Estimated delivery in United States, on Tuesday 28 May 2024
Product Information
Name:
Raltitrexed
Controlled Product
Synonyms:
- N-[[5-[[(3,4-Dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-L-glutamic Acid
- L-Glutamic acid
- N-[[5-[[(1,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]- (9CI)
- D 1694
- ICI-D 1694
- N-[[5-[[(3,4-Dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-L-glutamic acid
- TDX
- Tomudex
- ZD 1694
CAS:
Description:
Applications Folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jodrell, D.I., et al.: Cancer Chemother. Pharmacol., 28, 331 (1991), Jackman, A.L., et al.: Eur. J. Cancer, 31A, 1277 (1995)
Brand:
TRC
Long term storage:
Notes:
Chemical properties
Molecular weight:
458.49
Formula:
C21H22N4O6S
Color/Form:
Yellow to Beige Solid
InChI:
InChI=1S/C21H22N4O6S/c1-11-22-14-4-3-12(9-13(14)19(28)23-11)10-25(2)17-7-6-16(32-17)20(29)24-15(21(30)31)5-8-18(26)27/h3-4,6-7,9,15H,5,8,10H2,1-2H3,(H,24,29)(H,26,27)(H,30,31)(H,22,23,28)/t15-/m0/s1
InChI key:
InChIKey=IVTVGDXNLFLDRM-HNNXBMFYSA-N
SMILES:
Cc1nc2ccc(CN(C)c3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)s3)cc2c(=O)[nH]1
MDL:
Melting point:
Boiling point:
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Density:
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EINECS:
Merck:
HS code:
Technical inquiry about: TR-R100500 Raltitrexed
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