CAS 1069-66-5

Sodium valproate

Description:

Sodium valproate, with the CAS number 1069-66-5, is the sodium salt of valproic acid, a compound widely used in the treatment of epilepsy and bipolar disorder. It appears as a white to off-white crystalline powder and is highly soluble in water, which facilitates its administration in various pharmaceutical formulations. The substance acts primarily as an anticonvulsant and mood stabilizer, functioning by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, thereby exerting a calming effect on neuronal activity. Sodium valproate is typically administered orally, and its pharmacokinetics can be influenced by factors such as age, liver function, and concurrent medications. While generally well-tolerated, it may cause side effects, including gastrointestinal disturbances, weight gain, and, in rare cases, hepatotoxicity. Due to its potential teratogenic effects, careful consideration is necessary when prescribing to pregnant individuals. Overall, sodium valproate is a crucial therapeutic agent in managing certain neurological and psychiatric conditions.

Formula: C₈H₁₆O₂·Na

InChI: InChI=1S/C8H16O2.Na/c1-3-5-7(6-4-2)8(9)10;/h7H,3-6H2,1-2H3,(H,9,10);

InChI key: InChIKey=RGZUPIWJTSGERU-UHFFFAOYSA-N

SMILES: C(CCC)(CCC)C(O)=O.[Na]

Synonyms:

• Acediprol
• Convulex
• Depacon
• Depakene
• Depakene R
• Depakene syrup 8
• Depakin
• Depakine chronosphere
• Dipropylacetate sodium
• Encorate
• Epilim
• Kw 6066N
• Micropakine LP
• Natriumvalproat
• Orfiril
• Pentanoic acid, 2-propyl-, sodium salt (1:1)
• Selenica R
• Sodium 2-propylpentanoate
• Sodium 2-propylvalerate
• Sodium Valproate
• Sodium bispropylacetate
• Sodium dipropylacetate
• Sodium α,α-dipropylacetate
• Valeric acid, 2-propyl-, sodium salt
• Valerin
• Valproate De Sodium
• Valproate sodium
• Valproato De Sodio
• Valproic acid sodium salt
• Valpron
• Vupral

Sodium Valproate

CAS: 1069-66-5

Formula: C₈H₁₅NaO₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 166.20

Ref: 3B-S0894

Sodium valproate

CAS: 1069-66-5

Sodium valproate

Formula: C₈H₁₅NaO₂

Purity: 99.1%

Color and Shape: White To Off White

Molecular weight: 166.09697

Ref: 47-452

SODIUM VALPROATE CRS

CAS: 1069-66-5

SODIUM VALPROATE CRS

Formula: C₈H₁₅NaO₂

Color and Shape: Powder

Molecular weight: 166.1933

Ref: 41-S0930000

Valproic acid sodium salt

CAS: 1069-66-5

Valproic acid sodium salt

Formula: C₈H₁₅NaO₂

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 166.2

Ref: 54-BUP18548

Valproic Acid Sodium Salt

CAS: 1069-66-5

Formula: C₈H₁₅O₂·Na

Molecular weight: 143.21 22.99

Ref: 4Z-V-0666

Sodium valproate

CAS: 1069-66-5

Formula: C₈H₁₅NaO₂

Purity: (Titration) 98.5 - 101.0 % (dried basis)

Color and Shape: White to almost white crystalline powder

Molecular weight: 166.19

Ref: 7W-GK0010

Sodium valproate

CAS: 1069-66-5

Sodium valproate

Formula: C₈H₁₅O₂·Na

Purity: >98%

Color and Shape: Solid

Molecular weight: 166.19327

Ref: 54-OR902840

Valproic acid sodium salt

CAS: 1069-66-5

Sodium valproate is an anti-epileptic, boosting brain GABA levels and possibly affecting potassium channels for membrane stability.

Formula: C₈H₁₅NaO₂

Purity: 98% - 99.85%

Color and Shape: White Solid

Molecular weight: 166.2

Ref: TM-T1602

Sodium 2-Propylpentanoate

CAS: 1069-66-5

Formula: C₈H₁₅NaO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.1933

Ref: IN-DA0035L9

Sodium Valproate

CAS: 1069-66-5

Formula: C₈H₁₅O₂·Na

Color and Shape: White Or Off White

Molecular weight: 166.19

Ref: 61-FOR0751.11

Sodium Valproate

CAS: 1069-66-5

Formula: C₈H₁₅O₂·Na

Color and Shape: Neat

Molecular weight: 166.19

Ref: 86-MM0751.11

Valproic acid sodium

CAS: 1069-66-5

Sodium 2-propylpentanoate

Formula: C₈H₁₅NaO₂

Purity: 97%

Molecular weight: 166.19

Ref: IN-DG41139

Sodium valproate

Controlled Product

CAS: 1069-66-5

Sodium valproate is an anticonvulsant drug that has been used to treat bipolar disorder, epilepsy, and migraine headaches. It is a salt of valproic acid and sodium, with a molecular weight of 266.7. Sodium valproate is available in the form of capsules or tablets that are taken orally. This drug has been shown to have interactions with other drugs such as antibiotics, painkillers, and cholesterol-lowering medicines. Side effects include hypersensitivity syndrome, which may be due to an allergic reaction. Sodium valproate has also been linked to the development of blood clots in veins (thrombosis) and decreased white blood cells (leukopenia). The side-effect profiles of sodium valproate are determined by the pharmacological treatment and dosage level in clinical trials. The efficacy of sodium valproate can be assessed by its ability to reduce seizure frequency or severity in patients with epilepsy when titrated calorimetry is used as the

Formula: C₈H₁₅NaO₂

Color and Shape: White Powder

Molecular weight: 166.19 g/mol

Ref: 3D-FS15501

Sodium 2-(Propyl-1,1-d2)pentanoate-3,3-d2

CAS: 1069-66-5

Formula: C₈H₁₅NaO₂

Molecular weight: 166.19

Ref: BE-MD-6490

Sodium 2-propylpentanoate

CAS: 1069-66-5

Formula: C₈H₁₅NaO₂

Purity: 97%

Molecular weight: 166.196

Ref: 10-F243113

Sodium Valproate

Controlled Product

CAS: 1069-66-5

Stability Hygroscopic
Applications Antiepileptic; increases levels of GABA in the brain.
References Chang, Z.L., et al.: Anal. Profiles Drug Subs., 8, 529 (1979), Nau, H., et al.: Pharmacol. Toxicol., 69, 310 (1991), Loscher, W., et al.: Prog. Neurobiol., 58, 31 (1999)

Formula: C₈H₁₅O₂·Na

Color and Shape: Neat

Molecular weight: 166.19

Ref: TR-S674500

Sodium Valproate

CAS: 1069-66-5

Formula: C₈H₁₅O₂Na

Molecular weight: 143.21 : 23.0

Ref: ST-EA-CP-V6015