CAS 10148-81-9

γ-Glutamylglutamine

Description:

γ-Glutamylglutamine, also known as a dipeptide, is a compound formed from the amino acids glutamic acid and glutamine. It is characterized by the presence of a γ-glutamyl group, which indicates that the glutamic acid is in its gamma form, linking to the nitrogen of the glutamine. This structure contributes to its unique biochemical properties, including its role in protein synthesis and metabolism. γ-Glutamylglutamine is soluble in water, which facilitates its biological functions, particularly in cellular processes and signaling pathways. It is often studied for its potential roles in nutrition and health, particularly in relation to amino acid transport and cellular stress responses. The compound may also exhibit antioxidant properties, contributing to its significance in various physiological contexts. As a dipeptide, it can be involved in various metabolic pathways and may have implications in clinical nutrition and therapeutic applications. Its CAS number, 10148-81-9, is a unique identifier that aids in the cataloging and study of this specific chemical substance.

Formula: C₁₀H₁₇N₃O₆

InChI: InChI=1S/C10H17N3O6/c11-5(9(16)17)1-4-8(15)13-6(10(18)19)2-3-7(12)14/h5-6H,1-4,11H2,(H2,12,14)(H,13,15)(H,16,17)(H,18,19)/t5-,6-/m0/s1

InChI key: InChIKey=JBFYFLXEJFQWMU-WDSKDSINSA-N

SMILES: [C@H](NC(CC[C@@H](C(O)=O)N)=O)(CCC(N)=O)C(O)=O

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Glutamine, <smallcap>L</span>-γ-glutamyl-
• <span class="text-smallcaps">L</smallcap>-Glutamine, N²-<smallcap>L</span>-γ-glutamyl-
• <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-<smallcap>L</span>-glutamine
• Glutamine, N²-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-, <smallcap>L</span>-
• Glutamine, N²-<span class="text-smallcaps">L</span>-γ-glutamyl-
• H-.gamma.-Glu-Gln-OH
• γ-<span class="text-smallcaps">L</smallcap>-Glutamyl-<smallcap>L</span>-glutamine
• γ-Glu-Gln
• γ-Glutamylglutamine
• L-γ-Glutamyl-L-glutamine
• Glutamine, N2-L-γ-glutamyl-, L-
• L-Glutamine, L-γ-glutamyl-
• L-Glutamine, N2-L-γ-glutamyl-

N5-((S)-4-Amino-1-carboxy-4-oxobutyl)-L-glutamine

CAS: 10148-81-9

N5-((S)-4-Amino-1-carboxy-4-oxobutyl)-L-glutamine

Formula: C₁₀H₁₇N₃O₆

Purity: 98%

Molecular weight: 275.26

Ref: 54-OR1059455

L-Glutamine, L-γ-glutamyl-

CAS: 10148-81-9

Formula: C₁₀H₁₇N₃O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 275.2585

Ref: IN-DA0004L3

H-γ-Glu-Gln-OH

CAS: 10148-81-9

H-γ-Glu-Gln-OH is a hydrophilic peptide linker. It enhances drug solubility, biocompatibility, and tumor-targeting efficiency as a carrier, utilized in the research of self-assembled nanoparticles and anti-tumor drug delivery systems.

Formula: C₁₀H₁₇N₃O₆

Purity: 99.84%

Color and Shape: White Solid

Molecular weight: 275.26

Ref: TM-T78465

H-γ-Glu-Gln-OH

CAS: 10148-81-9

N5-((S)-4-Amino-1-carboxy-4-oxobutyl)-L-glutamine

Formula: C₁₀H₁₇N₃O₆

Purity: 98%

Molecular weight: 275.26

Ref: IN-DG133381

H-Glu(Gln-OH)-OH

CAS: 10148-81-9

Glutamate is a nonessential amino acid that is an important neurotransmitter in the central nervous system. It is found in many foods and can be synthesized by the body from other amino acids. Glutamate is also an excitatory neurotransmitter that binds to glutamate receptors, causing depolarization of the postsynaptic cell. This leads to increased intracellular calcium levels and eventually to neuronal death. Glutamate can be taken up by cells through both facilitated diffusion and active transport and converted into glutamine by glutaminase. The uptake of glutamate into cells may have clinical relevance in diseases such as hepatic steatosis, schizophrenia, or Alzheimer's disease.
Glu(Gln-OH)-OH (HGG) is a synthetic compound that has been shown to inhibit enzymes involved in the shikimate pathway, which converts chorismate into aromatic amino acids such as phenylalanine, tyrosine, and tryptophan. HGG has been

Formula: C₁₀H₁₇N₃O₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 275.26 g/mol

Ref: 3D-FG108031

H-γ-Glu-Gln-OH

CAS: 10148-81-9

Formula: C₁₀H₁₇N₃O₆

Purity: 98%

Molecular weight: 275.112

Ref: 10-F492882

H-γ-GLU-GLN-OH

Controlled Product

CAS: 10148-81-9

Formula: C₁₀H₁₇N₃O₆

Color and Shape: Neat

Molecular weight: 275.259

Ref: TR-G245115

H-Glu(Gln-OH)-OH

CAS: 10148-81-9

γ-Glu-Gln and further kokumi-active γ-glutamyl dipeptides have been isolated from mature Gouda cheese. These branched dipeptides are responsible for the complex taste of the cheese.

Formula: C₁₀H₁₇N₃O₆

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 275.26

Ref: 01-4001245