CAS: 112887-68-0 - Raltitrexed

Formula: C₂₁H₂₂N₄O₆S

InChI: InChI=1S/C21H22N4O6S/c1-11-22-14-4-3-12(9-13(14)19(28)23-11)10-25(2)17-7-6-16(32-17)20(29)24-15(21(30)31)5-8-18(26)27/h3-4,6-7,9,15H,5,8,10H2,1-2H3,(H,24,29)(H,26,27)(H,30,31)(H,22,23,28)/t15-/m0/s1

InChI key: InChIKey=IVTVGDXNLFLDRM-HNNXBMFYSA-N

SMILES: O=C1N=C(NC2=CC=C(C=C12)CN(C=3SC(=CC3)C(=O)NC(C(=O)O)CCC(=O)O)C)C

Synonyms:

• L-Glutamic acid, N-[[5-[[(1,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-
• N-[[5-[[(3,4-Dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-L-glutamic acid
• L-Glutamic acid, N-[[5-[[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-
• D 1694
• ICI-D 1694

(S)-2-[(1-{5-[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-thiophen-2-yl}-methanoyl)-amino]-pentanedioic acid

CAS: 112887-68-0

• Formula: C₂₁H₂₂N₄O₆S
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 458.4876

Raltitrexed

CAS: 112887-68-0

• Formula: C₂₁H₂₂N₄O₆S
• Molecular weight: 458.49

Raltitrexed

CAS: 112887-68-0

• Formula: C₂₁H₂₂N₄O₆S
• Molecular weight: 458.49

Raltitrexed

CAS: 112887-68-0

• Formula: C₂₁H₂₂N₄O₆S
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 458.49

Raltitrexed-13C-d3

CAS: 112887-68-0

• Formula: C₂₀₁₃CH₁₉D₃N₄O₆S
• Molecular weight: 462.50

Raltitrexed

CAS: 112887-68-0

Raltitrexed (D1694)(IC50 of 9 nM), a thymidylate synthase inhibitor, is used for the inhibition of …

• Formula: C₂₁H₂₂N₄O₆S
• Purity: 98.96% - 99.06%
• Color and Shape: Yellow Crystalline Powder
• Molecular weight: 458.49

Raltitrexed

CAS: 112887-68-0

Applications Folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate …

• Formula: C₂₁H₂₂N₄O₆S
• Color and Shape: Neat
• Molecular weight: 458.49

Raltitrexed

CAS: 112887-68-0

Anti-folate inhibitor of thymidylate synthase

• Formula: C₂₁H₂₂N₄O₆S
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 458.49 g/mol