CAS 101477-54-7: Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2)
Description:Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2) is a chemical compound characterized by its piperazine core, which is a six-membered heterocyclic structure containing two nitrogen atoms. This compound features a bis(4-fluorophenyl)methyl group and a 2,3,4-trimethoxyphenylmethyl substituent, contributing to its complex structure and potential biological activity. The presence of fluorine atoms typically enhances the lipophilicity and metabolic stability of the compound. As a hydrochloride salt, it is likely to be more soluble in water compared to its free base form, which can facilitate its use in pharmaceutical applications. The trimethoxyphenyl group may impart additional pharmacological properties, making this compound of interest in medicinal chemistry. Its specific interactions and effects would depend on its molecular conformation and the presence of functional groups, which can influence its binding affinity to biological targets. Overall, this compound exemplifies the intricate design often found in drug development, aiming for enhanced efficacy and selectivity.
Formula:C27H30F2N2O3·2ClH
InChI:InChI=1S/C27H30F2N2O3.2ClH/c1-32-24-13-8-21(26(33-2)27(24)34-3)18-30-14-16-31(17-15-30)25(19-4-9-22(28)10-5-19)20-6-11-23(29)12-7-20;;/h4-13,25H,14-18H2,1-3H3;2*1H
InChI key:InChIKey=LOGVKVSFYBBUAJ-UHFFFAOYSA-N
SMILES:Cl.FC1=CC=C(C=C1)C(C2=CC=C(F)C=C2)N3CCN(CC4=CC=C(OC)C(OC)=C4OC)CC3
- Synonyms:
- 1-[Bis(4-Fluorophenyl)Methyl]-4-(2,3,4-Trimethoxybenzyl)Piperazine Dihydrochloride
- Kb 2796
- Lomerizine dihydrochloride
- Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-, dihydrochloride
- Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]-, hydrochloride (1:2)
- Lomerizine hydrochloride