CAS 105394-83-0
:Decarboxy Ciprofloxacin
Description:
Decarboxy Ciprofloxacin, with the CAS number 105394-83-0, is a derivative of the fluoroquinolone antibiotic ciprofloxacin. This compound is characterized by the removal of a carboxyl group from the ciprofloxacin structure, which may influence its pharmacological properties. Like its parent compound, Decarboxy Ciprofloxacin exhibits antibacterial activity, primarily targeting gram-negative bacteria by inhibiting bacterial DNA gyrase and topoisomerase IV, essential enzymes for bacterial DNA replication and transcription. The modification in its chemical structure can affect its solubility, stability, and overall bioactivity. Additionally, the compound may have different pharmacokinetic properties compared to ciprofloxacin, potentially impacting its absorption, distribution, metabolism, and excretion in biological systems. Research into its specific applications and efficacy is ongoing, as derivatives of established antibiotics can provide insights into overcoming resistance and enhancing therapeutic options. As with any pharmaceutical compound, safety and efficacy assessments are crucial for its potential use in clinical settings.
Formula:C16H18FN3O
InChI:InChI=1/C16H18FN3O/c17-13-9-12-14(10-15(13)19-7-4-18-5-8-19)20(11-1-2-11)6-3-16(12)21/h3,6,9-11,18H,1-2,4-5,7-8H2
SMILES:C1CC1n1ccc(=O)c2cc(c(cc12)N1CCNCC1)F
Synonyms:- 1-Cyclopropyl-6-fluoro-7-(1-piperazinyl)-4(1H)-quinolinone
- 1-cyclopropyl-6-fluoro-7-piperazin-1-ylquinolin-4(1H)-one
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Found 8 products.
Ciprofloxacin impurity standard
CAS:Ciprofloxacin impurity standardFormula:C17H21ClFN3O4Color and Shape:Light YellowMolecular weight:385.8177Decarboxy Ciprofloxacin
CAS:Formula:C16H18FN3OPurity:98%Color and Shape:SolidMolecular weight:287.33201-Cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-one
CAS:1-Cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-onePurity:98%Molecular weight:287.34g/molCiprofloxacin EP Impurity E
CAS:Formula:C16H18FN3OColor and Shape:White To Off-White SolidMolecular weight:287.341-Cyclopropyl-6-fluoro-7-(piperazin-1-yl)quinolin-4(1H)-one (Decarboxylated Compound)
CAS:Controlled ProductFormula:C16H18FN3OColor and Shape:NeatMolecular weight:287.33Decarboxy Ciprofloxacin
CAS:Controlled Product<p>Impurity Ciprofloxacin Impurity E<br>Applications Ciprofloxacin impurity. Ciprofloxacin Impurity E<br>References Borner, K, et al.: J. Clin. Chem. Clin. Biochem., 24, 325 (1986), Lacroix, P., et al.: J. Pharm. Biomed. Anal., 14, 641 (1996), Barron, D., et al.: Anal. Chim. Acta, 415, 83 (2000,<br></p>Formula:C16H18FN3OColor and Shape:NeatMolecular weight:287.33Decarboxy ciprofloxacin
CAS:<p>Decarboxy ciprofloxacin is a prodrug that is active against bacteria and other microorganisms. It has been shown to have an affinity for the fluoroquinolone binding site on the bacterial ribosome, inhibiting protein synthesis and cell division. Decarboxy ciprofloxacin has been used in animals to treat infections caused by Escherichia coli, Klebsiella pneumoniae, Salmonella enterica, Proteus mirabilis, and Pseudomonas aeruginosa. Decarboxy ciprofloxacin is administered orally in the form of tablets or capsules. The drug binds to metal ions and can be detected with a biosensor that uses an aptamer-coated electrode. This sensor can be used for the detection of both metal ions and fluoroquinolones. <br>Decarboxy ciprofloxacin is also used as a research tool to</p>Formula:C16H18FN3OPurity:Min. 95%Color and Shape:PowderMolecular weight:287.33 g/mol
