CAS 103639-04-9: Ondansetron hydrochloride dihydrate
Description:Ondansetron hydrochloride dihydrate is a medication primarily used as an antiemetic to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. It is a selective serotonin 5-HT3 receptor antagonist, which works by blocking the action of serotonin, a neurotransmitter that can trigger nausea. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for intravenous administration. Its molecular formula includes a hydrochloride salt and two water molecules, indicating its dihydrate form. Ondansetron hydrochloride dihydrate has a relatively high melting point and is stable under normal storage conditions. It is typically administered orally or intravenously, and its pharmacokinetics show a rapid onset of action, with a half-life that allows for effective dosing schedules. Common side effects may include headache, constipation, and dizziness, but it is generally well-tolerated. As with any medication, it is essential to use ondansetron under medical supervision to manage potential interactions and contraindications effectively.
Formula:C18H19N3O·ClH·2H2O
InChI:InChI=1S/C18H19N3O.ClH.2H2O/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;;;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H;2*1H2
InChI key:InChIKey=VRSLTNZJOUZKLX-UHFFFAOYSA-N
SMILES:Cl.O=C1C=2C=3C=CC=CC3N(C2CCC1CN4C=CN=C4C)C.O
- Synonyms:
- (+-)-2,3-Dihydro-9-Methyl-3-((2-Methylimidazol-1-Yl)Methyl)Carbazol-4(1H)-One Monohydrochloride Dihydrate
- 1,2,3,9-Tetrahydro-9-Methyl-3-[(2-Methyl-1H-Imidazol-1-Yl)Methyl]-4H-Carbazol-4-One Hydrochloride Dihydrate
- 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride (1:1)
- 4H-Carbazol-4-One, 1,2,3,9-Tetrahydro-9-Methyl-3-((2-Methyl-1H-Imidazol-1-Yl)Methyl)-, Monohydrochloride, (+-)-, Dihydrate
- 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, monohydrochloride
- 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-, hydrochloride, hydrate (1:1:2)
- 9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one monohydrochloride
- 9-Methyl-3-[(2-Methylimidazol-1-Yl)Methyl]-2,3-Dihydro-1H-Carbazol-4-One Dihydrate Hydrochloride
- 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride (1:1)
- 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride dihydrate
- See more synonyms
- Carbazol-4-One Dihydrate
- Odansetron Hydrochloride Dihydrate
- Ondansetron HCl
- Ondansetron Hcl Dihydrate
- Ondansetron Hydrochloride Hydrate
- Zofran
- Zofran ODT
- Zophren
- Zudan
- Ondansetron hydrochloride dihydrate
