-1H-1,2,3-benzothiadiazole with 2-[(diaminomethylene)amino]-4-(N'-methoxycarbonylthio)benzaldehyde and then reductive amination with sodium bisulfite.
Fórmula:C10H14N8S4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:374.54 g/molMethyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate
CAS:Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate is a hydrophobic, colorless liquid with a pungent odor. It is an additive that can be used in the manufacturing of epoxy resins to increase their light resistance and corrosion resistance. This product also has immunity properties and may be used as an immunotherapy agent for the treatment of viral infections. Methyl-3-[5-(2-methoxycarbonylethyl)pyrazin-2-yl]propionate has been shown to activate immune cells and promote cell immunity by increasing the production of cytokines. It may also be used as a virus transfer agent for the prevention of viral infection.Fórmula:C12H16N2O4Pureza:Min. 95%Cor e Forma:White to off-white powder.Peso molecular:252.27 g/molN-(((5R)-3-(3-Fluoro-4- (4-morpholinyl)phenyl)-2-oxo- 5-oxazolidinyl)methyl) acetamide
CAS:N-(((5R)-3-(3-Fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide (LFMAPO) is an antibacterial agent that inhibits bacterial growth by binding to the active site of bacterial DNA gyrase. LFMAPO has a molecular weight of 552.2 Da and a log P value of 2.6. It was synthesized from acetamide, 3-fluoroaniline, and 4-(4-morpholinyl)benzaldehyde in 60% yield using techniques such as millimolar stoichiometry, electrophoresis method, binding constants, and molecular modeling study. The drug also has chiral properties with two stereocenters at carbons C1 and C5 that have been shown to be important for the activity of this compound against Gram positive bacteria.
Fórmula:C16H20FN3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:337.35 g/molHomo sildenafil
CAS:Analogue of sildenafilFórmula:C23H32N6O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:488.6 g/mol(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate
CAS:(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate is a white to off-white crystalline powder that is soluble in methanol and slightly soluble in water. It can be used as an impurity standard for the API drug product, research and development and metabolism studies. The CAS number for this compound is 2200280-99-3. This compound has a purity of 99% or greater with an analytical purity of 99.9%. This compound has been shown to have a melting point of about 237°C and a density of 1.06 g/cm3. This compound is insoluble in ether and acetone.Fórmula:C21H26N2O7Pureza:Min. 95%Cor e Forma:Light (Or Pale) Yellow To Yellow SolidPeso molecular:418.44 g/molOlsalazine sodium impurity D
CAS:Olsalazine sodium impurity D is a natural substance that is present as an impurity in the drug Olsalazine sodium. It is used as an analytical standard for Olsalazine sodium and its metabolites, which are involved in drug development. The purity of this substance can be customized by our research and development team. This product has CAS number 93964-55-7 and is available at a reasonable price.
Fórmula:C14H9ClN2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:320.68 g/mol(S)-6-(Ethyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride
CAS:(S)-6-(Ethyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride is a synthetic compound that has been designed for use as an impurity standard in the validation of analytical methods. It is a custom synthesis product and is not commercially available. It is a white crystalline solid with a melting point of 170°C and its molecular formula is C14H12N2O3S. (S)-6-(Ethyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol hydrochloride has been shown to have no biological activity in rats.Fórmula:C18H24ClNOSPureza:Min. 95%Peso molecular:337.9 g/molPantoprazole N-oxide sodium
CAS:Pantoprazole N-oxide sodium is a custom synthesis drug product that is being developed as an impurity standard in the synthesis of Pantoprazole. The compound is also used as a pharmacopoeia analytical standard and a HPLC standard.Fórmula:C16H15F2N3O5S·NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:422.36 g/molLisinopril EP Impurity E
CAS:Lisinopril EP Impurity E is an impurity of lisinopril, which is a prescription drug used to treat high blood pressure. This impurity was found in a preparative high performance liquid chromatography (HPLC) and mass spectroscopy analysis of the drug. The molecular weight of Lisinopril EP Impurity E was determined to be 317.2 amu, which corresponds to the molecular formula C7H13NO2. The FT-IR spectrum showed that this impurity has an ammonium group at 1859 cm-1 and butanoic acid at 1647 cm-1.Fórmula:C21H31N3O5Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:405.49 g/molTyrosol glucuronide
CAS:Tyrosol is a phenolic compound found in olive oil and other plant sources. It has been shown to have antioxidant, anti-inflammatory, and anti-cancer activities. Tyrosol glucuronide is the main form of tyrosol found in urine samples. The absorption process of tyrosols is due to their uptake by the liver cells, where they are converted into fatty acids and then conjugated with glucuronic acid. Tyrosols are also metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Studies have shown that tyrosols can help lower blood pressure and improve insulin resistance in women.Fórmula:C14H18O8Pureza:Min. 95%Cor e Forma:PowderPeso molecular:314.29 g/mol(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:(1S)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a drug used to treat depression. It is an antidepressant drug that inhibits the reuptake of serotonin and norepinephrine in the brain by blocking their transport into the nerve cells. The drug acts as a weak inhibitor of monoamine oxidase (MAO). It also has an effect on bladder function. This compound is synthesized from 1-phenyl-2,5-dihydrothiazole by way of a sequence of reactions that includes the formation of an amine salt via reaction with phosphorus pentoxide and chloroacetic acid followed by conversion to the chloride with thionyl chloride.Fórmula:C15H15NPureza:Min. 95%Cor e Forma:White PowderPeso molecular:209.29 g/molα-Methyl-1,3-benzodioxole-5-propanamine
CAS:Produto Controladoα-Methyl-1,3-benzodioxole-5-propanamine (AMEB) is a chemical compound that minimizes the reaction products in industrial reactions. It has been used as an absorption agent and crosslinking agent in bioconjugate chemistry. The hydroxyl group on AMEB can be removed by hydrolysis to yield α-methyl-1,3-benzodioxole, which can then be converted to the amino acid methionine. AMEB has also been shown to have locomotor activity and to increase the synthesis of hyaluronic acid, which is important for maintaining joint health.
Fórmula:C11H15NO2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:193.24 g/molLansoprazole N-oxide
CAS:Lansoprazole N-oxide is a prodrug that is converted to lansoprazole sulfone in vivo. Lansoprazole N-oxide is used as a diluent in chromatographic experiments. It has been shown to be more sensitive than the parent compound, lansoprazole, for the diagnosis of reflux oesophagitis. Lansoprazole N-oxide also has a validation wavelength of 240 nm and can be detected by liquid chromatography. The active form of lansoprazole, lansoprazole sulfone, can be detected by gas chromatography mass spectrometry (GCMS).Fórmula:C16H14F3N3O3SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:385.36 g/mol2-Amino-5,6-dichloro-3(4H)-quinazolineacetic acid methyl ester monohydrobromide
CAS:2-Amino-5,6-dichloro-3(4H)-quinazolineacetic acid methyl ester monohydrobromide is a metabolite of the drug product 2-amino-5,6-dichloroquinazoline acetic acid methyl ester. It is a synthetic compound that is used as an impurity standard for pharmaceuticals and other products. This chemical can be custom synthesized to meet your needs. It has been shown to have high purity and can be used in research and development or as a pharmacopoeia reference material.Fórmula:C11H12Cl2BrN3O2Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:369.04 g/molAcetaminophen acetate
CAS:Acetaminophen acetate is a cholinergic amine that binds to the active site of the enzyme acetylcholine esterase, preventing it from breaking down acetylcholine. Acetaminophen is used as a pain reliever and antipyretic agent. It is also used for its anti-inflammatory effects in the treatment of rheumatoid arthritis and other inflammatory conditions. Acetaminophen has been shown to have anticancer properties, which may be due to its ability to bind to cancer cells, inhibit their growth, and induce apoptosis. Acetaminophen acetate is also an acylation reaction product that can be isolated by liquid chromatography in phase with fluorescence properties.Fórmula:C10H11NO3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:193.2 g/molRaloxifene N-oxide
CAS:Raloxifene N-oxide is a synthetic drug product that is used in the treatment of osteoporosis. It belongs to the family of selective estrogen receptor modulators (SERM). Raloxifene N-oxide has been shown to inhibit bone resorption and reduce the risk of vertebral fractures. It also has anti-estrogenic effects, which have been shown to be beneficial for prostate cancer patients who are receiving androgen deprivation therapy. Raloxifene N-oxide is an impurity in the synthesis of raloxifene, which is a drug product with CAS number 195454-31-0. The purity of this compound should be at least 99%.Fórmula:C28H27NO5SPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:489.58 g/molDesmethyl tacrolimus
CAS:Tacrolimus is a macrolide antibiotic that binds to the calcineurin receptor and inhibits the production of cytokines. It is used to treat certain types of autoimmunity and hyperproliferation in patients with cancer, organ transplant recipients, and those who have undergone radiation therapy. The drug is available in two forms: tacrolimus (the natural form) and desmethyl tacrolimus (a metabolite). Desmethyl tacrolimus is produced by microbial transformation, which converts the natural form into a more water-soluble derivative. This conversion can be prevented by adding additives such as proton pump inhibitors or pde5 inhibitors. Symptoms of tacrolimus include hyperglycemia, hyperlipidemia, gastrointestinal disturbances, headache, fever, skin rash, diarrhea, and anemia. Tacrolimus has been shown to inhibit the activity of fk506-binding proteins in vitro and in vivo through competitive inhibition.Fórmula:C43H67NO12Pureza:Min. 90 Area-%Cor e Forma:White PowderPeso molecular:789.99 g/molBis-[[2-aminoethyl]thio]methane
CAS:Bis-[[2-aminoethyl]thio]methane is a custom synthesis, drug product, niche, Metabolite, Drug development, Natural, pharmacopoeia and API impurity. This chemical is CAS No. 22907-27-3 and has the molecular weight of 249.00 g/mol. It can be synthesized in the laboratory using the following methods: HPLC standard, Research and Development and Impurity standard. The chemical is an analytical standard with a purity of 99%. This chemical can be used as analytical reagent or in research and development of drugs.Fórmula:C5H14N2S2Pureza:Min. 95%Cor e Forma:Clear LiquidPeso molecular:166.31 g/mol
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