APIs para pesquisa e impurezas

Ethyl 3-aminopyrazole-4-carboxylate is an anticancer drug that inhibits the growth of cancer cells by inhibiting protein synthesis. It has been shown to inhibit the activity of dpp-iv and pde5, which are enzymes involved in cellular proliferation. Ethyl 3-aminopyrazole-4-carboxylate has also been shown to have antiinflammatory properties, which may be due to inhibition of prostaglandin synthesis.
Ethyl 3-aminopyrazole-4-carboxylate is a multinuclear compound that reacts with nitrogen atoms from the pyrazoles to form a stable molecule. Dimethylformamide is used as a solvent for this reaction. The synthesis of ethyl 3-aminopyrazole-4-carboxylate starts with acetylation, which converts the carboxylic acid group into an acetic acid group. The acetic acid group reacts with ammonia and hydrogen cyan

2-Carboxybenzoyl amlodipine is a metabolite of the antihypertensive drug amlodipine. It is a white crystalline solid that is soluble in water. 2-Carboxybenzoyl amlodipine can be used as an impurity standard for HPLC analyses, and as an analytical standard for the determination of amlodipine in human plasma.

Cimetidine is a histamine-2 receptor antagonist that inhibits gastric acid secretion and reduces the activity of stomach enzymes. It is used to treat peptic ulcers, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. Cimetidine has been shown to inhibit the activity of drug-metabolizing enzymes such as cytochrome P450. Cimetidine also inhibits the transport protein P-glycoprotein (P-gp), which leads to increased concentrations of some drugs in the blood and tissues. This inhibition may lead to an increase in cardiac effects with certain drugs, such as x-ray diffraction data with taxol or h1 antagonists.

All-trans-retinol-d5 is a supplement that is used to protect the brain from oxidative damage and to help maintain healthy skin. It is an antioxidant that prevents free radicals from damaging cells and helps maintain the structural integrity of cell membranes. All-trans-retinol-d5 can be found in high concentrations in animal tissues, such as liver, lung, kidney, heart, brain, and eye. It can also be found in human urine. The presence of all-trans-retinol-d5 in urine has been correlated with neuroprotective effects. Retinol levels have been shown to be higher in children who are less obese than those who are obese or overweight. All-trans retinol has been shown to inhibit cancer cell proliferation and induce apoptosis by inhibiting protein synthesis at the level of transcription.

2-Phenylbutyric acid is a product of the oxidation of phenylacetic acid by flavus. 2-Phenylbutyric acid is an inhibitor of contactor reactions that use α1-acid glycoprotein as a chromatographic support. It has been shown to inhibit the reaction mechanism of extractants (e.g., butamirate citrate) with enantiomeric compounds (e.g., creatine). It also inhibits subclinical mastitis in cows and fatty acid synthesis, leading to decreased cholesterol synthesis in humans.

2-[[3-(Trifluoromethyl)phenyl]amino] benzoic acid 2-hydroxyethyl ester is a metabolite of the drug desloratadine. It is used as an impurity standard in HPLC and as a metabolite to study metabolism.