CAS 1078166-57-0

1-(4-Fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid

Description:

1-(4-Fluorobenzoyl)-3-[[(6-methoxy-2-naphthalenyl)oxy]methyl]-3-azetidinecarboxylic acid is a synthetic organic compound characterized by its complex structure, which includes an azetidine ring, a fluorobenzoyl group, and a methoxy-substituted naphthalene moiety. The presence of the azetidine ring suggests potential applications in medicinal chemistry, particularly in drug design, due to its ability to mimic natural structures and interact with biological targets. The fluorobenzoyl group may enhance lipophilicity and influence the compound's pharmacokinetic properties, while the methoxy group on the naphthalene ring can affect the compound's electronic properties and reactivity. This compound is likely to exhibit specific biological activities, which would need to be evaluated through experimental studies. Its unique combination of functional groups may also provide opportunities for further chemical modifications, making it a candidate for research in various fields, including pharmaceuticals and materials science. As with any chemical substance, safety and handling precautions should be observed due to potential toxicity or reactivity.

Synonyms:

• Pf 04418948
• 1-(4-Fluorobenzoyl)-3-[(6-Methoxynaphthalen-2-Yl)Oxymethyl]Azetidine-3-Carboxylic Acid

PF 04418948

CAS: 1078166-57-0

Formula: C₂₃H₂₀FNO₅

Purity: %

Color and Shape: Solid

Molecular weight: 409.4070

Ref: IN-DA008TMW

PF-04418948

CAS: 1078166-57-0

PF-04418948

Purity: ≥95%

Molecular weight: 409.41g/mol

Ref: 54-BUP13115

1-(4-Fluorobenzoyl)-3-(((6-Methoxynaphthalen-2-Yl)Oxy)Methyl)Azetidine-3-Carboxylic Acid

CAS: 1078166-57-0

1-(4-Fluorobenzoyl)-3-(((6-Methoxynaphthalen-2-Yl)Oxy)Methyl)Azetidine-3-Carboxylic Acid

Purity: 98%

Molecular weight: 409.41g/mol

Ref: 54-PC108755

PF-04418948

CAS: 1078166-57-0

PF-04418948 is a potent EP2 receptor antagonist. Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors.

Formula: C₂₃H₂₀FNO₅

Purity: 98.67% - 99.45%

Color and Shape: Solid

Molecular weight: 409.41

Ref: TM-T3306

PF 04418948

Controlled Product

CAS: 1078166-57-0

Applications PF 04418948 acts as a novel, potent and selective prostoglandin EP2 receptor antagonist.
References Brit. J. Pharm., 164, 1847 (2011);

Formula: C₂₃H₂₀FNO₅

Color and Shape: Neat

Molecular weight: 409.407

Ref: TR-P218295

PF-04418948

CAS: 1078166-57-0

PF-04418948 is a potent and selective antagonist of the camp receptor. It inhibits the binding of camp to the receptor, thereby inhibiting activation of downstream signaling pathways. PF-04418948 has been shown to inhibit cyclase activity in vitro, which may account for its effects on PGE2 levels. PF-04418948 also prevents cytosolic Ca2+ accumulation by blocking cation channels, which may contribute to its neuroprotective effects. PF-04418948 has been shown to have anti-angiogenic properties in vivo and in vitro experiments. This drug also blocks glutamate release from activated microglia and toll-like receptor signaling pathways, thereby suppressing microbial infection.

Formula: C₂₃H₂₀FNO₅

Purity: Min. 95%

Molecular weight: 409.41 g/mol

Ref: 3D-DTB16657