CAS: 1037624-75-1 - BGB 324

Formula: C₃₀H₃₄N₈

InChI: InChI=1S/C30H34N8/c31-29-33-30(32-24-13-10-20-11-14-25(15-12-22(20)18-24)37-16-3-4-17-37)36-38(29)27-19-23-8-5-7-21-6-1-2-9-26(21)28(23)35-34-27/h1-2,6,9-10,13,18-19,25H,3-5,7-8,11-12,14-17H2,(H3,31,32,33,36)/t25-/m0/s1

InChI key: InChIKey=KXMZDGSRSGHMMK-VWLOTQADSA-N

SMILES: N1=NC=2C3=CC=CC=C3CCCC2C=C1N4N=C(N=C4N)NC5=CC=C6C(=C5)CCC(N7CCCC7)CC6

Synonyms:

• BGB 324
• 1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-[(7-(S)-pyrrolidin-1-yl)-6,7,8,9-tetrahydro-5H-benzo[7]annulene-2-yl]-1H-1,2,4-triazole-3,5-diamine
• 1-(6,7-Dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-[(7S)-6,7,8,9-tetrahydro-7-(1-pyrrolidinyl)-5H-benzocyclohepten-2-yl]-1H-1,2,4-triazole-3,5-diamine
• R 428
• 1H-1,2,4-Triazole-3,5-diamine, 1-(6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazin-3-yl)-N3-[(7S)-6,7,8,9-tetrahydro-7-(1-pyrrolidinyl)-5H-benzocyclohepten-2-yl]-

Bemcentinib

CAS: 1037624-75-1

Bemcentinib (R428) is a selective inhibitor of Axl (IC50: 14 nM) and has been investigated …

• Formula: C₃₀H₃₄N₈
• Purity: 97% - 99.8%
• Color and Shape: Solid
• Molecular weight: 506.64

R428

CAS: 1037624-75-1

R428

CAS: 1037624-75-1

R428 is a small-molecule drug that is capable of inhibiting the BCR-ABL kinase and blocking …

• Formula: C₃₀H₃₄N₈
• Purity: Min. 95%
• Molecular weight: 506.64 g/mol

R 428

CAS: 1037624-75-1

Applications R 428 is an AXL tyrosine kinase inhibitor shown to be used as an …

• Formula: C₃₀H₃₄N₈
• Color and Shape: Neat
• Molecular weight: 506.64

R428

CAS: 1037624-75-1

• Formula: C₃₀H₃₄N₈
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 506.6446