CAS 1088965-37-0
:GSK-923295
Description:
GSK-923295, with the CAS number 1088965-37-0, is a small molecule that has been investigated primarily for its potential therapeutic applications in the treatment of various diseases, particularly in the field of oncology. It functions as a selective inhibitor of certain protein kinases, which play crucial roles in cell signaling pathways that regulate cell growth, division, and survival. The compound's mechanism of action typically involves the modulation of specific pathways associated with cancer cell proliferation and survival, making it a candidate for targeted cancer therapies. In terms of its physical and chemical properties, GSK-923295 is characterized by its molecular structure, which includes specific functional groups that contribute to its biological activity and solubility. As with many investigational compounds, detailed studies on its pharmacokinetics, toxicity, and efficacy are essential for understanding its potential as a therapeutic agent. Further research is necessary to fully elucidate its characteristics and applications in clinical settings.
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Found 4 products.
GSK-923295
CAS:GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).Formula:C32H38ClN5O4Purity:96.22% - 98.02%Color and Shape:SolidMolecular weight:592.13GSK 923295
CAS:Controlled Product<p>Applications GSK 923295 is the first potent, CENP-E-selective inhibitor that has been tested in Phase I clinical trials for treatment of Refractory Cancers.<br>References Wood, K., et al.: Proc. Natl. Acad. Sci. U. S. A., 107, 5839 (2010); Qian, X., et al.: ACS Med. Chem. Lett., 1, 30 (2010); Lock, R., et al. Pediatr. Blood Cancer, 58, 916 (2012); Mayes, P., et al.: Int. J. Cancer, 132, E149 (2013)<br></p>Formula:C32H38ClN5O4Color and Shape:NeatMolecular weight:592.13GSK 923295
CAS:<p>Inhibitor of mitotic kinesin CENP-E</p>Formula:C32H38ClN5O4Purity:Min. 95%Molecular weight:592.13 g/mol
