CAS 1181081-71-9

CLP257

Description:

CLP257, with the CAS number 1181081-71-9, is a chemical compound that falls under the category of small molecules. While specific details about its characteristics may not be widely available, compounds like CLP257 are often studied for their potential applications in various fields, including pharmaceuticals and materials science. Typically, such substances may exhibit unique structural features, reactivity patterns, and biological activities that make them of interest for research and development. The characteristics of a compound can include its molecular weight, solubility in different solvents, stability under various conditions, and potential interactions with biological systems. Additionally, safety data sheets would provide information on toxicity, handling precautions, and environmental impact. For precise information regarding CLP257, including its physical and chemical properties, consulting specialized databases or scientific literature is recommended, as these resources can provide comprehensive insights into the compound's behavior and applications.

Formula: C₁₄H₁₄FN₃O₂S

InChI: InChI=1S/C14H14FN3O2S/c15-10-4-3-9(11(19)8-10)7-12-13(20)17-14(21-12)18-6-2-1-5-16-18/h3-4,7-8,16,19H,1-2,5-6H2/b12-7-

InChI key: SKCADXVKQRCWTR-GHXNOFRVSA-N

SMILES: C1CCN(NC1)C2=NC(=O)/C(=C/C3=C(C=C(C=C3)F)O)/S2

Synonyms:

• CLP257
• (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone
• 4(5H)-Thiazolone, 5-[(4-fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1(2H)-pyridazinyl)-, (5Z)-

CLP 257

CAS: 1181081-71-9

Formula: C₁₄H₁₄FN₃O₂S

Purity: 98%

Molecular weight: 307.3433

Ref: IN-DA01DZU4

CLP257

CAS: 1181081-71-9

CLP257

Formula: C₁₄H₁₄FN₃O₂S

Purity: ≥98%

Molecular weight: 307.34

Ref: 54-BUP04173

CLP257

CAS: 1181081-71-9

(Z)-5-(4-Fluoro-2-hydroxybenzylidene)-2-(tetrahydropyridazin-1(2H)-yl)thiazol-4(5H)-one

Formula: C₁₄H₁₄FN₃O₂S

Purity: 98%

Molecular weight: 307.34

Ref: IN-DG00795711

(5Z)-5-[(4-FLUORO-2-HYDROXYPHENYL)METHYLENE]-2-(TETRAHYDRO-1-(2H)-PYRIDAZINYL)-4(5H)-THIAZOLONE

CAS: 1181081-71-9

Purity: ≥98%(HPLC)

Molecular weight: 307.3399963

Ref: 10-F844614

CLP 257

Controlled Product

CAS: 1181081-71-9

Formula: C₁₄H₁₄FN₃O₂S

Color and Shape: Neat

Molecular weight: 307.34

Ref: TR-C560013

CLP257

CAS: 1181081-71-9

CLP257 is a selective K+-Cl− cotransporter KCC2 activator (EC50: 616 nM) and it is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4.

Formula: C₁₄H₁₄FN₃O₂S

Purity: 99.5%

Color and Shape: Yellow Solid

Molecular weight: 307.34

Ref: TM-T14984

CLP257

CAS: 1181081-71-9

CLP257 is a synthetic compound characterized as an inhibitor of chloroplastic RNA polymerase. It is derived from a systematic chemical synthesis process involving the rational design of inhibitory molecules targeting chloroplastic transcriptional machinery. This product acts by binding to the RNA polymerase complex, effectively disrupting the transcription process within chloroplasts. The inhibition occurs through allosteric modulation, where CLP257 induces conformational changes that impede the enzyme's ability to synthesize RNA.

Formula: C₁₄H₁₄FN₃O₂S

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 307.34 g/mol

Ref: 3D-GXB08171